Antioxidant activity of gamma-oryzanol mechanism of action and its effect on oxidative stability of pharmaceutical

Caudia Juliano, Massima Cossee, Maria Cristina, Luisella Pia

International Journal of pharmaceutics, Vol.299, Issue 1-2, 11August 2005, 146-154.

 

"Claudia et al. studied in antioxidant activity of gamma-oryzanol. In this research, gamma-oryzanol was extracted from rice bran oil. The molecular mechanism(s) of antioxidant activity of gamma-oryzanol by utilising different in vitro were investigated, such as scavenging at stable DPPH radical, OH radical and O2 radicals scavenging, and azocompound AMVN-initiated lipid peroxidation. The effect of scavenging on the oxidative stability of vegetable oils of pharmaceutical and cosmetic was evaluated in a oxidation accelerate test and compared with the effect of BHA and BHT. It was found that gamma-oryzanol is able to prevent AMVN-triggered lipoperoxidation. Moreover, when added to oil at concentration ranging between 2.5 and 10 mmol/kg, gamma-oryzanol shows a dose-dependant increase of induction time of oil, gamma-oryzanol improved the oxidative stability of oil. "

 

 

Gamma-Oryzanol: an important component in rice bran oil

Scavariello EMS ; Arellano DB

ARCHIVOS LATINOAMERICANOS DE NUTRICION 1998, Vol 48, Iss 1, pp 7-12

 

"gamma-Oryzanol, a mixture of ferulic acid esters of sterol and triterpene alcohols, it occurs in rice bran oil at a level of to 2%,where it serves as natural antioxidant. Recent research has shown that gamma-Oryzanol can lower the cholesterol levels in the blood, lowering the risk of coronary heart disease, besides that also has been used in Japan like natural antioxidant in foods, beverages and cosmetics. This review refers to aspects about gamma-Oryzanol, like its physiochemical properties, its presence in the rice bran oil, its antioxidant and hypocholesterolemic activity, as well as, identification, quantitation and extraction methods. "

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Advanced skin care research has shown that gamma oryzanol, a nutrient extract from rice bran, is effective as an antioxidant, for color correction by lightening & brightening skin, and for replacing nutrients to the skin.
gamma-oryzanol Research
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