Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
Reviews
This lovely, simple, and affordable product has become something I don't want to be without. I am 47, with very sensitive and reactive dry skin. This cream doesn't feel particularly moisturizing and leaves something of a 'dry' finish on the skin after application, but it's had SUCH a positive impact on my face. The redness and papules from my rosacea and seb derm have reduced by a good 90%. It's been a magical barrier restorer and I panicked when it was temporarily out of stock. I would recomme.. ...»
Candace Carnahan
This is the best product I have ever used on my skin and I tried a LOT of expansive brands. It helps with redness and overall skin tone. Please do not ever stop making this stuff... ...»
Helena
I' m not sure about this: "11% solution gives 1% EGCG content in final product." What is the weight of final product? .. ...»
Vesna Hanich
Tried this on my week-old rash from flea bites. Got an almost instant relief and rash healed in 2 days. Tried it on my daughter who has eczema for a very long time. The rashes calmed down after a few days and her skin is now healing well. Really great product. Just put in order for another jar.... ...»
Eliz
This is great stuff. I add it to my liquid face soap and it does an excellent job in preventing acne and gently exfoliating the skin... ...»
Marie
Really loving this product. I make the best Centella toner and most concentrated ever. 2 g of centella extract dissolved in 10g of alcohol(you have to stir a lot) plus 88 grams of water and you get a very concentrated toner. Creams, toners, ampoules... all have only 0,1% of triterpenes, this toner i make have 1,4%. I am loving it, will see the results. .. ...»
Francisco
Just recently ordered this and LOVE! Green Tea EGCG truly is one of the most fantastic skincare actives out there. Very difficult to find good quality product (90%) and even harder to actually solubilize it! Love that it comes in pre-dissolved solution. I enjoy adding it at 1% (so 11% sol) to my serum formulations containing Niacinamide 5% + NAG 3%. Excellent for oily acne prone skin. *Only gripe... because the Pre-Dissolved Solution is SO heavy in propanediol (10 parts Propanediol for 1 part E.. ...»
Victor
Wonderful base cream! Only multi-lamellar structured cream I've found on the market. Cream itself is lightweight (no oil) yet very conditioning/hydrating. Easily accepts water-soluble active ingredients as well as oil-soluble ones. I've even pushed the additional ingred % up to 20 (meaning 80% this cream, 20% added) without any separation issues. Ideal base cream for delivering actives. Personal favorite recipe calls for 5% straight Grapeseed Oil with 5% SebumREG oil active + Panthenol 1% + E Ac.. ...»
Vic
Im 45 years old; average looking skin for my age. Applied a small pea sized amount of Sea Kelp Bioferment to my face full strength in the am after washing my face of previous night makeup.; let face "dry". Then aplied my foundation as always. Noticed my thick, heavy foundation applied more easily and smooth. Keep in mind this is DAY TWO of me using this. TWO women at work ( separate departments) commented how wonderful my face looked! One specifically came up to me and asked what I was.. ...»
Jessie Sandford
Carla, Many medications can be and are applied topically by prescription. With that in mind, realize that this particular ingredient is wonderful but understand that this is indeed one of those that may create sensitivity with those already using topical hormones or just use sparingly and see how you respond. Sorry for the very late response..... ...»
Angela
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 the FAQ and Delivery Info pages!

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Near The End

BulkActives has been in business since 2005, we might have disappeared from google search results, but we're still hanging on, just, mainly thanks to the support of some loyal customers.

However, like many, COVID hit us hard, and we're having a lot of trouble recovering.

Right now, we have not restocked many powders, however, are looking at continuing with selling only our flagship products:

seakelp and pre-dissolved powders, and some of the essentials.

Phytosterol

Phytosterols are a family of plant-produced molecules with diverse health benefits. In cosmetics, the ability to stimulate collagen production is most interesting. Together with antioxidant activity and down-regulation of collagen degrading enzymes, these abilities help repair damage in photoaged skin. Phytosterols also have anti-inflammatory properties, which are useful in UV protection, dermatitis treatment, and even cancer prevention. They are widely used in burn wound care – phytosterols were found to improve healing, improve scar appearance and possess analgesic properties, reducing the need of opiate drugs. Antimicrobial activity of phytosterols is also important in skin care, as it can be utilized in both wound care and general fight against infections, such as Candida. Finally, phytosterols regulate transport of cholesterol and thus sebum production – this may present a good treatment option for acne and other sebum-related conditions.

NOTE: To assist you with solubility issues, we now also sell Phytosterol in a standardized  pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 11% solution gives 1% Phytosterols content in final product.
    32% solution gives 3% Phytosterols content in final product.
    53% solution gives 5% Phytosterols content in final product.

Key benefits of Phytosterols in skin care:

  • Anti-inflammatory [2], [12]–[14]
  • Anti-bacterial [6], [7]
  • Oil/sebum control [8]
  • Anti-acne [8]
  • Sun damage protection [10], [11]
  • Stimulate collagen production [9]–[11]
  • Restore barrier function [5]
  • Matrix metalloproteinase (MMP) inhibitors [9]–[11]
  • Wound healing support [3]–[5]
  • Scar care [3]–[5]
×
Product Code: BulkActives
Assay: 95%
CAS#: 68555-08-8
Net weight: 30g /1.06oz & 100g / 3.53oz
Availability:
Standardized preDissolved solution 150g - Options Out of Stock
Standardized Powder 30g - Options In Stock
Price: $6.45


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About Phytosterol in Skin Care

Phytosterols or plant sterols is a common name for several plant-produced molecules. These molecules cannot be produced in human body, and usually are obtained from oil, nuts and general vegetarian diet. The most abundant plant sterols are campesterol, stigmasterol and beta-sitosterol, with the latter being most important biologically [1]. Other sterols, however, are also continuously investigated, and new applications are being discovered every year.

Beta-sitosterol is most known for its use in wound care. Its anti-inflammatory activity was described long ago, and it is also an antipyretic (reduces fever) of similar strength to aspirine [2]. These properties led to the development of a burn ointment using beta-sitosterol as main active ingredient. It is used to accelerate healing, reduce scarring, and prevent bacterial growth [3], [4]. Clinical studies found that this treatment also helps restore the barrier function of the skin, measured by reduced water loss. Interestingly, this effect was found to be associated with better scar appearance, demonstrating a relation between clinical and cosmetical functions [5]. Improved scar appearance can be already observed after 1 month of treatment, which is relatively fast for scar-treating cosmeceuticals [4]. Furthermore, this ointment has an analgesic effect, with patients requiring much less opiate painkillers while using this mixture [3].

The antibacterial effect of plant sterols is useful in both wound care and general hygiene. While investigating an extract from Alpinia conchigera, researchers found that the main components were phytosterols – stigmasterol and beta-sitosterol [6]. This extract had a strong effect against various pathogenic microbes, including fungi, such as Candida albicans, and even generally resistant bacteria, such as Staphylococcus aureus MRSA strains. Other plant sterol extracts, such as one produced from Aloe vera, also are effective against Candida and other pathogens [7].
Phytosterols also have health benefits in other areas. They reduce the levels of LDL cholesterol, commonly known as “bad cholesterol” [1]. This is relevant not only to the cardiovascular system, as cholesterol accumulation in the skin causes seborrhea, acne, rosacea and other skin diseases. Dermal application of plant sterols can be used to reduce cholesterol transport into skin cells, and thus prevent the cholesterol-related disorders [8].

In the recent years, new collagen-restoring effects of phytosterols have been discovered. Skin cells, treated with phytosterols found in yam plant (diosgenin, stigmasterol and beta-sitosterol), had reduced levels of collagen-degrading enzymes, resulting in significantly enhanced collagen secretion [9]. Spinasterol, another phytosterol, can both increase the synthesis of collagen and decrease the synthesis of degrading enzymes [10]. Fucosterol also has these effects, and additionally promotes antioxidant enzyme synthesis. These benefits were confirmed using skin cells treated with UV (photoaged skin), proving that phytosterols are beneficial for solar protection as well [10], [11]. Dermal applications of spinasterol also reduce edema, indicating anti-inflammatory properties [12]. Furthermore, atopic dermatitis, an inflammatory disease, can be treated with applications of beta-sitosterol [13]. In fact, by reducing inflammation, beta-sitosterol and other phytosterols even reduce the likelihood of cancer development [14].
 
NOTE: To assist you with solubility issues, we now also sell Phytosterol in a standardized  pre-dissolved solution. Just add the liquid to your cream and mix well.

Phytosterol Standardized Powder

Assay: 95%
CAS No. 68555-08-8
INCI: Phytosterols
Appearance: powder
Solubility: Ethyl Hexyl Palmitate
Suggested percentage:  1 to 10%

Storage: Cool, dry place. Do not freeze. Keep away from light and moisture!
Country of origin: China

Phytosterol Standardized Pre Dissolved Solution - 10%

Assay: 9.5%
CAS#:29806-73-3, 68555-08-8
INCI: Ethyl Hexyl Palmitate, Phytosterols
Appearance: liquid

Solubility: add to cream
Suggested percentage:
11% solution gives 1% Phytosterols content in final product.
32% solution gives 3% Phytosterols content in final product.
53% solution gives 5% Phytosterols content in final product.

Storage: Store in fridge, do not freeze.
Country of origin for raw material: China
Country of manufacture: Taiwan
[1]          B. J. Grattan, “Plant Sterols as Anticancer Nutrients: Evidence for Their Role in Breast Cancer,” Nutrients, vol. 5, no. 2, pp. 359–387, Jan. 2013.
[2]          M. B. Gupta, R. Nath, N. Srivastava, K. Shanker, K. Kishor, and K. P. Bhargava, “Anti-inflammatory and antipyretic activities of beta-sitosterol,” Planta Med., vol. 39, no. 2, pp. 157–163, Jun. 1980.
[3]          E. S. Ang, S. T. Lee, C. S. Gan, P. G. See, Y. H. Chan, L. H. Ng, and D. Machin, “Evaluating the role of alternative therapy in burn wound management: randomized trial comparing moist exposed burn ointment with conventional methods in the management of patients with second-degree burns,” MedGenMed Medscape Gen. Med., vol. 3, no. 2, p. 3, Mar. 2001.
[4]          B. S. Atiyeh, J. Ioannovich, C. A. Al-Amm, K. A. El-Musa, and R. Dham, “Improving scar quality: a prospective clinical study,” Aesthetic Plast. Surg., vol. 26, no. 6, pp. 470–476, Dec. 2002.
[5]          B. S. Atiyeh, K. A. El-Musa, and R. Dham, “Scar quality and physiologic barrier function restoration after moist and moist-exposed dressings of partial-thickness wounds,” Dermatol. Surg. Off. Publ. Am. Soc. Dermatol. Surg. Al, vol. 29, no. 1, pp. 14–20, Jan. 2003.
[6]          A. N. Aziz, H. Ibrahim, D. Rosmy Syamsir, M. Mohtar, J. Vejayan, and K. Awang, “Antimicrobial compounds from Alpinia conchigera,” J. Ethnopharmacol., vol. 145, no. 3, pp. 798–802, Feb. 2013.
[7]          R. Bawankar, V. C. Deepti, P. Singh, R. Subashkumar, G. Vivekanandhan, and S. Babu, “Evaluation of bioactive potential of an Aloe vera sterol extract,” Phytother. Res. PTR, vol. 27, no. 6, pp. 864–868, Jun. 2013.
[8]          S. Rozner, L. Verkhovski, Y. Nissimov, A. Aserin, R. Vilensky, D. Danino, C. C. Zouboulis, Y. Milner, and N. Garti, “Inhibition of cholesterol transport into skin cells in cultures by phytosterol-loaded microemulsion,” Chem. Phys. Lipids, vol. 153, no. 2, pp. 109–118, Jun. 2008.
[9]          L.-H. Chiang, S.-H. Chen, and A.-I. Yeh, “Preparation of nano/submicrometer yam and its benefits on collagen secretion from skin fibroblast cells,” J. Agric. Food Chem., vol. 60, no. 50, pp. 12332–12340, Dec. 2012.
[10]        T. H. Lee, S. M. Lee, D.-Y. Lee, Y. Son, D. K. Chung, N.-I. Baek, and J. Kim, “A glycosidic spinasterol from Koreana stewartia promotes procollagen production and inhibits matrix metalloproteinase-1 expression in UVB-irradiated human dermal fibroblasts,” Biol. Pharm. Bull., vol. 34, no. 5, pp. 768–773, 2011.
[11]        M.-S. Kim, G.-H. Oh, M.-J. Kim, and J.-K. Hwang, “Fucosterol inhibits matrix metalloproteinase expression and promotes type-1 procollagen production in UVB-induced HaCaT cells,” Photochem. Photobiol., vol. 89, no. 4, pp. 911–918, Aug. 2013.
[12]        S. Boller, C. Soldi, M. C. A. Marques, E. P. Santos, D. A. Cabrini, M. G. Pizzolatti, A. R. Zampronio, and M. F. Otuki, “Anti-inflammatory effect of crude extract and isolated compounds from Baccharis illinita DC in acute skin inflammation,” J. Ethnopharmacol., vol. 130, no. 2, pp. 262–266, Jul. 2010.
[13]        N.-R. Han, H.-M. Kim, and H.-J. Jeong, “The β-sitosterol attenuates atopic dermatitis-like skin lesions through down-regulation of TSLP,” Exp. Biol. Med. Maywood NJ, vol. 239, no. 4, pp. 454–464, Apr. 2014.
[14]        K. Yasukawa, M. Takido, T. Matsumoto, M. Takeuchi, and S. Nakagawa, “Sterol and triterpene derivatives from plants inhibit the effects of a tumor promoter, and sitosterol and betulinic acid inhibit tumor formation in mouse skin two-stage carcinogenesis,” Oncology, vol. 48, no. 1, pp. 72–76, 1991.
 
 

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