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Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
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- ALL PRODUCTS
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ACTIVES
- - anti-acne
- - anti-androgenetic alopecia
- - anti-bacterial
- - anti-blackheads
- - anti-inflammatory
- - antioxidant
- - capillary health
- - exfoliating
- - glycation inhibitor and repair
- - increase cellular energy production
- - increase skin elasticity
- - lightening and brightening
- - matrix metalloproteinases (MMP) inhibitors
- - moisturizing and hydration
- - natural phyto estrogens
- - nutrition
- - oil/sebum control
- - pore refinement
- - reduce dark circles under the eyes
- - reduce fine lines and wrinkles
- - reduce rosacea
- - restore barrier function
- - scar care
- - stimulate collagen production
- - stimulate HA production
- - sun damage protection
- - sun damage repair
- - treat hyperpigmentation
- - wound healing support
- - wrinkle relaxers
- - wrinkle tighteners
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Reviews
This is the best product I have ever used on my skin and I tried a LOT of expansive brands. It helps with redness and overall skin tone. Please do not ever stop making this stuff... ...»
Helena
I' m not sure about this: "11% solution gives 1% EGCG content in final product." What is the weight of final product? .. ...»
Vesna Hanich
This is great stuff.
I add it to my liquid face soap and it does an excellent job in preventing acne and gently exfoliating the skin... ...»
Marie
Just recently ordered this and LOVE! Green Tea EGCG truly is one of the most fantastic skincare actives out there. Very difficult to find good quality product (90%) and even harder to actually solubilize it! Love that it comes in pre-dissolved solution. I enjoy adding it at 1% (so 11% sol) to my serum formulations containing Niacinamide 5% + NAG 3%. Excellent for oily acne prone skin.
*Only gripe... because the Pre-Dissolved Solution is SO heavy in propanediol (10 parts Propanediol for 1 part E.. ...»
Victor
Very good product. It performed exactly how I expected. .. ...»
Ryan
This ingredient has done more for my skin than anything else I've ever used.
I put it into a spray facial toner and use it morning and night. I noticed the effects immediately, they were that dramatic.
I will use this forever, no question... ...»
Marie
I've been using Bulkactives green tea EGCG for four years. No complaints, it blends nicely my DIY anti-aging cream. I can feel a bit of toning and definitely notice the anti-inflammatory effects on my skin. Two observations that keep the rating 4 stars instead of 5: (1) A package of green tea contains significantly less weight/volume than the package of grape seed extract that I order from bulkactives. The two are combined in equal amounts in the anti-aging cream, so I find myself running o.. ...»
Theresa Andrews
This is the best product I have ever used on my skin and I tried a LOT of expansive brands. It helps with redness and overall skin tone. Please do not ever stop making this stuff... ...»
Helena
I' m not sure about this: "11% solution gives 1% EGCG content in final product." What is the weight of final product? .. ...»
Vesna Hanich
It is true, this product does leave the skin silky smooth! I can highly recommend using it in your masks... ...»
Mati Fuller
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Important Stuff
All customers PLEASE read:
the FAQ and Delivery Info pages!
Canadian Customers:
Any long delivery delays are caused by The Canada Border Services Agency.
I now ONLY offer EMS as a shipping option to Canada.
This appears to have resolved most of the delays caused by The Canada Border Services Agency.
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BulkActives is a part-time business. Orders are processed and mailed on Saturdays. (TimeZone Order Deadline Chart)
What we sell
We sell COSMETIC RAW MATERIALS, which are meant to be used at an appropriate percentage in a cosmetic formulation of your devising. Please do not order our products unless you know how to formulate creams and lotions with it!
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Due to Wuhan Pneumonia Virus (aka Covid-19) border restrictions and a reduction or cancellation of flights by airlines, we CAN ONLY ship to the counries listed below!
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UK customers, we are finally ABLE to ship to the UK.
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IMPORTANT: If your country is NOT in the above lists, then we CANNOT ship to you at the moment.
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Buy Carnitine (L-Carnitine) For Skin Care
Carnitine is a naturally occurring substance, necessary for fat and glucose metabolism in human body cells. Primary function of carnitine in pharmacy is the reduction of advanced glycation end products (AGEs). AGEs are proteins, damaged by reactions with sugars, therefore glycation is most prominent in diabetes patients. It also occurs in many other diseases, as well as natural ageing processes. Dermal carnitine applications reduce the level of glycated collagen and promote synthesis of new protein. Since it is involved in lipid metabolism, carnitine is used for acne treatment. It effectively reduces sebum secretion and skin oiliness. Carnitine preparations also improve other aspects of the skin, such as tonicity, and reduce cellulite. Finally, it aids skin regeneration after damage, such as burns, and promotes blood vessel formation. Regretably, due to Candian law and PayPal regulations, this product may NOT be shipped to Canada.
Key beneftis of Carnitine in skin care:
- Oil/sebum control [4] [5]
- Glycation inhibition and repair [1] [3]
- Increase cellular energy production [1] [3]
- Anti-acne [5]
- Restore barrier function [6] [7]
- Wound-healing support [8]
Product Code: BulkActives
Assay: 99%
CAS#: 3040-38-8
Net weight: 30g /1.06oz
Availability: Product Out Of Stock
Assay: 99%
CAS#: 3040-38-8
Net weight: 30g /1.06oz
Availability: Product Out Of Stock
Price: $6.41
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Carnitine (L-Carnitine)
About L Carnitine in DIY Skin Care
Carnitine (also L-carnitine or CA) is a naturally occurring substance, necessary for the cellular metabolism of glucose, fat and related compounds. Since these metabolic processes occur in most cells of the body, carnitine deficiency is associated with a wide range of diseases, such as muscle weakness, cardiac hypertrophy and accelerated atherosclerosis [1], [2]. Most importantly, carnitine helps to reduce protein glycation levels.Glycation is a detrimental protein change that occurs in typical ageing processes. It involves a non-specific reaction between various sugars and proteins, especially collagen [3]. The damage brought on by such reactions is irreversible and results in dysfunctional protein aggregates, called advanced glycation end products (AGEs). AGE formation proceeds faster under elevated blood sugar levels, typically caused by diabetes, but they are also involved in the development of other disorders, among them osteoporosis, Alzheimer’s disease and cancer [1]. Carnitine was shown to be successful at inhibiting collagen glycation in rats that were fed on a high-sugar diet [3].
Furthermore, it reduced the AGE levels even more than commercially used antiglycation agent aminoguanidine, and also enhanced glucose metabolism in the diaphragm. Research on humans also confirms this conclusion, indicating that carnitine successfully reduces AGE levels in skin [1]. It is even suggested for management of adverse chemo- and radiotherapy effects. Recent studies have found that carnitine reduces therapy-caused damage to various organs and possibly even fatigue from chemotherapy [2].
In skin care, carnitine is a favored ingredient for several purposes.
Due to its role in lipid metabolism, it is known to inhibit sebum secretion and thus reduce skin oiliness. Applying 2 %-carnitine containing cream for 3 weeks was enough to significantly reduce both lipid content and sebum production in human sebaceous glands [4]. The same effect is utilized in anti-acne preparations with carnitine. In a study of mild to moderately severe acne, volunteers used a face cleanser with carnitine for 8 weeks. Total lesion count, sebum production, bacterial colonization, were all reduced; pustule count decreased 5 times, and general life quality of the subjects (measured by a questionnaire test) was improved [5].Carnitine can also improve skin appearance in other ways. It is involved in skin cell proliferation, as it was shown to increase epidermal thickness both in healthy skin and during regeneration after wounds [6], [7]. Using a carnitine-containing preparation for 12 weeks resulted in various esthetic improvements of the skin, such as decreased cellulite and improved tonicity [6]. It is also known to promote wound healing, likely due to increased collagen synthesis, skin cell migration or energy release [7]–[9]. This effect is especially important in patients using steroids, as these medications can reduce the activity of immune processes necessary for wound healing [8]. The healing process can also be disrupted by diabetes, but preparations containing carnitine were effective in such models as well, promoting skin regeneration and faster healing [9]. Benefits of carnitine are not limited to simple wounds – larger burns were also investigated. Carnitine successfully reduced tissue necrosis, promoted cell proliferation, and increased the formation of new blood vessels [10], [11]. The positive effects on skin cells is enhanced even more when carnitine is combined with retinol (a form of vitamin A) or vitamin C [6], [10].
Carnitine exists in two forms: L-Carnitine and D-Carnitine. Only the L-Carnitine form is desirous as the D-Carnitine form is physiologically inactive and can inhibit the uptake and functions of the natural isomer L-Carnitine. BulkActives' Carnitine is L carnitine.
Assay: 99%
CAS#: 3040-38-8
INCI: Acetyl Carnitine
Appearance: white powder
Solubility: water, Dimethyl isosorbide
Suggested percentage: 2%
Storage: Keep tightly closed, in cool place. Hygroscopic.
Country of origin: China
CAS#: 3040-38-8
INCI: Acetyl Carnitine
Appearance: white powder
Solubility: water, Dimethyl isosorbide
Suggested percentage: 2%
Storage: Keep tightly closed, in cool place. Hygroscopic.
Country of origin: China
[1] K. Fukami, S.-I. Yamagishi, K. Sakai, Y. Kaida, T. Adachi, R. Ando, and S. Okuda, “Potential inhibitory effects of L-carnitine supplementation on tissue advanced glycation end products in patients with hemodialysis,” Rejuvenation Res., vol. 16, no. 6, pp. 460–466, Dec. 2013.
[2] H. A. Khan and A. S. Alhomida, “A review of the logistic role of L-carnitine in the management of radiation toxicity and radiotherapy side effects,” J. Appl. Toxicol. JAT, vol. 31, no. 8, pp. 707–713, Nov. 2011.
[3] P. Rajasekar and C. V. Anuradha, “L-Carnitine inhibits protein glycation in vitro and in vivo: evidence for a role in diabetic management,” Acta Diabetol., vol. 44, no. 2, pp. 83–90, Jun. 2007.
[4] R. I. Peirano, T. Hamann, H.-J. Düsing, M. Akhiani, U. Koop, T. Schmidt-Rose, and H. Wenck, “Topically applied L-carnitine effectively reduces sebum secretion in human skin,” J. Cosmet. Dermatol., vol. 11, no. 1, pp. 30–36, Mar. 2012.
[5] I. Angelova-Fischer, F. Rippke, T. W. Fischer, G. Neufang, and D. Zillikens, “A double-blind, randomized, vehicle-controlled efficacy assessment study of a skin care formulation for improvement of mild to moderately severe acne,” J. Eur. Acad. Dermatol. Venereol. JEADV, vol. 27 Suppl 2, pp. 6–11, Jul. 2013.
[6] R. Roure, T. Oddos, A. Rossi, F. Vial, and C. Bertin, “Evaluation of the efficacy of a topical cosmetic slimming product combining tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol, In vitro, ex vivo and in vivo studies,” Int. J. Cosmet. Sci., vol. 33, no. 6, pp. 519–526, Dec. 2011.
[7] T. Karsidag, J. A. Asensio, F. Kabukcuoglu, and S. Tuzun, “Preliminary study comparing the effects of locally and systemically applied L-carnitine on the healing of full-thickness skin defects,” Scand. J. Surg. SJS Off. Organ Finn. Surg. Soc. Scand. Surg. Soc., vol. 99, no. 3, pp. 147–152, 2010.
[8] A. Akkus, K. Aydinuraz, C. Daphan, O. Saygun, O. Caglayan, M. Edremitlioglu, and F. Agalar, “Effect of carnitine on cutaneous wound healing in immunosuppressed rats,” J. Surg. Res., vol. 155, no. 2, pp. 301–305, Aug. 2009.
[9] L. Gennero, R. De Siena, T. Denysenko, M. A. Roos, G. F. Calisti, M. Martano, S. Fiobellot, M. Panzone, S. Reguzzi, L. Gabetti, A. Vercelli, G. Cavallo, E. Ricci, and G. P. Pescarmona, “A novel composition for in vitro and in vivo regeneration of skin and connective tissues,” Cell Biochem. Funct., vol. 29, no. 4, pp. 311–333, Jun. 2011.
[10] E. Arslan, Y. Basterzi, A. Aksoy, C. Majka, S. Unal, A. Sari, and F. Demirkan, “The additive effects of carnitine and ascorbic acid on distally burned dorsal skin flap in rats,” Med. Sci. Monit. Int. Med. J. Exp. Clin. Res., vol. 11, no. 6, pp. BR176–180, Jun. 2005.
[11] E. Arslan, A. Milcan, S. Unal, F. Demirkan, A. Polat, O. Bagdatoglu, A. Aksoy, and G. Polat, “The effects of carnitine on distally-burned dorsal skin flap: an experimental study in rats,” Burns J. Int. Soc. Burn Inj., vol. 29, no. 3, pp. 221–227, May 2003.
[2] H. A. Khan and A. S. Alhomida, “A review of the logistic role of L-carnitine in the management of radiation toxicity and radiotherapy side effects,” J. Appl. Toxicol. JAT, vol. 31, no. 8, pp. 707–713, Nov. 2011.
[3] P. Rajasekar and C. V. Anuradha, “L-Carnitine inhibits protein glycation in vitro and in vivo: evidence for a role in diabetic management,” Acta Diabetol., vol. 44, no. 2, pp. 83–90, Jun. 2007.
[4] R. I. Peirano, T. Hamann, H.-J. Düsing, M. Akhiani, U. Koop, T. Schmidt-Rose, and H. Wenck, “Topically applied L-carnitine effectively reduces sebum secretion in human skin,” J. Cosmet. Dermatol., vol. 11, no. 1, pp. 30–36, Mar. 2012.
[5] I. Angelova-Fischer, F. Rippke, T. W. Fischer, G. Neufang, and D. Zillikens, “A double-blind, randomized, vehicle-controlled efficacy assessment study of a skin care formulation for improvement of mild to moderately severe acne,” J. Eur. Acad. Dermatol. Venereol. JEADV, vol. 27 Suppl 2, pp. 6–11, Jul. 2013.
[6] R. Roure, T. Oddos, A. Rossi, F. Vial, and C. Bertin, “Evaluation of the efficacy of a topical cosmetic slimming product combining tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol, In vitro, ex vivo and in vivo studies,” Int. J. Cosmet. Sci., vol. 33, no. 6, pp. 519–526, Dec. 2011.
[7] T. Karsidag, J. A. Asensio, F. Kabukcuoglu, and S. Tuzun, “Preliminary study comparing the effects of locally and systemically applied L-carnitine on the healing of full-thickness skin defects,” Scand. J. Surg. SJS Off. Organ Finn. Surg. Soc. Scand. Surg. Soc., vol. 99, no. 3, pp. 147–152, 2010.
[8] A. Akkus, K. Aydinuraz, C. Daphan, O. Saygun, O. Caglayan, M. Edremitlioglu, and F. Agalar, “Effect of carnitine on cutaneous wound healing in immunosuppressed rats,” J. Surg. Res., vol. 155, no. 2, pp. 301–305, Aug. 2009.
[9] L. Gennero, R. De Siena, T. Denysenko, M. A. Roos, G. F. Calisti, M. Martano, S. Fiobellot, M. Panzone, S. Reguzzi, L. Gabetti, A. Vercelli, G. Cavallo, E. Ricci, and G. P. Pescarmona, “A novel composition for in vitro and in vivo regeneration of skin and connective tissues,” Cell Biochem. Funct., vol. 29, no. 4, pp. 311–333, Jun. 2011.
[10] E. Arslan, Y. Basterzi, A. Aksoy, C. Majka, S. Unal, A. Sari, and F. Demirkan, “The additive effects of carnitine and ascorbic acid on distally burned dorsal skin flap in rats,” Med. Sci. Monit. Int. Med. J. Exp. Clin. Res., vol. 11, no. 6, pp. BR176–180, Jun. 2005.
[11] E. Arslan, A. Milcan, S. Unal, F. Demirkan, A. Polat, O. Bagdatoglu, A. Aksoy, and G. Polat, “The effects of carnitine on distally-burned dorsal skin flap: an experimental study in rats,” Burns J. Int. Soc. Burn Inj., vol. 29, no. 3, pp. 221–227, May 2003.
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