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BulkActives are DIY skin care suppliers of skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and standardized botanical extracts for diy skin care products and homemade cosmetics.
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Attention: BulkActives is a part-time business.
Orders are processed on Saturdays and mailed on Mondays at the latest, usually earlier.
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NEW! Safe, mild and gentle SURFACTANTS for DIY facial wash, body wash & shampoo:
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Ascorbyl Glucoside (Stabilized Ascorbic Acid)
DISCLAIMER:Any statements about products sold by BulkActives have not been evaluated by the FDA. Products sold by BulkActives are not intended to be used as nutritional supplements. Products sold by BulkActives are not intended to diagnose, treat, cure, or prevent any disease.
Name: Ascorbic Acid 2-Glucoside (AAG2TM)
INCI: Ascorbyl Glucoside
Appearance: fine white powder
Suggested percentage: 2 %
pH: 2.1 -2.8 (at 2% in water)
Stability: highly stable in solution even at high temperatures and in the presence
of metal ions. Stable at pH 5-7
Storage: Cool, dry place. Do not freeze. Keep away from light and moisture!
Country of origin: Japan
Ascorbyl Glucoside suppresses melanin synthesis
When Ascorbyl Glucoside is converted to vitamin C and enters the cells it significantly reduces the production of melanin by inhibiting tyrosinase activity. This results in a reduction of Dopaquinone, an intermediate of melanin synthesis. Additionally it converts existing Dopaquinone to L-Dopa.
The hydroxyl group of the second carbon in ascorbic acid is highly reactive and plays an important role in the natural biologic activity, however, it can also be the site of inactivation and decomposition.
Ascorbyl Glucoside is produced from vitamin C and starch by using a natural enzymes which result in binding glucose to the hydroxyl group of the same reactive carbon of the ascorbic acid.
An enzyme releases vitamin C at the cellular surface and provides benefits over a sustained period of time.
Ascorbyl Glucoside is hydrolyzed by glucosidase, an enzyme present in the membrane of skin cells.
This process releases vitamin C in its natural active form. When vitamin C enters cells it results in significant well-documented biological responses.
Ascorbyl Glucoside has been demonstrated to be hydrolyzed over a prolonged period giving its beneficial physiological effects to the cells and tissues in a constant and sustained manner.
Ascorbyl Glucoside in Skin Care
Ascorbyl Glucoside lightens existing melanin
Ascorbyl Glucoside improves skin hyperpigmentation
Creams containing Ascorbyl Glucoside are beneficial for lightening skin pigmentation.
Sixteen female volunteers (37 to 55 years old) applied a face cream containing 2% of AA2G??twice a day to a hyperpigmented area of their face for a total of 90 days.
The areas were matched against pantone color samples and the brightness (L* value) of the areas were measured by a colorimeter on day 0, 45 and 90.
(*Significantly different from day 0 at <0.01)
Ascorbyl Glucoside suppresses damage to cells caused by UV irradiation
When Ascorbyl Glucoside is converted to vitamin C it can dramatically reduce the free radicals that result from UV irradiation of the skin, and significantly reduce cell damage.
Human skin fibroblasts were cultured for 1 day. Fibroblast samples were cultured a second day with or without 1mM AA2G??
The cells were irradiated with 20mJ/cm2 UVA and B radiation, and then cultured for 2 additional days.
The number of viable cells were determined. (*Significantly different from UV irradiated cells without AA2G??at <0.05)
Ascorbyl Glucoside promotes collagen synthesis
Collagen is a protein that plays an important role in the structure and firmness of skin. When Ascorbyl Glucoside is converted to vitamin C and enters the cells it promotes collagen synthesis of skin fibroblasts. Ascorbyl Glucoside maintains its effects for a sustained period of time, resulting in increasing benefits.
After cultivation of normal human skin fibroblasts for 1 day, the cells were cultured in the presence of vitamin C (0.2mM) or AA2G??(0.2mM) for 2-4 days.
The percentage of collagen to total protein was determined. (*Significantly different from control at <0.05, and # significantly different from vitamin C at <0.05).
Ascorbyl Glucoside improves wrinkles and roughness
Creams containing Ascorbyl Glucoside are highly beneficial for improving wrinkles and roughness of skin.
Sixteen female volunteers (37 to 55 years old) applied a face cream containing 2% of AA2G??twice a day for a total of 90 days to the outer corners of their eyes and cheek area.
Silicone replicas of the corner of the eyes and the other treated areas were taken on days 0, 45 and 90 and wrinkle depth and skin roughness were measured by profilometry.
(*Significantly different from day 0 at <0.01).