Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
Reviews
I am 69 and I have used this product for two years almost every day at a high dose, adding it to my antioxidant day cream, with excellent results. For me it has a very high quality and effectiveness: reduction of wrinkles, hydrated skin, unified color without blemishes ... A product of 10, the same score that I give to John for the quality of the products he sells, his excellent description / use and the bibliographic contribution.En .. ...»
María Jesus
Really loving this product. I make the best Centella toner and most concentrated ever. 2 g of centella extract dissolved in 10g of alcohol(you have to stir a lot) plus 88 grams of water and you get a very concentrated toner. Creams, toners, ampoules... all have only 0,1% of triterpenes, this toner i make have 1,4%. I am loving it, will see the results. .. ...»
Francisco
excellence product, very good and made my skin soft and smooth just like baby's skin. Thank you john.. ...»
nky
The Pre-dissolved solution is excellent. Ferulic Acid is an amazing skincare ingredient (potent antioxidant, protects other sensitive antioxidants from light degradation, UV protection) but is absolutely ineffective if it isn't solubilized correctly. Makes adding to any Serum Base or w/o emulsion easy. Love using it (at 6%; so active 0.5%) with the Resveratrol Fluid (10%; active 1%) and Green Tea Extr for potent nighttime brightening treatment... ...»
James
I wished i could order this in a smaller amount of 50 gr. Can i get informed when it is available ? -------------------- A. It will not be sold in smaller amounts. The review rating is meant to be for the product, not the size in which it is sold :-(.. ...»
Diana
Excellent quality, very fine texture and disperses easily when used correctly. Arrived in just seven days to London, England and with a reasonable postage fee. Very pleased... ...»
D N Bay
The best, most potent and most stable form of Vitamin C. Makes quite a difference to the appearance of mature, photo-damaged skin - don't expect results over night but with consistent use your skin will look more even and radiant!.. ...»
Judy
I bought this product before and I am here to buy it again! A high quality product for really good price... .. Thanks!.. ...»
Raisa
Love the fine powder ascorbic acid. I use it in a recipe for skin care along with hyaluronic acid. I'm 65 years old and absolutely no one believes it 'cause I've been doing this for years... ...»
Kathy
As all products from bulkactives, this is a really great and high-quality DYI ingredient. Along with John's friendly, reliable and very efficient service, it makes a purchase from bulkactives a very pleasant experience... ...»
Sandra
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stimulate collagen production

Collagen Synthesis: stimulate collegen production in skin care

Collagen is the primary structural protein found in skin, and is comprised of long, fibrous strings of amino acids. Therefore, it can greatly affect the firmness and smoothness of skin. Collagen is formed by specialized cells in the dermis called fibroblasts. When stimulated by molecules known as fibroblast growth factors, they synthesize small subunits of collagen, known as procollagen. These subunits are then transported out of the cell where they are strung into long chains that resemble fibers.

However, merely having a lot of collagen does not necessarily result in the desired effects; there are twelve different types of collagen, so the overall appearance of skin is affected not only by the amount of collagen present, but the way these types interact with each other as well. The different types of collagen and their function are displayed below.

 
Type I Found in organs, skin, and tendons. Type most responsible for skin appearance. Also makes up a large percentage of scar tissue.
Type II, IX, X, XI Found in cartilage.
Type III Most abundant during youth. Very similar to Type I in its effect on skin appearance
Type IV Found in the filtration membranes of capillaries.
Type V, VI Found with Type I.
Type IV Found in the filtration membranes of capillaries.
Type VIII Found in the lining of blood vessels.
Type XIII Works with Type I and Type III.













 Unfortunately, even having the right mix of different collagens is not sufficient to make skin look healthy. The structure of the collagen itself is the most important factor resulting in smoother skin that has less wrinkles. When collagen is first synthesized, the structure of the protein is at first very orderly. Damage to collagen disrupts this orderly structure and give the long amino acid chains an uneven shape. This damage happens because of sun damage, free radicals found in the environment as well as the body, smoking, and even the hyperglycemia which can result in the formation of Type II diabetes.

collagen formation and synthesis in skin careAge also results in degradation; while collagen is constantly being synthesized, the rate of degradation will overtake the rate of synthesis starting at around age 40. While there are some topical products which use collagen, the molecules that make up this protein are too large to be absorbed into the skin. Therefore, the only effective products are ones that stimulate the body to create its own collagen.

There are many products which can induce collagen synthesis. Vitamin C (ascorbic acid) has been demonstrated to be one of the best compounds for stimulating collagen growth, and in fact, Vitamin C is a necessary fibroblast growth factor. Without it, collagen cannot be synthesized at all. Other small amino-acid chains called peptides also play an important part in stimulating fibroblasts to start producing procollagen.

These proteins are smaller than collagen molecules, so when they are introduced into the body, it is “tricked” into thinking that collagen is being broken down and that it therefore needs to create more.  The peptides  Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 (marketed as matrixyl 3000) were shown to significantly stimulate synthesis of Collagen-I, -IV, -VII, -XVII and Nidogen-I proteins.
 
Numerous  standardized botanical extracts have been studied and evaluated for their ability to stimulate collagen synthesis.  Centella asiatica was shown to increase both collagen and hydroxyproline content (one of the building blocks of collagen) in cells and extracellular areas [4][5][6][7]. Ferulic acid was shown to restore collagen synthesis after UV exposure [8], prevent collagen degradation, and restore normal thickness of the epidermis [9]Gamma oryzanol was shown to inhibit collagen-degrading enzymes – in this respect, rice bran extract is even more potent than vitamin C [10]. Creatine and lactic acid (alpha-hydroxy acid) have also been demonstrated to result in a reduction in wrinkles and “sagginess” of skin by increasing collagen synthesis [2], [1], [3].

It should also be noted that after approximately age 60, the skin has a very difficult time synthesizing collagen. Regardless, it is advisable to continue to invest in products intended for that effect. In addition, the best way to maintain skin is to reduce the number of chemical reactions that damage its structure. Enzymes that break down collagen into smaller proteins are called matrix metalloproteinases (MMPs). New products are currently being developed in order to limit the activity of MMPs. It is likely that, other than stimulating collagen synthesis, targeting MMPs will become the most effective way of retaining skin’s structure.

References:

[1]  Peirano, R.I., et al., Dermal penetration of creatine from a face-care formulation containing creatine, guarana and glycerol is linked to effective antiwrinkle and antisagging efficacy in male subjects. J Cosmet Dermatol, 2011. 10(4): p. 273-81.
[2]  Silva, G.M. and P.M. Maia Campos, Histopathological, morphometric and stereological studies of ascorbic acid and magnesium ascorbyl phosphate in a skin care formulation. Int J Cosmet Sci, 2000. 22(3): p. 169-79.
[3]  Tung, R.C., et al., alpha-Hydroxy acid-based cosmetic procedures. Guidelines for patient management. Am J Clin Dermatol, 2000. 1(2): p. 81-8.
[4]  W. Bylka, P. Znajdek-Awiżeń, E. Studzińska-Sroka, A. Dańczak-Pazdrowska, and M. Brzezińska, “Centella asiatica in dermatology: an overview,” Phytother. Res. PTR, vol. 28, no. 8, pp. 1117–1124, Aug. 2014.
[5]  Sunilkumar, S. Parameshwaraiah, and H. G. Shivakumar, “Evaluation of topical formulations of aqueous extract of Centella asiatica on open wounds in rats,” Indian J. Exp. Biol., vol. 36, no. 6, pp. 569–572, Jun. 1998.
[6]   A. Shukla, A. M. Rasik, G. K. Jain, R. Shankar, D. K. Kulshrestha, and B. N. Dhawan, “In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica,” J. Ethnopharmacol., vol. 65, no. 1, pp. 1–11, Apr. 1999.
[7]  P. Hashim, “The effect of Centella asiatica, vitamins, glycolic acid and their mixtures preparations in stimulating collagen and fibronectin synthesis in cultured human skin fibroblast,” Pak. J. Pharm. Sci., vol. 27, no. 2, pp. 233–237, Mar. 2014.
[8]  V. Staniforth, W.-C. Huang, K. Aravindaram, and N.-S. Yang, “Ferulic acid, a phenolic phytochemical, inhibits UVB-induced matrix metalloproteinases in mouse skin via posttranslational mechanisms,” J. Nutr. Biochem., vol. 23, no. 5, pp. 443–451, May 2012.
[9]  D.-W. Cho, D.-E. Kim, D.-H. Lee, K.-H. Jung, B.-S. Hurh, O. W. Kwon, and S. Y. Kim, “Metabolite profiling of enzymatically hydrolyzed and fermented forms of Opuntia ficus-indica and their effect on UVB-induced skin photoaging,” Arch. Pharm. Res., vol. 37, no. 9, pp. 1159–1168, Sep. 2014.
[10]  A. Manosroi, R. Chutoprapat, M. Abe, W. Manosroi, and J. Manosroi, “Anti-aging efficacy of topical formulations containing niosomes entrapped with rice bran bioactive compounds,” Pharm. Biol., vol. 50, no. 2, pp. 208–224, Feb. 2012.
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Ascorbic Acid -L  (ultra fine powder)

L-ascorbic acid (vitamin C) is an essential nutrient which has many cosmetic benefits. It is a remarkable antioxidant and can scavenge reactive oxygen species and other free radicals, protecting the skin from oxidative stress. It can stimulate collagen synthesis by promoting cross-linking and stabilizing collagen molecules, upregulating collagen genes, increasing the transcription of the tissue inhibitor of matrix metalloproteinase 1, and inducing fibroblast proliferation. It reduces pigmentation by suppressing tyrosinase, which is important for melanin production. It is an anti-inflammatory agent and can be used to treat inflammatory skin disease such as erythema. Together, L-ascorbic acid provides powerful anti-aging properties and has been shown to reduce wrinkles, improve elasticity, and protect against sun damage. Stability and absorption of L-ascorbic acid is a concern. While the anhydrous L-ascorbic acid might be the most stable form, adding vitamin E not only helps stabilizing L-ascorbic acid, but the two have synergistic effects on anti-aging.  Used in: philosopy's turbo booster c powder and SkinCeuticals.

Key benefts of L-ascorbic acid in skin care:

  • Anti-inflammatory [31]
  • Antioxidant [4] [5] [6] [7] [8]
  • Increase skin elasticity [26]
  • Lightening and brightening [4] [22] [28] [29] [30]
  • Matrix metalloproteinases (MMP) inhibitors [19]
  • Moisturizing and hydration [21]
  • Reduce fine lines and wrinkles [7] [21] [22] [25] [26]
  • Ttimulate collagen production [5] [13] [14] [15] [16] [17] [18] [19] [20] [21] [22] [23] [24]
  • Sun damage protection [9] [11]
  • Sun damage repair [6] [22] [26]
  • Teat hyperpigmentation [4] [9] [22] [25] [28] [29] [30]
  • Wrinkle relaxers [22]
$7.10
Based on 4 reviews.
Ascorbyl Glucoside (Ascorbic Acid 2- Glucoside)
Ascorbyl glucoside (AA-2G) is a vitamin derivative, produced biologically by the reaction between glucose and vitamin C. This addition confers greater stability, compared to relatively unstable pure ascorbic acid, thus allowing for wide usage in pharmacy and cosmetics. AA-2G retains the antioxidant properties of the unmodified vitamin, therefore it is used to prevent radiation damage, cell senescence and skin darkening. It also promotes collagen synthesis, as well as cell proliferation – these mechanisms help improve the appearance of the skin and reduce wrinkles. Furthermore, since AA-2G does not release ascorbic acid instantly, all the listed positive effects are sustained longer and the possibility of adverse effects is reduced, compared to using pure ascorbic acid. All these qualities make AA-2G the most attractive vitamin C derivative for cosmetic use.

Key benefits of Ascorbyl glucoside (AA-2G)  in skin care:

  • Antioxidant [10] [16]
  • Lightening and brightening [14]
  • Treat hyperpigmentation [14]
  • Sun damage repair [10] [16]
  • Sun dammage protection [7] [9]
  • Stimulate collagen production [3] [13]
  • Reduce fine lines and wrinkles [12]
$21.30
Ascorbyl Tetraisopalmitate

Ascorbyl tetraisopalmitate (Tetrahexyldecyl Ascorbate) is a molecule derived from vitamin C and isopalmitic acid. Pure vitamin C has several drawbacks for cosmeceutical use, most important of which is the low stability. Chemically modified vitamin molecules are more stable, and pure vitamin is released from the derivatives inside the body. Therefore, the effects of Ascorbyl Tetraisopalmitate are similar to those of vitamin C, most importantly it is able to act as an antioxidant. Ascorbyl tetraisopalmitate reduces the production of oxidizing agents, which contribute to cell damage after exposure to UV or chemical hazards. This effect is even stronger in the modified molecule than in pure vitamin C. Additionally, Ascorbyl Tetraisopalmitate protects against DNA damage and skin darkening caused by UV exposure. Finally, skin visual appearance is also improved by Ascorbyl tetraisopalmitate, as it promotes collagen synthesis and acts as a hydrating agent in reducing skin roughness.

Key benefits of Ascorbyl tetraisopalmitate in skin care:

  • Sun damage protection [1] [2] [7]
  • Sun damage repair [2]
  • Antioxidant [1] [6]
  • Moisturizing and hydration [5]
  • Stimulate collagen production [2]
  • Lightening & brightening [1]
  • treat hyperpigmentation [1]
$86.90
Based on 3 reviews.
Boswellia serrata (Boswelic acid)
Resin from the Boswella serrata tree found in parts of Asia and Africa is commonly used in traditional Ayurvedic medicine for a variety of disorders associated with inflammation. It has been used medicinally for centuries and is now gaining support through research. The main ingredients of the resin are boswellic acids. Boswellic acids have anti-inflammatory effects when applied topically. Preparations using either the resin or pure boswellic acid extracted from the resin can help treat inflammatory disorders such as osteoarthritis, eczema, and psoriasis. The extract helps reduce sun damage, fine lines, and acne. It stimulates collagen production. Also, it aids in wound healing and inhibits tumor growth. Research shows boswella serrata extract has a variety of useful anti-inflammatory effects and can help alleviate the symptoms of a variety of conditions. This extract has been popularized as Boswelox™ by L’Oreal and its Wrinkle-de-crease.

NOTE: To assist you with solubility issues, we now also sell Boswellia serrata (Boswelic acid) as a liquid standardized pre-dissolved solution. Just add the liquid to your cream and mix well.
  • 16% solution gives 1% Boswelic Acid content in final product.
  • 46% solution gives 3% Boswelic Acid content in final product.
  • 66% solution gives 5% Boswelic Acid content in final product.

Key benefits of Boswellia serrata in skin care:

  • Anti-inflammatory [1] [2] [3] [4] [5] [6] [7] [8] [9] [10]
  • Sun damage repair [1] [5]
  • Stimulate collagen production [1]
  • Reduce fine lines [1] [5]
  • Anti-bacterial [10]
  • Anti-acne [10]
  • Tumor inhibition [3]
  • Wound healing support [4]
$7.75
Centella asiatica (Gotu Kola)

Centella asiatica is a tropical plant that has been used extensively in Indian medicine. It has diverse applications for skin cosmetics: firstly, it is effective in wound care, as it promotes healing of simple, infected, non-healing, or burn wounds, as well as wounds in patients with diabetes, undergoing radiotherapy or steroid medication. Centella is also used for treating scars and preventing or reducing stretch marks. The extract of this plant promotes synthesis of collagen, hydroxyproline, hyaluronic acid and cell growth factors, thus helping to maintain the elasticity, strength and general appearance of healthy skin. It also protects the skin from ageing damage, such as glycation, and UV damage, likely by activating antioxidant synthesis.

NOTE: To assist you with solubility issues, we now also sell Centella asiatica as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 15% solution gives 1% triterpenes content in final product.
  • 43% solution gives 3% triterpenes content in final product.
  • 72% solution gives 5% triterpenes content in final product.
     

Key benefits of Centella asiatica in skin care:

  • Wound healing support [1] [2] [4] [5] [8]
  • Stimulate HA production [2]
  • Stimulate collagen production [2] [4] [5] [7]
  • reduce fine lines and wrinkles [2] [4] [5] [7]
  • Increase skin elasticity [2]
  • Glycation inhibitor and repair [9]
  • Scar care [2] [4] [12]
  • Sun damage protection [9]
$37.80
Based on 3 reviews.
CoQ10 (CoEnzyme Q10)

Coenzyme Q10 is a molecule naturally involved in energy metabolism in all human cells. Among its many benefits, the antioxidant properties are the most researched. This molecule can prevent oxidation damage to water-insoluble molecules, DNA mutations, collagen synthesis decrease, pigmentation, inflammation and other adverse effects associated with UV exposure and ageing. In combination with vitamin E or other antioxidants, an exceedingly strong antioxidative effect can be achieved. Furthermore, coenzyme Q10 has a unique capability to protect against infrared A radiation, which is also found in sunlight. The promotion of collagen synthesis makes this coenzyme useful in treating ageing-associated skin changes, such as wrinkle appearance. Finally, its anti-inflammatory effect is beneficial not only for UV-damaged skin, but also for wound healing support.

NOTE: To assist you with solubility issues, we now also sell CoQ10 (Coenzyme Q10) as a liquid standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

Key benefits of Coenzyme Q10 in skin care:

  • Sun damage protection [5] [7] [9]
  • Antioxidant [1] [3] [4] [5] [6] [7] [8]
  • Increase cellular energy production [15]
  • Stimulate collagen production [5] [8] [10] [13]
  • Lightening & brightening [10]
  • Sun damage repair [5] [7] [8]
  • Reduce fine lines & wrinkles [5] [11]
  • Wound healing support [13]
  • Anti-inflammatory [6] [10] [12] [13]
$17.20
Creatine Pyruvate
Creatine is a molecule synthesized naturally in the human body. It is most important in tissues where energy-requiring activities occur, as it is involved in maintaining constant energy flow inside the cell.  It was show to protect skin from degeneration during ageing: creatine activates collagen synthesis, in this way decreasing the amount of wrinkles, and restoring skin firmness, smoothness and elasticity. Cheek sagging can also be reduced by applying creatine-containing cream. Another important benefit of creatine is UV damage protection, as it helps to protect cellular structures (especially mitochondria) from oxidative stress and mutations. Furthermore, creatine-treated skin was shown to regenerate faster. However, to protect creatine itself, pairing with coenzyme Q10 or other antioxidants is advised.

Key benefits of Creatine in skin care:

  • Sun damage protection [6] [7] [8] [9]
  • Sun damage repair [6] [7]
  • Increase cellular energy production [1] [3] [7]
  • Increase skin elasticity  [6]
  • Reduce fine lines and wrinkles [2] [6]
  • Stimulate collagen production [2] [4]
$9.40
Ethyl Ascorbic Acid

Ethyl ascorbic acid is a molecule produced by modifying ascorbic acid, commonly known as vitamin C. This modification is done to increase the molecule’s stability and enhance its transport through skin, as pure vitamin C is easily degraded. In the body, the modifying group is removed and vitamin C is restored in its natural form. Thus, ethylascorbic acid retains the benefits of vitamin C, such as antioxidant activity. Furthermore, it is even more potent in reducing skin darkening after UV exposure. It even has some additional effects, not observed in pure ascorbic acid, such as promoting nerve cell growth or reducing chemotherapy damage. Finally, the slower release also ensures that no toxic effects are observed when using this vitamin C derivative.

Key benefits of Ethyl ascorbic acid in skin care:

  • Stimulate collagen production [5] [6]
  • Lightening & brightening [5] [7] [9] [9]
  • Treat hyperpigmentation [5] [7] [8] [9]
  • Sun damage protection [8] [9]
$17.50
Based on 1 reviews.
Ferulic acid (Natural)
Ferulic acid is a plant compound with numerous known health benefits. It is absorbed efficiently through skin, where it is effective as a strong antioxidant. Most often it is used in combination with vitamins C and E – this way, the individual benefits of each ingredient are strengthened, resulting in very effective UV protection. This combination even prevents DNA damage and cancer formation. The antioxidant protection is stable, remains safe from rubbing and sweating, and even resistant to natural chemical degradation, giving the product a long shelf-life. Ferulic acid alone is also beneficial, as it can restore collagen synthesis after UV exposure and thus reduce the symptoms of skin ageing. These properties make it a desirable component in sunscreens and antioxidant formulations.

NOTE: To assist you with solubility issues, we now sell Ferulic acid in three liquids: pre-dissolved solution, lipsome microemulsion, and ethosome microemulsion. Just add the liquid to your cream and mix well.
  • 6% pre-dissolved solution gives 0.5% Ferulic Acid content in final product.
  • 31% pre-dissolved solution gives 3% Ferulic Acid content in final product.
  • 51% pre-dissolved solution gives 5% Ferulic Acid content in final product.
Ferulic acid is commonly used in the Skinceuticals C+E Ferulic serum.  C E Ferulic is a revolutionary antioxidant combination that delivers advanced protection against photoaging by neutralizing free radicals, boosting collagen synthesis, and providing unmatched antioxidant protection. More protection means more youthful looking skin and better defense against environmental aging.

Key benefits of Ferulic acid in skin care:

  • Sun damage protection [4] [5]] [6] [7] [8] [9] [10]
  • Sun damage repair [9] [10] [13] [14]
  • Antioxidant [1] [3] [7] [8] [9]
  • Stimulate collagen production [13] [14]
  • Lightening & brightening [15]
  • Anti-androgenetic alopecia [3]
  • Stabilizes l ascorbic acid [5]
$8.35
Based on 2 reviews.
Fucoidan
Fucoidan is a dietary fiber extracted from brown seaweed which belongs to a class of fucose-enriched sulphated polysaccharides. Fucoidan has been used for many years in traditional Asian medicine as an anti-coagulant, anti-thrombotic, anti-cancer agent, and to modify immune responses. Topical formulations have recently been investigated for various therapeutic and cosmetic uses.  Due to anti-inflammatory and procollagen synthesis-stimulating properties, fucoidan holds promise for use healing burns, alleviating allergic reactions, and treating atopic dermatitis.  Additionally, fucoidans can increase dermal fibroblast migration and their rate of proliferation.  In several experimental approaches, fucoidan has been shown to successfully reduce the appearance of aging and to promote hair regeneration.  Fucoidan is also present in our seakelp biofermentl, but this powder fucoidan is standardized for 85% of the active ingredient.

NOTE: To assist you with solubility issues, we now also sell Fucoidan as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

Key benefits of Fucoidan in skin care:

  • Anti-inflammatory [1] [4] [8] [9] [10] [11]
  • Scar care [5] [6] [7]
  • Wound healing support [5] [6] 7]
  • Stimulate collagen production [2] [15] [16] [18]
  • Reduce fine lines and wrinkles [2, 15, 16, 18]
  • Moisturizing and hydration [15] [16] [18]
  • Increase skin elasticity [6]
  • Sun damage repair [16] [17]
  • Matrix metalloproteinases (MMP) inhibitors [15] [17]
  • Anti-androgenetic alopecia [18]
$25.60
Gamma oryzanol

Gamma-oryzanol is an ingredient produced from rice bran. It contains several related molecules, build on a ferulic acid backbone, all of which share antioxidant properties. They are particularly useful in protecting lipids, such as oils, which makes oryzanol an attractive ingredient in oil-containing preparations. Furthermore, it helps reduce skin darkening from UV exposure, as well as ageing-related skin symptoms, such as roughness and wrinkling. Since gamma-oryzanol activates sebum glands, it can be used for alleviating various conditions causing dry skin. In respect to collagen degradation, oryzanol can slow down this process even more efficiently than vitamin C, thus resulting in thicker and smoother skin. At the moment, even more possible applications of oryzanol are being investigated, such as treating hair loss or preventing damage from chemotherapy. As gamma oryzanol is oil soluble, it is an ideal active to use instead of pure ferulic acid (which is alcohol soluble).

Key benefits of Gamma oryzanol in skin care:

  • Sun damage protection [4] [9] [11]
  • Antioxidant [2] [3] [5]
  • Increase skin elasticity [9]
  • Oil/sebum control [6]
  • Moisturizing and hydration [5] [6] [9]
  • Stimulate collagen production [9]
  • Lightening & brightening [9] [11]
  • Anti-androgenetic alopecia [12]
$11.30
Ginkgo Biloba

Ginkgo biloba is a unique tree species. Its leaf extract contains a diverse variety of molecules useful in cosmetics and pharmacology. Firstly, they are potent antioxidants, and can even activate the production of enzymes that neutralize free radicals. Combined with the anti-inflammatory effects, this extract provides an effective defense against UV radiation and ageing symptoms. Dermal applications of this extract can even lead to protection of other organs. Another major application of Ginkgo biloba is moisturizing the skin, which helps to increase its elasticity and visual appearance, even reducing the amount of wrinkles. Furthermore, this extract helps to maintain the barrier function of the skin – it reduces water loss through epidermis, thus reducing skin dryness and irritation. In combination with green tea extract, Ginkgo shows even stronger benefits in these areas.

NOTE: To assist you with solubility issues, we now also sell Ginkgo Biloba extract as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

Key benefits of Ginkgo Biloba in skin care:

  • Sun damage protection [1] [6] [8] [10] [11]
  • Sun damage repair [7] [10]
  • Antioxidant [1] [6]
  • Capillary health [6] [14]
  • Increase skin elasticity [2]
  • Moisturizing & hydration [2] [3] [4]
  • Restore barrier function [2] [3] [4] [5]
  • Reduce fine lines and wrinkles [2] [4] [9]
  • Anti-inflammatory [9] [12] [13]
$10.95
Glucosamine (N-Acetyl Glucosamine)

N-acetyl glucosamine is a compound with a wealth of uses for improving skin condition. It is a known precursor to hyaluronic acid, a major component of skin structure. Hyaluronic acid is essential for hydration and n-acetyl glucosamine has been shown to increase moisture. N-acetyl glucosamine helps heal wounds, increase collagen, and reduce acne. It reduces hyperpigmentation, especially when combined with niacinamide, a member of the vitamin B3 family. It has anti-oxidant and anti-inflammatory properties which allow it to help heal and prevent sun damage. Overall, this compound can help prevent premature aging and reduce signs of aging, such as wrinkles, especially when combined with niacinamide.

Key benefits of Glucosamine in skin care:

  • Stimulate HA production [2] [3] [4] [5] [6] [7] [8] [9] 10]
  • Moisturizing and hydration [2] [5] [9] [11]
  • Treat hyperpigmentation [2] [4] [9]
  • Wound healing support [2] [11]
  • Stimulate collagen production [11]
  • Scar care [2]
  • Anti-acne [2] [6]
  • Anti-inflammatory [2] [3]
  • Anti-oxidant [2] [7]
  • Sun damage repair [1] [7]
  • Sun damage protection [7]
  • Increase skin elasticity [5] [11]
  • Reduce fine lines and wrinkles [2] [10]
  • Matrix metalloproteinases [MMP] inhibitors [7]
$8.20
Based on 1 reviews.
Lactic Acid -L(+) (Alpha Hydroxy Acid)
Alpha hydroxyl acids [AHAs] such as lactic acid have been used traditionally to improve the feel and complexion of the skin.  While glycolic acid has been the conventional AHA used in skin care products, lactic acid has ranked even with or outperformed lactic acid in every category and is the only AHA to maintain such success over the course of twenty-two weeks.  Lactic acid is a known exfoliant which can slough off dull skin to leave a brighter complexion.  It can also increase the synthesis of lipids and ceramides, thereby fortifying the skin barrier function and reducing water loss.  Further, lactic acid is correlated to increased hyaluronic acid and collagen synthesis, resulting in skin that is more hydrated, softer and firmer, and with fewer fine lines and wrinkles.  Topical application of lactic acid also can reduce the synthesis of melanin and decrease the appearance of hyperpigmentation or age spots.  Incorporation of lactic acid in skin care products can lighten and brighten skin while improving dermal health and reducing the appearance of photoaging.

Key benefits of Lactic acid in skin care:

  • Capillary health [10], [12]
  • Increase skin elasticity [1] [2] [8] [9]
  • Lightening & brightening [1] [2] [4]  [9]  [11]
  • Moisturizing and hydration [6] [7]
  • Reduce fine lines and wrinkles [1] [2] [8] [9]
  • Restoring barrier function [5] [6] [7]
  • Stimulate collagen production [9]
  • Stimulate HA production [8] [9]
  • Sun damage repair [1] [2] [8] [9]
  • Treat hyperpigmentation [2] [9]
$6.90
Niacinamide (Vitamin B3)
Niacinamide, also known as nicotinamide, is a water soluble form of vitamin B3. Vitamin B3 is essential for maintaining skin health. Niacinamide increases production of important skin structural components such as collagen, ceramide, and keratin. This helps increase moisture and strengthen skin. Niacinamide is known to decrease hyperpigmentation, effectively lightening and brightening skin, especially when used together with n-acetyl glucosamine, a hyaluronic acid precursor. It reduces wrinkles and again, this effect is better with n-acetyl glucosamine. Niacinamide also effectively helps reduce acne and heal wounds. It has anti-oxidant and anti-inflammatory properties. Overall, niacinamide is a compound with many different uses that can increase overall skin health.

Key benefits of Niacinamide in skin care:

  • Treat hyperpigmentation [3] [7] [8]
  • Lightening and brightening [3] [7] [8]
  • Reduce fine lines and wrinkles [9]
  • Anti-inflammatory [5] [6] [8]
  • Anti-oxidant [10] [13]
  • Anti-acne [1] [5] [11]
  • Moisturizing and hydration [2] [5] [12]
  • Restore barrier function [2] [5] [12]
  • Wound healing support [5] [6]
  • Increase skin elasticity [5] [9]
  • Oil/sebum control [2]
  • Pore refinement [2]
  • Sun damage repair [13]
  • Sun damage protection [10]
  • Stimulate collagen production [5]
  • Stimulate HA production [9]
$6.60
Oat Beta Glucan
Oat Beta Glucan (β-glucans) are polysaccharides composed of glucose molecules in long linear polymers and they are naturally present in fungi, plants, algae and bacteria. Glucans interact with immune cells and have immunopharmacological properties. The results of studies showed that beta-glucan, despite its large molecular size may be capable of penetrating deep into the skin and delivering significant benefits for the skin. After the entery to skin, oat beta-glucan forms a thin film above the stratum corneum and epidermis and promotes sustained moisturization properties together with an improved, smoother appearance of the skin. Interaction between glucan and glucan receptors triggers reactions with fibroblasts that stimulate collagen synthesis. As a result of promoted collagen synthesis, elasticity of the skin is enhanced, wrinkle is reduced, with significant reduction of wrinkle depth and height, and overall roughness, aging process is largely delayed, and the negative effect of radiation is minimized. Glucan added to sunscreens helps in preservation of Langerhans cells so it can be use as an excellent photoprotective agent. It has been reported that topical glucans administration can suport wound healing and be useful for scar care by stimulating tissue granulation, collagen deposition, and re-epithelialization. Oat beta glucan also has anti-inflammatory antioxidant and free radicals scavenging capabilities.

 Key benefits of Oat Beta Glucan (Beta 1-3, 1-4) in skin care:

  • anti-inflammatory [1] [4] [5] [9]
  • reduce fine lines and wrinkles [5] [7] [8]
  • wound healing suport [9] [10] [11] [12]
  • moisturizing and hydration [7]
  • increase skin elasticity [5] [7] [8] [9]
  • sun damage protection [12]
  • sun damage repair [5] [9]
  • antioxidant [13] [14]
  • scar care [9] [10]
  • stimulate collagen production [8] [9] [10]

 
$11.10
Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 Liposome Emulsion
The Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 peptides liposome emulsion contains the peptides pal-ghk and pal-gqp acting in synergy to repair the cutaneous damages of age. By activating the skin’s natural production of collagen, elastin and hyaluronic acid, the peptides work to reduce wrinkles and other signs of aging. Collagen, made up of long strands of amino acids, is really the main building block of skin, giving the skin its smooth, and youthful appearance. As we age, collagen is lost, and this gives way to aged, wrinkled looking skin. When the long strands of amino acids in collagen are broken down they create small chains commonly referred to as peptides. The presence of these peptides signal to the skin that it has lost collagen and the production of more is necessary. The peptides Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 work to mimic the appearance of this broken down collagen, causing your skin to react by producing more collagen, as well as elastin (responsible for the skin’s elasticity, and  hyaluronic acid (which plumps up the skin and gives it that healthy, full look).

Key benefits of the peptides Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 liposome emulsion in skin care:

  • reduce fine lines and wrinkles
  • stimulate HA production
  • glycation inhibitor and repair
  • increase skin elasticity
  • moisturizing and hydration
  • stimulate collagen production
  • sun damage repair

BulkActives Peptide Liposome Emulsion

  • Palmitoyl oligopeptide (PAL GHK) 260ppm  
  • Palmitoyl tetrapeptide-7 ppm (PAL GQPR) 140ppm
  • Twice the strength of Matrixyl 3000
$20.70
Based on 10 reviews.
Phytosterol

Phytosterols are a family of plant-produced molecules with diverse health benefits. In cosmetics, the ability to stimulate collagen production is most interesting. Together with antioxidant activity and down-regulation of collagen degrading enzymes, these abilities help repair damage in photoaged skin. Phytosterols also have anti-inflammatory properties, which are useful in UV protection, dermatitis treatment, and even cancer prevention. They are widely used in burn wound care – phytosterols were found to improve healing, improve scar appearance and possess analgesic properties, reducing the need of opiate drugs. Antimicrobial activity of phytosterols is also important in skin care, as it can be utilized in both wound care and general fight against infections, such as Candida. Finally, phytosterols regulate transport of cholesterol and thus sebum production – this may present a good treatment option for acne and other sebum-related conditions.

NOTE: To assist you with solubility issues, we now also sell Phytosterol in a standardized  pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 11% solution gives 1% Phytosterols content in final product.
    32% solution gives 3% Phytosterols content in final product.
    53% solution gives 5% Phytosterols content in final product.

Key benefits of Phytosterols in skin care:

  • Anti-inflammatory [2], [12]–[14]
  • Anti-bacterial [6], [7]
  • Oil/sebum control [8]
  • Anti-acne [8]
  • Sun damage protection [10], [11]
  • Stimulate collagen production [9]–[11]
  • Restore barrier function [5]
  • Matrix metalloproteinase (MMP) inhibitors [9]–[11]
  • Wound healing support [3]–[5]
  • Scar care [3]–[5]
$6.45
Pomegranate (40% Ellagic)
Pomegranates have been used in medicine since ancient times. The extract of this plant contains many compounds acting synergistically to produce strong antioxidant and anti-inflammatory effects. It also helps maintain collagen levels, both by promoting its synthesis and inhibiting collagen-degrading enzymes. Due to these properties, pomegranate extract has a range of benefits in UV protection – it can be used both to prevent and to reduce sunlight damage (photoageing) after exposure. Furthermore, it is an effective skin whitening agent, used to treat melasma and other hyperpigmentation problems. Finally, faster wound healing is observed when using this extract. Combined with antibacterial, antifungal, anti-inflammatory properties and the ability to increase collagen synthesis, this makes pomegranate extract beneficial in many aspects of wound care.

NOTE: To assist you with solubility issues, we now also sell Pomegranate Extract as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 25% solution gives 1% Ellagic Acid content in final product.
  • 75% solution gives 3% Ellagic Acid content in final product.
  • 13% solution gives 1% Polyphenols content in final product.
  • 39% solution gives 3% Polyphenols content in final product.
  • 65% solution gives 5% Polyphenols content in final product.

 Key benefits of Pomegranate extract in skin care:

  • Sun damage protection [4], [7], [8]
  • Sun damage repair [7]–[9]
  • Antioxidant [1]–[4]
  • Glycation inhibitor and repair [3]
  • Anti-bacterial [2], [16]
  • Lightening and brightening [6], [10]–[12]
  • Matrix metalloproteinase (MMP) inhibitors [8], [9]
  • Stimulate collagen production [9]
  • Treat hyperpigmentation [10]–[12]
  • Wound healing support [13]–[16]
  • Anti-inflammatory [6], [8], [15]
$7.30
Sclerotium Gum
Sclerotium gum is an active ingredient obtained through fermentation from hardened fungal masses of various types of fungi. The most common source is a parasitic fungus named Sclerotium rolfsii.  Due to its efficiency as a thickening agent, emulsifier and stabilizer, sclerotium gum is used in numerous applications in the industrial, food and pharmaceutical fields. Recent research showed that sclerotium gum is a compound perfectly suitable for topical delivery of pharmaceuticals and natural active ingredients. Besides providing the right viscosity and stability of the topical preparation, the gum also has multiple benefits for the skin. Sclerotium gum is high in polysaccharides, especially beta glucans, namely scleroglucan, and has multiple benefits for the skin: it protects the lipid barrier, prevents water loss, increases moisturization, protects and repair damaged skin, enhances the local immune response and increases collagen production and deposits.

Key benefits of Sclerotium Gum in skin care:

  • moisturizing and hydration [9][12][13]
  • anti-inflammatory [6] [10]
  • wound healing support [6] [10]
  • sun damage protection [10]
  • sun damage repair [10]
  • stimulate collagen production[11]
  • Anti-bacterial [11]
  • Antioxidant [10]
  • Restore barrier function [9][12][13]
 
  • Emulsion stabilizer
  • Improves flow of emulsions
  • Wide pH tolerance :: 5 to 12
  • Offers a nice feel to products
  • Viscosity not affected by high heat
  • Stable in extreme physical and chemical conditions
  • Creates smooth flowing gels / serums
  • Improves natural moisture levels in skin and hair
  • Gels the water phase for enhanced viscosity without stiffness
  • Outstanding suspending ability
  • Alternative to carbopol and Gelmaker Ultra
  • Moisturizer
$17.00
Sodium Ascorbyl Phosphate (SAP)
Vitamin C, or ascorbic acid, is one of nature’s most powerful antioxidants.As the natural aging process and environmental hazards increase the amount of free radicals in the skin, ascorbic acid and its derivatives can effectively neutralize these damaging agents and prevent further damage.Ascorbic acid has been shown to increase the synthesis of collagen in the skin to reduce the appearance of wrinkles and to block the melanin synthesis pathway, reducing age spots and lightening skin.Unfortunately, ascorbic acid is not stable in aqueous solutions and is quickly degraded.The hydrophilic ascorbic acid derivative sodium ascorbyl phosphate is significantly more shelf-stable in solutions and, as it is converted to ascorbic acid in skin, retains all of the skin-benefitting aspects of vitamin C.Therefore sodium ascorbyl phosphate is the ideal choice for anti-aging emulsion creams.

Key benefits of Sodium Ascorbyl Phosphate in skin care:

  • Anti-acne [7]  [8]
  • Antioxidant [3] [4] [6] [9] [10]
  • Increase skin elasticity [1] [4]
  • Reduce fine lines and wrinkles [1] [4]
  • Stimulate collagen production [1] [4]
  • Sun damage protection [9] [10]
  • Sun damage repair [9] [10]
  • Lightening and brightening [12]
  • Treat hyperpigmentation [12]
$13.30
Soy Isoflavones
Soy isoflavones are comparatively new in regards to cosmetic use, however, studies show they have multiple skin-benefitting properties.Isoflavones are structurally similar to estrogens and can activate estrogen signaling pathways, including collagen synthesis, to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and increase tissue hydration.Additionally isoflavones are powerful antioxidants that can halt and reverse the appearance of aging due to free radicals caused by sunlight and other environmental hazards.As such, soy isoflavones are useful in reducing redness of the skin and decreasing the appearance of dark spots.These properties make soy isoflavones ideal for use in anti-aging, moisturizing, and skin protecting creams.

Key benefits of Soy isoflavones on skin care:

  • Anti-inflammatory [6, 11, 12]
  • Antioxidant [3, 6]
  • Increase skin elasticity [1, 4, 5, 15]
  • Matrix metalloproteinase [MMP] inhibitors [9]
  • Moisturizing and hydration [5, 15]
  • Natural phytoestrogens [3, 15]
  • Reduce fine lines and wrinkles [1, 4, 5, 15]
  • Stimulate collagen production [1, 4, 5, 15]
  • Sun damage protection [3, 6, 11, 12, 14]
  • Sun damage repair [3, 6, 11, 12, 14]
  • Treat hyperpigmentation [3]
$14.20
Vitamin E Natural Mixed Tocopherols
Natural Vitamin E Mixed Tocopherols is an active blend of natural mixed tocopherols containing naturally occurring d-alpha, d-beta, d-gamma and d-delta tocopherols. These are NATURAL tocopherols, they are NOT the synthetic, racemix dl-tocopherol or dl-tocopheryl acetate. 

Tocopherol is the most commonly used form of vitamin E in cosmetic products. α-tocopherol, one of four types of tocopherol, is the most abundant form of vitamin E naturally found in the skin. α and γ forms are excreted in sebum [oil] and act as a barrier for the skin. The amount of tocopherol in the skin decreases over time due to sun exposure. Tocopherols are strong anti-oxidants. Anti-oxidants help protect against skin aging. Tocopherols use their anti-oxidant ability to protect against sun damage and repair sun damage. They increase collagen production and protect existing collagen by inhibiting matrix metalloproteinase [MMP] that degrades collagen. Mixed tocopherols have anti-inflammatory properties and accelerate wound healing.
 

Key benefits of Vitamin E Mixed Tocopherols in skin care:

  • Antioxidant [1-15]
  • Sun damage protection [2, 4, 7, 8, 9, 14, 15]
  • Sun damage repair [12]
  • Anti-inflammatory [2, 5, 10, 14]
  • Wound Healing Support [5]
  • Matrix Metalloproteinase [MMP] inhibitors [11]
  • Stimulate collagen production [5]
  • Reduces fine lines and wrinkles [3]
$26.30
Vitamin E Natural Mixed Tocotrienols
Tocotrienol, a form of vitamin E, is known to be a natural powerful antioxidant that is quickly absorbed into the skin. It reduces damage involved with skin aging that is caused by harmful free radicals from UV light and ozone. Symptoms of skin aging include wrinkles, dryness, hyperpigmentation, and loss of elasticity. Tocotrienol increases collagen synthesis, which improves skin elasticity. It can also “unclog” skin burdened by excessive cholesterol. Toctrienol has anti-inflammatory properties and is able to reduce symptoms of allergic skin reactions. It can also help reduce the drying side effects of acne regimens such as benzoyl peroxide.

Natural Vitamin E Mixed Tocotrienols is an active blend of natural alpha tocopherol and alpha tocotrienol, beta tocotrienol, delta tocotrienol, and gamma tocotrienol.These are NATURAL tocotrienols, they are NOT synthetic.

Key Benefits of Vitamin E mixed Tocotrienols in skin care:

  • Antioxidant [1-10]
  • Sun damage protection [1, 3, 4, 5, 6, 7, 10]
  • Sun damage repair [1, 3, 4, 5, 6, 7, 8, 9, 10]
  • Anti-inflammatory [4, 6, 9]
  • Stimulate collagen production [1, 2, 3]
  • Increase skin elasticity [2, 3]
  • Restore barrier function [8]
  • Treat hyperpigmentation [11]
$26.30
Magnesium Ascorbyl Phosphate (MAP)
Magnesium Ascorbyl  Phosphate (MAP) is a water soluble magnesium salt of  ascorbic acid. It is very stable, has great bioavailability and a neutral PH. On the skin, MAP has beneficial effects – similar to vitamin C: antioxidant, anti-inflammatory, boosts skin elasticity, lightening, hydrating, and wound healing, photo-protective. MAP is also easy to use and incorporate in DIY formulation both in aqueous and oil in water emulsions.


Key benefits of Magnesium Ascorbyl Phosphate (MAP) in skin care:

  • Antioxidant [3-15]
  • Increase skin elasticity [5] [11]
  • Stimulate collagen production [5] [11]
  • Sun damage protection [9] [10] [11]
  • Sun damage repair [9] [10] [11]
  • Lightening and brightening [12] [13] [14][15]
  • Treat hyperpigmentation [12] [13] [14][15]
$10.60
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