Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
Reviews
This lovely, simple, and affordable product has become something I don't want to be without. I am 47, with very sensitive and reactive dry skin. This cream doesn't feel particularly moisturizing and leaves something of a 'dry' finish on the skin after application, but it's had SUCH a positive impact on my face. The redness and papules from my rosacea and seb derm have reduced by a good 90%. It's been a magical barrier restorer and I panicked when it was temporarily out of stock. I would recomme.. ...»
Candace Carnahan
This is the best product I have ever used on my skin and I tried a LOT of expansive brands. It helps with redness and overall skin tone. Please do not ever stop making this stuff... ...»
Helena
I' m not sure about this: "11% solution gives 1% EGCG content in final product." What is the weight of final product? .. ...»
Vesna Hanich
Tried this on my week-old rash from flea bites. Got an almost instant relief and rash healed in 2 days. Tried it on my daughter who has eczema for a very long time. The rashes calmed down after a few days and her skin is now healing well. Really great product. Just put in order for another jar.... ...»
Eliz
Just recently ordered this and LOVE! Green Tea EGCG truly is one of the most fantastic skincare actives out there. Very difficult to find good quality product (90%) and even harder to actually solubilize it! Love that it comes in pre-dissolved solution. I enjoy adding it at 1% (so 11% sol) to my serum formulations containing Niacinamide 5% + NAG 3%. Excellent for oily acne prone skin. *Only gripe... because the Pre-Dissolved Solution is SO heavy in propanediol (10 parts Propanediol for 1 part E.. ...»
Victor
Wonderful base cream! Only multi-lamellar structured cream I've found on the market. Cream itself is lightweight (no oil) yet very conditioning/hydrating. Easily accepts water-soluble active ingredients as well as oil-soluble ones. I've even pushed the additional ingred % up to 20 (meaning 80% this cream, 20% added) without any separation issues. Ideal base cream for delivering actives. Personal favorite recipe calls for 5% straight Grapeseed Oil with 5% SebumREG oil active + Panthenol 1% + E Ac.. ...»
Vic
This ingredient has done more for my skin than anything else I've ever used. I put it into a spray facial toner and use it morning and night. I noticed the effects immediately, they were that dramatic. I will use this forever, no question... ...»
Marie
Excellent base Ceramide 2, 3, 6II Lamellar Liquid Crystal PRE emulsion! It went very well for me and my daughter, she has atopic dermatitis. Literally on the third day of applying the cream (which is made up of Multi Lamellar Base Cream V2 Carrier Oil Free, NO Polymer 60%, 10% black currant oil, rice bran oil 5%, 1% of the complex of ceramides and water), the skin of my daughter got clean and healthy. I have noticeably narrowed pores, face was moist and disappeared on my forehead shine. Now Mul.. ...»
Lidia
I've been using Bulkactives green tea EGCG for four years. No complaints, it blends nicely my DIY anti-aging cream. I can feel a bit of toning and definitely notice the anti-inflammatory effects on my skin. Two observations that keep the rating 4 stars instead of 5: (1) A package of green tea contains significantly less weight/volume than the package of grape seed extract that I order from bulkactives. The two are combined in equal amounts in the anti-aging cream, so I find myself running o.. ...»
Theresa Andrews
Another great find on bulkactives. Mixed with de mineralized water, you have the basis to add to any serum, mix with your moisturiser, to simply use on it's own. Love it... ...»
Jan
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Near The End

BulkActives has been in business since 2005, we might have disappeared from google search results, 

but we're still hanging on, just, mainly thanks to the support of some loyal customers.

However, like many, COVID hit us hard, and we're having a lot of trouble recovering.

Right now, we have not restocked many powders, however, are looking at continuing with selling only our flagship products:

seakelp and pre-dissolved powders, and some of the essentials.

Buy Niacinamide (Vitamin B3) For Skin Care

Niacinamide, also known as nicotinamide, is a water soluble form of vitamin B3. Vitamin B3 is essential for maintaining skin health. Niacinamide increases production of important skin structural components such as collagen, ceramide, and keratin. This helps increase moisture and strengthen skin. Niacinamide is known to decrease hyperpigmentation, effectively lightening and brightening skin, especially when used together with n-acetyl glucosamine, a hyaluronic acid precursor. It reduces wrinkles and again, this effect is better with n-acetyl glucosamine. Niacinamide also effectively helps reduce acne and heal wounds. It has anti-oxidant and anti-inflammatory properties. Overall, niacinamide is a compound with many different uses that can increase overall skin health.

Key benefits of Niacinamide in skin care:

  • Treat hyperpigmentation [3] [7] [8]
  • Lightening and brightening [3] [7] [8]
  • Reduce fine lines and wrinkles [9]
  • Anti-inflammatory [5] [6] [8]
  • Anti-oxidant [10] [13]
  • Anti-acne [1] [5] [11]
  • Moisturizing and hydration [2] [5] [12]
  • Restore barrier function [2] [5] [12]
  • Wound healing support [5] [6]
  • Increase skin elasticity [5] [9]
  • Oil/sebum control [2]
  • Pore refinement [2]
  • Sun damage repair [13]
  • Sun damage protection [10]
  • Stimulate collagen production [5]
  • Stimulate HA production [9]
Niacinamide (Vitamin B3) skin care active ingredients
Product Code: BulkActives
Assay: 99%
CAS#: 98-92-0
Net weight: 30g /1.06oz
Availability: In Stock
Price: $6.60


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Niacinamide (Vitamin B3)

About Niacinamide in DIY Skin Care

Niacinamide, also known as nicotinamide, is water soluble vitamin B3 [5]. Vitamin B3 is essential for maintaining the overall health of skin. Vitamin B3 deficiency causes excessive dryness, skin lesions, and sensitivity to sunlight. Niacinamide is a precursor to coenzymes nicotinamide adenine dinucleotide [NAD] and nicotinamide adenine dinucleotide phosphate [NADP]. These are important for many reactions in the body, including those that happen in the skin. NADPH, the hydrogenated form of NADP, is reported to decrease with age [2]. Treatment with niacinamide increases NADP in aged fibroblasts [collagen producing cells] [10]. Thus, niacinamide helps maintain normal amounts of these coenzymes in the skin. Niacinamide is suitable for topical use, as it penetrates easily [5]. It is water soluble and thus, easily used in formulations, and stable. It is tolerated by skin in high concentrations [10].

Niacinamide stimulates ceramide and fatty acid production, major components of skin that provide barrier function [12]. Topical niacinamide stabilizes skin barrier function and reduces moisture loss [5]. A clinical study using topical niacinamide showed it reduces symptoms of dry skin [12]. Topical niacinamide applied to aging skin improves skin surface structure and smoothes out wrinkles [5]. It also reduces skin yellowing, red facial blotches, and pore size by reducing sebum [oil] excretion [1].

Niacinamide also helps reduce hyperpigmentation. Hyperpigmentation involves age spots that are clusters of melanin. Researchers believe niacinamide reduces hyperpigmentation by inhibiting the transfer of cell compartments called melanosomes that store melanin [7]. In clinical studies, topical 4% niacinamide inhibits pigmentation [7, 8]. A greater effect was seen when combined with 2% n-acetyl glucosamine, a hyaluronic acid precursor [3, 7]. Both have different mechanisms of reducing pigmentation, so, used together, they produce a better result.

Niacinamide has great potential as an anti-aging treatment. It has shown to increase keratin synthesis [5]. Keratin is an important structural protein in the skin and levels decrease with age. This reduces the structural soundness of skin and water binding capabilities. Overall, niacinamide stimulates cell growth, including collagen [5]. Collagen is another important structural component of the skin that helps maintain elasticity and plays a role in wound healing. Niacinamide is also a cofactor in hyaluronic acid synthesis [9]. Hyaluronic acid is important for retaining moisture in the skin and protecting barrier function. Levels are known to decrease with age, contributing to wrinkle formation. Thus, increasing hyaluronic acid improves skin elasticity and smoothness. An in vitro study shows 4% niacinamide increases hyaluronic acid. Women using a 2% NAG and 4% niacinamide combined showed improved fine lines and wrinkles, especially under the eyes [9]. This shows the anti-aging effects of niacinamide are best when combined with n-acetyl glucosamine.

It also has anti-inflammatory effects [5]. A clinical study using niacinamide showed reduced rosacea symptoms [4]. It also improved facial skin barrier. In a clinical study, niacinamide also reduced immune cell infiltration that promotes inflammation [8]. Topical 4% niacinamide increased cell growth and helped heal skin lesions [6]. It also reduced acne similar to 1% clindamycin, a common topical antibiotic acne treatment [11]. Niacinamide may be a better alternative to clindamycin, as bacteria involved in acne are becoming increasingly resistant to antibiotics.
Niacinamide also has anti-oxidant effects by scavenging free radicals [10]. In an in vitro study, niacinamide helped repair DNA damage due to UV exposure [13]. Overall, niacinamide increases the skin’s capacity to protect itself from damaging agents.
 
Assay: 99%
CAS#: 98-92-0 
INCI: Niacinamide
Appearance: white powder
Solubility: water
Suggested percentage: 5%

Storage: Cool, dry place. Do not freeze. Keep away from light and moisture!
Country of origin: China
[1]  D.L. Bissett, “Common cosmeceuticals,” Clinics in Dermatology, vol. 27, pp. 435–445, 2009.
[2]  D.L. Bissett, “Topical Niacinamide and Barrier Enhancement,” Proctor and Gamble Company, Cincinnati, Ohio. pp. 8-12.
[3]  D.L. Bissett, L.R. Robinson, P.S. Raleigh, K. Miyamoto, T. Hakozaki, J. Li, and G.R. Kelm, “Reduction  in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine,” Journal of Cosmetic Dermatology, vol. 6, pp. 20–26, 2007.
[4]  D. Draelos, K. Ertel, and C. Berge, “Niacinamide-Containing Facial Moisturizer Improves Skin Barrier and Benefits Subjects With Rosacea,” Therapeutics for the Clinician, vol. 76, pp. 135-141, August   2005.
[5]  W. Gehring, “Nicotinic acid/niacinamide and the skin,” Journal of Cosmetic Dermatology, vol. 3, pp.88–93, 2004.
[6]  F. Iraji and L. Banan, “The efficacy of nicotinamide gel 4% as an adjuvant therapy in the treatment of  cutaneous erosions of pemphigus vulgaris,” Dermatologic Therapy, vol. 23, pp. 308–311, 2010.
[7]  B. Kimball, J.R. Kaczvinsky, J. Li, L.R. Robinson, P.J. Matts, C.A. Berge, K. Miyamoto, and D.L. Bissett, “Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double- blind, vehicle-controlled trial,” British Journal of Dermatology, vol. 162, pp 435–441, 2010.
[8]  J. Navarrete-Solis, J.P. Castanedo-Cazares, B. Torres-Alvarez, C. Oros-Ovalle, C. Fuentes-Ahumada, F.J. Gonzalez, J.D. Martınez-Ramırez, and B. Moncada, “A Double-Blind, Randomized Clinical Trial of   Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma,” Dermatology Research and Practice, 1-5, 2011.
[9]  R. Osborne, L. A. Mullins, and L. R. Robinson, “Topical N-Acetyl Glucosamine and Niacinamide Increase Hyaluronan,” The Procter & Gamble Company, Cincinnati, Ohio USA.
[10]  N. Otte, C. Borelli, and H.C. Korting, “Nicotinamide – biologic actions of an emerging cosmetic ingredient,” International Journal of Cosmetic Science, vol. 27, pp. 255–261, 2005.
[11]  A.R. Shalita, J.G. Smith, L.C. PARISH, M.S. Sofman, and D.K. Chalker, “Topical Nicotinamide Compared with Clindamycin Gel in the Treatment of Inflammatory Acne Vulgaris,” International Journal of Dermatology, vol. 34, no. 6, pp. 434-437, June 1995.
[12]  Y. Soma, M. Kashima, A. Imaizumi, H. Takahama, T. Kawakami, and M. Mizoguchi, “Moisturizing effects of topical nicotinamide on atopic dry skin,” International Journal of Dermatology, vol. 44, pp. 197–202, 2005.
[13]  B.C. Thompson, D. Surjana, G.M. Halliday, and D.L. Damian, “Nicotinamide enhances repair of ultraviolet radiation-induced DNA damage in primary melanocytes,” Experimental Dermatology,     vol. 23, pp. 509–528, 2014.
 

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