Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
This is the best product I have ever used on my skin and I tried a LOT of expansive brands. It helps with redness and overall skin tone. Please do not ever stop making this stuff... ...»
I am 69 and I have used this product for two years almost every day at a high dose, adding it to my antioxidant day cream, with excellent results. For me it has a very high quality and effectiveness: reduction of wrinkles, hydrated skin, unified color without blemishes ... A product of 10, the same score that I give to John for the quality of the products he sells, his excellent description / use and the bibliographic contribution.En .. ...»
Really loving this product. I make the best Centella toner and most concentrated ever. 2 g of centella extract dissolved in 10g of alcohol(you have to stir a lot) plus 88 grams of water and you get a very concentrated toner. Creams, toners, ampoules... all have only 0,1% of triterpenes, this toner i make have 1,4%. I am loving it, will see the results. .. ...»
Just recently ordered this and LOVE! Green Tea EGCG truly is one of the most fantastic skincare actives out there. Very difficult to find good quality product (90%) and even harder to actually solubilize it! Love that it comes in pre-dissolved solution. I enjoy adding it at 1% (so 11% sol) to my serum formulations containing Niacinamide 5% + NAG 3%. Excellent for oily acne prone skin.
*Only gripe... because the Pre-Dissolved Solution is SO heavy in propanediol (10 parts Propanediol for 1 part E.. ...»
Carla, Many medications can be and are applied topically by prescription. With that in mind, realize that this particular ingredient is wonderful but understand that this is indeed one of those that may create sensitivity with those already using topical hormones or just use sparingly and see how you respond. Sorry for the very late response..... ...»
muy satisfecho
profesionales,
y envio sin problemas ,ya que soy de españa
producto bien envasado ,
un placer ser cliente
porque dan comnfianza y calidad.gracias un saludo.. ...»
Any long delivery delays are caused by The Canada Border Services Agency.
I now ONLY offer EMS as a shipping option to Canada.
This appears to have resolved most of the delays caused by The Canada Border Services Agency.
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We take NO responsibility for delivery issues caused by customers entering the wrong address in the checkout page
We sell COSMETIC RAW MATERIALS, which are meant to be used at an appropriate percentage in a cosmetic formulation of your devising. Please do not order our products unless you know how to formulate creams and lotions with it!
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BulkActives has been in business since 2005, we might have disappeared from google search results, but we're still hanging on, just, mainly thanks to the support of some loyal customers.
However, like many, COVID hit us hard, and we're having a lot of trouble recovering.
Right now, we have not restocked many powders, however, are looking at continuing with selling only our flagship products:
seakelp and pre-dissolved powders, and some of the essentials.
Ginkgo biloba is a unique tree species. Its leaf extract contains a diverse variety of molecules useful in cosmetics and pharmacology. Firstly, they are potent antioxidants, and can even activate the production of enzymes that neutralize free radicals. Combined with the anti-inflammatory effects, this extract provides an effective defense against UV radiation and ageing symptoms. Dermal applications of this extract can even lead to protection of other organs. Another major application of Ginkgo biloba is moisturizing the skin, which helps to increase its elasticity and visual appearance, even reducing the amount of wrinkles. Furthermore, this extract helps to maintain the barrier function of the skin – it reduces water loss through epidermis, thus reducing skin dryness and irritation. In combination with green tea extract, Ginkgo shows even stronger benefits in these areas.
NOTE: To assist you with solubility issues, we now also sell Ginkgo Biloba extract as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.
Ginkgo biloba is a unique tree with no close living relatives. An extract produced from its leaves has a large variety of molecules, but most health benefits are associated with two groups – terpene trilactones and flavonoid glycosides. These molecules are potent antioxidants and have numerous other effects: they improve blood flow, protect against capillary fragility, function as anti-inflammatory agents, reduce edema caused by tissue injury, and neutralize free radicals [1]. The same two groups of molecules, together with another one called biflavones, have most promising uses in cosmetics, ranging from simple effects in moisturizing to radiation protection and anti-ageing activity [2].
Skin dryness and irritation can be prevented by helping the skin maintain its barrier function. This is one of the main application of Ginkgo in cosmetics. Even a single application of 1.5%-Ginkgo extract containing cream was enough to improve the barrier properties for 8 hours [3]. Moisturizing and hydrating effects were also observed, together with reduced number and width of wrinkles. Furthermore, longer application of the cream led to thicker epidermis, reducing water loss and additionally helping the barrier function of the skin [3]. Epidermal thickening, higher elasticity and improved skin relief were also observed in another study, proving that the hydrating effect of Ginkgo extract extends to the deeper layers of the skin [2]. Compared to several other extracts investigated, Ginkgo has the strongest effect in moisturizing the skin. Using a cream containing 0.3 % of this extract for 1 month showed various benefits for the skin of volunteers, among them an increase in skin smoothness and reduction of wrinkles [4].
Skin as a barrier is also easily damaged by UV radiation, causing increased water loss and erythema. A cream containing 6 % Ginkgo biloba extract was able to completely negate this damage in mice; it also significantly reduced the number of damaged cells [5]. It is suggested that this result stems from strong antioxidant properties of Ginkgo biloba flavonoids – these molecules protect the skin from free radicals formed under UV [1], [6]. Additionally, this extract can counter the effects of UV radiation by increasing the levels of enzymes that neutralize free radicals [7]. Surprisingly, this effect is not limited to skin, as dermal application of Ginkgo extract in mice resulted in increased liver, heart and kidney protection [8]. Another study found that this extract can reduce UV damage on the biochemical level (interferes with inflammatory signals), improve the physiological parameters of the skin, and even reduce the amount of course wrinkles [9].
This antioxidant effect of Ginkgo biloba extends even to cancer prevention. Ginkgo extract can achieve this by neutralizing free radicals, helping to repair damaged DNA, and even promoting cancer cells to undergo apoptosis (cell “suicide”), while leaving healthy cells undamaged [10]. It is even suggested as a protective measure for patients undergoing procedures that involve UV exposure, or to prevent the development of radiation-induced dermatitis [10], [11].
Ginkgetin, one of the biflavone compounds found in Ginkgo biloba, has additional health benefits. It effectively reduced skin inflammation in animal models after just several days of usage [12]. Similar results were found in experiments with human skin cells [13]. Furthermore, Ginkgo biloba extract helps regulate blood flow in skin capillaries, which is especially useful during inflammation [6], [14].
While the dermal use of many beneficial substances is limited by their poor absorption through skin, Ginkgo biloba extract penetrates the epidermis well and is an effective ingredient in cosmetics [15]. It is also resistant to degradation – a cream containing Ginkgo extract was found to be more stable compared to creams with tea and soybean extracts [4]. However, a combination of these compounds (especially Ginkgo and green tea) is advised, as it has greater activity than application of both components separately. Furthermore, each extract treats different aspects of skin damage, therefore underlining the need for combined use [2], [5].
NOTE: To assist you with solubility issues, we now also sell Ginkgo Biloba extract as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.
Ginkgo Biloba extract Standardized Powder
Assay: 99% Ginkgo Biloba Extract (Flavones 24%, Terpene Lactones 6%) CAS#: 90045-36-6 INCI: Ginkgo Biloba Leaf Extract Botanical source: Ginkgo Biloba Leaf Extract is an extract of the leaves of Ginkgo biloba, Ginkgoaceae Appearance: powder Solubility: 1,3-Propanediol Suggested percentage: 1 to 5%
Storage: Store in cool and dry place. Keep away from direct strong light and heat. Country of origin: China
Ginkgo Biloba extract Standardized Pre Dissolved Solution - 10%
Solubility: add to cream Suggested percentage:
11% solution gives 1% Ginkgo Biloba Extract content in final product.
31% solution gives 3% Ginkgo Biloba Extractcontent in final product.
51% solution gives 5% Ginkgo Biloba Extract content in final product.
Storage: Store in fridge, do not freeze Country of origin for raw material: China Country of manufacture: Taiwan
[1] P.-C. Chan, Q. Xia, and P. P. Fu, “Ginkgo Biloba Leave Extract: Biological, Medicinal, and Toxicological Effects,” J. Environ. Sci. Health Part C, vol. 25, no. 3, pp. 211–244, Sep. 2007.
[2] P. M. B. G. M. Campos, M. D. Gianeti, D. G. Mercurio, and L. R. Gaspar, “Synergistic effects of green tea and ginkgo biloba extracts on the improvement of skin barrier function and elasticity,” J. Drugs Dermatol. JDD, vol. 13, no. 9, pp. 1092–1097, Sep. 2014.
[3] M. D. Gianeti and P. M. B. G. Maia Campos, “Efficacy evaluation of a multifunctional cosmetic formulation: the benefits of a combination of active antioxidant substances,” Mol. Basel Switz., vol. 19, no. 11, pp. 18268–18282, 2014.
[4] P. Chuarienthong, N. Lourith, and P. Leelapornpisid, “Clinical efficacy comparison of anti-wrinkle cosmetics containing herbal flavonoids,” Int. J. Cosmet. Sci., vol. 32, no. 2, pp. 99–106, Apr. 2010.
[5] S. E. Dal Belo, L. R. Gaspar, and P. M. B. G. Maia Campos, “Photoprotective effects of topical formulations containing a combination of Ginkgo biloba and green tea extracts,” Phytother. Res. PTR, vol. 25, no. 12, pp. 1854–1860, Dec. 2011.
[6] J. Hibatallah, C. Carduner, and M. C. Poelman, “In-vivo and in-vitro assessment of the free-radical-scavenger activity of Ginkgo flavone glycosides at high concentration,” J. Pharm. Pharmacol., vol. 51, no. 12, pp. 1435–1440, Dec. 1999.
[7] A. Aricioglu, M. Bozkurt, B. Balabanli, M. Kilinç, N. K. Nazaroglu, and N. Türközkan, “Changes in zinc levels and superoxide dismutase activities in the skin of acute, ultraviolet-B-irradiated mice after treatment with ginkgo biloba extract,” Biol. Trace Elem. Res., vol. 80, no. 2, pp. 175–179, May 2001.
[8] S. Y. Lin and H. P. Chang, “Induction of superoxide dismutase and catalase activity in different rat tissues and protection from UVB irradiation after topical application of Ginkgo biloba extracts,” Methods Find. Exp. Clin. Pharmacol., vol. 19, no. 6, pp. 367–371, Aug. 1997.
[9] C.-C. Chen, A.-N. Chiang, H.-N. Liu, and Y.-T. Chang, “EGb-761 prevents ultraviolet B-induced photoaging via inactivation of mitogen-activated protein kinases and proinflammatory cytokine expression,” J. Dermatol. Sci., vol. 75, no. 1, pp. 55–62, Jul. 2014.
[10] R. Eli and J. A. Fasciano, “An adjunctive preventive treatment for cancer: ultraviolet light and ginkgo biloba, together with other antioxidants, are a safe and powerful, but largely ignored, treatment option for the prevention of cancer,” Med. Hypotheses, vol. 66, no. 6, pp. 1152–1156, 2006.
[11] E. Yirmibesoglu, E. Karahacioglu, D. Kilic, N. Lortlar, G. Akbulut, and S. Omeroglu, “The protective effects of Ginkgo biloba extract (EGb-761) on radiation-induced dermatitis: an experimental study,” Clin. Exp. Dermatol., vol. 37, no. 4, pp. 387–394, Jun. 2012.
[12] H. Lim, K. H. Son, H. W. Chang, S. S. Kang, and H. P. Kim, “Effects of anti-inflammatory biflavonoid, ginkgetin, on chronic skin inflammation,” Biol. Pharm. Bull., vol. 29, no. 5, pp. 1046–1049, May 2006.
[13] S. Trompezinski, M. Bonneville, I. Pernet, A. Denis, D. Schmitt, and J. Viac, “Gingko biloba extract reduces VEGF and CXCL-8/IL-8 levels in keratinocytes with cumulative effect with epigallocatechin-3-gallate,” Arch. Dermatol. Res., vol. 302, no. 3, pp. 183–189, Apr. 2010.
[14] E. Boelsma, R.-J. A. N. Lamers, H. F. J. Hendriks, J. H. J. van Nesselrooij, and L. Roza, “Evidence of the regulatory effect of Ginkgo biloba extract on skin blood flow and study of its effects on urinary metabolites in healthy humans,” Planta Med., vol. 70, no. 11, pp. 1052–1057, Nov. 2004.
[15] S. E. dal Belo, L. R. Gaspar, P. M. B. G. Maia Campos, and J.-P. Marty, “Skin penetration of epigallocatechin-3-gallate and quercetin from green tea and Ginkgo biloba extracts vehiculated in cosmetic formulations,” Skin Pharmacol. Physiol., vol. 22, no. 6, pp. 299–304, 2009.
BulkActives are DIY skin care suppliers of skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and standardized botanical extracts for diy skin care products and homemade cosmetics.
DISCLAIMER
We do NOT sell ready-made skin care products!
All our products are powders, liquids, flakes or gels, used for making your own skin care products.
All our products are cosmetic / technical grade only.
We do NOT sell pharmaceuticals, prescription drugs or nutritional supplements.
Any statements about our products have not been evaluated by the FDA.
Our active skin care ingredients are not intended to diagnose, treat, cure, or prevent any disease
SHIPPING
Please write your correct address:
We take NO responsibility for delivery issues caused by customers entering the wrong address in the checkout page
Delivery
BulkActives is a part-time business. Orders are processed and mailed on Saturdays.
Canadian Customers:
Any long delivery delays are caused by The Canada Border Services Agency.
I now ONLY offer EMS as a shipping option to Canada.
This appears to have resolved most of the delays caused by The Canada Border Services Agency.