Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
Reviews
I wished i could order this in a smaller amount of 50 gr. Can i get informed when it is available ? -------------------- A. It will not be sold in smaller amounts. The review rating is meant to be for the product, not the size in which it is sold :-(.. ...»
Diana
Excellent quality, very fine texture and disperses easily when used correctly. Arrived in just seven days to London, England and with a reasonable postage fee. Very pleased... ...»
D N Bay
The best, most potent and most stable form of Vitamin C. Makes quite a difference to the appearance of mature, photo-damaged skin - don't expect results over night but with consistent use your skin will look more even and radiant!.. ...»
Judy
I bought this product before and I am here to buy it again! A high quality product for really good price... .. Thanks!.. ...»
Raisa
Love the fine powder ascorbic acid. I use it in a recipe for skin care along with hyaluronic acid. I'm 65 years old and absolutely no one believes it 'cause I've been doing this for years... ...»
Kathy
As all products from bulkactives, this is a really great and high-quality DYI ingredient. Along with John's friendly, reliable and very efficient service, it makes a purchase from bulkactives a very pleasant experience... ...»
Sandra
Purchased this some time ago from BulkActives and here to buy some more! Great stuff!!!!.. ...»
Kathy
I mixed it with some other water actives like Glucosamine, Niacinamide, Glutathione etc into the Pre Liposome Microemulsion and the serum was very smooth and moisturizing. As it claims, it penetrates into the skin very well. I will mix it with oil soluble actives in my next batch. .. ...»
RRR
Awesome Product and thanks for such a nice Product description .. ...»
Stephen
Excellent product! Easy to use. Add to your cream or oil, mix, and that's it! After applying cream with peptides, my skin was really smooth and nourishing. Very happy that BulkActives offers such high quality product for really good price... ...»
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Phytosterol

Phytosterols are a family of plant-produced molecules with diverse health benefits. In cosmetics, the ability to stimulate collagen production is most interesting. Together with antioxidant activity and down-regulation of collagen degrading enzymes, these abilities help repair damage in photoaged skin. Phytosterols also have anti-inflammatory properties, which are useful in UV protection, dermatitis treatment, and even cancer prevention. They are widely used in burn wound care – phytosterols were found to improve healing, improve scar appearance and possess analgesic properties, reducing the need of opiate drugs. Antimicrobial activity of phytosterols is also important in skin care, as it can be utilized in both wound care and general fight against infections, such as Candida. Finally, phytosterols regulate transport of cholesterol and thus sebum production – this may present a good treatment option for acne and other sebum-related conditions.

NOTE: To assist you with solubility issues, we now also sell Phytosterol in a standardized  pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 11% solution gives 1% Phytosterols content in final product.
    32% solution gives 3% Phytosterols content in final product.
    53% solution gives 5% Phytosterols content in final product.

Key benefits of Phytosterols in skin care:

  • Anti-inflammatory [2], [12]–[14]
  • Anti-bacterial [6], [7]
  • Oil/sebum control [8]
  • Anti-acne [8]
  • Sun damage protection [10], [11]
  • Stimulate collagen production [9]–[11]
  • Restore barrier function [5]
  • Matrix metalloproteinase (MMP) inhibitors [9]–[11]
  • Wound healing support [3]–[5]
  • Scar care [3]–[5]
Product Code: BulkActives
Reward Points: 4
Assay: 95%
CAS#: 68555-08-8
Net weight: 30g /1.06oz & 50g / 1.76oz
Availability:
Standardized preDissolved solution 100g - Options In Stock
Standardized pre-dissolved solution 50g - Options In Stock
Standardized Powder 30g - Options In Stock
Price: $6.80
Reward Points: 420


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About Phytosterol in Skin Care

Phytosterols or plant sterols is a common name for several plant-produced molecules. These molecules cannot be produced in human body, and usually are obtained from oil, nuts and general vegetarian diet. The most abundant plant sterols are campesterol, stigmasterol and beta-sitosterol, with the latter being most important biologically [1]. Other sterols, however, are also continuously investigated, and new applications are being discovered every year.

Beta-sitosterol is most known for its use in wound care. Its anti-inflammatory activity was described long ago, and it is also an antipyretic (reduces fever) of similar strength to aspirine [2]. These properties led to the development of a burn ointment using beta-sitosterol as main active ingredient. It is used to accelerate healing, reduce scarring, and prevent bacterial growth [3], [4]. Clinical studies found that this treatment also helps restore the barrier function of the skin, measured by reduced water loss. Interestingly, this effect was found to be associated with better scar appearance, demonstrating a relation between clinical and cosmetical functions [5]. Improved scar appearance can be already observed after 1 month of treatment, which is relatively fast for scar-treating cosmeceuticals [4]. Furthermore, this ointment has an analgesic effect, with patients requiring much less opiate painkillers while using this mixture [3].

The antibacterial effect of plant sterols is useful in both wound care and general hygiene. While investigating an extract from Alpinia conchigera, researchers found that the main components were phytosterols – stigmasterol and beta-sitosterol [6]. This extract had a strong effect against various pathogenic microbes, including fungi, such as Candida albicans, and even generally resistant bacteria, such as Staphylococcus aureus MRSA strains. Other plant sterol extracts, such as one produced from Aloe vera, also are effective against Candida and other pathogens [7].
Phytosterols also have health benefits in other areas. They reduce the levels of LDL cholesterol, commonly known as “bad cholesterol” [1]. This is relevant not only to the cardiovascular system, as cholesterol accumulation in the skin causes seborrhea, acne, rosacea and other skin diseases. Dermal application of plant sterols can be used to reduce cholesterol transport into skin cells, and thus prevent the cholesterol-related disorders [8].

In the recent years, new collagen-restoring effects of phytosterols have been discovered. Skin cells, treated with phytosterols found in yam plant (diosgenin, stigmasterol and beta-sitosterol), had reduced levels of collagen-degrading enzymes, resulting in significantly enhanced collagen secretion [9]. Spinasterol, another phytosterol, can both increase the synthesis of collagen and decrease the synthesis of degrading enzymes [10]. Fucosterol also has these effects, and additionally promotes antioxidant enzyme synthesis. These benefits were confirmed using skin cells treated with UV (photoaged skin), proving that phytosterols are beneficial for solar protection as well [10], [11]. Dermal applications of spinasterol also reduce edema, indicating anti-inflammatory properties [12]. Furthermore, atopic dermatitis, an inflammatory disease, can be treated with applications of beta-sitosterol [13]. In fact, by reducing inflammation, beta-sitosterol and other phytosterols even reduce the likelihood of cancer development [14].
 
NOTE: To assist you with solubility issues, we now also sell Phytosterol in a standardized  pre-dissolved solution. Just add the liquid to your cream and mix well.

Phytosterol Standardized Powder

Assay: 95%
CAS No. 68555-08-8
INCI: Phytosterols
Appearance: powder
Solubility: Ethyl Hexyl Palmitate
Suggested percentage:  1 to 10%

Storage: Cool, dry place. Do not freeze. Keep away from light and moisture!
Country of origin: China

Phytosterol Standardized Pre Dissolved Solution - 10%

Assay: 9.5%
CAS#:29806-73-3, 68555-08-8
INCI: Ethyl Hexyl Palmitate, Phytosterols
Appearance: liquid

Solubility: add to cream
Suggested percentage:
11% solution gives 1% Phytosterols content in final product.
32% solution gives 3% Phytosterols content in final product.
53% solution gives 5% Phytosterols content in final product.

Storage: Store in fridge, do not freeze.
Country of origin for raw material: China
Country of manufacture: Taiwan
[1]          B. J. Grattan, “Plant Sterols as Anticancer Nutrients: Evidence for Their Role in Breast Cancer,” Nutrients, vol. 5, no. 2, pp. 359–387, Jan. 2013.
[2]          M. B. Gupta, R. Nath, N. Srivastava, K. Shanker, K. Kishor, and K. P. Bhargava, “Anti-inflammatory and antipyretic activities of beta-sitosterol,” Planta Med., vol. 39, no. 2, pp. 157–163, Jun. 1980.
[3]          E. S. Ang, S. T. Lee, C. S. Gan, P. G. See, Y. H. Chan, L. H. Ng, and D. Machin, “Evaluating the role of alternative therapy in burn wound management: randomized trial comparing moist exposed burn ointment with conventional methods in the management of patients with second-degree burns,” MedGenMed Medscape Gen. Med., vol. 3, no. 2, p. 3, Mar. 2001.
[4]          B. S. Atiyeh, J. Ioannovich, C. A. Al-Amm, K. A. El-Musa, and R. Dham, “Improving scar quality: a prospective clinical study,” Aesthetic Plast. Surg., vol. 26, no. 6, pp. 470–476, Dec. 2002.
[5]          B. S. Atiyeh, K. A. El-Musa, and R. Dham, “Scar quality and physiologic barrier function restoration after moist and moist-exposed dressings of partial-thickness wounds,” Dermatol. Surg. Off. Publ. Am. Soc. Dermatol. Surg. Al, vol. 29, no. 1, pp. 14–20, Jan. 2003.
[6]          A. N. Aziz, H. Ibrahim, D. Rosmy Syamsir, M. Mohtar, J. Vejayan, and K. Awang, “Antimicrobial compounds from Alpinia conchigera,” J. Ethnopharmacol., vol. 145, no. 3, pp. 798–802, Feb. 2013.
[7]          R. Bawankar, V. C. Deepti, P. Singh, R. Subashkumar, G. Vivekanandhan, and S. Babu, “Evaluation of bioactive potential of an Aloe vera sterol extract,” Phytother. Res. PTR, vol. 27, no. 6, pp. 864–868, Jun. 2013.
[8]          S. Rozner, L. Verkhovski, Y. Nissimov, A. Aserin, R. Vilensky, D. Danino, C. C. Zouboulis, Y. Milner, and N. Garti, “Inhibition of cholesterol transport into skin cells in cultures by phytosterol-loaded microemulsion,” Chem. Phys. Lipids, vol. 153, no. 2, pp. 109–118, Jun. 2008.
[9]          L.-H. Chiang, S.-H. Chen, and A.-I. Yeh, “Preparation of nano/submicrometer yam and its benefits on collagen secretion from skin fibroblast cells,” J. Agric. Food Chem., vol. 60, no. 50, pp. 12332–12340, Dec. 2012.
[10]        T. H. Lee, S. M. Lee, D.-Y. Lee, Y. Son, D. K. Chung, N.-I. Baek, and J. Kim, “A glycosidic spinasterol from Koreana stewartia promotes procollagen production and inhibits matrix metalloproteinase-1 expression in UVB-irradiated human dermal fibroblasts,” Biol. Pharm. Bull., vol. 34, no. 5, pp. 768–773, 2011.
[11]        M.-S. Kim, G.-H. Oh, M.-J. Kim, and J.-K. Hwang, “Fucosterol inhibits matrix metalloproteinase expression and promotes type-1 procollagen production in UVB-induced HaCaT cells,” Photochem. Photobiol., vol. 89, no. 4, pp. 911–918, Aug. 2013.
[12]        S. Boller, C. Soldi, M. C. A. Marques, E. P. Santos, D. A. Cabrini, M. G. Pizzolatti, A. R. Zampronio, and M. F. Otuki, “Anti-inflammatory effect of crude extract and isolated compounds from Baccharis illinita DC in acute skin inflammation,” J. Ethnopharmacol., vol. 130, no. 2, pp. 262–266, Jul. 2010.
[13]        N.-R. Han, H.-M. Kim, and H.-J. Jeong, “The β-sitosterol attenuates atopic dermatitis-like skin lesions through down-regulation of TSLP,” Exp. Biol. Med. Maywood NJ, vol. 239, no. 4, pp. 454–464, Apr. 2014.
[14]        K. Yasukawa, M. Takido, T. Matsumoto, M. Takeuchi, and S. Nakagawa, “Sterol and triterpene derivatives from plants inhibit the effects of a tumor promoter, and sitosterol and betulinic acid inhibit tumor formation in mouse skin two-stage carcinogenesis,” Oncology, vol. 48, no. 1, pp. 72–76, 1991.
 
 

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