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BulkActives are DIY skin care suppliers of skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and standardized botanical extracts for diy skin care products and homemade cosmetics.

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Buy Grape Seed Proanthocyanidins For DIY Skin Care

Grape Seed extract with Proanthocyanidins in skin care:  antioxidant, anti-allergenic, anti-inflammatory, capillary health, increase skin elasticity, sun damage protection, sun damage repair, wound healing support

Grape Seed extract is standardized for the flavanoid Proanthocyanidins. Proanthocyanidins are flavonoids that protect capillary walls and inhibit the enzymes that break down collagen (collagenase), hyaluronic acid (hyaluronidase) and elastin (elastase). Grape Seed Proanthocyanidins act as anti-inflammatory, antihistamines, antiallergenic, and as major free radical scavengers. Grape Seed Proanthocyanidins promote tissue elasticity, help heal injuries, reduce swelling and edema, restore collagen and improve peripheral circulation. Grape Seed Proanthocyanidins prevent bruising, strengthen weak blood vessels and reduce histamine production.
 
Product Code: BulkActives
Reward Points: 3
Assay: 95.56% Proanthocyanidins
CAS#: 84929-27-1
Net weight: 30g /1.06oz
Availability: Out Of Stock
Price: $5.50
Reward Points: 275


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Grape Seed Proanthocyanidins

About Grape Seed Proanthocyanidins in DIY Skin Care

 

Grape Seed Proanthocyanidins Skin CareThe Benefits of Grape Seed Extract for Your Skin

Grape seed extract has been investigated in several studies that were aimed at identifying the key benefits for a healthy skin and potential applications in skin care. This biologically active ingredient revealed its numerous positive effects on skin health, without being associated with any observable adverse effects. The unique combination of antioxidant properties, anti-inflammatory and skin rejuvenating effects makes grape seed extract a valuable cosmetic product.

Grape Seed Extract Reduces the Impact of Oxidative Stress on Skin Cells

As a result of the normal metabolism of the skin, some residual substances, toxins or metabolic byproducts may accumulate in skin cells, which can exert a negative influence on normal biological processes. One type of such negative impact on skin cells is called oxidative stress. Antioxidants are a class of biologically active components that protect cells from oxidative stress, and therefore maintain their structural integrity and function. Without sufficient antioxidants, the excessive oxidative stress can result in DNA damage, inflammation and structural abnormalities in skin cells. Grape seed extract is very abundant in antioxidants that protect skin cells from free radicals and metabolic byproducts, which slows down aging processes and contributes to skin rejuvenation.

Anti-Inflammatory Effects of Grape Seed Extract

Inflammation of the skin occurs as a result of “aggressive” influences that threaten the integrity of skin structures, such as injuries, ultraviolet radiation (sunlight), pollutants, harmful bacteria or viruses, chemicals or contact with insects. Inflammation typically diminishes after the negative influence is removed, but, in some cases, it may persist for a long time. Grape seed extract is an excellent remedy against inflammation. In research studies, this component diminished the inflammatory response mediated through immune cells, diminished the visible swelling, redness and pain.

Grape Seed Extract Protects Against Sunburn Caused by UV Radiation

Sunburn is caused by the prolonged exposure to harmful amounts of UV radiation, especially UVB rays. Ultraviolet radiation causes negative changes in skin structure, such as the formation of free radicals, inflammation and the appearance of abnormal, damaged cells. Excessive exposure to UV radiation makes a person more susceptible to skin cancer, which is why adequate protection is required before the damage becomes extensive and exceeds the capacity of the skin to repair and rejuvenate itself. Grape seed extract is an excellent example of a protective cosmetic ingredient that reduces the impact of UV radiation and prevents sunburn. In several studies, this ingredient reduced the number of abnormal cells after exposure to sunlight, and increased the number of Langerhans cells, which participate in skin repair processes.


Facilitating Wound Healing and Skin Smoothness

Grape seed extract stimulates skin regeneration processes, which involve the activation of young cells and their transformation into mature skin cells that would replace the damaged cells. In this manner, this cosmetic product facilitates a faster healing of wounds through an enhanced skin rejuvenation and skin cell replacement. Moreover, grape seed extract demonstrated the capacity to support the production of collagen and elastin fibers, which improves the elasticity of your skin and facilitates skin firmness and smoothness.
 

 

Assay: 95.56% Proanthocyanidins
CAS#: 84929-27-1
INCI: Grape (Vitis Vinifera) Seed extract
Botanical source: Vitis vinifera (Grape)
Solubility: non-denatured ethanol, Propylene glycol.
Suggested percentage: .5 to 3%
Storage: Store in cool and dry place. Keep away from direct strong light and heat.
Country of origin: China

 

Topically applied Grape Seed Proanthocyandins may:

  • act as an anti-inflammatory: [13] [12] [9] [8] [7]
  • act as an anti oxidant: [14] [12] [10] [9] [7] [6] [5] [2]
  • repair and treat sun damage:  [13] [12] [9] [8] [7]
  • prevent or reduce UVA and UVB sun damage: [14] [13] [11] [10] [9] [7] [4] [3] [2] [1]
  • increase skin elasticity:  [7]
  • support wound healing: [12] [6] [5]

14: Yuan XY, Liu W, Hao JC, Gu WJ, Zhao YS. Topical Grape Seed Proanthocyandin Extract Reduces Sunburn Cells and Mutant p53 Positive Epidermal Cell Formation, and Prevents Depletion of Langerhans Cells in an Acute Sunburn Model. Photomed Laser Surg. 2011 Nov 21. [Epub ahead of print] PubMed PMID: 22103910.  

13: Afaq F, Katiyar SK. Polyphenols: Skin Photoprotection and Inhibition of Photocarcinogenesis. Mini Rev Med Chem. 2011 Oct 28. [Epub ahead of print] PubMed PMID: 22070679. 

12: Hemmati AA, Aghel N, Rashidi I, Gholampur-Aghdami A. Topical grape (Vitis vinifera) seed extract promotes repair of full thickness wound in rabbit. Int Wound J. 2011 Oct;8(5):514-20. doi: 10.1111/j.1742-481X.2011.00833.x. Epub 2011 Aug 4. PubMed PMID: 21816000.  

11: Filip A, Daicoviciu D, Clichici S, Mocan T, Muresan A, Postescu ID. Photoprotective effects of two natural products on ultraviolet B-induced oxidative stress and apoptosis in SKH-1 mouse skin. J Med Food. 2011 Jul-Aug;14(7-8):761-6. Epub 2011 Apr 6. PubMed PMID: 21470043. 

10: Hanausek M, Spears E, Walaszek Z, Kowalczyk MC, Kowalczyk P, Wendel C, Slaga TJ. Inhibition of murine skin carcinogenesis by freeze-dried grape powder and other grape-derived major antioxidants. Nutr Cancer. 2011;63(1):28-38. PubMed PMID: 21108125. 

9: Nichols JA, Katiyar SK. Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms. Arch Dermatol Res. 2010 Mar;302(2):71-83. Epub 2009 Nov 7. Review. PubMed PMID: 19898857; PubMed Central  PMCID: PMC2813915. 

8: Vitseva O, Varghese S, Chakrabarti S, Folts JD, Freedman JE. Grape seed and skin extracts inhibit platelet function and release of reactive oxygen intermediates. J Cardiovasc Pharmacol. 2005 Oct;46(4):445-51. PubMed PMID: 16160595. 

7: Shi J, Yu J, Pohorly JE, Kakuda Y. Polyphenolics in grape seeds-biochemistry and functionality. J Med Food. 2003 Winter;6(4):291-9. Review. PubMed PMID: 14977436.  

6: Khanna S, Venojarvi M, Roy S, Sharma N, Trikha P, Bagchi D, Bagchi M, Sen CK. Dermal wound healing properties of redox-active grape seed proanthocyanidins. Free Radic Biol Med. 2002 Oct 15;33(8):1089-96. PubMed PMID: 12374620. 

5: Sen CK, Khanna S, Gordillo G, Bagchi D, Bagchi M, Roy S. Oxygen, oxidants, and antioxidants in wound healing: an emerging paradigm. Ann N Y Acad Sci. 2002 May;957:239-49. Review. PubMed PMID: 12074976.  

4: Bagchi D, Bagchi M, Stohs SJ, Das DK, Ray SD, Kuszynski CA, Joshi SS, Pruess  HG. Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention. Toxicology. 2000 Aug 7;148(2-3):187-97. PubMed PMID: 10962138. 

3: Bomser J, Singletary K, Meline B. Inhibition of 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin ornithine decarboxylase and protein kinase C by polyphenolics from grapes. Chem Biol Interact. 2000 Jun 15;127(1):45-59. PubMed PMID: 10903418. 

2: Zhao J, Wang J, Chen Y, Agarwal R. Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as  the most effective antioxidant constituent. Carcinogenesis. 1999 Sep;20(9):1737-45. PubMed PMID: 10469619.  

1: Bomser JA, Singletary KW, Wallig MA, Smith MA. Inhibition of TPA-induced tumor promotion in CD-1 mouse epidermis by a polyphenolic fraction from grape seeds. Cancer Lett. 1999 Jan 29;135(2):151-7. PubMed PMID: 10096423. 

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