Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
Tried this on my week-old rash from flea bites. Got an almost instant relief and rash healed in 2 days. Tried it on my daughter who has eczema for a very long time. The rashes calmed down after a few days and her skin is now healing well. Really great product. Just put in order for another jar.... ...»
Really loving this product. I make the best Centella toner and most concentrated ever. 2 g of centella extract dissolved in 10g of alcohol(you have to stir a lot) plus 88 grams of water and you get a very concentrated toner. Creams, toners, ampoules... all have only 0,1% of triterpenes, this toner i make have 1,4%. I am loving it, will see the results. .. ...»
Just recently ordered this and LOVE! Green Tea EGCG truly is one of the most fantastic skincare actives out there. Very difficult to find good quality product (90%) and even harder to actually solubilize it! Love that it comes in pre-dissolved solution. I enjoy adding it at 1% (so 11% sol) to my serum formulations containing Niacinamide 5% + NAG 3%. Excellent for oily acne prone skin. *Only gripe... because the Pre-Dissolved Solution is SO heavy in propanediol (10 parts Propanediol for 1 part E.. ...»
Wonderful base cream! Only multi-lamellar structured cream I've found on the market. Cream itself is lightweight (no oil) yet very conditioning/hydrating. Easily accepts water-soluble active ingredients as well as oil-soluble ones. I've even pushed the additional ingred % up to 20 (meaning 80% this cream, 20% added) without any separation issues. Ideal base cream for delivering actives. Personal favorite recipe calls for 5% straight Grapeseed Oil with 5% SebumREG oil active + Panthenol 1% + E Ac.. ...»
Excellent quality, very fine texture and disperses easily when used correctly. Arrived in just seven days to London, England and with a reasonable postage fee. Very pleased... ...»
D N Bay
This ingredient has done more for my skin than anything else I've ever used. I put it into a spray facial toner and use it morning and night. I noticed the effects immediately, they were that dramatic. I will use this forever, no question... ...»
This product is amazing! I'm new to diy moisturizing cream and I've done quite a bit of research. However, I found info. at BulkActives that I have not seen anywhere else, especially with the hyaluronic acid. This product is of high quality, my friend is a chemist and he ran some tests, very high quality. It has done wonders for my skin, not only in the way it looks more healthy but it just feels so smooth and hydrated. I'm still experimenting with some recipes so I will return. Your service is .. ...»
Karen S.
I've been using Bulkactives green tea EGCG for four years. No complaints, it blends nicely my DIY anti-aging cream. I can feel a bit of toning and definitely notice the anti-inflammatory effects on my skin. Two observations that keep the rating 4 stars instead of 5: (1) A package of green tea contains significantly less weight/volume than the package of grape seed extract that I order from bulkactives. The two are combined in equal amounts in the anti-aging cream, so I find myself running o.. ...»
Theresa Andrews
Awesome Product and thanks for such a nice Product description .. ...»
I have been buying from bulkactives for some time and have never been disappointed. My most recent purchases have been the hyaluronic acid and the dispenser bottle. the bottle is great. The inner container rises with use, ensuring that you use most of the product. Much better than having residue sit at bottom of bottle to be wasted. I've used only one batch of hyaloronic acid formula, so too early to report. I mix it with ascorbic L and ferulic acid, according to recipe on this site. So f.. ...»
Suzanne Ryan
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Alpha Bisabolol (sustainable)

EcoFriendly, sustainable, synthetic Alpha Bisabolol , which offers all the benefits of natural Alpha Bisabolol, is now available.
For thousands of years, chamomile has been a prized component of many ancient therapies.  The active ingredient of chamomile, α-bisabolol, is a lightly floral-scented essential oil extracted from the Candeia tree, a tropical relative of cammomile, in modern times. In order to produce 100 tons of α-bisabolol, 850 hectares of timber must be harvested . Due to deforestation amid a global high demand, synthetic sources of α-bisabolol are now available.  New generations of the synthetic compound offer 85% α-bisabolol content and all of the benefits of the natural product.  Easily absorbed by the skin, α-bisabolol is a potent anti-microbial agent, anti-inflammatory, and potent wound-care agent.   It has valuable applications in soaps, lotions, soothing face creams, and wound-healing products

Key benefits of Sustainable Alpha Bisabolol in skin care:

  • Anti-bacterial [1] [2] [3] [6]
  • Anti-acne [1] [2] [3] [6] [7]
  • Anti-inflammatory [1] [2] [3] [7]
  • Moisturizing and hydration [9]
  • Sun damage repair [1] [7]
  • Wound healing support [2] [9]
  • Reduce rosacea
Product Code: BulkActives
Reward Points: 10
Assay: 95% min
CAS#: 515-69-5
Net weight: 50g / 1.76oz & 1kg / 35.27oz
50g / 1.76oz - Options In Stock
1kg / 35.27oz - Options In Stock
Price: $21.30
Reward Points: 995

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About Sustainable Alpha Bisabolol in DIY Skin Care

Oil extracts of the chamomile plant have been used medicinally for millennia.  From China to Egypt to Greece to Brazil, chamomile has been used historically to soothe upset stomachs, reduce inflammation, and ease menstrual pain.  One constituent of this plant in particular, α-bisabolol, has been shown to have powerful antibacterial, antifungi, anti-inflammatory, and tissue regeneration/wound-healing properties [1-3].  This sesquiterpene alcohol is monocyclic and fragrant, and has been included in formulations for lotions, aftershaves, after-sun care products, and various other cosmetics including face creams and lipsticks [2]. 

The plant from which α-bisabolol is extracted is a tropical cousin of chamomile called Candeia, a tree harvested primarily in Brazil.  In order to produce 100 tons of α-bisabolol, 850 hectares of timber must be harvested [4].  Due to the rising demand for α-bisabolol for use in high-end skin care products, it is of little surprise then that the Candeia trees are over-harvested.  In order to meet the demand for this essential oil, scientists have found a way to synthesize α-bisabolol that does not have any significant environmental impact.  Huge strides have been made recently in improving the purity and yield of synthetic α-bisabolol with the newest generation of product available having 85% α-bisabolol content.  Although this value still falls slightly below the 95% α-bisabolol content obtained when sourced naturally, synthetic α-bisabolol offers all of the same benefits without contributing to deforestation and emission of greenhouse gases [5].

α-bisabolol is a powerful anti-microbial agent with known bactericidal properties against Mycobacterium tuberculosis, Salmonella typhimurium, and Staphylococcus aureus [6].  Further, fungistatic effects against Candida albicans and Trichophyton mentagrophytes have been reported [6].  As such, α-bisabolol is a desirable component for soaps.

 A recent in vivo mouse study demonstrated that α-bisabolol is effective in reducing inflammation-induced edema of the paw and, via a separate mechanism, also demonstrated anti-nociceptive activity [3].  The anti-inflammatory properties of α-bisabolol have been attributed to reduced release of inflammation-inducing mediators prostaglandin E2 and Cox-2 [7]. 

A rat model investigating the effects of α-bisabolol on wound healing demonstrated that topical application of the compound increases the rate of tissue regeneration [8].  Furthermore, α-bisabolol increases the tensile strength of new tissues [9].  Together, this marks α-bisabolol as an attractive agent for use in sun-damage repair creams as well as wound-care ointments.  There is also speculation that the tissue regeneration promoting abilities of α-bisabolol can reduce the appearance of wrinkles and make skin appear younger; however, this has yet to be validated.

In addition to the ability of α-bisabolol to directly benefit the skin, it has the capability to enhance absorption of other active ingredients by the skin.  Studies have shown that incorporation of α-bisabolol and additional active ingredients into skin care products has increased the absorption of other ingredients by many-fold [9].  Therefore, incorporation of multiple actives can only be enhanced by utilization of α-bisabolol.

Assay: 85%
CAS#: 515-69-5
INCI: Bisabolol
Appearance: Clear, colorless to slightly yellowish liquid with a mild floral, slightly sweet aroma
Solubility:  Soluble in ethanol, natural, mineral and synthetic oils, insoluble in water
Suggested percentage: 0.5 - 1%
Usage: add to the oil or alcohol phase of your formulation, or add directly to a pre-made cream/lotion.

Shelf Life:  2 years from date of purchase
Storage:  Store in a very cool (not refrigerated) and dry place away from direct sunlight and heat.
Manufacturer: BASF

[1]  Villegas LF, Marçalo A, Martin J, Fernández ID, Maldonado H, Vaisberg AJ, et al. [+]-epi-α-Bisbolol Is the Wound-Healing Principle of Peperomia galioides: Investigation of the in Vivo Wound-Healing Activity of Related Terpenoids. Journal of Natural Products. 2001;64[10]:1357-9.
[2]  MacLeish NF. Revision of Eremanthus [Compositae: Vernonieae]. Annals of the Missouri Botanical Garden. 1987:265-90.
[3]  Rocha N, Rios E, Carvalho A, Cerqueira G, Lopes AA, Leal L, et al. Anti-nociceptive and anti-inflammatory activities of [−]-α-bisabolol in rodents. Naunyn-Schmiedeberg's Arch Pharmacol. 2011;384[6]:525-33.
[4]  CLARK A. Promoting Sustainability in the Value Chain of Natural Bisabolol, a Brazilian Rainforest Product. New York: Columbia University. 2011.
[5]  Paula A, Rodrigues P. Promoting Sustainability in the Value Chain of Natural. 2011.
[6]  Singh O, Khanam Z, Misra N, Srivastava MK. Chamomile [Matricaria chamomilla L.]: an overview. Pharmacognosy reviews. 2011;5[9]:82.
[7]  Srivastava JK, Pandey M, Gupta S. Chamomile, a novel and selective COX-2 inhibitor with anti-inflammatory activity. Life Sciences. 2009;85[19–20]:663-9.
[8]  Rezaie A, Mohajeri D, Zarkhah A, Nazeri M. Comparative assessment of Matricaria chamomilla and zinc oxide on healing of experimental skin wounds on rats. Annals of Biological Research. 2012;3[1].
[9]  Fatima Ad, Modolo LV, Conegero Sanches AC, Porto RR. Wound healing agents: the role of natural and non-natural products in drug development. Mini reviews in medicinal chemistry. 2008;8[9]:879-88.

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