Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
Reviews
The Pre-dissolved solution is excellent. Ferulic Acid is an amazing skincare ingredient (potent antioxidant, protects other sensitive antioxidants from light degradation, UV protection) but is absolutely ineffective if it isn't solubilized correctly. Makes adding to any Serum Base or w/o emulsion easy. Love using it (at 6%; so active 0.5%) with the Resveratrol Fluid (10%; active 1%) and Green Tea Extr for potent nighttime brightening treatment... ...»
James
I am very happy with both the quality and packaging of the Ferulic acid I ordered. It came in foil packets (I ordered two). Will buy from them again as I use the product in my Vitamin C serum to maintain the PH needed... ...»
DBallings
Just recently ordered this and LOVE! Green Tea EGCG truly is one of the most fantastic skincare actives out there. Very difficult to find good quality product (90%) and even harder to actually solubilize it! Love that it comes in pre-dissolved solution. I enjoy adding it at 1% (so 11% sol) to my serum formulations containing Niacinamide 5% + NAG 3%. Excellent for oily acne prone skin. *Only gripe... because the Pre-Dissolved Solution is SO heavy in propanediol (10 parts Propanediol for 1 part E.. ...»
Victor
Wonderful base cream! Only multi-lamellar structured cream I've found on the market. Cream itself is lightweight (no oil) yet very conditioning/hydrating. Easily accepts water-soluble active ingredients as well as oil-soluble ones. I've even pushed the additional ingred % up to 20 (meaning 80% this cream, 20% added) without any separation issues. Ideal base cream for delivering actives. Personal favorite recipe calls for 5% straight Grapeseed Oil with 5% SebumREG oil active + Panthenol 1% + E Ac.. ...»
Vic
excellence product, very good and made my skin soft and smooth just like baby's skin. Thank you john.. ...»
nky
Im 45 years old; average looking skin for my age. Applied a small pea sized amount of Sea Kelp Bioferment to my face full strength in the am after washing my face of previous night makeup.; let face "dry". Then aplied my foundation as always. Noticed my thick, heavy foundation applied more easily and smooth. Keep in mind this is DAY TWO of me using this. TWO women at work ( separate departments) commented how wonderful my face looked! One specifically came up to me and asked what I was.. ...»
Jessie Sandford
The Pre-dissolved solution is excellent. Ferulic Acid is an amazing skincare ingredient (potent antioxidant, protects other sensitive antioxidants from light degradation, UV protection) but is absolutely ineffective if it isn't solubilized correctly. Makes adding to any Serum Base or w/o emulsion easy. Love using it (at 6%; so active 0.5%) with the Resveratrol Fluid (10%; active 1%) and Green Tea Extr for potent nighttime brightening treatment... ...»
James
Carla, Many medications can be and are applied topically by prescription. With that in mind, realize that this particular ingredient is wonderful but understand that this is indeed one of those that may create sensitivity with those already using topical hormones or just use sparingly and see how you respond. Sorry for the very late response..... ...»
Angela
Many thanks for the Silicone DM. This product is lovely quality; it is light, silky, and leaves no residue at all. I use it in the base recipe for a mouldable polymer that I then use to make a simulated 'Amber' for bead making. At the end of this process I have a silky, translucent polymer plus the most gorgeous hands in the studio ! My thanks again, Helen.. ...»
HELEN pEAKE
Very good product! Only been using it for a short time, its already made a difference. .. ...»
Bronwynne
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Quercetin

Quercetin is a molecule belonging to a class of complex organic compounds called flavonoids. Quercetin is produced by many plants, notably onions. The most important effect of this molecule is neutralizing free radicals. Quercetin can achieve this directly, due to its antioxidative properties, or by binding iron ions, which play a strong part in the accumulation of free radicals. Therefore, quercetin is an important component in UV-protective cosmeceuticals. It can also reduce the inflammation, darkening and synthesis of collagen-degrading enzymes, caused by UV exposure. Furthermore, quercetin has benefits for wound care, as it improves both healing of new wounds and subsequent scar formation. It even has a positive effect on the lifespan of cells, slowing down processes of cell ageing.

NOTE: To assist you with solubility issues, we now also sell Quercetin as two liquids: standardized pre-dissolved solution and standardized ethosome microemulsion. Just add the liquid to your cream and mix well.
  • 11% solution gives 1% Quercetin content in final product.
  • 31% solution gives 3% Quercetin content in final product.
  • 51% solution gives 5% Quercetin content in final product.

Key benefits of Quercetin in skin care:

  • Sun damage protection [3], [5]–[7]
  • Sun damage repair [3], [5]
  • Lightening & brightening [8]
  • Treat hyperpigmentation [8]
  • Anti-inflammatory [6], [7]
  • Antioxidant [1]–[4], [14]
  • Scar care [11]–[13]
  • Wound healing support [9], [10]
Product Code: BulkActives
Reward Points: 6
Assay: 99%. 9.9%. 0.99%
CAS#: 6151-25-3
Net weight: 30g /1.06oz & 50g / 1.76oz
Availability:
Standardized preDissolved solution 100g - Options In Stock
Standardized Powder 30g - Options In Stock
Price: $14.80
Reward Points: 570


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About Quercetin in DIY Skin Care

quercetin skin careFlavonoids are complex organic molecules, performing many diverse functions in plants, and possessing various benefits for human body. Quercetin is one of the most popular flavonoids, found in many plant-based foods [1]. It is particularly abundant in onions (can make up 0.1 % of their fresh weight), and is responsible for many of the health benefits of onion extracts [2]. In skincare, quercetin is most important for various aspects of UV protection, including anti-inflammatory and antioxidant effects. Additionally, as a component in onion extract, quercetin provides active support in wound healing and scar care.

UV exposure of the skin leads to generation of free radicals and inflammation. These processes lead to damage ranging from cosmetic defects (photoageing of skin) to pre-cancerous and cancerous skin lesions. Flavonoids have the possibility to neutralize this damage due to their antioxidant properties, and quercetin is one of the most potent flavonoids in this respect. Applying quercetin emulsion helps the natural defenses against free radicals – namely, it restores antioxidant glutathione levels [3]. Accumulation of free radicals is increased by iron ions. Quercetin has the ability to bind (chelate) this ions, thus reducing the speed of free radical production under damaging conditions [4].

Collagen degradation is another adverse effect of UV, as sunlight exposure enhances the synthesis of matrix metalloproteinase enzymes. This can also be avoided by using an emulsion with 0.5 % quercetine [5]. Furthermore, quercetin is known to inhibit the inflammatory signals, typically produced after UV exposure [6]. Applications of quercetin on UV-irradiated mouse skin reduced irritation, edema and leukocyte accumulation, typical signs of inflammation [7].

Surprisingly, quercetin applications also have a general anti-ageing effect on cells. It was found that cells treated with this flavonoid have increased life span and maintain features of young cells longer [8]. This effect is likely related to the antioxidant power of quercetin, as the treated cells were also more protected from oxidative stress. Finally, this compound also showed a whitening effect on cells by reducing melanin synthesis [8].

Quercetin has other applications in skin care as well. It was found that it helps skin recover after burns, including reduced inflammation, minimized damage and faster regeneration of hair follicles [9]. Even mouth ulcer healing is supported by applications of quercetin [10]. Since quercetin is the most abundant flavonoid in onion flesh, the medicinal uses of this plant’s extract reflect the benefits of quercetin. Namely, onion extract is used in scar care – its applications result in improved scar appearance and decreased size [11], [12]. Although treatment may take 2-3 months, the improvement in appearance is noted by both the volunteers and researchers. Even scars of hypertrophic type can be treated by this extract [13]. In these applications, onion extract is often combined with allantoin [11], [13]. Preliminary results from volunteer studies also indicate that quercetin has positive results on skin elasticity, moisturization and depth of wrinkles [8]. As an ingredient in creams, quercetin is stable and shows strong antioxidant activity even after 3 months of storage at high temperatures [14].
 

NOTE: To assist you with solubility issues, we now also sell Quercetin in two liquids: pre-dissolved solution and ethosome microemulsion. Just add the liquid to your cream and mix well, or add water and mix well.

Quercetin Standardized Powder

Assay: 99%
CAS#:  6151-25-3
INCI: Quercetin
Botanical Source: Sophorae Japonica  (Genistin, genistein, rutin, kaempferol and quercetin are important bioactive constituents in Sophorae Japonica)

Solubility: 1,3-Propanediol (heated)
Suggested percentage: 1 to 5% Quercetin in 90% 1,3-Propanedioll (heated)

Storage: Store in cool and dry place. Do not expose to heat or light
Country of origin for raw material: China
Country of manufacture: Taiwan

Quercetin Standardized Pre Dissolved Solution - 10%

Assay: 9.9% Quercetin
CAS#: 504-63-2, 61788-85-0, 6151-25-3
INCI: 1,3-Propanediol, PEG-40 Hydrogenated Castor Oil, Quercetin
Appearance: dark yellow liquid

Solubility: add to cream
Suggested percentage:
11% solution gives 1% Quercetin content in final product.
31% solution gives 3% Quercetin content in final product.
51% solution gives 5% Quercetin content in final product.

Storage: Store in fridge, do not freeze.
Country of origin for raw material: China
Country of manufacture: Taiwan
 

Quercetin Standardized Ethosome Solution - 1%

Assay: 0.99% Quercetin
CAS#:7732-18-5, 64-17-5, 504-63-2, 8002-43-5, 6151-25-3
INCI: Water, Ethyl Alcohol, 1,3-Propanediol, Lecithin, Quercetin
Appearance: dark yellow liquid

Solubility: add to cream or water
Suggested percentage:
51% Quercetin Ethosome Solution gives 0.5% Quercetin content in final product.
(NOTE: Ethosome-encapsulation largely reduces the amount of Quercetin required for effectiveness as compared to non-encapsulated pure Quercetin)

Storage: Store in fridge, do not freeze.
Country of origin for raw material: China
Country of manufacture: Taiwan
 
[1]          K. Kawabata, R. Mukai, and A. Ishisaka, “Quercetin and related polyphenols: new insights and implications for their bioactivity and bioavailability,” Food Funct., Mar. 2015.
[2]          J. Park, J. Kim, and M. K. Kim, “Onion flesh and onion peel enhance antioxidant status in aged rats,” J. Nutr. Sci. Vitaminol. (Tokyo), vol. 53, no. 1, pp. 21–29, Feb. 2007.
[3]          R. Casagrande, S. R. Georgetti, W. A. Verri, D. J. Dorta, A. C. dos Santos, and M. J. V. Fonseca, “Protective effect of topical formulations containing quercetin against UVB-induced oxidative stress in hairless mice,” J. Photochem. Photobiol. B, vol. 84, no. 1, pp. 21–27, Jul. 2006.
[4]          N. R. Perron and J. L. Brumaghim, “A review of the antioxidant mechanisms of polyphenol compounds related to iron binding,” Cell Biochem. Biophys., vol. 53, no. 2, pp. 75–100, 2009.
[5]          F. T. M. C. Vicentini, Y. M. Fonseca, D. L. Pitol, M. M. Iyomasa, M. V. L. B. Bentley, and M. J. V. Fonseca, “Evaluation of protective effect of a water-in-oil microemulsion incorporating quercetin against UVB-induced damage in hairless mice skin,” J. Pharm. Pharm. Sci. Publ. Can. Soc. Pharm. Sci. Société Can. Sci. Pharm., vol. 13, no. 2, pp. 274–285, 2010.
[6]          F. T. M. C. Vicentini, T. He, Y. Shao, M. J. V. Fonseca, W. A. Verri, G. J. Fisher, and Y. Xu, “Quercetin inhibits UV irradiation-induced inflammatory cytokine production in primary human keratinocytes by suppressing NF-κB pathway,” J. Dermatol. Sci., vol. 61, no. 3, pp. 162–168, Mar. 2011.
[7]          C. Caddeo, O. Díez-Sales, R. Pons, X. Fernàndez-Busquets, A. M. Fadda, and M. Manconi, “Topical anti-inflammatory potential of quercetin in lipid-based nanosystems: in vivo and in vitro evaluation,” Pharm. Res., vol. 31, no. 4, pp. 959–968, Apr. 2014.
[8]          N. Chondrogianni, S. Kapeta, I. Chinou, K. Vassilatou, I. Papassideri, and E. S. Gonos, “Anti-ageing and rejuvenating effects of quercetin,” Exp. Gerontol., vol. 45, no. 10, pp. 763–771, Oct. 2010.
[9]          A. A. Naumov and M. M. Potselueva, “[Beneficial action of the liposomal form of dihydroquercetin on the process of skin regeneration after thermal burn],” Tsitologiia, vol. 52, no. 4, pp. 311–316, 2010.
[10]        A. A. E.-M. M. Hamdy and M. A. E.-M. Ibrahem, “Management of aphthous ulceration with topical quercetin: a randomized clinical trial,” J. Contemp. Dent. Pract., vol. 11, no. 4, pp. E009–016, 2010.
[11]        G. H. Willital and J. Simon, “Efficacy of early initiation of a gel containing extractum cepae, heparin, and allantoin for scar treatment: an observational, noninterventional study of daily practice,” J. Drugs Dermatol. JDD, vol. 12, no. 1, pp. 38–42, Jan. 2013.
[12]        Z. D. Draelos, “The ability of onion extract gel to improve the cosmetic appearance of postsurgical scars,” J. Cosmet. Dermatol., vol. 7, no. 2, pp. 101–104, Jun. 2008.
[13]        A. Campanati, A. Savelli, L. Sandroni, B. Marconi, A. Giuliano, K. Giuliodori, G. Ganzetti, and A. Offidani, “Effect of allium cepa-allantoin-pentaglycan gel on skin hypertrophic scars: clinical and video-capillaroscopic results of an open-label, controlled, nonrandomized clinical trial,” Dermatol. Surg. Off. Publ. Am. Soc. Dermatol. Surg. Al, vol. 36, no. 9, pp. 1439–1444, Sep. 2010.
[14]        R. Casagrande, S. R. Georgetti, W. A. Verri, J. R. Jabor, A. C. Santos, and M. J. V. Fonseca, “Evaluation of functional stability of quercetin as a raw material and in different topical formulations by its antilipoperoxidative activity,” AAPS PharmSciTech, vol. 7, no. 1, p. E10, 2006.

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