Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
This is a fantastic product. Highly moisturizing and smooths out lines and wrinkles. It works quickly and is evening out skin tone as well. I think its a must have product and I certainly will be purchasing it again.. ...»
This is a fantastic product. Highly moisturizing and smooths out lines and wrinkles. It works quickly and is evening out skin tone as well. I think its a must have product and I certainly will be purchasing it again.. ...»
This lovely, simple, and affordable product has become something I don't want to be without. I am 47, with very sensitive and reactive dry skin. This cream doesn't feel particularly moisturizing and leaves something of a 'dry' finish on the skin after application, but it's had SUCH a positive impact on my face. The redness and papules from my rosacea and seb derm have reduced by a good 90%. It's been a magical barrier restorer and I panicked when it was temporarily out of stock. I would recomme.. ...»
Candace Carnahan
This is the best product I have ever used on my skin and I tried a LOT of expansive brands. It helps with redness and overall skin tone. Please do not ever stop making this stuff... ...»
I' m not sure about this: "11% solution gives 1% EGCG content in final product." What is the weight of final product? .. ...»
Vesna Hanich
It is true, this product does leave the skin silky smooth! I can highly recommend using it in your masks... ...»
Mati Fuller
I am 69 and I have used this product for two years almost every day at a high dose, adding it to my antioxidant day cream, with excellent results. For me it has a very high quality and effectiveness: reduction of wrinkles, hydrated skin, unified color without blemishes ... A product of 10, the same score that I give to John for the quality of the products he sells, his excellent description / use and the bibliographic contribution.En .. ...»
María Jesus
Tried this on my week-old rash from flea bites. Got an almost instant relief and rash healed in 2 days. Tried it on my daughter who has eczema for a very long time. The rashes calmed down after a few days and her skin is now healing well. Really great product. Just put in order for another jar.... ...»
This is great stuff. I add it to my liquid face soap and it does an excellent job in preventing acne and gently exfoliating the skin... ...»
Really loving this product. I make the best Centella toner and most concentrated ever. 2 g of centella extract dissolved in 10g of alcohol(you have to stir a lot) plus 88 grams of water and you get a very concentrated toner. Creams, toners, ampoules... all have only 0,1% of triterpenes, this toner i make have 1,4%. I am loving it, will see the results. .. ...»
Secure Payments
Orders Securely Processed Through PayPal
 Visa  Mastercard  Discover  American Express

SSL Certificate

As Featured On EzineArticles





Important Stuff

 All customers PLEASE read:

 the FAQ and Delivery Info pages!

Canadian Customers:

Any long delivery delays are caused by The Canada Border Services Agency.
I now ONLY offer EMS as a shipping option to Canada. 
This appears to have resolved most of the delays caused by The Canada Border Services Agency.

Please write your correct address:

We take NO responsibility for delivery issues caused by customers entering the wrong address in the checkout page


BulkActives is a part-time business. Orders are processed and mailed on Saturdays. (TimeZone Order Deadline Chart)

What we sell

We sell  COSMETIC RAW MATERIALS, which are meant to be used at an appropriate percentage in a cosmetic formulation of your devising. Please do not order our products unless you know how to formulate creams and lotions with it!  

Forgotten your password? Not receiving lost password emails? Can't create an account?

NO PROBLEM!  Just email me, and I will sort it all out.

Not receiving order status email updates?

Please check your JUNK mail folder for our emails, and mark them as NOT SPAM.

Failing to do so will result in NOT receiving ANY transaction / order status email updates.

Recipe % calculator


Sample Recipes

Download sample recipes RAR file

Buy Soy Isoflavones For Skin Care

Soy isoflavones are comparatively new in regards to cosmetic use, however, studies show they have multiple skin-benefitting properties.Isoflavones are structurally similar to estrogens and can activate estrogen signaling pathways, including collagen synthesis, to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and increase tissue hydration.Additionally isoflavones are powerful antioxidants that can halt and reverse the appearance of aging due to free radicals caused by sunlight and other environmental hazards.As such, soy isoflavones are useful in reducing redness of the skin and decreasing the appearance of dark spots.These properties make soy isoflavones ideal for use in anti-aging, moisturizing, and skin protecting creams.

Key benefits of Soy isoflavones on skin care:

  • Anti-inflammatory [6, 11, 12]
  • Antioxidant [3, 6]
  • Increase skin elasticity [1, 4, 5, 15]
  • Matrix metalloproteinase [MMP] inhibitors [9]
  • Moisturizing and hydration [5, 15]
  • Natural phytoestrogens [3, 15]
  • Reduce fine lines and wrinkles [1, 4, 5, 15]
  • Stimulate collagen production [1, 4, 5, 15]
  • Sun damage protection [3, 6, 11, 12, 14]
  • Sun damage repair [3, 6, 11, 12, 14]
  • Treat hyperpigmentation [3]
Soy Isoflavones skin care active ingredients
Product Code: BulkActives
Assay: Total Isoflavones 40%
CAS#: 574-12-9
Net weight: 30g /1.06oz
Availability: In Stock
Price: $14.20

    - OR -   Add to Wish List
Add to Compare

Soy Isoflavones

Soy Isoflavones skin careAbout Soy Isoflavones in DIY Skin Care

Aging in post-menopausal women is closely associated with decreased levels of hormones including the female sex hormone estrogen.  Studies of these women indicate that the decrease in estrogen is associated with changes in the skin such as dryness, dermal atrophy, reduced mechanical tension, and the increased appearance of fine lines and wrinkles due to a decline in dermal collagen content [1].  Such changes in the skin are potentiated by photoaging, which results from UV-induced oxidation in the skin.  Damage from UV irradiation can also cause increased expression of matrix metalloproteinases [MMPs] in the skin, including MMP-1, MMP-2, MMP-3, and MMP-9  [2].  These proteinases degrade the collagen network in the skin and thus contribute to the aged appearance. 

Soy isoflavones are phytoestrogens, or plant-derived estrogens, which can bind to estrogen receptors and initiate signaling pathways related to maintaining dermal integrity.  Particularly of interest, soy isoflavones can elicit such responses in the skin but do not increase the risk of uterine or breast cancers unlike most other estrogen replacement therapies [3].  Independently of their estrogen receptor-binding abilities, soy isoflavones are powerful antioxidants capable of neutralizing and reversing photoaging effects [3].

The binding of estrogen to its receptors activates a variety of genes including those involving collagen production.  A clinical study testing isoflavones to reverse the signs of post-menopausal skin aging found that after treatment with an isoflavone-containing cream twice daily for twelve weeks participants had improved skin dryness and roughness by 32.9% and 22%, respectively, compared to untreated skin.  Wrinkles and skin looseness were also significantly reduced by 22% and 24%, respectively [4].   A similar study testing topically applied isoflavones demonstrated a 7.5% increase in the number of collagen fibers after treatment for six months [5].  Additionally, because collagen is capable of binding large amounts of water, it has been suggested that an indirect effect of isoflavone creams is increased hydration of the skin.  This therefore also makes them useful in moisturizing creams.

The skin is highly susceptible to free radical attack caused by environmental elements such as sunlight, cigarette smoke, and pollution, all of which contribute to premature aging of the skin.  Such environmental hazards can increase the rate of collagen degradation in skin, cause dermal inflammation, and lead to pigment abnormalities [3].  The antioxidant properties of isoflavones halt and reverse these effects by neutralizing free radicals.  Studies have demonstrated that isoflavones can impair the formation of free radicals and block oxidative stress-induced apoptosis of epidermal cells [6].  Because free radicals drive melanogenesis, or the hyperpigmentation, in fibroblasts, the antioxidant properties of soy isoflavones are also believed to be able to decrease the appearance of dark spots and even out skin tone [7, 8].

Isoflavones are also known to inhibit tyrosine kinases by competing for the ATP-binding site.  Through this mechanism, isoflavones can decrease MMP levels in the skin while increasing the levels of the body’s natural MMP inhibitors [9, 10].  In human epidermal cell cultures, isoflavones effectively inhibited UV-stimulated tyrosine kinases involved with initiation of inflammation [11, 12].  Thus, isoflavones have the capability to protect the integrity of the dermal matrix and to prevent UV-induced damage to the skin.

Interestingly, because dysregulation of tyrosine kinases and free radicals are each associated with driving carcinogenesis, soy isoflavones have been investigated for use in preventing or slowing skin cancer progression.  Several studies have successfully demonstrated that treatment with isoflavones can reduce the number of skin tumors and slow the rate of growth of skin cancer [13, 14].
CAS#: 574-12-9
INCI: Soy Isoflavones
Botanical Source: Soybean
Appearance: powder
Solubility: water, non-denatured ethanol
Suggested percentage: 3% to 5%

Storage: Store in cool and dry place. Keep away from direct strong light and heat.
Country of origin: China
[1]          Brincat M, Moniz C, Studd J, Darby A, Magos A, Emburey G, et al. Long‐term effects of the menopause and sex hormones on skin thickness. BJOG: An International Journal of Obstetrics & Gynaecology. 1985;92[3]:256-9.
[2]          Fisher GJ, Datta SC, Talwar HS, Wang Z-Q, Varani J, Kang S, et al. Molecular basis of sun-induced premature skin ageing and retinoid antagonism. 1996.
[3]          Pinnell SR. Cutaneous photodamage, oxidative stress, and topical antioxidant protection. Journal of the American Academy of Dermatology. 2003;48[1]:1-22.
[4]          Sator P-G, Schmidt JB, Rabe T, Zouboulis CC. Skin aging and sex hormones in women – clinical perspectives for intervention by hormone replacement therapy. Experimental Dermatology. 2004;13:36-40.
[5]          Accorsi-Neto A, Haidar M, Simões R, Simões M, Soares-Jr J, Baracat E. Effects of isoflavones on the skin of postmenopausal women: a pilot study. Clinics. 2009;64[6]:505-10.
[6]          Chan W-H, Yu J-S. Inhibition of UV irradiation-induced oxidative stress and apoptotic biochemical changes in human epidermal carcinoma A 431 cells by genistein. Journal of cellular biochemistry. 2000;78[1]:73-84.
[7]          Pawelek J, Chakraborty A. The enzymology of melanogenesis. The pigmentary system. 1998:391-400.
[8]          Paine C, Sharlow E, Liebel F, Eisinger M, Shapiro S, Seiberg M. An Alternative Approach to Depigmentation by Soybean Extracts via Inhibition of the PAR-2 Pathway. 2001;116[4]:587-95.
[9]          Puli S, Lai JC, Bhushan A. Inhibition of matrix degrading enzymes and invasion in human glioblastoma [U87MG] cells by isoflavones. Journal of Neuro-oncology. 2006;79[2]:135-42.
[10]        Kousidou OC, Mitropoulou T, Roussidis A, Kletsas D, Theocharis A, Karamanos N. Genistein suppresses the invasive potential of human breast cancer cells through transcriptional regulation of metalloproteinases and their tissue inhibitors. International journal of oncology. 2005;26[4]:1101-9.
[11]        Miller CC, Hale P, Pentland AP. Ultraviolet B injury increases prostaglandin synthesis through a tyrosine kinase-dependent pathway. Evidence for UVB-induced epidermal growth factor receptor activation. Journal of Biological Chemistry. 1994;269[5]:3529-33.
[12]        Isoherranen K, Punnonen K, Jansen C, Uotila P. Ultraviolet irradiation induces cyclooxygenase-2 expression in keratinocytes. British journal of dermatology. 1999;140:1017-22.
[13]        Wei H, Bowen R, Zhang X, Lebwohl M. Isoflavone genistein inhibits the initiation and promotion of two-stage skin carcinogenesis in mice. Carcinogenesis. 1998;19[8]:1509-14.
[14]        Moore JO, Wang Y, Stebbins WG, Gao D, Zhou X, Phelps R, et al. Photoprotective effect of isoflavone genistein on ultraviolet B-induced pyrimidine dimer formation and PCNA expression in human reconstituted skin and its implications in dermatology and prevention of cutaneous carcinogenesis. Carcinogenesis. 2006;27[8]:1627-35.
[15]        Hall G, Phillips TJ. Estrogen and skin: The effects of estrogen, menopause, and hormone replacement therapy on the skin. Journal of the American Academy of Dermatology. 2005;53[4]:555-68.

Write a review

Your Name:

Your Review: Note: HTML is not translated!

Rating: Bad           Good

Enter the code in the box below:

(c) BulkActives 2005-2024