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Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 Liposome Emulsion
Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 Liposome Emulsion
I am 69 and I have used this product for two years almost every day at a high dose, adding it to my antioxidant day cream, with excellent results. For me it has a very high quality and effectiveness: reduction of wrinkles, hydrated skin, unified color without blemishes ... A product of 10, the same score that I give to John for the quality of the products he sells, his excellent description / use and the bibliographic contribution.En .. ...»
María Jesus
Multi Lamellar Base Cream with SeaKelp Bioferment and Sclerotium Gum (No Oil and No Polymer)
Multi Lamellar Base Cream with SeaKelp Bioferment and Sclerotium Gum (No Oil and No Polymer)
Tried this on my week-old rash from flea bites. Got an almost instant relief and rash healed in 2 days. Tried it on my daughter who has eczema for a very long time. The rashes calmed down after a few days and her skin is now healing well. Really great product. Just put in order for another jar.... ...»
Eliz
White Willow bark (Salicin 85%)
White Willow bark (Salicin 85%)
This is great stuff. I add it to my liquid face soap and it does an excellent job in preventing acne and gently exfoliating the skin... ...»
Marie
Centella asiatica (Gotu Kola)
Centella asiatica (Gotu Kola)
Really loving this product. I make the best Centella toner and most concentrated ever. 2 g of centella extract dissolved in 10g of alcohol(you have to stir a lot) plus 88 grams of water and you get a very concentrated toner. Creams, toners, ampoules... all have only 0,1% of triterpenes, this toner i make have 1,4%. I am loving it, will see the results. .. ...»
Francisco
Pumpkin Enzyme Peel (Pumpkin Bioferment)
Pumpkin Enzyme Peel (Pumpkin Bioferment)
It is true, this product does leave the skin silky smooth! I can highly recommend using it in your masks... ...»
Mati Fuller
Green Tea (90% EGCG)
Green Tea (90% EGCG)
Just recently ordered this and LOVE! Green Tea EGCG truly is one of the most fantastic skincare actives out there. Very difficult to find good quality product (90%) and even harder to actually solubilize it! Love that it comes in pre-dissolved solution. I enjoy adding it at 1% (so 11% sol) to my serum formulations containing Niacinamide 5% + NAG 3%. Excellent for oily acne prone skin. *Only gripe... because the Pre-Dissolved Solution is SO heavy in propanediol (10 parts Propanediol for 1 part E.. ...»
Victor
Multi Lamellar Base Cream with SeaKelp Bioferment and Sclerotium Gum (No Oil and No Polymer)
Multi Lamellar Base Cream with SeaKelp Bioferment and Sclerotium Gum (No Oil and No Polymer)
Wonderful base cream! Only multi-lamellar structured cream I've found on the market. Cream itself is lightweight (no oil) yet very conditioning/hydrating. Easily accepts water-soluble active ingredients as well as oil-soluble ones. I've even pushed the additional ingred % up to 20 (meaning 80% this cream, 20% added) without any separation issues. Ideal base cream for delivering actives. Personal favorite recipe calls for 5% straight Grapeseed Oil with 5% SebumREG oil active + Panthenol 1% + E Ac.. ...»
Vic
Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 Liposome Emulsion
Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 Liposome Emulsion
excellence product, very good and made my skin soft and smooth just like baby's skin. Thank you john.. ...»
nky
Sea Kelp BioFerment (Seakelp ferment)
Sea Kelp BioFerment (Seakelp ferment)
Im 45 years old; average looking skin for my age. Applied a small pea sized amount of Sea Kelp Bioferment to my face full strength in the am after washing my face of previous night makeup.; let face "dry". Then aplied my foundation as always. Noticed my thick, heavy foundation applied more easily and smooth. Keep in mind this is DAY TWO of me using this. TWO women at work ( separate departments) commented how wonderful my face looked! One specifically came up to me and asked what I was.. ...»
Jessie Sandford
Ferulic acid (Natural)
Ferulic acid (Natural)
The Pre-dissolved solution is excellent. Ferulic Acid is an amazing skincare ingredient (potent antioxidant, protects other sensitive antioxidants from light degradation, UV protection) but is absolutely ineffective if it isn't solubilized correctly. Makes adding to any Serum Base or w/o emulsion easy. Love using it (at 6%; so active 0.5%) with the Resveratrol Fluid (10%; active 1%) and Green Tea Extr for potent nighttime brightening treatment... ...»
James
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Home » ACTIVES » Tinosorb M (Bisoctrizole)

Tinosorb M (Bisoctrizole)

Tinosorb M is the first UV filter to combine the two worlds of organic filters and micro fine inorganic pigments: it is a 50% aqueous dispersion of colorless microfine organic particles, which are less than 200nm in size and is dispersible in the water phase of an emulsion. Tinosorb M exhibits the widest UV absorption and delivers triple action: UV absorption due to the intrinsic photostable organic molecule, light scattering and reflection as a result of its microfine structure. Combining Tinosorb M and Tinosorb S Aqua has a synergic effect on both UVA and UBV protection, thus an overall enhancement on SPF

Key benefits of Tinsosorb M in skin care:

  • Can be incorporated in sunscreens, but also in day care products as well as
  • Large coverage of the UV-13 and UV-A range
  • Photostable
  • Ease of formulation
  • Less UV absorber required
  • Excellent compatibility with cosmetic ingredients and other UV filters
  • Ability to photostabilize other UV filters
  • Synergistic effect with UV-13 filters (SPF booster)
Product Code: BulkActives
Reward Points: 12
CAS#: 103597-45-1
Net weight: 50g / 1.76oz
Availability: In Stock
Price: $23.10
Reward Points: 1155


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About Tinosorb M Bisoctrizole in DIY Skin Care

Tinosorb M is an innovative UV filter with a hybrid technology that combines organic filters with inorganic micro-fine pigments. It a water soluble ingredient that is added to sunscreens to provide additional UV absorption. Tinosorb M is presented as a 50% aqueous dispersion of less than 200nm micro-particles which can be easily incorporated in a sunscreen in the water phase of an emulsion. It has numerous advantages: easy to use, can be cold processed, efficient at low concentrations and contains no preservatives.

Recent research showed that a microfine organic-inorganic technology ensures enhanced SPF and UVR coverage, because the two components have a synergic effects [1]. Tinosorb M is acts both as an organic UV filter by absorbing the UV radiation and as an inorganic filter (due to the microfine pigment particles) deflecting the ultraviolet radiation [2].


 
 Tinosorb M Bisoctrizole
 
 
 
 
 
 
 
 
 
Figure 1 – Tinosorb M organic-inorganic features [2]
 
Tinosorb M is very stable [3] and highly efficient in protecting against both UVA and UVB radiation   due to its triple action: UV absorption by a photostable organic molecule, light scattering and light reflection by its microfine structure. This enables Tinosorb M can absorb both UVA and UVB rays, providing a complete protection against the whole ultraviolet spectrum.

The active ingredient in Tinosorb M, Bisoctrizole is a broad-spectrum sunscreen that absorbs UVR and due to its microfine structure, with particles smaller than 200nm also reflects and scatters. Thus, Tinosorb M is able to succeed where other organic UV filters do not, especially in the UVB area. Research shows that formulations with Tinosorb M have efficiency comparable with zinc oxide (ZnO) and titanium dioxide (TiO2) [4].

 
Tinosorb M Bisoctrizole Broad Spectrum










Figure 2 – UVA and UVB absorption spectrum of Tinosorb M (2)

Studies assessing bisoctrizole’s safety showed that when formulated into a sunscreen, bisoctrizole has minimal skin penetration, which makes it completely suitable for cutaneous use [5]. Also, unlike other chemical (organic) sunscreens, Tinosorb M is very stable when it comes to UVR photodegradation. Furthermore, bisoctrizole acts as a stabilizing agent for less stable compounds such as avobenzone [3]. Regarding the concern that like other organic UV filters, BASF’s Tinosorb product range may disturb the estrogenic balance, by interacting with the estrogen receptors, laboratory research showed that tinosorb products are safe. No estrogenic activity was registered [6]. Concluding, it can be said that Tinosorb is not only one of the most efficient sunscreen ingredient but also that it is very safe for use.

Due to its stability and UVR coverage Tinosorb M is a great sunscreen by itself but it is also a great ingredient for more complex formulations.  Due to its stabilizing and synergic effects it can be used in combination with both organic and inorganic UV filters. Formulating Tinosorb M with Tinosorb S aqua – another member of the BASF Tinosorb product range makes one of the most efficient UV formulation available. Combining Tinosorb M with Tinosorb S aqua offers the possibility of formulating oil in water (O/W) suspension. O/W sunscreen suspensions are superior when it comes to coverage, uniform protection and efficiency [7].

O/W sunscreen formulation has several advantages: the UV filters are present in both the water and the oil phase (most sunscreens have the UV filter only in the oil phase), high efficiency at low concentration, superior SPF. And last, but not least, O/W formulations are more cosmetically appealing [8], with better skin coverage and longer skin resistance (less frequent re-applications are necessary.  


Tinsorb M Tinsorb S Aqua Emulsion














Figure 3 – oil in water emulsion with active UV filter in both water and oil phases (combination of Tinosorb M with Tinosorb S aqua) [9].
 
Combining Tinosorb M and Tinosorb S has a synergic effect on both UVA and UBV protection, thus an overall enhancement on SPF. Synergy is the phenomenon that happens when the combination of two or more UV filters has as a result a SPF higher than the sum of the individual SPFs [10].

Tinosorb S and Tinosorb M SPF













In conclusion, Tinosorb M is easy to use, safe, stable, stabilizing and one of the most efficient currently available organic UV filters [10].
 
Note that some studies (by the same authors) indicate that Tinosorb M, containing decyl glucoside, is a frequent cause of allergic contact dermatitis.

We suggest that you start out with using a small percentage of this UV filter, test it first on the inside of your elbow for a period of time and, if there are no problems, gradually increase the amount (up to 10%).
Assay: 50% Bisoctrizole
CAS#: 103597-45-1
INCI: Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (and) Aqua (and) Decyl Glucoside (and) Propylene Glycol (and) Xanthan Gum
Appearance: Aqueous white dispersion
Odor: Trace characteristic odor
pH: 10.5 - 12
Solubility: DISPERSABLE in water phase
Suggested percentage: 1 to 10% (TINOSORB M is approved as UV filter on part I of Annex VII of the European Cosmetics Directive 76/768/EEC in concentration up to 10%)

 UV Properties
Max:  305 and 360 nm (in water)
E (1 %, 1 cm): 480 (in water, 360nm)
Critical wavelength: 388 nm
UV-A / UV-B ratio: 1,0

Storage: Cool, dry place. Do not freeze. Keep away from light and moisture!
Manufacturer: BASF

 
  1. El-Boury, S., Couteau, C., Boulande, L., Paparis, E. and Coiffard, L. (2007). Effect of the combination of organic and inorganic filters on the Sun Protection Factor (SPF) determined by in vitro method. [online] Doi.org. Available at: http://doi.org/10.1016/j.ijpharm.2007.05.047 [Accessed 28 Apr. 2017].
  2. Carecreations.basf.com. (2017). TINOSORB® M | BASF's Care Creations. [online] Available at: https://www.carecreations.basf.com/product-formulations/product-highlights/product-highlights-detail/TINOSORB%20M/30482916 [Accessed 19 Apr. 2017].
  3. Chatelain, E. and Gabard, B. (2007). Photostabilization of Butyl methoxydibenzoylmethane (Avobenzone) and Ethylhexyl methoxycinnamate by Bis-ethylhexyloxyphenol methoxyphenyl triazine (Tinosorb S), a New UV Broadband Filter. Photochemistry and Photobiology, 74(3), pp.401-406.
  4. Herzog, B., Mongiat, S., Deshayes, C., Neuhaus, M., Sommer, K. and Mantler, A. (2002). In vivo and in vitro assessment of UVA protection by sunscreen formulations containing either butyl methoxy dibenzoyl methane, methylene bis-benzotriazolyl tetramethylbutylphenol, or microfine ZnO. International Journal of Cosmetic Science, 24(3), pp.170-185.
  5. Mavon, A., Miquel, C., Lejeune, O., Payre, B. and Moretto, P. (2006). In vitro Percutaneous Absorption and in vivo Stratum Corneum Distribution of an Organic and a Mineral Sunscreen. Skin Pharmacology and Physiology, 20(1), pp.10-20.
  6. Ashby, J., Tinwell, H., Plautz, J., Twomey, K. and Lefevre, P. (2001). Lack of Binding to Isolated Estrogen or Androgen Receptors, and Inactivity in the Immature Rat Uterotrophic Assay, of the Ultraviolet Sunscreen Filters Tinosorb M-Active and Tinosorb S. Regulatory Toxicology and Pharmacology, 34(3), pp.287-291.
  7. Carecreations.basf.com. (2017). TINOSORB® S | BASF's Care Creations. [online] Available at: https://www.carecreations.basf.com/product-formulations/product-highlights/product-highlights-detail/TINOSORB%20S/30481068 [Accessed 19 Apr. 2017].
  8. Google Books. (2017). Patent WO2015116899A1 - Oil-in -water emulsion sunscreen composition. [online] Available at: http://www.google.com/patents/WO2015116899A1?cl=en [Accessed 28 Apr. 2017].
  9. Carecreations.basf.com. (2017). TINOSORB® S AQUA | BASF's Care Creations. [online] Available at: https://www.carecreations.basf.com/product-formulations/product-highlights/product-highlights-detail/TINOSORB%20S%20AQUA/30480431 [Accessed 19 Apr. 2017].
  10. CIBA Chemicals - Tinosorb S Broad Spectrum UV absorber datasheet
  11. Couteau C, Pommier M, Paparis E, Coiffard LJ (June 2007). "Study of the efficacy of 18 sun filters authorized in European Union tested in vitro". Pharmazie. 62 (6): 449–52 [Accessed 19 Apr. 2017].

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