Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
I am very happy with my purchase of SKB from BulkActives. Good quality and packaged well. I use SKB in my Vitamin C serum. Will buy from them again. Can't beat the price either! .. ...»
I am very happy with both the quality and packaging of the Ferulic acid I ordered. It came in foil packets (I ordered two). Will buy from them again as I use the product in my Vitamin C serum to maintain the PH needed... ...»
Powered ingredient easy to blend, dissolves easily, no gritty feel, product does however transfer this chemical transdermally and should be thought about prior to mixing as it does effect hormones. Gives skin a quick firm appearance in personal formulations and was a great experimental addition to personal products. The DIY provided on this site is the way to go to try out this product. A little goes a long way... ...»
Hi, Ordered this about 5 weeks ago, so I been waiting to DIY and try the product before I left a review. I mixed Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 Liposome Emulsion, 3/4 tsp, with 3tsps distilled water and 3/4 tsp of rose hip oil. It makes a beautiful light weight serum that I apply at night. You can feel tightening within a few minutes. The tightening subsides in half hour or so and then I apply a moisturiser. Another excellent buy from Bulk Actives. .. ...»
Jan Greenwood
I am very happy with this product, and Bulkactives sells it for 1/3 less the price than other suppliers.. ...»
Costly but great product - fast visible effect of use. Best form of Vitamin C. Big thanks to John for selling this product!.. ...»
Another great find on bulkactives. Mixed with de mineralized water, you have the basis to add to any serum, mix with your moisturiser, to simply use on it's own. Love it... ...»
I started experimenting with DIY skin care about 5-6 months ago, then I found Bulk Actives. A one shop DIY shop. LLA powder is beautiful to work with, easy to dissolve, and price is absolutely to die for. Mixed with other powders and oils it is a great serum. .. ...»
Very finely milled powder, great quality. I don't have difficulty dissolving it in my regular toner. I add FE, HA and Vit E with the mixture to make a serum. Shipping time is as promised. Thank you BulkActives! .. ...»
I've been using glucosamine in combination with niacinamide as an addition to my moisturizer to combat dark spots on face and hands. Used twice daily, it does seem to keep them from darkening. Of course, you still need to be religious about using a sunscreen every time you are in the sun. .. ...»
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About BulkActives

BulkActives are DIY skin care suppliers of skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and standardized botanical extracts for diy skin care products and homemade cosmetics.

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A Shout Out to all dedicated DIY Skin Care Bloggers

If you have a DIY Skin Care recipe you would like create and blog about, we are offering you the ingredients to experiment with for free.

All we ask is that you ONLY use our active ingredients, emulsifiers, bases and preservatives, and that your blog article shows photos of your process, and back links to our product pages.

Interested? Contact, please include your blog URL and the ingredients you would like to use.

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Recent Articles

Buy Alpha Lipoic Acid (RS-ALA) For DIY Skin Care

Alpha Lipoic Acid in skin care:  antioxidant, anti-inflammatory, reduce fine lines and possibly wrinkles, sun damage repair, active ingredient in Perricone MD products

Alpha Lipoic Acid (RS-ALA) is an enzyme that is found in yeast, kidney, liver, spinach and broccoli amongst other sources. It is not only a powerful anti-oxidant but is also believed to have numerous anti-inflammatory properties. Antioxidants are compounds that help the body stop or minimize the effects of oxidation on various body cells. When oxidization occurs, which is simply the reaction between substances and oxygen, it sometimes results in the release of free radicals. Free radicals are essentially unpaired that attack other molecules in an effort to achieve stability. Free radicals attack any neighboring cell structures, setting of chain reactions that result in cell mutations which often result in damage to the cell structures. Antioxidants such as Alpha Lipoic Acid are able to stop these reactions and save the body from these cellular changes.. Alpha Lipoic Acid is also a main ingredient in Perricone MD skin care products.


Alpha lipoic acid skin whitening
Product Code: BulkActives
Reward Points: 5
Assay: 99.83%
CAS#: 1077-28-7
Net weight: 30g /1.06oz
Availability: In Stock ( 5+ Available )
Price: $9.20
Reward Points: 460

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Alpha Lipoic Acid (RS-ALA)

Alpha Lipoic Acid is a powerful antioxidant with anti aging properties. It is often used in skin care products intended to reduce inflammation, improve cellular energy production, and for neutralizing heavy metals. It is currently being tested for anti-aging properties, and shows much promise for reducing fine lines and wrinkles.

About Alpha Lipoic Acid in DIY Skin Care

Alpha Lipoic Acid, which is both water and fat-soluble, meaning it can stay for long in the body, is a good antioxidant which also has the ability to regenerate other antioxidants such as Vitamin C and Vitamin E. Alpha Lipoic Acid’s ability to combat free radicals in the skin means that it is an antioxidant that reduces the impact and effects of photoaging and aids in cancer prevention. Topical application of 3% Alpha Lipoic acid in a lecithin base has been shown to reduce erythema induced by UVB radiation.

The major impact of Alpha Lipoic Acid is as an antioxidant where it has been found to have the following key properties:

  • It has a capacity and ability to chelate metals.

  • It is able to scavenge reactive oxygen species. This means that it is powerful in stopping the chain reactions of free radicals which saves the body from a lot of cellular structure changes and DNA changes.

  • It has the ability to regenerate antioxidants such as Vitamin C and Vitamin E when these have been depleted due to the action of free radicals.

  • It has the ability and capacity to repair the results of oxidation.

Alpha Lipoic Acid side-effects.

Alpha Lipoic Acid does not appear to have any major side-effects. However, higher amounts of Alpha Lipoic Acid may also cause burning or stinging sensations or a mild rash on skin.
Alpha Lipoic Acid is highly sensitive to UV radiation and degrades very quickly in the presence of UV radiation.
Alpa Lipoic acid should therefore be used as a sun damage treatment, NOT a sun damage prevention product.

The effectiveness of Alpa Lipoic acid is believed to be due to its by-product, dihydrolipoic acid (DHLA).

Although DHLA has a more powerful antioxidative effect than Alpa Lipoic acid, it is very unstable and is oxidized in the skin within minutes of application.

Alpa Lipoic acid has become popular due to the fact that it is absorbed in a stable form and after entrance into cells, is immediately converted to DHLA

From alpha Lipoic Acid to dihydrolipoic acid

  • Alpha Lipoic acid is an example of an existing drug whose therapeutic effect has been related to its antioxidant activity. [3]

  • Dihydrolipoic acid [DHLA], formed by reduction of lipoic acid, has more antioxidant properties than does lipoic acid. [3]

  • Both dihydrolipoic acid [DHLA],  and Alpha lipoic acid  have metal-chelating capacity and scavenge ROS, whereas only DHLA is able to regenerate endogenous antioxidants and to repair oxidative damage. [3]

  • Alpha lipoic acid  can act as an antioxidant against the pro-oxidant activity produced by dihydrolipoic acid [DHLA]. [3]

  • Dihydrolipoic acid [DHLA],  has the capacity to regenerate the endogenous antioxidants vitamin E, vitamin C and Glutathione. [3]

  • Alpha lipoic acid  topically applied to skin penetrated readily, and was reduced to  [2]

  • Alpha lipoic acid  was converted rapidly by the cells to dihydrolipoic acid. [1]

  • Alpha Lipoic Acid is an acid and it may irritate. Start of with small amounts. A slight tingling/burning feeling upon application is common, this should go away after a few minutes. If not, remove from face and use a smaller percentage.
  • Alpha Lipoic Acid is highly sensitive to UV radiation and degrades very quickly in the presence of UV radiation. Alpa Lipoic acid should therefore be used as a sun damage treatment, NOT a sun damage prevention product.
Assay: 99.83%
INCI: 1,2-dithiolane-3-pentanoic acid (thioctic acid)
Solubility: oil (mixes in a cream), propolyne glycol
Suggested percentage:3% to 5%

Storage: Cool, dry place. Do not freeze. Keep away from light and moisture!
Country of origin: China

NOTE: We are often asked to stock the R form of ALA, instead of  the R/S (racemix) product we currently stock.  At this stage we are not prepared to do so. As far as we know (and if we are wrong please send us the info) there is no solid published evidence to support the negative comments circulating the use of the S form in skin care products. In addition, the problem with the R form, once isolated from the S, is that it is unstable and extremely sensitive to heat, thus making it entirely unsuitable for shipping (unless send refrigerated) and most importantly DIY skin care.

Topically applied Alpha Lipoic Acid may:

  • prevent or reduce UVA and UVB sun damage: [11] [9] [7] [5] [4]
  • act as an anti oxidant [12] [10] [8] [4] [3]
  • increase collagen production [11]
  • act as an anti inflammatory [8]
12. Matsugo S, Bito T, Konishi T.. Photochemical stability of lipoic acid and its impact on skin ageing. Free Radic Res. 2011 Aug;45(8):918-24. Epub 2011 Jun 9. PMID: 21651453 

11. Tsuji-Naito K, Ishikura S, Akagawa M, Saeki H.  α-Lipoic acid induces collagen biosynthesis involving prolyl hydroxylase expression via activation of TGF-β-Smad signaling in human dermal fibroblasts. Connect Tissue Res. 2010 Oct;51(5):378-87. PMID: 20604712

10. Wada N, Wakami H, Konishi T, Matsugo S.  The Degradation and Regeneration of alpha-Lipoic Acid under the Irradiation of UV Light in the Existence of Homocysteine. J Clin Biochem Nutr. 2009 May;44(3):218-22. Epub 2009 Apr 25. PMID: 19430609 

9. Davis GD, Masilamoni JG, Arul V, Kumar MS, Baraneedharan U, Paul SF, Sakthivelu IV, Jesudason EP, Jayakumar R. Radioprotective effect of DL-alpha-lipoic acid on mice skin fibroblasts.. Cell Biol Toxicol. 2009 Aug;25(4):331-40. Epub 2008 Jun 13. PMID: 18553143

8. Petersen Shay K, Moreau RF, Smith EJ, Hagen TM.  Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. IUBMB Life. 2008 Jun;60(6):362-7. PMID: 18409172 

7. Ho YS, Lai CS, Liu HI, Ho SY, Tai C, Pan MH, Wang YJ. Dihydrolipoic acid inhibits skin tumor promotion through anti-inflammation and anti-oxidation. Biochem Pharmacol. 2007 Jun 1;73(11):1786-95. Epub 2006 Dec 10. PMID: 17403519

6. Lin JY, Lin FH, Burch JA, Selim MA, Monteiro-Riviere NA, Grichnik JM, Pinnell SR. Alpha-lipoic acid is ineffective as a topical antioxidant for photoprotection of  skin.  J Invest Dermatol. 2004 Nov;123(5):996-8. PMID: 15482491 

5.  Beitner H. Randomized, placebo-controlled, double blind study on the clinical efficacy of a cream containing 5% alpha-lipoic acid related to photoageing of facial skin. Br J Dermatol. 2003 Oct;149(4):841-9. PMID: 14616378

4. Podda M, Zollner TM, Grundmann-Kollmann M, Thiele JJ, Packer L, Kaufmann R. Activity of alpha-lipoic acid in the protection against oxidative stress in skin. Curr Probl Dermatol. 2001;29:43-51. PMID: 11225200 

3.  Biewenga GP, Haenen GR, Bast A. The pharmacology of the antioxidant lipoic acid. Gen Pharmacol. 1997 Sep;29(3):315-31. PMID: 9378235 

2. Podda M, Rallis M, Traber MG, Packer L, Maibach HI. Kinetic study of cutaneous and subcutaneous distribution following topical application of [7,8-14C]rac-alpha-lipoic acid onto hairless mice. Biochem Pharmacol. 1996 Aug 23;52(4):627-33. PMID: 8759036 

1.  Handelman GJ, Han D, Tritschler H, Packer L. Alpha-lipoic acid reduction by mammalian cells to the dithiol form, and release into the culture medium. Biochem Pharmacol. 1994 May 18;47(10):1725-30. PMID: 8204089

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