SHIPPING SUSPENSIONS AND DELAYS
We are STILL ABLE to ship to the USA, the UK, France, The Netherands, Hong Kong, Japan!
Due to China's Wuhan Pneumonia Virus (aka Covid-19) lockdowns and a reduction or cancellation of flights by airlines, airmail services (including air parcel and EMS) to the following destinations are suspended:
Europe: Cyprus,Ireland,Ukraine,Moldova,Malta,Belarus,Estonia,Luxembourg,Spain,Georgia,Greece,Hungary,Belgium,Czech Rep.,Denmark,Italy, Switzerland,Finland,Iceland,Portugal,Slovenia,Sweden,Russia,Norway,Poland,Latvia,Slovak Rep.,Romania,Bulgaria,Croatia,Lithuania,Austria,Serbia,Germany
The Americas: South America, Mexico, Canada
Oceania: Nauru, Solomon Is., Tahiti Is., Fiji, Papua New, Guinea, New Zealand, Australia, Guam, State of Hawaii
Africa: The whole continent, including South Africa
Asia: Qatar,Iran,Mongolia,Saudi Arabia,Lebanon,Kuwait,Pakistan,Kazakhstan,Jordan,Turkmenistan,Azerbaijan,Sri Lanka,Kyrgyzstan,
Uzbekistan,India,Bangladesh,United Arab Emirates,Tajikistan,Oman,Bahrain,Brunei,Laos,Armenia,Turkey,Israel,Myanmar,Bhutan,Cambodia
Shipping to the USA, the UK, France, The Netherands, Hong Kong, Japan is NOT affected at this stage.
However, airmail services to all countries may be subject to delays.
Orders that have been placed, but were refused by my Post Office, will be kept on hold, and can be cancelled and refunded in full when requested via email.
Please note that we all wear masks when packing your orders.
We wipe all workspaces, bottles and pouches with alcohol before packing them into the envelopes.
Please stay home and stay safe!!!!
Vitamin E in Skincare
Vitamin E is a generic term for 8 different molecules—four tocotrienols and four tocopherols. Tocotrienols and tocopherols have different structures, giving them different biological properties. Both have α, β, γ, and δ forms that have varying chemical side chains in their structures . The generic term “vitamin E” usually refers to α-tocopherol. α- tocopherol is the most abundant molecule found in natural vitamin E, with tocotrienols in lesser quantities, around 15% . High amounts of α-tocopherol are excreted in sebm [oil], which is highly concentrated in exposed areas such as the forehead and nose where there are more sebum-producing glands .
Vitamin E must be supplemented, as the body cannot make it. It is present in limited quantities in the skin and readily depleted by UV exposure [more than 50% after 30 min exposure], creating a natural deficiency [2, 9]. Additionally, ozone has been shown to deplete natural levels of vitamin E in the skin .
Vitamin E, discovered in 1922, is one of the first known antioxidants . It is the predominant skin barrier anti-oxidant, one of the first lines of defense against sun damage . It protects the skin by preventing the breakdown of lipids [waxy molecules necessary to retain moisture and skin barrier function] by scavenging harmful free radicals. Free radicals are known to induce skin aging . Tocotrienols are thought to have higher antioxidant potential than tocopherols . Additionally, increased levels of lipid breakdown were found in patients with acne . This suggests vitamin E might play a role in acne treatment.
Vitamin E has potential to enhance the effect of preventative sunscreens and help heal sun damage. Application of tocopherols and tocotrienols before UV exposure preserves the amount of vitamin E in the skin . Application of vitamin E before UV exposure reduces edemas [fluid under the skin], redness, inflammation, and sunburn . It reduces wrinkles due to sun exposure and protects against photoaging, chronic damage due to excessive sun exposure . There is 56% less α-tocopherol in the skin of people with photoaging . Topical α-tocopherol applied to the skin of mice before UV radiation showed significant anti-oxidant activity and reduced lasting damage when applied after sun exposure . Similar results were seen in humans. A cream containing 10% tocopherols and 0.3% tocotrienols reduced photosensitivity [high skin sensitivity to sunlight] with a single application . Additionally, vitamin E has been shown to have a greater effect when combined with vitamin C to protect against sun damage .
Both tocotrienols and tocopherols have shown to have anti-aging properties . Treating fibroblasts [collagen producing cells] with tocotrienol and tocopherol increased collagen levels and reduced the activity of matrix metalloproteinases [MMPs] which degrade collagen and deteriorate the skin . This shows both tocotrienols and tocopherols may help protect the skin from aging by increasing the amount of collagen.
Vitamin E plays a role in protecting skin barrier function and synthesizing cholesterol, a component of skin that helps retain moisture . It is useful for treating burns, eczema, dryness, and ulcers . In clinical studies, α-tocopherol was shown to reduce the symptoms of eczema, an inflammatory skin disorder [5, 10].
Vitamin E also aids in wound healing [5, 10]. A study in rats shows a mixture of tocopherols and tocotrienols increases collagen at the wound site and tensile strength of the wound more than α-tocopherol alone .
Vitamin E may enhance skin penetration . Topical application of vitamin E has been shown to increase vitamin E levels in the skin better than dietary supplementation . This high absorption shows potential to enhance the penetration of other molecules.
Key benefits of Vitamin E in skin care:
- Antioxidant [2-11]
- Sun damage protection [2, 6, 9, 10, 11]
- Sun damage repair [2, 10]
- Anti-inflammatory [2, 6]
- Wound Healing Support [4, 5, 10]
- Moisturizing and hydration [5, 7, 10]
- Matrix Metalloproteinase [MMP] inhibitors 
- Collagen synthesis [3, 10]
 B. Capitanio, V. Lora, M. Ludovici, J.L. Sinagra, M. Ottaviani, A. Mastrofrancesco, M. Ardigò, and E.Camera, “Modulation of sebum oxidation and interleukin-1α levels associates with clinical improvement of mild comedonal acne,” J Eur Acad Dermatol Venereol., vol. 28, issue 12, pp. 1791-1797, December 2014.
 B. Eberlein-König and J. Ring, “Relevance of vitamins C and E in cutaneous photoprotection,” Journal of Cosmetic Dermatology, vol. 4, pp. 4-9, 2005.
 S. Makpol, F.A. Jam, S.C. Khor, Z. Ismail, Y.A.M. Yusof, and W.Z.W. Ngah, “Comparative Effects of Biodynes, Tocotrienol-Rich Fraction, and Tocopherol in Enhancing Collagen Synthesis and Inhibiting Collagen Degradation in Stress-Induced Premature Senescence Model of Human Diploid Fibroblasts,” Oxidative Medicine and Cellular Longevity, pp. 1-8, 2013.
 M. Musalmah, M.Y. Nizrana, A.H. Fairuz, A.H. NoorAini, A.L. Azian, M.T. Gapor, and W.Z. Wan Ngah, “Comparative Effects of Palm Vitamin E and a-Tocopherol on Healing and Wound Tissue Antioxidant Enzyme Levels in Diabetic Rats,” Lipids, Vol. 40, no. 6, pp. 575-580, 2005.
 G. Panin, R. Strumia, and F. Ursini, “Topical α-Tocopherol Acetate in the Bulk Phase: Eight Years of Experience in Skin Treatment,” Ann. N.Y. Acad. Sci. vol. 1031, pp. 443–447, 2004.
 V.F. Pedrelli, M.M. Lauriola, and P.D. Pigatto, “Clinical evaluation of photoprotective effect by a topical antioxidants combination [tocopherols and tocotrienols],” Journal of the European Academy of Dermatology and Venereology, vol. 26, pp. 1449-1453, 2012.
 M. Podda, C. Weber,' Maret G. Traber, and Lester Packer, “Simultaneous determination of tissue tocopherols, tocotrienols, ubiquinols, and ubiquinones,” Journal of Lipid Research, vol. 37, pp. 893-901, 1996.
 S.S. Shapiro and C. Saliou, “Role of vitamins in skin care,” Nutrition, vol. 17, issue 10, pp. 839–844,October 2001.
 A. Tavakkol, Z. Nabi, N. Soliman, and T.G. Polefka, “Delivery of vitamin E to the skin by a novel liquid skin cleanser: Comparison of topical versus oral supplementation,” J. Cosmet. Sci., vol. 55, pp.177-187, March 2004.
 J.J. Thiele, S.N. Hsieh, and S. Ekanayake-Mudiyanselage, “Vitamin E: Critical Review of Its Current Use in Cosmetic and Clinical Dermatology,” Dermatol Surg,vol. 31, pp. 805-813, 2005.
 C. Weber, M. Podda, M. Rallis, J. J. Thiele, M.G. Traber, and L. Packer, “Efficacy of Topically Applied Tocopherols and Tocotrienols in Protection of Murine Skin from Oxidative Damage Induced by UV-Irradiation” Free Radical Biology & Medicine, Vol. 22, No. 5, pp. 761–769, 1997.