About Ginkgo Biloba in DIY Skin Care
The ginkgo Biloba tree is one of the oldest living species, geological records indicate this plant has been growing on earth for 150 - 200 million years. Chinese monks are credited with keeping the tree in existence, as a sacred herb. It was first brought to Europe in the 1700's. It is one of the well-researched herbs in the world.
The extract of ginkgo leaves is used medicinally in North America, where it's one of the most popular medicinal herbs, and many other countries around the world. In traditional Chinese medicine, the seeds of the ginkgo tree are used.
Research studying the beneficial photoprotective effects of topical formulations containing combined extracts of Ginkgo biloba and green tea showed that formulations containing Ginkgo biloba provided total protection of the skin barrier providing substantial photoprotective effects .
Formulations containing Ginkgo biloba showed great antioxidant and free radical scavenging activities and may be used in topical formulations in order to protect skin against damage caused by free radical and reactive oxygen species.
A study showed that the flavonoids in Ginkgo biloba may be beneficial for treating chronic skin inflammatory disorders such as atopic dermatitis A number of botanical agents such as ginkgo biloba, vitamins E and C and proanthocyanidins have shown to possess cancer chemopreventive qualities.
Ginkgo biloba was shown to increase the levels of superoxide dismutase (SOD() in skin exposed to acute ultraviolet-B (UV-B) radiation.
Ginkgo biloba studies showed the proliferative effectsof the Ginkgo biloba flavonoid fractions: quercetin, kaempferol, sciadopitysin, ginkgetin, isoginkgetin, on the proliferation of normal human skin fibroblast Furthermore, increased production of collagen and extracellular fibronectin were documented.
Topically applied Gingko Biloba may:
- act as an anti-inflammatory:
- repair and treat sun damage:
- prevent or reduce UVA and UVB sun damage:
- increase collagen production
13: Belo SE, Gaspar LR, Campos PM. Photoprotective Effects of Topical Formulations Containing a Combination of Ginkgo biloba and Green Tea Extracts. Phytother Res. 2011 Dec;25(12):1854-60. doi: 10.1002/ptr.3507. Epub 2011 Apr 25. PubMed PMID: 21520309.
12: Liu XP, Goldring CE, Copple IM, Wang HY, Wei W, Kitteringham NR, Park BK. Extract of Ginkgo biloba induces phase 2 genes through Keap1-Nrf2-ARE signaling pathway. Life Sci. 2007 Apr 3;80(17):1586-91. Epub 2007 Jan 27. PubMed PMID: 17316704.
11: Lim H, Son KH, Chang HW, Kang SS, Kim HP. Inhibition of chronic skin inflammation by topical anti-inflammatory flavonoid preparation, Ato Formula. Arch Pharm Res. 2006 Jun;29(6):503-7. PubMed PMID: 16833019.
10: Lim H, Son KH, Chang HW, Kang SS, Kim HP. Effects of anti-inflammatory biflavonoid, ginkgetin, on chronic skin inflammation. Biol Pharm Bull. 2006 May;29(5):1046-9. PubMed PMID: 16651744.
9: Eli R, Fasciano JA. An adjunctive preventive treatment for cancer: ultraviolet light and ginkgo biloba, together with other antioxidants, are a safe and powerful, but largely ignored, treatment option for the prevention of cancer. Med Hypotheses. 2006;66(6):1152-6. Epub 2006 Feb 17. PubMed PMID: 16483725.
8: Di Mambro VM, Fonseca MJ. Assays of physical stability and antioxidant activity of a topical formulation added with different plant extracts. J Pharm Biomed Anal. 2005 Feb 23;37(2):287-95. PubMed PMID: 15708669.
7: Kwak WJ, Han CK, Son KH, Chang HW, Kang SS, Park BK, Kim HP. Effects of Ginkgetin from Ginkgo biloba Leaves on cyclooxygenases and in vivo skin inflammation. Planta Med. 2002 Apr;68(4):316-21. PubMed PMID: 11988854.
6: Aricioglu A, Bozkurt M, Balabanli B, Kilinç M, Nazaroglu NK, Türközkan N. Changes in zinc levels and superoxide dismutase activities in the skin of acute, ultraviolet-B-irradiated mice after treatment with ginkgo biloba extract. Biol Trace Elem Res. 2001 May;80(2):175-9. PubMed PMID: 11437182.
5: Hibatallah J, Carduner C, Poelman MC. In-vivo and in-vitro assessment of the free-radical-scavenger activity of Ginkgo flavone glycosides at high concentration. J Pharm Pharmacol. 1999 Dec;51(12):1435-40. PubMed PMID: 10678500.
4: Bekerecio?lu M, Tercan M, Ozyazgan I. The effect of Gingko biloba extract (Egb 761) as a free radical scavenger on the survival of skin flaps in rats. A comparative study. Scand J Plast Reconstr Surg Hand Surg. 1998 Jun;32(2):135-9. PubMed PMID: 9646361.
3: Lin SY, Chang HP. Induction of superoxide dismutase and catalase activity in different rat tissues and protection from UVB irradiation after topical application of Ginkgo biloba extracts. Methods Find Exp Clin Pharmacol. 1997 Jul-Aug;19(6):367-71. PubMed PMID: 9385585.
2: Kim SJ, Lim MH, Chun IK, Won YH. Effects of flavonoids of Ginkgo biloba on proliferation of human skin fibroblast. Skin Pharmacol. 1997;10(4):200-5. PubMed PMID: 9413894.
1: Dumont E, Petit E, Tarrade T, Nouvelot A. UV-C irradiation-induced peroxidative degradation of microsomal fatty acids and proteins: protection by an extract of Ginkgo biloba (EGb 761). Free Radic Biol Med. 1992 Sep;13(3):197-203. PubMed PMID: 1505777.