Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
Reviews
I wished i could order this in a smaller amount of 50 gr. Can i get informed when it is available ? -------------------- A. It will not be sold in smaller amounts. The review rating is meant to be for the product, not the size in which it is sold :-(.. ...»
Diana
Excellent quality, very fine texture and disperses easily when used correctly. Arrived in just seven days to London, England and with a reasonable postage fee. Very pleased... ...»
D N Bay
The best, most potent and most stable form of Vitamin C. Makes quite a difference to the appearance of mature, photo-damaged skin - don't expect results over night but with consistent use your skin will look more even and radiant!.. ...»
Judy
I bought this product before and I am here to buy it again! A high quality product for really good price... .. Thanks!.. ...»
Raisa
Love the fine powder ascorbic acid. I use it in a recipe for skin care along with hyaluronic acid. I'm 65 years old and absolutely no one believes it 'cause I've been doing this for years... ...»
Kathy
As all products from bulkactives, this is a really great and high-quality DYI ingredient. Along with John's friendly, reliable and very efficient service, it makes a purchase from bulkactives a very pleasant experience... ...»
Sandra
Purchased this some time ago from BulkActives and here to buy some more! Great stuff!!!!.. ...»
Kathy
I mixed it with some other water actives like Glucosamine, Niacinamide, Glutathione etc into the Pre Liposome Microemulsion and the serum was very smooth and moisturizing. As it claims, it penetrates into the skin very well. I will mix it with oil soluble actives in my next batch. .. ...»
RRR
Awesome Product and thanks for such a nice Product description .. ...»
Stephen
Excellent product! Easy to use. Add to your cream or oil, mix, and that's it! After applying cream with peptides, my skin was really smooth and nourishing. Very happy that BulkActives offers such high quality product for really good price... ...»
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Buy Niacinamide (Vitamin B3) For Skin Care

Niacinamide, also known as nicotinamide, is a water soluble form of vitamin B3. Vitamin B3 is essential for maintaining skin health. Niacinamide increases production of important skin structural components such as collagen, ceramide, and keratin. This helps increase moisture and strengthen skin. Niacinamide is known to decrease hyperpigmentation, effectively lightening and brightening skin, especially when used together with n-acetyl glucosamine, a hyaluronic acid precursor. It reduces wrinkles and again, this effect is better with n-acetyl glucosamine. Niacinamide also effectively helps reduce acne and heal wounds. It has anti-oxidant and anti-inflammatory properties. Overall, niacinamide is a compound with many different uses that can increase overall skin health.

Key benefits of Niacinamide in skin care:

  • Treat hyperpigmentation [3] [7] [8]
  • Lightening and brightening [3] [7] [8]
  • Reduce fine lines and wrinkles [9]
  • Anti-inflammatory [5] [6] [8]
  • Anti-oxidant [10] [13]
  • Anti-acne [1] [5] [11]
  • Moisturizing and hydration [2] [5] [12]
  • Restore barrier function [2] [5] [12]
  • Wound healing support [5] [6]
  • Increase skin elasticity [5] [9]
  • Oil/sebum control [2]
  • Pore refinement [2]
  • Sun damage repair [13]
  • Sun damage protection [10]
  • Stimulate collagen production [5]
  • Stimulate HA production [9]
Niacinamide (Vitamin B3) skin care active ingredients
Product Code: BulkActives
Reward Points: 3
Assay: 99%
CAS#: 98-92-0
Net weight: 30g /1.06oz
Availability: In Stock
Price: $5.10
Reward Points: 255


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Niacinamide (Vitamin B3)

About Niacinamide in DIY Skin Care

Niacinamide, also known as nicotinamide, is water soluble vitamin B3 [5]. Vitamin B3 is essential for maintaining the overall health of skin. Vitamin B3 deficiency causes excessive dryness, skin lesions, and sensitivity to sunlight. Niacinamide is a precursor to coenzymes nicotinamide adenine dinucleotide [NAD] and nicotinamide adenine dinucleotide phosphate [NADP]. These are important for many reactions in the body, including those that happen in the skin. NADPH, the hydrogenated form of NADP, is reported to decrease with age [2]. Treatment with niacinamide increases NADP in aged fibroblasts [collagen producing cells] [10]. Thus, niacinamide helps maintain normal amounts of these coenzymes in the skin. Niacinamide is suitable for topical use, as it penetrates easily [5]. It is water soluble and thus, easily used in formulations, and stable. It is tolerated by skin in high concentrations [10].

Niacinamide stimulates ceramide and fatty acid production, major components of skin that provide barrier function [12]. Topical niacinamide stabilizes skin barrier function and reduces moisture loss [5]. A clinical study using topical niacinamide showed it reduces symptoms of dry skin [12]. Topical niacinamide applied to aging skin improves skin surface structure and smoothes out wrinkles [5]. It also reduces skin yellowing, red facial blotches, and pore size by reducing sebum [oil] excretion [1].

Niacinamide also helps reduce hyperpigmentation. Hyperpigmentation involves age spots that are clusters of melanin. Researchers believe niacinamide reduces hyperpigmentation by inhibiting the transfer of cell compartments called melanosomes that store melanin [7]. In clinical studies, topical 4% niacinamide inhibits pigmentation [7, 8]. A greater effect was seen when combined with 2% n-acetyl glucosamine, a hyaluronic acid precursor [3, 7]. Both have different mechanisms of reducing pigmentation, so, used together, they produce a better result.

Niacinamide has great potential as an anti-aging treatment. It has shown to increase keratin synthesis [5]. Keratin is an important structural protein in the skin and levels decrease with age. This reduces the structural soundness of skin and water binding capabilities. Overall, niacinamide stimulates cell growth, including collagen [5]. Collagen is another important structural component of the skin that helps maintain elasticity and plays a role in wound healing. Niacinamide is also a cofactor in hyaluronic acid synthesis [9]. Hyaluronic acid is important for retaining moisture in the skin and protecting barrier function. Levels are known to decrease with age, contributing to wrinkle formation. Thus, increasing hyaluronic acid improves skin elasticity and smoothness. An in vitro study shows 4% niacinamide increases hyaluronic acid. Women using a 2% NAG and 4% niacinamide combined showed improved fine lines and wrinkles, especially under the eyes [9]. This shows the anti-aging effects of niacinamide are best when combined with n-acetyl glucosamine.

It also has anti-inflammatory effects [5]. A clinical study using niacinamide showed reduced rosacea symptoms [4]. It also improved facial skin barrier. In a clinical study, niacinamide also reduced immune cell infiltration that promotes inflammation [8]. Topical 4% niacinamide increased cell growth and helped heal skin lesions [6]. It also reduced acne similar to 1% clindamycin, a common topical antibiotic acne treatment [11]. Niacinamide may be a better alternative to clindamycin, as bacteria involved in acne are becoming increasingly resistant to antibiotics.
Niacinamide also has anti-oxidant effects by scavenging free radicals [10]. In an in vitro study, niacinamide helped repair DNA damage due to UV exposure [13]. Overall, niacinamide increases the skin’s capacity to protect itself from damaging agents.
 
Assay: 99%
CAS#: 98-92-0 
INCI: Niacinamide
Appearance: white powder
Solubility: water
Suggested percentage: 5%

Storage: Cool, dry place. Do not freeze. Keep away from light and moisture!
Country of origin: China
[1]  D.L. Bissett, “Common cosmeceuticals,” Clinics in Dermatology, vol. 27, pp. 435–445, 2009.
[2]  D.L. Bissett, “Topical Niacinamide and Barrier Enhancement,” Proctor and Gamble Company, Cincinnati, Ohio. pp. 8-12.
[3]  D.L. Bissett, L.R. Robinson, P.S. Raleigh, K. Miyamoto, T. Hakozaki, J. Li, and G.R. Kelm, “Reduction  in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine,” Journal of Cosmetic Dermatology, vol. 6, pp. 20–26, 2007.
[4]  D. Draelos, K. Ertel, and C. Berge, “Niacinamide-Containing Facial Moisturizer Improves Skin Barrier and Benefits Subjects With Rosacea,” Therapeutics for the Clinician, vol. 76, pp. 135-141, August   2005.
[5]  W. Gehring, “Nicotinic acid/niacinamide and the skin,” Journal of Cosmetic Dermatology, vol. 3, pp.88–93, 2004.
[6]  F. Iraji and L. Banan, “The efficacy of nicotinamide gel 4% as an adjuvant therapy in the treatment of  cutaneous erosions of pemphigus vulgaris,” Dermatologic Therapy, vol. 23, pp. 308–311, 2010.
[7]  B. Kimball, J.R. Kaczvinsky, J. Li, L.R. Robinson, P.J. Matts, C.A. Berge, K. Miyamoto, and D.L. Bissett, “Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double- blind, vehicle-controlled trial,” British Journal of Dermatology, vol. 162, pp 435–441, 2010.
[8]  J. Navarrete-Solis, J.P. Castanedo-Cazares, B. Torres-Alvarez, C. Oros-Ovalle, C. Fuentes-Ahumada, F.J. Gonzalez, J.D. Martınez-Ramırez, and B. Moncada, “A Double-Blind, Randomized Clinical Trial of   Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma,” Dermatology Research and Practice, 1-5, 2011.
[9]  R. Osborne, L. A. Mullins, and L. R. Robinson, “Topical N-Acetyl Glucosamine and Niacinamide Increase Hyaluronan,” The Procter & Gamble Company, Cincinnati, Ohio USA.
[10]  N. Otte, C. Borelli, and H.C. Korting, “Nicotinamide – biologic actions of an emerging cosmetic ingredient,” International Journal of Cosmetic Science, vol. 27, pp. 255–261, 2005.
[11]  A.R. Shalita, J.G. Smith, L.C. PARISH, M.S. Sofman, and D.K. Chalker, “Topical Nicotinamide Compared with Clindamycin Gel in the Treatment of Inflammatory Acne Vulgaris,” International Journal of Dermatology, vol. 34, no. 6, pp. 434-437, June 1995.
[12]  Y. Soma, M. Kashima, A. Imaizumi, H. Takahama, T. Kawakami, and M. Mizoguchi, “Moisturizing effects of topical nicotinamide on atopic dry skin,” International Journal of Dermatology, vol. 44, pp. 197–202, 2005.
[13]  B.C. Thompson, D. Surjana, G.M. Halliday, and D.L. Damian, “Nicotinamide enhances repair of ultraviolet radiation-induced DNA damage in primary melanocytes,” Experimental Dermatology,     vol. 23, pp. 509–528, 2014.
 

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