Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients,  for DIY skin care and cosmetics, and homemade skin care products. 

BulkActives are DIY skin care suppliers of skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and standardized botanical extracts for diy skin care products and homemade cosmetics.

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Idebenone

Product details

 

 

Solubility: non-denatured ethanol, Propylene glycol (may require gentle heating)

Suggested percentage: .5% to 1%


Storage: Store in cool and dry place. Keep away from direct strong light and heat.
Country of origin: China

 

"Idebenone is closely related to CoQ10 in its structure. It can replace CoQ10 in the process of cellular energy production and, just as CoQ10, idebenone is also an antioxidant.

 

There are some important distinctions though. Its cellular distribution and antioxidant profile are somewhat different. This makes idebenone superior to CoQ10 in neutralizing some types of free radicals and inferior in fighting other types.

 

Notably, idebnone is more effective than CoQ10 in protecting cells from the free radical damage resulting from reduced blood flow.

 

On the other hand, idebenone appears more conducive than CoQ10 to certain types of noxious free-radical leakage in the cell's mitochondria. Unfortunately, there have been very few studies directly comparing CoQ10 and idebenone in the treatment of various conditions." Todorov, G., Idebenone: a powerful wrinkle-fighter, a copy-cat or both? Smartskincare.com

Read more about Idebenone:

 

Idebenone has qualities that make it a good choice as an antioxidant. Idebenone also promotes cellular energy production. Since it is closely related to CoQ10 it may be used as replacement for CoQ10 in many recipes.

DISCLAIMER:Any statements about products sold by BulkActives have not been evaluated by the FDA.  Products sold by BulkActives are not intended to be used as nutritional supplements. Products sold by BulkActives are not intended to diagnose, treat, cure, or prevent any disease.

BulkActives: ingredients for DIY skin care and cosmetics
Idebenone





Idebenone in skin care:

 

  • antioxidant,
  • cellular energy production
Idebenone in skin care - research

 

Topically applied Idebenone may:

 

  • prevent or reduce UVA and UVB sun damage: [2]

  • act as an anti- oxidant: [1]

  • increase cellular energy production: as a synthetic analog of Co-Q10

References (full abstracts here)

 

3: Tournas JA, Lin FH, Burch JA, Selim MA, Monteiro-Riviere NA, Zielinski JE, Pinnell SR. Ubiquinone, idebenone, and kinetin provide ineffective photoprotection to skin when compared to a topical antioxidant combination of vitamins C and E with ferulic acid. J Invest Dermatol. 2006 May;126(5):1185-7. PubMed PMID: 16528359.

2: McDaniel DH, Neudecker BA, DiNardo JC, Lewis JA 2nd, Maibach HI. Clinical efficacy assessment in photodamaged skin of 0.5% and 1.0% idebenone. J Cosmet Dermatol. 2005 Sep;4(3):167-73. PubMed PMID: 17129261. 

1: McDaniel DH, Neudecker BA, DiNardo JC, Lewis JA 2nd, Maibach HI. Idebenone: a  new antioxidant - Part I. Relative assessment of oxidative stress protection capacity compared to commonly known antioxidants. J Cosmet Dermatol. 2005 Jan;4(1):10-7. PubMed PMID: 17134415.    

Note that Pinnell et al. [1] claim that Idebenone is NOT as effective for sun protection as Pinnell?�s Vitamin C+E+Ferulic. 

 

At BulkActives we are not a big fan of Idebenone or CoQ10 for topical sunprotection, as neither are very soluble and bio available.

 

We strongly suggest that Vitamin C be the main weapon in your fight against sun damage, and that CoQ10 or Idebenone are used at night to help increase cellular energy production.