About Alpha Bisabolol

Alpha Bisabolol, a derivative of M. chamomilla (German chamomile), is an optically active unsaturated sesquiterpene alcohol, obtained by extraction
from natural raw materials. Bisabolol is a natural occurring, versatile, active ingredient for the cosmetic industry.

Alpha Bisabolol helps administer active ingredients transdermally by enhancing skin penetration. Bisabolol is also found in some lotions for reducing wrinkles and acne.

The most important effects of Bisabolol are:

• Anti-inflammatory
• Anti-bacterial
• Anti-mycotic
• Anti-phlogistic
• Non-allergic

Bisabolol is a preferred active ingredient for protection against the recurring stresses of the environment on the skin. 

Applications for Bisabolol include acne treatment preparations, after shave products, baby care, body lotions & scrubs, hand lotions (anti-bacterial,) oral hygiene preparations, face and body moisturizers, as well as pre-sun and after-suncreams and lotions. Use levels range from 0.1% - 0.5% in formulations

Natural vs. Synthetic

Natural Alpha Bisabolol is 97% as active (-) alpha-bisabolol isomer.
Synthetic Alpha Bisabolol is 42.5% as active (-) alpha-bisabolol isomer.

Formulating chemists use 50% less natural alpha-bisabolol than synthetic alpha bisabolol to achieve the same results.

"Camomile has been used for centuries as an antiphlogistic for the skin and
mucous membranes. It was assumed in the past that the therapeutic effi-
cacy of camomile was due to its chamazulene content. However, investi-
gations carried out in recent years have shown that apart from chamazu-
lene, the (-)-alpha-bisabolol content, in particular, is responsible for the
antiphlogistic effect.

In a paper entitled "The antiphlogistic effect of alpha-bisabolol", a direct comparison was carried out between (±)-alpha-bisabolol rac. and (-)-alpha-bisabolol natural. using carrageenan oedema in rats, croton oil oedema in mice and UV erythema in guinea pigs as pharmacological models, to determine the
antierythemic and antiphlogistic effects.

The combined results of the three trials show that (-)-alpha-bisabolol nat. has approximately twice the effi-cacy of (±)-alpha-bisabolol. Further, (-)-alpha-bisabolol nat. has been shown to possess antiphlogistic properties in the treatment of UV-induced erythema on human skin. " BASF product documentation

BulkActives' Alpha Bisabolol is Natural Alpha Bisabolol

Alpha Bisabolol, a derivative of M. chamomilla (German chamomile), helps administer active ingredients transdermally by enhancing skin penetration. The most important effects of Bisabolol are its anti-inflammatory, anti-irritant, anti-bacterial, and non-allergenic properties.