Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients,  for DIY skin care and cosmetics, and homemade skin care products. 

BulkActives are DIY skin care suppliers of skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and standardized botanical extracts for diy skin care products and homemade cosmetics.

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Attention: BulkActives is a part-time business.
Orders are processed on Saturdays and mailed on Mondays at the latest, usually earlier.

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CoEnzymeQ10 (CoQ10/ubiquinone) - pure powder!

Product details

 

Assay: 98% Appearance: orange powder.

Solubility: oil

Suggested percentage: 3%

 

Storage: Store in a cool and dry place. Store in well closed containers.

Country of Origin: China

CoQ10 is an anti-oxidant.  topical application might restore mitochondrial activity, increase energy production as ATP, plus reduce power needed to make new collagen.

 

"What can CoQ10 do for your skin? Theoretically speaking, CoQ10 (in a skin cream, for example) can be helpful.

 

In most people over thirty, levels of CoQ10 in the skin are below optimum, resulting in lesser ability to produce collagen, elastin and other important skin molecules.

 

Besides, CoQ10-depleted skin may be more prone to the damage by free radicals, which are particularly abundant in the skin since it is exposed to the elements.

 

Thus, CoQ10 may boost skin repair and regeneration and reduce free radical damage.

 

Furthermore, CoQ10 is a small molecule that can relatively easily penetrate into skin cells."Todorov, G., Can coenzyme Q10 help protect and repair your skin?, Smartskincare

CoEnzymeQ10 is most well known as an antioxidant. For topical application it is often used for that purpose, and for promoting collagen production. Some DIY skin care recipes also include it since it is said to protect against UV damage.

DISCLAIMER:Any statements about products sold by BulkActives have not been evaluated by the FDA.  Products sold by BulkActives are not intended to be used as nutritional supplements. Products sold by BulkActives are not intended to diagnose, treat, cure, or prevent any disease.

BulkActives: ingredients for DIY skin care and cosmetics
CoQ10 / CoEnzyme Q10





CoQ10 in skin care:

 

  • antioxidant
  • collagen production
  • sun damage protection

References (full abstracts here)

 

11: Tournas JA, Lin FH, Burch JA, Selim MA, Monteiro-Riviere NA, Zielinski JE, Pinnell SR. Ubiquinone, idebenone, and kinetin provide ineffective photoprotection to skin when compared to a topical antioxidant combination of vitamins C and E with ferulic acid. J Invest Dermatol. 2006 May;126(5):1185-7. PubMed PMID: 16528359.


 

10: Muta-Takada K, Terada T, Yamanishi H, Ashida Y, Inomata S, Nishiyama T, Amano  S. Coenzyme Q10 protects against oxidative stress-induced cell death and enhances the synthesis of basement membrane components in dermal and epidermal cells. Biofactors. 2009 Sep-Oct;35(5):435-41. PubMed PMID: 19753652. 

9: Choi BS, Song HS, Kim HR, Park TW, Kim TD, Cho BJ, Kim CJ, Sim SS. Effect of coenzyme Q10 on cutaneous healing in skin-incised mice. Arch Pharm Res. 2009 Jun;32(6):907-13. Epub 2009 Jun 26. PubMed PMID: 19557369. 

8: Puizina-Ivi? N. Skin aging. Acta Dermatovenerol Alp Panonica Adriat. 2008 Jun;17(2):47-54. Review. PubMed PMID: 18709289. 

7: Prahl S, Kueper T, Biernoth T, Wöhrmann Y, Münster A, Fürstenau M, Schmidt M,  Schulze C, Wittern KP, Wenck H, Muhr GM, Blatt T. Aging skin is functionally anaerobic: importance of coenzyme Q10 for anti aging skin care. Biofactors. 2008;32(1-4):245-55. PubMed PMID: 19096122. 

6: Inui M, Ooe M, Fujii K, Matsunaka H, Yoshida M, Ichihashi M. Mechanisms of inhibitory effects of CoQ10 on UVB-induced wrinkle formation in vitro and in vivo. Biofactors. 2008;32(1-4):237-43. PubMed PMID: 19096121.  

5: Fuller B, Smith D, Howerton A, Kern D. Anti-inflammatory effects of CoQ10 and  colorless carotenoids. J Cosmet Dermatol. 2006 Mar;5(1):30-8. PubMed PMID: 17173569. 

4: Passi S, De Pit? O, Grandinetti M, Simotti C, Littarru GP. The combined use of oral and topical lipophilic antioxidants increases their levels both in sebum and stratum corneum. Biofactors. 2003;18(1-4):289-97. PubMed PMID: 14695946. 

3: Hojerová J. [Coenzyme Q10--its importance, properties and use in nutrition and cosmetics]. Ceska Slov Farm. 2000 May;49(3):119-23. Review. Slovak. PubMed PMID:  10953455. 

2: Blatt T, Mundt C, Mummert C, Maksiuk T, Wolber R, Keyhani R, Schreiner V, Hoppe U, Schachtschabel DO, Stäb F. [Modulation of oxidative stresses in human aging skin]. Z Gerontol Geriatr. 1999 Apr;32(2):83-8. German. PubMed PMID: 10408011. 

1: Hoppe U, Bergemann J, Diembeck W, Ennen J, Gohla S, Harris I, Jacob J, Kielholz J, Mei W, Pollet D, Schachtschabel D, Sauermann G, Schreiner V, Stäb F,  Steckel F. Coenzyme Q10, a cutaneous antioxidant and energizer. Biofactors. 1999;9(2-4):371-8. Review. PubMed PMID: 10416055.   

CoQ10 in skin care - research

 

Topically applied CoQ10 may:

 

  • prevent or reduce UVA and UVB sun damage: [6] [5] [2] [1]

  • act as an anti- oxidant: [10] [9] [8] [3] [2]

  • increase cellular energy production: [10] [4]

  • act as an anti-inflammatory: [9] [7] [5]

  • improve mitochondrial function: [7]

 

Note that Pinnell et al. [11] claim that CoQ10 is NOT as effective for sun protection as Pinnell?�s Vitamin C+E+Ferulic. 

 

At BuklkActives we are not a big fan of Idebenone or CoQ10 for topical sunprotection as neither are very soluble and bio available.

 

We strongly suggest that Vitamin C be the main weapon in your fight against sun damage, and that CoQ10 or Idebenone are used at night to help increase cellular energy production.