wound healing support

Boswellia serrata (Boswelic acid)

Resin from the Boswella serrata tree found in parts of Asia and Africa is commonly used in traditional Ayurvedic medicine for a variety of disorders associated with inflammation. It has been used medicinally for centuries and is now gaining support through research. The main ingredients of the resin are boswellic acids. Boswellic acids have anti-inflammatory effects when applied topically. Preparations using either the resin or pure boswellic acid extracted from the resin can help treat inflammatory disorders such as osteoarthritis, eczema, and psoriasis. The extract helps reduce sun damage, fine lines, and acne. It stimulates collagen production. Also, it aids in wound healing and inhibits tumor growth. Research shows boswella serrata extract has a variety of useful anti-inflammatory effects and can help alleviate the symptoms of a variety of conditions. This extract has been popularized as Boswelox™ by L’Oreal and its Wrinkle-de-crease.

NOTE: To assist you with solubility issues, we now also sell Boswellia serrata (Boswelic acid) as a liquid standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

16% solution gives 1% Boswelic Acid content in final product.
46% solution gives 3% Boswelic Acid content in final product.
66% solution gives 5% Boswelic Acid content in final product.

Key benefits of Boswellia serrata in skin care:

Anti-inflammatory ^{[1] [2] [3] [4] [5] [6] [7] [8] [9] [10]}
Sun damage repair^{[1] [5]}
Stimulate collagen production ^[1]
Reduce fine lines ^{[1] [5]}
Anti-bacterial ^[10]
Anti-acne ^[10]
Tumor inhibition^[3]
Wound healing support^[4]

$7.75

Centella asiatica (Gotu Kola)

Centella asiatica is a tropical plant that has been used extensively in Indian medicine. It has diverse applications for skin cosmetics: firstly, it is effective in wound care, as it promotes healing of simple, infected, non-healing, or burn wounds, as well as wounds in patients with diabetes, undergoing radiotherapy or steroid medication. Centella is also used for treating scars and preventing or reducing stretch marks. The extract of this plant promotes synthesis of collagen, hydroxyproline, hyaluronic acid and cell growth factors, thus helping to maintain the elasticity, strength and general appearance of healthy skin. It also protects the skin from ageing damage, such as glycation, and UV damage, likely by activating antioxidant synthesis.

NOTE: To assist you with solubility issues, we now also sell Centella asiatica as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

15% solution gives 1% triterpenes content in final product.
43% solution gives 3% triterpenes content in final product.
72% solution gives 5% triterpenes content in final product.

Key benefits of Centella asiatica in skin care:

Wound healing support^{[1] [2] [4] [5] [8]}
Stimulate HA production^[2]
Stimulate collagen production ^{[2] [4] [5] [7]}
reduce fine lines and wrinkles ^{[2] [4] [5] [7]}
Increase skin elasticity^[2]
Glycation inhibitor and repair ^[9]
Scar care ^{[2] [4] [12]}
Sun damage protection^[9]

$37.80

Coenzyme Q10 is a molecule naturally involved in energy metabolism in all human cells. Among its many benefits, the antioxidant properties are the most researched. This molecule can prevent oxidation damage to water-insoluble molecules, DNA mutations, collagen synthesis decrease, pigmentation, inflammation and other adverse effects associated with UV exposure and ageing. In combination with vitamin E or other antioxidants, an exceedingly strong antioxidative effect can be achieved. Furthermore, coenzyme Q10 has a unique capability to protect against infrared A radiation, which is also found in sunlight. The promotion of collagen synthesis makes this coenzyme useful in treating ageing-associated skin changes, such as wrinkle appearance. Finally, its anti-inflammatory effect is beneficial not only for UV-damaged skin, but also for wound healing support.

NOTE: To assist you with solubility issues, we now also sell CoQ10 (Coenzyme Q10) as a liquid standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

Key benefits of Coenzyme Q10 in skin care:

Sun damage protection ^{[5] [7] [9]}
Antioxidant^{[1] [3] [4] [5] [6] [7] [8]}
Increase cellular energy production ^[15]
Stimulate collagen production^{[5] [8] [10] [13]}
Lightening & brightening ^[10]
Sun damage repair^{[5] [7] [8]}
Reduce fine lines & wrinkles ^{[5] [11]}
Wound healing support ^[13]
Anti-inflammatory^{[6] [10] [12] [13]}

$17.20

Green tea has numerous benefits in almost all aspects of skin care. The main active ingredient, EGCG, is a potent antioxidant, and protects skin from UV damage. This results in reduced wrinkling, increased collagen content, smoother skin, thicker and more elastic epidermis and other visual benefits. Green tea also helps to moisturize the skin and improves the long-term barrier capabilities. Among the numerous clinical benefits are antibacterial and antifungal effects, which make green tea useful in wound care. Most important health effect is the prevention of melanoma and other types of skin cancer, resulting partly from the EGCG capability to neutralize free radicals and activate DNA repair. Since the extract also reduces inflammation and sebum secretion, it is an effective treatment against acne. Finally, green tea has also been proven to reduce hair loss and follicle death. Active ingredient in Teamine™ and ReVive™ lines.

NOTE: To assist you with solubility issues, we now also sell Green Tea EGCG in a standardized, pre-dissolved solution. Just add the liquid to your cream and mix well.

11% solution gives 1% EGCG content in final product.
33% solution gives 3% EGCG content in final product.
54% solution gives 5% EGCG content in final product.

Key benefits of Green Tea EGCG in skin care:

Sun damage protection^{[1] [2] [3] [4] [5]}
Sun damage repair ^{[1] [2] [3]}
Antioxidant ^{[1] [2] [3] [7]}
Capillary health ^[19]
Moisturizing & hydration ^{[8] [9] [11]}
Reduce fine lines and wrinkles ^{[10] [11]}
Wound healing support ^{[17] [18]}
Oil/sebum control ^[12]
Lightening & brightening^[6]
Restore barrier function ^{[8] [9]}
Anti-inflammatory ^[1]
Anti-acne ^{[12] [13]}
Anti-bacterial ^{[13] [14] [16]}

$17.05

Hyaluronic Acid (sodium hyaluronate powder)

Hyaluronic acid [HA] is a fundamental element of the extracellular matrix. Due to its amazing capacity to retain water, HA is a highly desirable ingredient in moisturizing creams. Further, because HA can stimulate dermal fibroblast proliferation and migration, it is also ideal for use in wrinkle-reducing and anti-aging formulas. HA can be purchased at various molecular weights with different molecular weights eliciting different effects on the skin. For use in wound-healing support or restoring barrier function, high molecular weight is the best option. For the best results in anti-aging and moisturizing creams, low molecular weight HA is the ideal choice due to increased penetration of the HA through the skin. Warning: Customers in countries with a dry climate may find that hyaluronic acid has a drying effect, instead of moisturizing. It is theorized that this is due to the HA drawing moisturize away from the skin.

Key benefits of Hyaluronic acid in skin care:

Moisturizing and hydration ^{[2] [6] [7]}
Reduce fine lines and wrinkles ^{[2] [7] [8]}
Increase skin elasticity ^{[2] [4] [7]}
Wound healing support^{[1] [10] [11]}
Restoring barrier function^[9]

$12.90

Hyaluronic Acid 50 kDa (Low Molecular Weight sodium hyaluronate)

Hyaluronic acid [HA] is an important component of the extracellular matrix. Known to have a role in stimulating dermal fibroblast migration and proliferation as well as for tissue hydration, topical HA has been used in cosmetic applications for decades. Its skin-benefitting properties along with its ability to bind and retain huge amounts of water makes HA ideal for use in anti-wrinkle, anti-aging, and moisturizing creams. HA can exist across a wide range of molecular weights, with the cellular and physiological effects directly depending on the molecular weight of HA present. Therefore, the selection of HA species for use in such creams is of critical importance. High molecular weight HA does not penetrate the epithelium. Very low molecular weight HA, which does penetrate the skin efficiently, can induce a pro-inflammatory response. Recent data indicates that solutions of low molecular weight HA [50 kDa] are best suited for topical use in skin care products as it can penetrate into the skin well but does not cause inflammation. Note: Hyaluronic Acid 50 kDa does not create a thick gel, for this reason we have started selling Sclerotium Gum, the combination of the two ingredients will create an excellent, safe, and efficient product. Warning: Customers in countries with a dry climate may find that hyaluronic acid has a drying effect, instead of moisturizing. It is theorized that this is due to the HA drawing moisturize away from the skin.

Key benefits of Hyaluronic Acid 50 kDa (Low Molecular Weight sodium hyaluronate) in skin care:

Moisturizing and hydration ^{[2] [3] [4]}
Reduce fine lines and wrinkles ^{[2] [4] [6]}
Increase skin elasticity ^{[2] [4] [6]}
Wound healing support ^{[3] [7]}

$13.50

Niacinamide (Vitamin B3)

Niacinamide, also known as nicotinamide, is a water soluble form of vitamin B3. Vitamin B3 is essential for maintaining skin health. Niacinamide increases production of important skin structural components such as collagen, ceramide, and keratin. This helps increase moisture and strengthen skin. Niacinamide is known to decrease hyperpigmentation, effectively lightening and brightening skin, especially when used together with n-acetyl glucosamine, a hyaluronic acid precursor. It reduces wrinkles and again, this effect is better with n-acetyl glucosamine. Niacinamide also effectively helps reduce acne and heal wounds. It has anti-oxidant and anti-inflammatory properties. Overall, niacinamide is a compound with many different uses that can increase overall skin health.

Key benefits of Niacinamide in skin care:

Treat hyperpigmentation ^{[3] [7] [8]}
Lightening and brightening ^{[3] [7] [8]}
Reduce fine lines and wrinkles ^[9]
Anti-inflammatory ^{[5] [6] [8]}
Anti-oxidant ^{[10] [13]}
Anti-acne ^{[1] [5] [11]}
Moisturizing and hydration^{[2] [5] [12]}
Restore barrier function ^{[2] [5] [12]}
Wound healing support ^{[5] [6]}
Increase skin elasticity ^{[5] [9]}
Oil/sebum control^[2]
Pore refinement ^[2]
Sun damage repair ^[13]
Sun damage protection ^[10]
Stimulate collagen production ^[5]
Stimulate HA production^[9]

$6.60

Oat Beta Glucan (β-glucans) are polysaccharides composed of glucose molecules in long linear polymers and they are naturally present in fungi, plants, algae and bacteria. Glucans interact with immune cells and have immunopharmacological properties. The results of studies showed that beta-glucan, despite its large molecular size may be capable of penetrating deep into the skin and delivering significant benefits for the skin. After the entery to skin, oat beta-glucan forms a thin film above the stratum corneum and epidermis and promotes sustained moisturization properties together with an improved, smoother appearance of the skin. Interaction between glucan and glucan receptors triggers reactions with fibroblasts that stimulate collagen synthesis. As a result of promoted collagen synthesis, elasticity of the skin is enhanced, wrinkle is reduced, with significant reduction of wrinkle depth and height, and overall roughness, aging process is largely delayed, and the negative effect of radiation is minimized. Glucan added to sunscreens helps in preservation of Langerhans cells so it can be use as an excellent photoprotective agent. It has been reported that topical glucans administration can suport wound healing and be useful for scar care by stimulating tissue granulation, collagen deposition, and re-epithelialization. Oat beta glucan also has anti-inflammatory antioxidant and free radicals scavenging capabilities.

Key benefits of Oat Beta Glucan (Beta 1-3, 1-4) in skin care:

anti-inflammatory ^{[1] [4] [5] [9]}
reduce fine lines and wrinkles ^{[5] [7] [8]}
wound healing suport ^{[9] [10] [11] [12]}
moisturizing and hydration^[7]
increase skin elasticity^{[5] [7] [8] [9]}
sun damage protection ^[12]
sun damage repair^{[5] [9]}
antioxidant ^{[13] [14]}
scar care ^{[9] [10]}
stimulate collagen production^{[8] [9] [10]}

$11.10

Phytosterols are a family of plant-produced molecules with diverse health benefits. In cosmetics, the ability to stimulate collagen production is most interesting. Together with antioxidant activity and down-regulation of collagen degrading enzymes, these abilities help repair damage in photoaged skin. Phytosterols also have anti-inflammatory properties, which are useful in UV protection, dermatitis treatment, and even cancer prevention. They are widely used in burn wound care – phytosterols were found to improve healing, improve scar appearance and possess analgesic properties, reducing the need of opiate drugs. Antimicrobial activity of phytosterols is also important in skin care, as it can be utilized in both wound care and general fight against infections, such as Candida. Finally, phytosterols regulate transport of cholesterol and thus sebum production – this may present a good treatment option for acne and other sebum-related conditions.

NOTE: To assist you with solubility issues, we now also sell Phytosterol in a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

11% solution gives 1% Phytosterols content in final product.
32% solution gives 3% Phytosterols content in final product.
53% solution gives 5% Phytosterols content in final product.

Key benefits of Phytosterols in skin care:

Anti-inflammatory [2], [12]–[14]
Anti-bacterial [6], [7]
Oil/sebum control [8]
Anti-acne [8]
Sun damage protection [10], [11]
Stimulate collagen production [9]–[11]
Restore barrier function [5]
Matrix metalloproteinase (MMP) inhibitors [9]–[11]
Wound healing support [3]–[5]
Scar care [3]–[5]

$6.45

Sclerotium gum is an active ingredient obtained through fermentation from hardened fungal masses of various types of fungi. The most common source is a parasitic fungus named Sclerotium rolfsii. Due to its efficiency as a thickening agent, emulsifier and stabilizer, sclerotium gum is used in numerous applications in the industrial, food and pharmaceutical fields. Recent research showed that sclerotium gum is a compound perfectly suitable for topical delivery of pharmaceuticals and natural active ingredients. Besides providing the right viscosity and stability of the topical preparation, the gum also has multiple benefits for the skin. Sclerotium gum is high in polysaccharides, especially beta glucans, namely scleroglucan, and has multiple benefits for the skin: it protects the lipid barrier, prevents water loss, increases moisturization, protects and repair damaged skin, enhances the local immune response and increases collagen production and deposits.

Key benefits of Sclerotium Gum in skin care:

moisturizing and hydration [9][12][13]
anti-inflammatory [6] [10]
wound healing support [6] [10]
sun damage protection [10]
sun damage repair [10]
stimulate collagen production[11]
Anti-bacterial [11]
Antioxidant [10]
Restore barrier function [9][12][13]

Emulsion stabilizer
Improves flow of emulsions
Wide pH tolerance :: 5 to 12
Offers a nice feel to products
Viscosity not affected by high heat
Stable in extreme physical and chemical conditions
Creates smooth flowing gels / serums
Improves natural moisture levels in skin and hair
Gels the water phase for enhanced viscosity without stiffness
Outstanding suspending ability
Alternative to carbopol and Gelmaker Ultra
Moisturizer

$17.00

Vitamin E Natural Mixed Tocopherols

Natural Vitamin E Mixed Tocopherols is an active blend of natural mixed tocopherols containing naturally occurring d-alpha, d-beta, d-gamma and d-delta tocopherols. These are NATURAL tocopherols, they are NOT the synthetic, racemix dl-tocopherol or dl-tocopheryl acetate.

Tocopherol is the most commonly used form of vitamin E in cosmetic products. α-tocopherol, one of four types of tocopherol, is the most abundant form of vitamin E naturally found in the skin. α and γ forms are excreted in sebum [oil] and act as a barrier for the skin. The amount of tocopherol in the skin decreases over time due to sun exposure. Tocopherols are strong anti-oxidants. Anti-oxidants help protect against skin aging. Tocopherols use their anti-oxidant ability to protect against sun damage and repair sun damage. They increase collagen production and protect existing collagen by inhibiting matrix metalloproteinase [MMP] that degrades collagen. Mixed tocopherols have anti-inflammatory properties and accelerate wound healing.

Key benefits of Vitamin E Mixed Tocopherols in skin care:

Antioxidant [1-15]
Sun damage protection [2, 4, 7, 8, 9, 14, 15]
Sun damage repair [12]
Anti-inflammatory [2, 5, 10, 14]
Wound Healing Support [5]
Matrix Metalloproteinase [MMP] inhibitors [11]
Stimulate collagen production [5]
Reduces fine lines and wrinkles [3]

$26.30

Glucan is a polymer, produced from glucose molecules in fungi, seaweed and other organisms. Many types of this polymer exist, but yeast beta-glucan has the optimal structure and size for biological activity. It has significant effects in wound healing – glucan is already used to treat burn patients, as it promotes regeneration of the skin, reduces pain and improves scar appearance. Furthermore, it is able to activate the immune system to fight against infections, making it additionally useful in open wound care. Additionally, it helps the skin to maintain its barrier function after damage by chemicals, such as detergents. The antioxidant properties of this polymer help protect the skin cells against UV or other sources of oxidative damage. Skin ageing symptoms, such as darkening, sunburn and collagen degradation, can also be reduced by applying this compound.

Key benefits of Yeast Beta Glucan in skin care:

Sun damage protection [1], [5], [11]
Sun damage repair [1], [5], [11]
Wound healing support [1], [4]–[8]
Anti-bacterial [9], [10]
Scar care [8]
Lightening & brightening [1]
Antioxidant [1], [5], [11]
Restore barrier function [5]

$13.70

Multi Lamellar Base Cream with SeaKelp Bioferment and Sclerotium Gum (No Oil and No Polymer)

In order for skin to be healthy we need a well maintained stratum corneum. A healthy stratum corneum offers protection against environmental stress and water loss. BulkActives’ multi lamellar cream imitates the skin’s own lipid structure and enhance the skin's natural barrier function.

BulkActives’ multi lamellar cream is formulated with a new generation, European, sugar based, liquid crystals emulsifying system based on sorbitan stearate with sucrose cocoate. It is formulated specifically for DIY Skin care customers. BulkActives’ multi lamellar cream can be used as is. However, it can easily accept both water, oil, and water soluble and oil soluble powders and liquids. BulkActives’ multi lamellar cream is a great carrier for active skin care ingredients. The multi lamellar structure is ideal for even and effective delivery of skin actives into the skin.

BulkActives’ multi lamellar cream is exclusively and professionally formulated, manufactured and packaged for us by the same biochemist who manufactures our seakelp bioferment, pumpkin bioferment, and lemon bioferment.

NOTE: Based on customer feedback we have reformulated our multi lamellar cream, making it "greener' and even more elegant! In this NEW formulation we have also replaced the xantham gum with Sclerotium Gum, the preservative system combines the extremely safe, yet effective, Sodium Levulinate and Sodium Anisate, with Potassium sorbate and citric acid. This means our cream now does NOT contain parabens or phenoxyethanol.

Multi Lamellar Base Cream with SeaKelp Bioferment and Sclerotium Gum (No Oil and No Polymer):

Multi-lamellar cream offers outstanding moisturization
skin barrier repair and maintenance
optimized delivery of actives

Benefits of Liquid crystal systems:

Improved dissolution of poorly water soluble actives .
Liquid crystals can protect and facilitate the transport of fragile molecules e.g. proteins
Controlled active release:
Multilayers reduce the interfacial transport of actives dissolved in oil phase
Active delivery can be tailored depending on the active
Oleosome structure may enhance delivery of oil soluble ingredients
Hydrosome structure may enhance delivery of water soluble actives
Prolonged hydration potential:
Up to 50% water bound up in swollen water layers.
This water is less prone to evaporation.
In-vivo tests moisturization lasts 3 times longer
Effective Transepidermal Water Loss (TWEL)
Structure similar to skin

To thicken these creams after adding actives dissolved in waters add a few drops of Gelmaker Ultra (polymer emulsifier)

$20.80