Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
Reviews
I wished i could order this in a smaller amount of 50 gr. Can i get informed when it is available ? -------------------- A. It will not be sold in smaller amounts. The review rating is meant to be for the product, not the size in which it is sold :-(.. ...»
Diana
Excellent quality, very fine texture and disperses easily when used correctly. Arrived in just seven days to London, England and with a reasonable postage fee. Very pleased... ...»
D N Bay
The best, most potent and most stable form of Vitamin C. Makes quite a difference to the appearance of mature, photo-damaged skin - don't expect results over night but with consistent use your skin will look more even and radiant!.. ...»
Judy
This ingredient has done more for my skin than anything else I've ever used. I put it into a spray facial toner and use it morning and night. I noticed the effects immediately, they were that dramatic. I will use this forever, no question... ...»
Marie
I bought this product before and I am here to buy it again! A high quality product for really good price... .. Thanks!.. ...»
Raisa
Love the fine powder ascorbic acid. I use it in a recipe for skin care along with hyaluronic acid. I'm 65 years old and absolutely no one believes it 'cause I've been doing this for years... ...»
Kathy
As all products from bulkactives, this is a really great and high-quality DYI ingredient. Along with John's friendly, reliable and very efficient service, it makes a purchase from bulkactives a very pleasant experience... ...»
Sandra
Purchased this some time ago from BulkActives and here to buy some more! Great stuff!!!!.. ...»
Kathy
I've been using Bulkactives green tea EGCG for four years. No complaints, it blends nicely my DIY anti-aging cream. I can feel a bit of toning and definitely notice the anti-inflammatory effects on my skin. Two observations that keep the rating 4 stars instead of 5: (1) A package of green tea contains significantly less weight/volume than the package of grape seed extract that I order from bulkactives. The two are combined in equal amounts in the anti-aging cream, so I find myself running o.. ...»
Theresa Andrews
I mixed it with some other water actives like Glucosamine, Niacinamide, Glutathione etc into the Pre Liposome Microemulsion and the serum was very smooth and moisturizing. As it claims, it penetrates into the skin very well. I will mix it with oil soluble actives in my next batch. .. ...»
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We sell  COSMETIC RAW MATERIALS, which are meant to be used at an appropriate percentage in a cosmetic formulation of your devising. Please do not order our products unless you know how to formulate creams and lotions with it!  

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Centella asiatica (Gotu Kola)

Centella asiatica is a tropical plant that has been used extensively in Indian medicine. It has diverse applications for skin cosmetics: firstly, it is effective in wound care, as it promotes healing of simple, infected, non-healing, or burn wounds, as well as wounds in patients with diabetes, undergoing radiotherapy or steroid medication. Centella is also used for treating scars and preventing or reducing stretch marks. The extract of this plant promotes synthesis of collagen, hydroxyproline, hyaluronic acid and cell growth factors, thus helping to maintain the elasticity, strength and general appearance of healthy skin. It also protects the skin from ageing damage, such as glycation, and UV damage, likely by activating antioxidant synthesis.

NOTE: To assist you with solubility issues, we now also sell Centella asiatica as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 15% solution gives 1% triterpenes content in final product.
  • 43% solution gives 3% triterpenes content in final product.
  • 72% solution gives 5% triterpenes content in final product.
     

Key benefits of Centella asiatica in skin care:

  • Wound healing support [1] [2] [4] [5] [8]
  • Stimulate HA production [2]
  • Stimulate collagen production [2] [4] [5] [7]
  • reduce fine lines and wrinkles [2] [4] [5] [7]
  • Increase skin elasticity [2]
  • Glycation inhibitor and repair [9]
  • Scar care [2] [4] [12]
  • Sun damage protection [9]
×
Product Code: BulkActives
Reward Points: 12
Assay: Total triterpenes 70%
CAS#: 84696-21-9
Net weight: 15g / 0.53oz & 100g / 3.53oz
Availability:
Standardized preDissolved solution 100g - Options Out of Stock
Standardized Powder 15g - Options In Stock
Price: $23.40
Reward Points: 1210


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About Centella Asiatica in DIY Skin Care

centella asiatica in skin careCentella asiatica is a tropical herb, growing in the tropical regions of America, Africa and Asia, where it is also called Gotu kola. Its extracts are used in various pharmaceutical and cosmeceutical preparations, designed for a wide range of purposes. Centella is well-known in Indian medicine, where the extracts are used to treat eczema, psoriasis and even syphilis, while others report its antidepressant and analgesic power [1]. The pharmacological effect of these extracts is ascribed to three chemicals – asiatic acid, madecassic acid and asiaticoside [2].

Foremost usage of Centella is in wound care. It may be used to treat non-healing and infected wounds, scars, burns and even alleviate radiotherapy damage [2], [3]. In rats, applying Centella cream three times a day for 24 days even on open wounds increased cellular proliferation and collagen synthesis at the wound site, making them heal faster [4]. An increase in collagen content and tensile strength were also observed. In guinea pigs, asiaticoside was also found to improve the amounts of collagen, together with faster healing [5]. Asiaticoside was effective even against delayed-healing wounds in both human and animal studies with no observed side effects, marking the importance of Centella for diabetes patients [5], [6]. Centella asiatica can also overcome the anti-healing effect of steroid drugs [1].

The three main active ingredients of Centella were shown to increase both collagen and hydroxyproline content (one of the building blocks of collagen) in cells and extracellular areas, suggesting remodeling of the tissue at wound sites. It is believed that these compounds promote cell proliferation, as well as growth factor production and activation [2], [7]. Asiaticoside was also found to induce synthesis of natural antioxidants, among them vitamin E, C and catalase, in rats. This effect is believed to help at early stages of wound healing [8]. Besides the effect on collagen, each of the tested ingredients was also able to stimulate the synthesis of hyaluronic acid [2]. Recent research suggests even new applications for Centella extracts. It has been successfully used on human skin to reduce ageing damage, caused by inflammation and glycation [9]. It also protects against UV and reduces darkening after UV exposure [9], [10]

Centella can be combined with other ingredients to achieve synergistic effects. A herbal ointment containing Centella and other plant extracts was found to improve the appearance of dermatitis patients’ skin under dry or cold weather conditions [11]. Combined with onion extract, Centella cream has successfully improved the stretch mark appearance, as evaluated both by participating women and the researchers [12]. Similar effect (reduced severity of stretch marks and even prevention) was found using a cream where Centella is combined with other ingredients, such as vitamin E, suggesting that the extract of this plant is responsible for the primary effect in scar treatment [13]. Addition of vitamins A, E or C also strengthens the collagen-promoting effect of Centella [7]. In patients with photoaged (UV-damaged) skin, dermally applied madecassoside (extracted from Centella) and vitamin C preparation resulted in a significant improvement in firmness, elasticity and skin hydration, confirmed by objective measurements [14]. Finally, recommended usage of Centella extracts is 1 % in cream or 2 % in powder form [2].
 

NOTE: To assist you with solubility issues, we now also sell Centella asiatica as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

Centella Asiatica Standardized Powder

Assay: Total triterpenes 70%(Asiaticoside & Macassoside 70%)
CAS#:16830-15-2
INCI: Centella asiatica (Gotu Kola) extract
Source: Centella asiatica
Appearance: powder
Solubility: 1,3-Propanediol
Suggested percentage: 1 to 10%

Storage: Store in cool and dry place. Keep away from direct strong light and heat
Country of origin: China

Centella Asiatica Standardized Pre Dissolved Solution - 10%

Assay: 9.9% Centella asiatica
CAS#: 504-63-2,16830-15-2
INCI: 1,3-Propanediol, Centella asiatica
Appearance: liquid

Solubility: add to cream
Suggested percentages:
15% solution gives 1% triterpenes content in final product.
43% solution gives 3% triterpenes content in final product.
72% solution gives 5% triterpenes content in final product.

Storage: Store in fridge, do not freeze.
Country of origin for raw material: China
Country of manufacture: Taiwan
[1]          B. S. Shetty, S. L. Udupa, A. L. Udupa, and S. N. Somayaji, “Effect of Centella asiatica L (Umbelliferae) on normal and dexamethasone-suppressed wound healing in Wistar Albino rats,” Int. J. Low. Extrem. Wounds, vol. 5, no. 3, pp. 137–143, Sep. 2006.
[2]          W. Bylka, P. Znajdek-Awiżeń, E. Studzińska-Sroka, A. Dańczak-Pazdrowska, and M. Brzezińska, “Centella asiatica in dermatology: an overview,” Phytother. Res. PTR, vol. 28, no. 8, pp. 1117–1124, Aug. 2014.
[3]          W. Bylka, P. Znajdek-Awiżeń, E. Studzińska-Sroka, and M. Brzezińska, “Centella asiatica in cosmetology,” Adv. Dermatol. Allergol. Dermatol. Alergol., vol. 30, no. 1, pp. 46–49, Feb. 2013.
[4]          Sunilkumar, S. Parameshwaraiah, and H. G. Shivakumar, “Evaluation of topical formulations of aqueous extract of Centella asiatica on open wounds in rats,” Indian J. Exp. Biol., vol. 36, no. 6, pp. 569–572, Jun. 1998.
[5]          A. Shukla, A. M. Rasik, G. K. Jain, R. Shankar, D. K. Kulshrestha, and B. N. Dhawan, “In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica,” J. Ethnopharmacol., vol. 65, no. 1, pp. 1–11, Apr. 1999.
[6]          V. Paocharoen, “The efficacy and side effects of oral Centella asiatica extract for wound healing promotion in diabetic wound patients,” J. Med. Assoc. Thail. Chotmaihet Thangphaet, vol. 93 Suppl 7, pp. S166–170, Dec. 2010.
[7]          P. Hashim, “The effect of Centella asiatica, vitamins, glycolic acid and their mixtures preparations in stimulating collagen and fibronectin synthesis in cultured human skin fibroblast,” Pak. J. Pharm. Sci., vol. 27, no. 2, pp. 233–237, Mar. 2014.
[8]          A. Shukla, A. M. Rasik, and B. N. Dhawan, “Asiaticoside-induced elevation of antioxidant levels in healing wounds,” Phytother. Res., vol. 13, no. 1, pp. 50–54, 1999.
[9]          G. Maramaldi, S. Togni, F. Franceschi, and E. Lati, “Anti-inflammaging and antiglycation activity of a novel botanical ingredient from African biodiversity (CentevitaTM),” Clin. Cosmet. Investig. Dermatol., vol. 7, pp. 1–9, 2013.
[10]        E. Jung, J.-A. Lee, S. Shin, K.-B. Roh, J.-H. Kim, and D. Park, “Madecassoside inhibits melanin synthesis by blocking ultraviolet-induced inflammation,” Mol. Basel Switz., vol. 18, no. 12, pp. 15724–15736, 2013.
[11]        W. Klövekorn, A. Tepe, and U. Danesch, “A randomized, double-blind, vehicle-controlled, half-side comparison with a herbal ointment containing Mahonia aquifolium, Viola tricolor and Centella asiatica for the treatment of mild-to-moderate atopic dermatitis,” Int. J. Clin. Pharmacol. Ther., vol. 45, no. 11, pp. 583–591, Nov. 2007.
[12]        Z. D. Draelos, M. H. Gold, M. Kaur, B. Olayinka, S. L. Grundy, E. J. Pappert, and B. Hardas, “Evaluation of an onion extract, Centella asiatica, and hyaluronic acid cream in the appearance of striae rubra,” Skinmed, vol. 8, no. 2, pp. 80–86, Apr. 2010.
[13]        J. Á. García Hernández, D. Madera González, M. Padilla Castillo, and T. Figueras Falcón, “Use of a specific anti-stretch mark cream for preventing or reducing the severity of striae gravidarum. Randomized, double-blind, controlled trial,” Int. J. Cosmet. Sci., vol. 35, no. 3, pp. 233–237, Jun. 2013.
[14]        M. Haftek, S. Mac-Mary, M.-A. L. Bitoux, P. Creidi, S. Seité, A. Rougier, and P. Humbert, “Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin,” Exp. Dermatol., vol. 17, no. 11, pp. 946–952, 2008.

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