Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
Reviews
Carla, Many medications can be and are applied topically by prescription. With that in mind, realize that this particular ingredient is wonderful but understand that this is indeed one of those that may create sensitivity with those already using topical hormones or just use sparingly and see how you respond. Sorry for the very late response..... ...»
Angela
Im 45 years old; average looking skin for my age. Applied a small pea sized amount of Sea Kelp Bioferment to my face full strength in the am after washing my face of previous night makeup.; let face "dry". Then aplied my foundation as always. Noticed my thick, heavy foundation applied more easily and smooth. Keep in mind this is DAY TWO of me using this. TWO women at work ( separate departments) commented how wonderful my face looked! One specifically came up to me and asked what I was.. ...»
Jessie Sandford
Very good product! Only been using it for a short time, its already made a difference. .. ...»
Bronwynne
muy satisfecho profesionales, y envio sin problemas ,ya que soy de españa producto bien envasado , un placer ser cliente porque dan comnfianza y calidad.gracias un saludo.. ...»
daniel
Wanting to try this, but.... Angela, what was that about effecting hormones? Could someone explain please..... ...»
Carla
I am following the moisturizing cream + Zinc dispersion recipe and I am extremely satisfied. I do allow for a little time for it to absorb in & then I dab off anything that I feel looks a little white - but that's because I initially use a fairly thick coating on myself. I use a bit of foundation at times on top and there are no issues as far as weird colors or texture issues. I am so grateful for this entire website as a one-stop-shop for such effective skin care products, and now we can.. ...»
Peggy
Excellent quality, very fine texture and disperses easily when used correctly. Arrived in just seven days to London, England and with a reasonable postage fee. Very pleased... ...»
D N Bay
I just placed my first order for SEaKelp Bioferment from Bulk Actives and was pleased to receive it very quickly.. ...»
Viki
I purposely waited a few months before writing my review. I am happy to report this product is great! I combined the DMAE product with the base creams resulting in tighter skin and lessened wrinkles, including areas around underarms... ...»
cjmluv
Very good product. It performed exactly how I expected. .. ...»
Ryan
Secure Payments
Orders Securely Processed Through PayPal
PayPal
 Visa  Mastercard  Discover  American Express
 

SSL Certificate

As Featured On EzineArticles

Google+

 

 

 

Important Stuff

 All customers PLEASE read:

 the FAQ and Delivery Info pages!

Canadian Customers:

Any long delivery delays are caused by The Canada Border Services Agency.
I now ONLY offer EMS as a shipping option to Canada. 
This appears to have resolved most of the delays caused by The Canada Border Services Agency.

Please write your correct address:

We take NO responsibility for delivery issues caused by customers entering the wrong address in the checkout page

Delivery

BulkActives is a part-time business. Orders are processed and mailed on Saturdays. (TimeZone Order Deadline Chart)

What we sell

We sell  COSMETIC RAW MATERIALS, which are meant to be used at an appropriate percentage in a cosmetic formulation of your devising. Please do not order our products unless you know how to formulate creams and lotions with it!  

Forgotten your password? Not receiving lost password emails? Can't create an account?

NO PROBLEM!  Just email me, and I will sort it all out.

Not receiving order status email updates?

Please check your JUNK mail folder for our emails, and mark them as NOT SPAM.

Failing to do so will result in NOT receiving ANY transaction / order status email updates.

Recipe % calculator

Download our SIMPLE RECIPE CALCULATOR (MS Excel)

Sample Recipes

Download sample recipes RAR file

Newsletter
* E-mail Address:
* Name:
Recent Articles

Antioxidants for sun damage protection (photoprotection)

How the skin naturally protects itself and the advantages of topical antioxidants for photoprotection The...

Read article


Ascorbyl Glucoside in Skin Care (AA2G, stable Vitamin C)

Ascorbyl Glucoside or AA2G is a derivative of vitamin C that has been biochemically modified to make...

Read article


Anhydrous C for skin care: L-ascorbic in silicone

Anhydrous C for skin care: absorption of L-ascorbic in a silicone base Anhydrous C is a skin care product...

Read article


Enhancing skin tone and reversing the effects of ageing

Enhancing skin tone and reversing the effects of ageing It is only in recent times that researchers...

Read article


How to boost collagen production in skin

What is Collagen? Collagen is a major structural protein in the skin. It plays a key role in providing...

Read article


Alcohol as Solvent in DIY Skin Care Products

Alcohol is a generic name for organic chemical compounds usually obtained through fermentation. Despite...

Read article


Hyperpigmentation,Melasma, and Skin Color Explained

The enzyme tyrosinase converts the amino acid tyrosine into melanin in the skin. Hyperpigmentation can...

Read article


Improve skin tone and reverse the effects of aging

Latest developments in agents that improve skin tone and reverse the effects of aging Beauty, they say,...

Read article


Made in China - Getting to the Heart of the Matter

After getting a couple of emails about products manufactured in China, I wanted to take the time to write...

Read article


Exfoliating: Mild Chemical Exfoliating in Skin Care

Exfoliating is a cosmetic procedure that involves the removal of dead skin cells that accumulate in the...

Read article


Multi Lamellar Creams and Emulsions

Multi Lamellar Emulsions (MLE) The protective properties of our skin are determined by its complex biological...

Read article


Oat Beta Glucan Skin Care

Oat Beta Glucan Skin Care - Anti Wrinkle Skin Care and Skin Texture Improvements Oat beta glucan has...

Read article


UV Skin Damage - Photodamage and Photoaging

UV skin damage: Photodamage, photoaging and other ways in which the skin changes due to exposure to UV...

Read article


Skin Lightening Process and Pigmentation Formation

Pigmentation formation and skin lightening process Melanin is mainly responsible for skin pigmentation,...

Read article


Resveratrol – nature’s most powerful and potent anti-aging agent yet

The process of aging is one that man has battled with for a long time. A lot of research has been done...

Read article


Rosehip Oil and Vitamin A in Skin Care

Rosehip oil is widely recognized for the effects of the natural topical trans-retinoic acid (vitamin...

Read article


Silymarin Skin Health – Antioxidant & Anti-inflammatory

Silymarin Skin Health – Antioxidant, Anti-inflammatory, Skin Cancer Preventative In the world of skin...

Read article


Exfoliating Skin with Salicylic Acid

Salicylic acid - a beta hydroxy acid as anti-inflammatory, exfoliating, and anti acne active What is...

Read article


soy isoflavones skin benefits

Soy isoflavones skin benefits in anti aging skin care Research suggests that estrogen deficiencies...

Read article


Sunscreens With Vitamin A are Potentially Harmful for Skin

Sunscreens With Vitamin A are Potentially Harmful for Skin The impact of vitamin A on skin health has...

Read article


Antioxidants for sun damage protection (photoprotection)

How the skin naturally protects itself and the advantages of topical antioxidants for photoprotection The...

Read article

Ascorbyl Glucoside in Skin Care (AA2G, stable Vitamin C)

Ascorbyl Glucoside or AA2G is a derivative of vitamin C that has been biochemically modified to make...

Read article

Anhydrous C for skin care: L-ascorbic in silicone

Anhydrous C for skin care: absorption of L-ascorbic in a silicone base Anhydrous C is a skin care product...

Read article

Enhancing skin tone and reversing the effects of ageing

Enhancing skin tone and reversing the effects of ageing It is only in recent times that researchers...

Read article

How to boost collagen production in skin

What is Collagen? Collagen is a major structural protein in the skin. It plays a key role in providing...

Read article

Alcohol as Solvent in DIY Skin Care Products

Alcohol is a generic name for organic chemical compounds usually obtained through fermentation. Despite...

Read article

Hyperpigmentation,Melasma, and Skin Color Explained

The enzyme tyrosinase converts the amino acid tyrosine into melanin in the skin. Hyperpigmentation can...

Read article

Improve skin tone and reverse the effects of aging

Latest developments in agents that improve skin tone and reverse the effects of aging Beauty, they say,...

Read article

Made in China - Getting to the Heart of the Matter

After getting a couple of emails about products manufactured in China, I wanted to take the time to write...

Read article

Exfoliating: Mild Chemical Exfoliating in Skin Care

Exfoliating is a cosmetic procedure that involves the removal of dead skin cells that accumulate in the...

Read article

Multi Lamellar Creams and Emulsions

Multi Lamellar Emulsions (MLE) The protective properties of our skin are determined by its complex biological...

Read article

Oat Beta Glucan Skin Care

Oat Beta Glucan Skin Care - Anti Wrinkle Skin Care and Skin Texture Improvements Oat beta glucan has...

Read article

UV Skin Damage - Photodamage and Photoaging

UV skin damage: Photodamage, photoaging and other ways in which the skin changes due to exposure to UV...

Read article

Skin Lightening Process and Pigmentation Formation

Pigmentation formation and skin lightening process Melanin is mainly responsible for skin pigmentation,...

Read article

Resveratrol – nature’s most powerful and potent anti-aging agent yet

The process of aging is one that man has battled with for a long time. A lot of research has been done...

Read article

Rosehip Oil and Vitamin A in Skin Care

Rosehip oil is widely recognized for the effects of the natural topical trans-retinoic acid (vitamin...

Read article

Silymarin Skin Health – Antioxidant & Anti-inflammatory

Silymarin Skin Health – Antioxidant, Anti-inflammatory, Skin Cancer Preventative In the world of skin...

Read article

Exfoliating Skin with Salicylic Acid

Salicylic acid - a beta hydroxy acid as anti-inflammatory, exfoliating, and anti acne active What is...

Read article

soy isoflavones skin benefits

Soy isoflavones skin benefits in anti aging skin care Research suggests that estrogen deficiencies...

Read article

Sunscreens With Vitamin A are Potentially Harmful for Skin

Sunscreens With Vitamin A are Potentially Harmful for Skin The impact of vitamin A on skin health has...

Read article

Buy D-Panthenol USP (Liquid) For Skin Care

D panthenol (Dexpanthenol) is the stable alcohol form of pantothenic acid (vitamin B5). D panthenol is well absorbed through the skin where it is rapidly converted enzymatically to pantothenic acid, a component of coenzyme A (CoA), which is important in cellular skin metabolism. Application of D panthenol is commonly used in wound management because it stimulates skin regeneration via fibroblasts proliferation and promotes wound healing. Many clinical in vivo studies provide experimental evidence of the beneficial effects of topically applied D panthenol. Studies have proved that topical usage of D panthenol enhances skin barrier repair and reduces TEWL thus being an effective moisturizer. Last but not least, the anti-inflammatory properties of D panthenol make it effective in treating various dermatologic diseases or as an adjuvant in cosmetic therapies. D panthenol has zero toxicity and it is well tolerated both topically and orally thus appropriate for human consumption and use. 

Key benefits of D-Panthenol USP in skin care:

  • Moisturizing and hydration [3]-[6]
  • Wound healing support [7] [8]
  • Anti-inflammatory [9]-[12] [15]
  • Sun damage repair [12]
  • Anti-acne [13][14]
  • Oil/sebum control [13]
D-Panthenol USP (Liquid) skin care active ingredients
Product Code: BulkActives
Reward Points: 14
Assay: 99%
CAS#: 81-13-0
Net weight: 250g / 8.82oz
Availability: In Stock
Price: $27.00
Reward Points: 1350


    - OR -   Add to Wish List
Add to Compare
Did you find this somewhere else for less? Let us know and we'll match it! (conditions apply)
×
* Name:
* Email:
Telephone:
* Competitor link
* Competitor price
Message

D-Panthenol USP (Liquid)

About D Panthenol USP (Liquid) in DIY Skin Care

D panthenol (Dexpanthenol), also known as provitamin B5, is the stable alcohol form of pantothenic acid which is a key player in maintenance of epithelial function and skin regrowth, being a normal constituent of skin and hair.D panthenol is not found naturally, thus synthetic dexpanthenol is converted to pantothenic acid in the skin, stimulating skin regeneration in a manner comparable to vitamin A. This process of cell division and formation of new skin tissue restores skin elasticity and promotes wound healing [1].
 
Due to its anti-inflammatory properties and its solubility dexpanthenol is used in the treatment of various conditions such as: acnea vulgaris, alopecia, lupus, wound healing, with extrapolated research to other epithelial diseases such as celiac disease and other digestive tract conditions. D panthenol has very low toxicity and inexistent adverse reactions, making it suitable for human consumption and use [2]
 
D panthenol is water soluble and hydroscopic and has skin moisturization potential, especially when combined with the widely used moisturizing agent glycerol [3]. D panthenol based formulations increased skin moisture in stratum corneum and had a significant effect on skin barrier function by decreasing TEWL (Transepidermal Water Loss) values and improving the skin barrier function in addition [4] Studies emphhasised that treatment with a dexpanthenol-containing cream significantly enhances skin barrier repair and stratum corneum hydration, while reducing skin roughness and inflammation. [5] [6].
 
D panthenol is responsible for in vitro and in vivo activation of fibroblast proliferation, which is of relevance in wound healing. Accelerated re-epithelization in wound healing, monitored by means of the transepidermal water loss as an indicator of the intact epidermal barrier function, has also been seen [7]. In vivo wound–healing studies revealed considerable effects of dexpanthenol on gene regulation in comparison to placebo treatment in all samples. An upregulation of 95 genes could be detected after D panthenol treatment [8].
 
D panthenol exhibits protective effects against skin irritation with applications in contact dermatitis, a condition affecting a large pool of individuals both in domestic and professional situations. D panthenol exhibits protective effects against skin irritation, both in vitro and in vivo situations [9].  Another application of D panthenol is the treatment of atopic dermatitis (AD), a common chronic relapsing disease particularly affecting children. The emollient used for protection of skin barrier function is the standard treatment for patients with AD. The topical treatment with D panthenol ointment is as effective as hydrocortisone, with no statistical difference between them. Concluding, dexpanthenol ointment may be used as alternative treatment in mild to moderate childhood AD therapy avoiding long term side effects of hydrocortisone [10]. D panthenol is also involved in the process of reducing UV induced erythema.  The efficacy of the active was assessed by colorimetry via the reduction of redness and by measuring the change in microcirculation by laser Doppler [11] [12].
 
Dexpanthenol has been shown to reduce acnea vulgaris and its effect. Under topical treatment the face became noticeably less oily and a decrease in facial sebum secretion occurred, facial pore size had become noticeably smaller, existing acne lesions had begun to heal, and the rate of new acne eruptions had slowed, finally getting the disease under control. It was shown that the gravity of the acne needs to be approached with proportional higher dexpanthenol dosage [13]. D panthenol is also an adjuvant in healing post acne-treatment scars and inflammation. Dexpanthenol cream signifcantly improves mucocutaneous side effects associated with isotretinoin therapy [14]
 
The latest tendencies are to use the moisturizing and anti-inflammatory properties of dexpanthenol as adjuvant in cosmetic procedures. D panthenol based ointments were successfully used in reducing effects of chemical peeling and laser rejuvenation therapies [15].
 
Assay: 99%
CAS#: 81-13-0
INCI: Panthenol
Synonyms: D-Panthenol, dexpanthenol, D-pantothenyl alcohol, provitamin B5
Appearance: Pure D-Panthenol USP is a colourless, clear, highly viscous, hygroscopic liquid
Solubility: D-Panthenol is readily miscible with water, ethanol, methanol and propylene glycol.
Suggested percentage: 1 to 5%  (too much will make your skin care product sticky)
Stability: D-Panthenol is stable to air and light but not heat, If it is stored at around 20° C in the unopened, original containers, it has a shelf life of at least 12 months. In weakly acidic, aqueous solutions, D-Panthenol is considerably more stable than the salts of pantothenic acid.
Storage: Store in cool and dry place in closed container. Keep away from direct strong light and heat. can solidify on prolonged storage.
Manfacturer: BASF (Germany)
[1]    L. Baumann, “Cosmeceutical Critique Compendium”, Skin and allergy news, 2006
[2]    G.S. Kelly, “Pantothenic Acid”, Alternative Medicine Review, 16, pp 263-274, 2001
[3]    D.L. Bissett, “Common cosmeceuticals”, Clinics in Dermatology, 27, pp 435–445, 2009
[4]    F .B. Camargo, Jr., L.R. Gaspar, P.B.G. Maia Campos, “Skin moisturizing effects of panthenol-based formulations”, Journal of Cosmetic Science, no 62,  pp 361–369, 2011
[5]    E. Proksch, H.P. Nissen, “Dexpanthenol enhances skin barrier repair and reduces inflammation after sodium lauryl sulphate-induced irritation”,  Journal of dermatology treatments, 13, pp 173-178, 2002
[6]    W. Gehring, M. Gloor, “Effect of topically applied dexpanthenol on epidermal barrier function and stratum corneum hydration. Results of a human in vivo study”, Arzneimittel-Forschung,  50, pp 659-663, 2002
[7]    F. Ebner, A. Heller, F. Rippke, I. Tausch, “Topical use of dexpanthenol in skin disorders”, American Journal of Clinical Dermatology, 3, pp 427-433, 2002
[8]     R. Heise, C. Skazik, Y. Marquardt,  K. Czaja,  K. Sebastian, P. Kurschat, L. Gan,  B. Denecke, S. Ekanayake-Bohlig, K.-P. Wilhelm, H.F. Merk, J.M. Baron, “Dexpanthenol Modulates Gene Expression in Skin Wound Healing in vivo”, Skin Pharmacology and Phisiology, 25, pp 241-248, 2012
[9]    K.Biro, D. ThaÇi, F. R. Ochsendorf, R. Kaufmann, W.H. Boehncke, “Efficacy of dexpanthenol in skin protection against irritation: a double-blind, placebo-controlled study”, Contact Dermatitis, 9, pp 80-84, 2003
[10]    M. Udompataikul, D. Limpa-o-Vart, “Comparative trial of 5% dexpanthenol in water-in-oil formulation with 1% hydrocortisone ointment in the treatment of childhood atopic dermatitis: a pilot study”, Journal of Drugs in Dermatology”, 11, pp 366-374, 2012
[11]    W.Baschong, D. Huglind, J. Roding, “D-panthenol loaded nanotopes<TM> providing enhanced anti-inflammatory efficacy: A study on human volunteers”, Seifen Öle Fette Wachse, 125: pp. 29-30
[12]    H.D.Tauschel,C.Rudolph, “Untersuchungen zur perkutanen Wirksamkeit einer Heparin-Allantoin-Dexpanthenol-Kombination in spezieller Salbengrundlage: Antiinflammatorische Wirkung auf UV-Erytheme am Meerschweinchen”, Arzneimittel Forschung, 32, pp. 1096-1100, 1982
[13]    H.L. Leung,“Pantothenic acid defciency as the pathogenesis of acne vulgaris”, Med Hypotheses, 44:490-492. 1995
[14]     R. Romiti, N.Romiti, “Dexpanthenol cream signi!cantly improves mucocutaneous side effects associated with isotretinoin therapy”,  Pediatric Dermatology, 19:368, 2002   
[15]    N.V. Gaidash, E.A. Karassyov, V.V. Mordortseva, “Personal experience in the use of dexpanthol for skin care after chemical peeling and photo-rejuvenation procedures”, Journal of Applied Cosmetology, 27, pp 111-115, 2009

Write a review

Your Name:


Your Review: Note: HTML is not translated!

Rating: Bad           Good

Enter the code in the box below:



(c) BulkActives 2005-2017