Grape Seed Proanthocyanidins
About Grape Seed Proanthocyanidins in DIY Skin Care
The Benefits of Grape Seed Extract for Your Skin
Grape seed extract has been investigated in several studies that were aimed at identifying the key benefits for a healthy skin and potential applications in skin care. This biologically active ingredient revealed its numerous positive effects on skin health, without being associated with any observable adverse effects. The unique combination of antioxidant properties, anti-inflammatory and skin rejuvenating effects makes grape seed extract a valuable cosmetic product.
Grape Seed Extract Reduces the Impact of Oxidative Stress on Skin Cells
As a result of the normal metabolism of the skin, some residual substances, toxins or metabolic byproducts may accumulate in skin cells, which can exert a negative influence on normal biological processes. One type of such negative impact on skin cells is called oxidative stress. Antioxidants are a class of biologically active components that protect cells from oxidative stress, and therefore maintain their structural integrity and function. Without sufficient antioxidants, the excessive oxidative stress can result in DNA damage, inflammation and structural abnormalities in skin cells. Grape seed extract is very abundant in antioxidants that protect skin cells from free radicals and metabolic byproducts, which slows down aging processes and contributes to skin rejuvenation.
Anti-Inflammatory Effects of Grape Seed Extract
Inflammation of the skin occurs as a result of “aggressive” influences that threaten the integrity of skin structures, such as injuries, ultraviolet radiation (sunlight), pollutants, harmful bacteria or viruses, chemicals or contact with insects. Inflammation typically diminishes after the negative influence is removed, but, in some cases, it may persist for a long time. Grape seed extract is an excellent remedy against inflammation. In research studies, this component diminished the inflammatory response mediated through immune cells, diminished the visible swelling, redness and pain.
Grape Seed Extract Protects Against Sunburn Caused by UV Radiation
Sunburn is caused by the prolonged exposure to harmful amounts of UV radiation, especially UVB rays. Ultraviolet radiation causes negative changes in skin structure, such as the formation of free radicals, inflammation and the appearance of abnormal, damaged cells. Excessive exposure to UV radiation makes a person more susceptible to skin cancer, which is why adequate protection is required before the damage becomes extensive and exceeds the capacity of the skin to repair and rejuvenate itself. Grape seed extract is an excellent example of a protective cosmetic ingredient that reduces the impact of UV radiation and prevents sunburn. In several studies, this ingredient reduced the number of abnormal cells after exposure to sunlight, and increased the number of Langerhans cells, which participate in skin repair processes.
Facilitating Wound Healing and Skin Smoothness
Grape seed extract stimulates skin regeneration processes, which involve the activation of young cells and their transformation into mature skin cells that would replace the damaged cells. In this manner, this cosmetic product facilitates a faster healing of wounds through an enhanced skin rejuvenation and skin cell replacement. Moreover, grape seed extract demonstrated the capacity to support the production of collagen and elastin fibers, which improves the elasticity of your skin and facilitates skin firmness and smoothness.
Topically applied Grape Seed Proanthocyandins may:
- act as an anti-inflammatory:     
- act as an anti oxidant:        
- repair and treat sun damage:     
- prevent or reduce UVA and UVB sun damage:          
- increase skin elasticity: 
- support wound healing:   
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9: Nichols JA, Katiyar SK. Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms. Arch Dermatol Res. 2010 Mar;302(2):71-83. Epub 2009 Nov 7. Review. PubMed PMID: 19898857; PubMed Central PMCID: PMC2813915.
8: Vitseva O, Varghese S, Chakrabarti S, Folts JD, Freedman JE. Grape seed and skin extracts inhibit platelet function and release of reactive oxygen intermediates. J Cardiovasc Pharmacol. 2005 Oct;46(4):445-51. PubMed PMID: 16160595.
7: Shi J, Yu J, Pohorly JE, Kakuda Y. Polyphenolics in grape seeds-biochemistry and functionality. J Med Food. 2003 Winter;6(4):291-9. Review. PubMed PMID: 14977436.
6: Khanna S, Venojarvi M, Roy S, Sharma N, Trikha P, Bagchi D, Bagchi M, Sen CK. Dermal wound healing properties of redox-active grape seed proanthocyanidins. Free Radic Biol Med. 2002 Oct 15;33(8):1089-96. PubMed PMID: 12374620.
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2: Zhao J, Wang J, Chen Y, Agarwal R. Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as the most effective antioxidant constituent. Carcinogenesis. 1999 Sep;20(9):1737-45. PubMed PMID: 10469619.
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