Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
I ordered the 50 gm after being very pleased with the smaller size. Although it's pricey the quality is outstanding. This is the safest way to add Vit C to your formulations as it's not nearly as fussy as the powder. I've made both serums and creams with this product and have been very pleased with the outcomes! Highly recommend!.. ...»
This lovely, simple, and affordable product has become something I don't want to be without. I am 47, with very sensitive and reactive dry skin. This cream doesn't feel particularly moisturizing and leaves something of a 'dry' finish on the skin after application, but it's had SUCH a positive impact on my face. The redness and papules from my rosacea and seb derm have reduced by a good 90%. It's been a magical barrier restorer and I panicked when it was temporarily out of stock. I would recomme.. ...»
This is the best product I have ever used on my skin and I tried a LOT of expansive brands. It helps with redness and overall skin tone. Please do not ever stop making this stuff... ...»
I am 69 and I have used this product for two years almost every day at a high dose, adding it to my antioxidant day cream, with excellent results. For me it has a very high quality and effectiveness: reduction of wrinkles, hydrated skin, unified color without blemishes ... A product of 10, the same score that I give to John for the quality of the products he sells, his excellent description / use and the bibliographic contribution.En .. ...»
Any long delivery delays are caused by The Canada Border Services Agency.
I now ONLY offer EMS as a shipping option to Canada.
This appears to have resolved most of the delays caused by The Canada Border Services Agency.
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We sell COSMETIC RAW MATERIALS, which are meant to be used at an appropriate percentage in a cosmetic formulation of your devising. Please do not order our products unless you know how to formulate creams and lotions with it!
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Acne, or the appearance of inflamed red bumps on the skin which may release pus [commonly referred to as pimples], is the most common dermatologic condition, affecting approximately 85% of teenagers between fifteen and seventeen years old (1). For many people however, this condition may persist for many years after this time period, particularly for menopausal women (2). Acne results most commonly due to excessive accumulation of sebum, an oily secretion from sebaceous glands, beneath the skin. Generally, sebum is secreted to the skin surface through the hair follicle, a process which is hormonally regulated. During puberty, the increase in hormones causes a coinciding increase in sebum production and can lead to a blockage of the hair follicles (3-5). Separately, it is believed that genetic disposition to sebum overproduction or genetic hormonal imbalances can also cause or contribute to acne (6). Oxidation of the sebum within the clogged hair follicle stimulates the sebaceous gland to initiate an inflammatory response. Further, matrix metalloproteinases present within the sebum contribute to the pro-inflammatory signaling and also degrade the extracellular matrix (7). Together these attributes contribute to the redness and discomfort associated with a pimple. The environment created by the clogging of a hair follicle with sebum is prime realty for bacteria. The most commonly found species of bacteria at clogged sites is Propionibacterium acnes. While it is believed that the presence of these bacteria contributes to the pro-inflammatory immune response that was already initiated, if or how P. acnes directly causes acne remains unclear (8).
There are several types of approaches currently used to treat acne. Most importantly is to remove the sebum which clogs pores and is the most common root cause of pimples. Exfoliation is recommended to help remove dead skin which can contribute to sebum entrapment. Use of topical ointments containing anti-inflammatory agents are recommended to alleviate the inflammation associated with acne. For more information on anti-inflammatory agents, see our link here: https://www.bulkactives.com/actives/natural-anti-inflammatory-skin-care-ingredients. Finally, antibacterial agents are recommended to reduce P. acnes infections (3). Despite the fact that little is known about if/how bacteria contribute to acne, multiple studies have found that antibacterial agents are effective at reducing symptoms of acne; the fact that many antibacterial agents also reduce inflammation may be a prominent reason for their success (7).
Many natural compounds have been shown to have intrinsic anti-bacterial and anti-inflammatory properties. Oil extracted from African baobab trees has been shown to be a potent anti-microbial agent and anti-inflammatory agent. Most importantly, baobab oils can reduce sebum production in skin. Because of the high fatty acid content baobab oil is an excellent moisturizer which can efficiently penetrate the skin (9-11). Extracts from the boswellia tree [boswelic acid] can inhibit growth of both aerobic and anaerobic bacterial species [including P. acnes] and can inhibit production of the pro-inflammatory mediators leukotrienes (12, 13). Resveratrol, an active extracted from grape skins, is a phytoestrogen and can therefore improve the skin in many ways. Resveratrol acts to fight acne directly by decreasing proliferation rates of sebaceous gland cells, inhibiting growth of P. acnes, and on human volunteers has been shown to decrease the number of acne lesions in a split-face system (14-16). Resveratrol can also reduce redness and edema and attenuate the immune response (17, 18). The fact that it is a phytoestrogen makes this compound specifically useful for menopausal and post-menopausal women (17).
Salicylic acid, thanks to its lipophilicity, can efficiently penetrate skin and exfoliate dead skin while removing excess sebum. Multiple clinical studies have demonstrated salicylic acid decreases clogging of hair follicles and decreases the number of inflamed acne lesions [6-8]. Sialicin, a derivative of siacylic acid which is extracted from white willow bark, is not only efficient at exfoliating and decreasing sebum in follicles, but it also is a potent anti-inflammatory agent, inhibitor of the matrix metalloproteinases in sebum which contribute to tissue breakdown, and antibacterial agent (19-21). Importantly, no side effects are associated with topical use of sialicin (19).
Carnitine, a compound required by the body for fat metabolism, reduces sebum levels in the skin and can inhibit sebum synthesis. Clinical studies have demonstrated that carnitine is effective at significantly reducing lipid and sebum levels within sebaceous glands. Carnitine also decreased levels of P. acnes within facial lesions in trial participants and the total number of pimples was decreased five-fold (22, 23). D-panthenol, or provitamin B5, can effectively reduce inflammation and erythema and can therefore reduce the indications of acne. Additionally, D-panthenol can decrease sebum in the skin and has been used successfully in the clinic to decrease number of acne lesions by treating the disease at the root cause (24, 25). As an added benefit, D-panthenol can also reduce the appearance of acne-induced scars after the lesions have resolved (26). Niacinamide, also known as water-soluble vitamin B3, has been demonstrated clinically to reduce facial redness, improve barrier function, and reduce infiltration of immune cells which drive inflammation (27, 28). Topical application has been used to reduce acne lesions and has been shown to be comparable to current therapeutic approaches such as clindamycin. Due to increasing incidences of bacterial resistance to clindamycin niacinamide may be a better approach for treatment of acne (14). Sodium ascorbyl phosphate, or vitamin C, also is a known anti-bacterial agent which significantly outperformed a leading acne treatment in a clinical trial (29).
References
[1] Krowchuk DP. Managing Adolescent Acne. Pediatrics in review. 2005;26(7):251.
[2] Kligman A. Postmenopausal acne. Cutis. 1991;47(6):425-6.
[3] Mashkevich G. Cosmetic Dermatology: Principles & Practice, Leslie Baumann, MD. Facial plastic surgery. 2010;26(01):059-.
[4] Zouboulis CC. Acne and sebaceous gland function. Clinics in dermatology. 2004;22(5):360-6.
[5] Thiboutot D. Acne: hormonal concepts and therapy. Clinics in dermatology. 2004;22(5):419-28.
[6] Bhate K, Williams HC. Epidemiology of acne vulgaris. British Journal of Dermatology. 2013;168(3):474-85.
[7] Williams HC, Dellavalle RP, Garner S. Acne vulgaris. The Lancet.379(9813):361-72.
[8] Bojar RA, Holland KT. Acne and propionibacterium acnes. Clinics in Dermatology. 2004;22(5):375-9.
[9] Kamatou G, Vermaak I, Viljoen A. An updated review of Adansonia digitata: A commercially important African tree. South African Journal of Botany. 2011;77(4):908-19.
[10] Vermaak I, Kamatou G, Komane-Mofokeng B, Viljoen A, Beckett K. African seed oils of commercial importance—cosmetic applications. South African Journal of Botany. 2011;77(4):920-33.
[11] Zimba N, Wren S, Stucki A. Three major tree nut oils of southern central Africa: their uses and future as commercial base oils. International Journal of Aromatherapy. 2005;15(4):177-82.
[12] Siddiqui M. Boswellia serrata, a potential antiinflammatory agent: an overview. Indian journal of pharmaceutical sciences. 2011;73(3):255.
[13] Weckesser S, Engel K, Simon-Haarhaus B, Wittmer A, Pelz K, Schempp C. Screening of plant extracts for antimicrobial activity against bacteria and yeasts with dermatological relevance. Phytomedicine. 2007;14(7):508-16.
[14] Shalita AR, Smith JG, Parish LC, Sofman MS, Chalker DK. Topical Nicotinamide Compared with Clindamycin Gel in the Treatment of Inelammatory Acne Vulgaris. International journal of dermatology. 1995;34(6):434-7.
[15] Taylor EJ, Yu Y, Champer J, Kim J. Resveratrol Demonstrates Antimicrobial Effects Against Propionibacterium acnes In Vitro. Dermatology and therapy. 2014;4(2):249-57.
[16] Kim SY, Hyun MY, Go KC, Zouboulis CC, Kim BJ. Resveratrol exerts growth inhibitory effects on human SZ95 sebocytes through the inactivation of the PI3-K/Akt pathway. International journal of molecular medicine. 2015;35(4):1042-50.
[17] Jackson RL, Greiwe JS, Schwen RJ. Ageing skin: oestrogen receptor β agonists offer an approach to change the outcome. Experimental dermatology. 2011;20(11):879-82.
[18] Nwachukwu JC, Srinivasan S, Bruno NE, Parent AA, Hughes TS, Pollock JA, et al. Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network. Elife. 2014;3:e02057.
[19] Levy LL, Emer JJ. Emotional benefit of cosmetic camouflage in the treatment of facial skin conditions: personal experience and review. Clinical, cosmetic and investigational dermatology. 2012;5:173.
[20] Gopaul R, Knaggs H, Lephart J. Salicin regulates the expression of functional ‘youth gene clusters’ to reflect a more youthful gene expression profile. International journal of cosmetic science. 2011;33(5):416-20.
[21] Khayyal MT, El-Ghazaly MA, Abdallah DM, Okpanyi SN, Kelber O, Weiser D. Mechanisms involved in the anti-inflammatory effect of a standardized willow bark extract. Arzneimittel-Forschung. 2004;55(11):677-87.
[22] Peirano RI, Hamann T, Düsing HJ, Akhiani M, Koop U, Schmidt‐Rose T, et al. Topically applied l‐carnitine effectively reduces sebum secretion in human skin. Journal of cosmetic dermatology. 2012;11(1):30-6.
[23] Angelova‐Fischer I, Rippke F, Fischer T, Neufang G, Zillikens D. A double‐blind, randomized, vehicle‐controlled efficacy assessment study of a skin care formulation for improvement of mild to moderately severe acne. Journal of the European Academy of Dermatology and Venereology. 2013;27(s2):6-11.
[24] Baschong W, Hüglin D, Röding J. D-panthenol loaded nanotopes< TM> providing enhanced anti-inflammatory efficacy: A study on human volunteers. SÖFW-journal. 1999;125(4):18-20.
[25] Rudolph C, TAUSCHEL H-D. Untersuchungen zur perkutanen Wirksamkeit einer Heparin-Allantoin-Dexpanthenol-Kombination in spezieller Salbengrundlage: Antiallergische/antiinflammatorische Wirkung im PCA-test bei der Ratte. Arzneimittel-Forschung. 1984;34(12):1766-8.
[26] Leung L. Pantothenic acid deficiency as the pathogenesis of acne vulgaris. Medical hypotheses. 1995;44(6):490-2.
[27] Gehring W. Nicotinic acid/niacinamide and the skin. Journal of cosmetic dermatology. 2004;3(2):88-93.
[28] Soma Y, Kashima M, Imaizumi A, Takahama H, Kawakami T, Mizoguchi M. Moisturizing effects of topical nicotinamide on atopic dry skin. International journal of dermatology. 2005;44(3):197-202.
[29] Woolery‐Lloyd H, Baumann L, Ikeno H. Sodium L‐ascorbyl‐2‐phosphate 5% lotion for the treatment of acne vulgaris: a randomized, double‐blind, controlled trial. Journal of cosmetic dermatology. 2010;9(1):22-7.
EcoFriendly, sustainable, synthetic Alpha Bisabolol , which offers all the benefits of natural Alpha Bisabolol, is now available.
For thousands of years, chamomile has been a prized component of many ancient therapies. The active ingredient of chamomile, α-bisabolol, is a lightly floral-scented essential oil extracted from the Candeia tree, a tropical relative of cammomile, in modern times. In order to produce 100 tons of α-bisabolol, 850 hectares of timber must be harvested . Due to deforestation amid a global high demand, synthetic sources of α-bisabolol are now available. New generations of the synthetic compound offer 85% α-bisabolol content and all of the benefits of the natural product. Easily absorbed by the skin, α-bisabolol is a potent anti-microbial agent, anti-inflammatory, and potent wound-care agent. It has valuable applications in soaps, lotions, soothing face creams, and wound-healing products
Key benefits of Sustainable Alpha Bisabolol in skin care:
Ascorbyl tetraisopalmitate (Tetrahexyldecyl Ascorbate) is a molecule derived from vitamin C and isopalmitic acid. Pure vitamin C has several drawbacks for cosmeceutical use, most important of which is the low stability. Chemically modified vitamin molecules are more stable, and pure vitamin is released from the derivatives inside the body. Therefore, the effects of Ascorbyl Tetraisopalmitate are similar to those of vitamin C, most importantly it is able to act as an antioxidant. Ascorbyl tetraisopalmitate reduces the production of oxidizing agents, which contribute to cell damage after exposure to UV or chemical hazards. This effect is even stronger in the modified molecule than in pure vitamin C. Additionally, Ascorbyl Tetraisopalmitate protects against DNA damage and skin darkening caused by UV exposure. Finally, skin visual appearance is also improved by Ascorbyl tetraisopalmitate, as it promotes collagen synthesis and acts as a hydrating agent in reducing skin roughness.
Key benefits of Ascorbyl tetraisopalmitate in skin care:
Resin from the Boswella serrata tree found in parts of Asia and Africa is commonly used in traditional Ayurvedic medicine for a variety of disorders associated with inflammation. It has been used medicinally for centuries and is now gaining support through research. The main ingredients of the resin are boswellic acids. Boswellic acids have anti-inflammatory effects when applied topically. Preparations using either the resin or pure boswellic acid extracted from the resin can help treat inflammatory disorders such as osteoarthritis, eczema, and psoriasis. The extract helps reduce sun damage, fine lines, and acne. It stimulates collagen production. Also, it aids in wound healing and inhibits tumor growth. Research shows boswella serrata extract has a variety of useful anti-inflammatory effects and can help alleviate the symptoms of a variety of conditions. This extract has been popularized as Boswelox™ by L’Oreal and its Wrinkle-de-crease.
NOTE: To assist you with solubility issues, we now also sell Boswellia serrata (Boswelic acid) as a liquid standardized pre-dissolved solution. Just add the liquid to your cream and mix well.
16% solution gives 1% Boswelic Acid content in final product.
46% solution gives 3% Boswelic Acid content in final product.
66% solution gives 5% Boswelic Acid content in final product.
Niacinamide, also known as nicotinamide, is a water soluble form of vitamin B3. Vitamin B3 is essential for maintaining skin health. Niacinamide increases production of important skin structural components such as collagen, ceramide, and keratin. This helps increase moisture and strengthen skin. Niacinamide is known to decrease hyperpigmentation, effectively lightening and brightening skin, especially when used together with n-acetyl glucosamine, a hyaluronic acid precursor. It reduces wrinkles and again, this effect is better with n-acetyl glucosamine. Niacinamide also effectively helps reduce acne and heal wounds. It has anti-oxidant and anti-inflammatory properties. Overall, niacinamide is a compound with many different uses that can increase overall skin health.
Resveratrol is a compound found in grapes and many other plants. It is currently investigated in many skincare applications. Resveratrol protects cells from oxidative stress – it is an antioxidant itself, and activates the synthesis of other such compounds. It also regulates inflammatory responses and even aids the distribution of cosmetical sunscreens, thus helping to prevent UV damage to the skin. Similarities in structure allow resveratrol to replace estrogen in post-menopausal women, helping to reduce collagen loss and reduce skin ageing symptoms. Additionally, it counters photoageing by inhibiting melanin synthesis, resulting in lighter skin and less pigmented spots. Even acne can be alleviated by applying resveratrol, as it has antibacterial properties and controls sebaceous cell growth. Finally, it is a promising agent in melanoma prevention, able to delay the emergence and reduce the size of skin tumors.
NOTE:To assist you with solubility issues, we now also sell Resveratrol in a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.
Salicylic acid is a hydroxyl acid compound originally derived from willow tree bark. It has many useful effects on skin, the most prominent being its use as an anti-acne treatment. It penetrates deep into pores, removing trapped oil that can cause blemishes. Salicylic acid is a keratolytic compound, meaning it exfoliates the skin and sloughs off dead skin cells, leaving smooth skin. This makes it useful for treating scaly skin, as well as calluses and warts. It also has anti-inflammatory and anti-bacterial properties. Salicylic acid has been shown to influence photodamage by reducing hyperpigmentation and providing protection against UV exposure.
NEW: We are excited to announce that we now also sell a WATER-SOLUBLE salicylic acid powder (assay 50%)!
Build effective Salicylic Acid formulations free from alcohol, discoloration, and recrystallization. WATER SOLUBLE salicylic acid increases water solubility of Salicylic Acid from 0.2% to 5%, and results in a pH of about 4. No need for organic solvents.
For higher strength formulations we also have Salicylic Acid (Beta Hydroxy Acid) as a pre-dissolved solution. Just add the liquid to your cream and mix well.
6.7% solution gives 1% Salicylic acid content in final product.
13.3% solution gives 2% Salicylic acid content in final product.
20% solution gives 3% Salicylic acid content in final product.
26.7% solution gives 4% Salicylic acid content in final product.
33.3% solution gives 5% Salicylic acid content in final product.
Vitamin C, or ascorbic acid, is one of nature’s most powerful antioxidants.As the natural aging process and environmental hazards increase the amount of free radicals in the skin, ascorbic acid and its derivatives can effectively neutralize these damaging agents and prevent further damage.Ascorbic acid has been shown to increase the synthesis of collagen in the skin to reduce the appearance of wrinkles and to block the melanin synthesis pathway, reducing age spots and lightening skin.Unfortunately, ascorbic acid is not stable in aqueous solutions and is quickly degraded.The hydrophilic ascorbic acid derivative sodium ascorbyl phosphate is significantly more shelf-stable in solutions and, as it is converted to ascorbic acid in skin, retains all of the skin-benefitting aspects of vitamin C.Therefore sodium ascorbyl phosphate is the ideal choice for anti-aging emulsion creams.
Key benefits of Sodium Ascorbyl Phosphate in skin care:
White willow bark extract has been used by many cultures to reduce pain and inflammation. It contains salicin, a natural form of salicylic acid known to have anti-inflammatory effects. Salicin can reduce signs of aging by reducing the appearance of pores, wrinkles, and pigmentation. It also softens and moisturizes the skin. Salicin contributes to white willow bark extract’s exfoliating and acne-reducing power. White willow bark extract also contains polyphenols that contribute anti-oxidant and anti-inflammatory effects. These can help protect against sun damage and premature aging when used with sunscreen. White willow bark extract is a natural alternative to salicylic acid that has additional properties to enhance skin health.
NOTE: To assist you with solubility issues, we now also sell White Willow bark extract as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.
Key benefits of White Willow bark (salicin) in skin care:
Magnesium Ascorbyl Phosphate (MAP) is a water soluble magnesium salt of ascorbic acid. It is very stable, has great bioavailability and a neutral PH. On the skin, MAP has beneficial effects – similar to vitamin C: antioxidant, anti-inflammatory, boosts skin elasticity, lightening, hydrating, and wound healing, photo-protective. MAP is also easy to use and incorporate in DIY formulation both in aqueous and oil in water emulsions.
Key benefits of Magnesium Ascorbyl Phosphate (MAP) in skin care:
BulkActives are DIY skin care suppliers of skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and standardized botanical extracts for diy skin care products and homemade cosmetics.
DISCLAIMER
We do NOT sell ready-made skin care products!
All our products are powders, liquids, flakes or gels, used for making your own skin care products.
All our products are cosmetic / technical grade only.
We do NOT sell pharmaceuticals, prescription drugs or nutritional supplements.
Any statements about our products have not been evaluated by the FDA.
Our active skin care ingredients are not intended to diagnose, treat, cure, or prevent any disease
SHIPPING
Please write your correct address:
We take NO responsibility for delivery issues caused by customers entering the wrong address in the checkout page
Delivery
BulkActives is a part-time business. Orders are processed and mailed on Saturdays.
Canadian Customers:
Any long delivery delays are caused by The Canada Border Services Agency.
I now ONLY offer EMS as a shipping option to Canada.
This appears to have resolved most of the delays caused by The Canada Border Services Agency.