Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
This is a fantastic product. Highly moisturizing and smooths out lines and wrinkles. It works quickly and is evening out skin tone as well. I think its a must have product and I certainly will be purchasing it again.. ...»
I am 69 and I have used this product for two years almost every day at a high dose, adding it to my antioxidant day cream, with excellent results. For me it has a very high quality and effectiveness: reduction of wrinkles, hydrated skin, unified color without blemishes ... A product of 10, the same score that I give to John for the quality of the products he sells, his excellent description / use and the bibliographic contribution.En .. ...»
María Jesus
Really loving this product. I make the best Centella toner and most concentrated ever. 2 g of centella extract dissolved in 10g of alcohol(you have to stir a lot) plus 88 grams of water and you get a very concentrated toner. Creams, toners, ampoules... all have only 0,1% of triterpenes, this toner i make have 1,4%. I am loving it, will see the results. .. ...»
excellence product, very good and made my skin soft and smooth just like baby's skin. Thank you john.. ...»
The Pre-dissolved solution is excellent. Ferulic Acid is an amazing skincare ingredient (potent antioxidant, protects other sensitive antioxidants from light degradation, UV protection) but is absolutely ineffective if it isn't solubilized correctly. Makes adding to any Serum Base or w/o emulsion easy. Love using it (at 6%; so active 0.5%) with the Resveratrol Fluid (10%; active 1%) and Green Tea Extr for potent nighttime brightening treatment... ...»
I wished i could order this in a smaller amount of 50 gr. Can i get informed when it is available ? -------------------- A. It will not be sold in smaller amounts. The review rating is meant to be for the product, not the size in which it is sold :-(.. ...»
Excellent quality, very fine texture and disperses easily when used correctly. Arrived in just seven days to London, England and with a reasonable postage fee. Very pleased... ...»
D N Bay
The best, most potent and most stable form of Vitamin C. Makes quite a difference to the appearance of mature, photo-damaged skin - don't expect results over night but with consistent use your skin will look more even and radiant!.. ...»
I bought this product before and I am here to buy it again! A high quality product for really good price... .. Thanks!.. ...»
Love the fine powder ascorbic acid. I use it in a recipe for skin care along with hyaluronic acid. I'm 65 years old and absolutely no one believes it 'cause I've been doing this for years... ...»
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Buy Gamma oryzanol For Skin Care

Gamma-oryzanol is an ingredient produced from rice bran. It contains several related molecules, build on a ferulic acid backbone, all of which share antioxidant properties. They are particularly useful in protecting lipids, such as oils, which makes oryzanol an attractive ingredient in oil-containing preparations. Furthermore, it helps reduce skin darkening from UV exposure, as well as ageing-related skin symptoms, such as roughness and wrinkling. Since gamma-oryzanol activates sebum glands, it can be used for alleviating various conditions causing dry skin. In respect to collagen degradation, oryzanol can slow down this process even more efficiently than vitamin C, thus resulting in thicker and smoother skin. At the moment, even more possible applications of oryzanol are being investigated, such as treating hair loss or preventing damage from chemotherapy. As gamma oryzanol is oil soluble, it is an ideal active to use instead of pure ferulic acid (which is alcohol soluble).

Key benefits of Gamma oryzanol in skin care:

  • Sun damage protection [4] [9] [11]
  • Antioxidant [2] [3] [5]
  • Increase skin elasticity [9]
  • Oil/sebum control [6]
  • Moisturizing and hydration [5] [6] [9]
  • Stimulate collagen production [9]
  • Lightening & brightening [9] [11]
  • Anti-androgenetic alopecia [12]
Gamma oryzanol skin care active ingredients
Product Code: BulkActives
Assay: 99.89%
CAS#: 11042-64-1
Net weight: 30g /1.06oz
Availability: Product Out Of Stock
Price: $11.30

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Gamma oryzanol

About Gamma Oryzanol  in DIY Skin Care

Gamma oryzanol skin careGamma-oryzanol is a major component in rice bran, previously believed to be a single molecule, but now considered a mixture of rather similar sterols. This collection of molecules is build on a ferulic acid backbone, with 4-desmethylsterol groups esterified to the ferulic acid. The compounds commonly referred to as Gamma-Oryzanol include: Cycloartenol and Cycloartenyl Ferulate, the latter of which is seen as the primary ingredient, Beta-sitosterol (common in many plants), 24-methylenecycloartanol, and Campesterol.

The bran gives rice a brown color and is removed when producing white rice. Around 4 % of it is the unsaponifiable fraction (molecules which are water-insoluble and cannot be turned into soaps, i.e. not fats). Oryzanol occurs in high levels in this fraction, exceeding vitamin E ten times, for example [1]–[3].

Major pharmaceutical benefit of gamma-oryzanol is the ability to act as an antioxidant. Chemical (such as smoking) and physical (such as UV exposure) factors can cause the production of free radicals inside the cell. These molecules are implicated among the main causes of ageing, cancer and other diseases [2]. They damage a wide variety of cell components, among them lipids. These lipids can only be reached by fat-soluble antioxidants, such as gamma-oryzanol, which successfully reduces lipid damage from organic radicals [3]. Various ingredients in cosmetics also suffer from oxidation. It was shown that addition of oryzanol up to concentrations of 0.5-1.0 % to several types of oils reduces their degradation, and thus this ingredient could prolong the shelf-life and effectiveness of cosmetic preparations [3]. Interestingly, oryzanol has an opposite effect on cancer cells, making them more susceptible to oxidation and possibly increasing chemotherapy efficiency [2]. This is likely related to the fact that oryzanol prevents DNA damage (mutations) in healthy cells [4]. Antioxidant activity has also been reported in a cream containing rice bran extract. Furthermore, the cream had a positive effect on volunteer skin hydration [5].

Another area of gamma-oryzanol application is regulating sebum secretion. Several Japanese studies have shown the positive effect of dermal oryzanol application on sebaceous gland activity. Application of 1 % ointment reduces the symptoms of several conditions associated with skin dryness, among them xeroderma and atopic dermatitis [6]. Cycloartenyl ferulate, one of the main components of gamma-oryzanol, has an anti-inflammatory effect, which also helps to alleviate allergic reactions [7], [8].

Even more benefits are observed when the anti-ageing effects of oryzanol are investigated. After 28 days of oryzanol-containing cream usage, volunteer skin hydration increased, while melanin synthesis (darkening) and roughness decreased [9]. Compared to other gels and creams, addition of oryzanol resulted in twice stronger positive effect on skin thickness and smoothness. Anti-wrinkle effect of this ingredient has also been reported [10]. These benefits are attributed to the inhibition of collagen-degrading enzymes – in this respect, rice bran extract is even more potent than vitamin C [9]. Gamma-oryzanol also inhibits other signaling proteins, explaining the reduced melanin synthesis [11]. Finally, recent studies have shown that oryzanol can be used as a hair loss treatment, as it promotes hair follicle proliferation and secretion of growth factors [12].
Assay: 99.89%
CAS#: 11042-64-1
Source: Rice bran
Appearance: white powder
Solubility: oil, insoluble in water
Suggested percentage: No data available - up to customer's discretion.

Storage: Store in cool and dry place. Keep away from direct strong light and heat.
Country of origin: China
[1]          M. K. Sharif, M. S. Butt, F. M. Anjum, and S. H. Khan, “Rice bran: a novel functional ingredient,” Crit. Rev. Food Sci. Nutr., vol. 54, no. 6, pp. 807–816, 2014.
[2]          P. Klongpityapong, R. Supabphol, and A. Supabphol, “Antioxidant effects of gamma-oryzanol on human prostate cancer cells,” Asian Pac. J. Cancer Prev. APJCP, vol. 14, no. 9, pp. 5421–5425, 2013.
[3]          C. Juliano, M. Cossu, M. C. Alamanni, and L. Piu, “Antioxidant activity of gamma-oryzanol: mechanism of action and its effect on oxidative stability of pharmaceutical oils,” Int. J. Pharm., vol. 299, no. 1–2, pp. 146–154, Aug. 2005.
[4]          C. Punvittayagul, K. Sringarm, C. Chaiyasut, and R. Wongpoomchai, “Mutagenicity and antimutagenicity of hydrophilic and lipophilic extracts of Thai northern purple rice,” Asian Pac. J. Cancer Prev. APJCP, vol. 15, no. 21, pp. 9517–9522, 2014.
[5]          A. Manosroi, R. Chutoprapat, Y. Sato, K. Miyamoto, K. Hsueh, M. Abe, W. Manosroi, and J. Manosroi, “Antioxidant activities and skin hydration effects of rice bran bioactive compounds entrapped in niosomes,” J. Nanosci. Nanotechnol., vol. 11, no. 3, pp. 2269–2277, Mar. 2011.
[6]          Oryza Oil & Fat Chemical Co., “Gamma-oryzanol: Food and cosmetic ingredient,” 2010.
[7]          M. S. Islam, H. Yoshida, N. Matsuki, K. Ono, R. Nagasaka, H. Ushio, Y. Guo, T. Hiramatsu, T. Hosoya, T. Murata, M. Hori, and H. Ozaki, “Antioxidant, free radical-scavenging, and NF-kappaB-inhibitory activities of phytosteryl ferulates: structure-activity studies,” J. Pharmacol. Sci., vol. 111, no. 4, pp. 328–337, Dec. 2009.
[8]          T. Oka, M. Fujimoto, R. Nagasaka, H. Ushio, M. Hori, and H. Ozaki, “Cycloartenyl ferulate, a component of rice bran oil-derived gamma-oryzanol, attenuates mast cell degranulation,” Phytomedicine Int. J. Phytother. Phytopharm., vol. 17, no. 2, pp. 152–156, Feb. 2010.
[9]          A. Manosroi, R. Chutoprapat, M. Abe, W. Manosroi, and J. Manosroi, “Anti-aging efficacy of topical formulations containing niosomes entrapped with rice bran bioactive compounds,” Pharm. Biol., vol. 50, no. 2, pp. 208–224, Feb. 2012.
[10]        M. J. Lerma-García, J. M. Herrero-Martínez, E. F. Simó-Alfonso, C. R. B. Mendonça, and G. Ramis-Ramos, “Composition, industrial processing and applications of rice bran γ-oryzanol,” Food Chem., vol. 115, no. 2, pp. 389–404, Jul. 2009.
[11]        H. Jun, J. H. Lee, B.-R. Cho, W.-D. Seo, H.-W. Kang, D.-W. Kim, K.-J. Cho, and S.-J. Lee, “Dual inhibition of γ-oryzanol on cellular melanogenesis: inhibition of tyrosinase activity and reduction of melanogenic gene expression by a protein kinase A-dependent mechanism,” J. Nat. Prod., vol. 75, no. 10, pp. 1706–1711, Oct. 2012.
[12]        J.-S. Choi, M.-H. Jeon, W.-S. Moon, J.-N. Moon, E. J. Cheon, J.-W. Kim, S. K. Jung, Y.-H. Ji, S. W. Son, and M.-R. Kim, “In vivo hair growth-promoting effect of rice bran extract prepared by supercritical carbon dioxide fluid,” Biol. Pharm. Bull., vol. 37, no. 1, pp. 44–53, 2014.

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