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BulkActives are DIY skin care suppliers of skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and standardized botanical extracts for diy skin care products and homemade cosmetics.
New & Updates
Attention: BulkActives is a part-time business.
Orders are processed on Saturdays and mailed on Mondays at the latest, usually earlier.
Free original software: Recipe creator
NEW! Safe, mild and gentle SURFACTANTS for DIY facial wash, body wash & shampoo:
Botanical Source: Sophorae Japonica "Genistin, genistein, rutin, kaempferol and quercetin are important bioactive constituents in Sophorae Japonica" Read more
Solubility: Dimethyl isosorbide, non-denatured ethanol, propylene glycol
Suggested percentage: 1% in 6% propylene glycol (as described in the full text of the UVB study quoted below)
Stability: The product is stable: 'Evaluation of Functional Stability of Quercetin as a Raw Material and in Different Topical Formulations by its Antilipoperoxidative Activity' Read PDF
Conditions of Instability: Excess heat
Incompatibility with various substances: Reactive with oxidizing agents, acids.
Storage: Store in cool and dry place. Keep away from direct strong light and heat.
Country of origin: China
Can a Flavonoid, Quercetin, Be an Effective Topical Acne Medication?
Paige N. Dubin, CALIFORNIA STATE SCIENCE FAIR, project number: S1414
" topical Quercetin solution for acne proved to be a tremendous success in decreasing inflammatory acne lesions and decreasing the bacterial count on facial skin of all my acne subjects. " Read more (PDF)
DISCLAIMER:Any statements about products sold by BulkActives have not been evaluated by the FDA. Products sold by BulkActives are not intended to be used as nutritional supplements. Products sold by BulkActives are not intended to diagnose, treat, cure, or prevent any disease.
Polyphenols & Flavonoids
Polyphenols comprise a dynamic group of approximately 8,000 compounds that are widely distributed in plants used for food.
Within the class of polyphenols are the flavonoids, naturally occurring plant pigments that are also known as bioflavonoids.
Quercetin belongs to a group of plant pigments called flavonoids that give many fruits, flowers, and vegetables their color.
Flavonoids impart color to many fruits, vegetables, and flowers, and have also been found to possess numerous health benefits
Flavonoids, such as quercetin, are antioxidants, they scavenge damaging particles in the body known as free radicals, which damage cell membranes, tamper with DNA, and even cause cell death.
Antioxidants can neutralize free radicals and may reduce or even help prevent some of the damage they cause.
Onion Extract Gel references (full abstracts here)
17: Perez OA, Viera MH, Patel JK, Konda S, Amini S, Huo R, Zell D, Tadicherla S, Berman B. A comparative study evaluating the tolerability and efficacy of two topical therapies for the treatment of keloids and hypertrophic scars. J Drugs Dermatol. 2010 May;9(5):514-8. PubMed PMID: 20480794. preexisting
16: Koc E, Arca E, Surucu B, Kurumlu Z. An open, randomized, controlled, comparative study of the combined effect of intralesional triamcinolone acetonide and onion extract gel and intralesional triamcinolone acetonide alone in the treatment of hypertrophic scars and keloids. Dermatol Surg. 2008 Nov;34(11):1507-14. Epub 2008 Sep 15. PubMed PMID: 18798752. preexisting
15: Draelos ZD. The ability of onion extract gel to improve the cosmetic appearance of postsurgical scars. J Cosmet Dermatol. 2008 Jun;7(2):101-4. PubMed PMID: 18482012. surgery
14: Hosnuter M, Payasli C, Isikdemir A, Tekerekoglu B. The effects of onion extract on hypertrophic and keloid scars. J Wound Care. 2007 Jun;16(6):251-4. PubMed PMID: 17722521. preexisting
13: Ho WS, Ying SY, Chan PC, Chan HH. Use of onion extract, heparin, allantoin gel in prevention of scarring in chinese patients having laser removal of tattoos: a prospective randomized controlled trial. Dermatol Surg. 2006 Jul;32(7):891-6. PubMed PMID: 16875470. surgery
12: Chung VQ, Kelley L, Marra D, Jiang SB. Onion extract gel versus petrolatum emollient on new surgical scars: prospective double-blinded study. Dermatol Surg. 2006 Feb;32(2):193-7. PubMed PMID: 16442038. surgery
Quercetin in skin care - research
Topically applied Quercetin may:
prevent or reduce UVA and UVB sun damage:     
Quercetin References (full abstracts here)
11: Vicentini FT, Simi TR, Del Ciampo JO, Wolga NO, Pitol DL, Iyomasa MM, Bentley MV, Fonseca MJ. Quercetin in w/o microemulsion: in vitro and in vivo skin penetration and efficacy against UVB-induced skin damages evaluated in vivo. Eur J Pharm Biopharm. 2008 Aug;69(3):948-57. Epub 2008 Jan 20. PubMed PMID: 18304790.
10: Casagrande R, Georgetti SR, Verri WA Jr, Dorta DJ, dos Santos AC, Fonseca MJ. Protective effect of topical formulations containing quercetin against UVB-induced oxidative stress in hairless mice. J Photochem Photobiol B. 2006 Jul 3;84(1):21-7. Epub 2006 Feb 21. PubMed PMID: 16495072.
9. Maha F. El Goweini, MD*; Nagwa M. Nour El Din, MD. Effect of Quercetin on Excessive Dermal ScarringEgyptian Dermatology Online Journal 1 (1): 5, June 2005
8: Phan TT, Lim IJ, Chan SY, Tan EK, Lee ST, Longaker MT. Suppression of transforming growth factor beta/smad signaling in keloid-derived fibroblasts by quercetin: implications for the treatment of excessive scars. J Trauma. 2004 Nov;57(5):1032-7. PubMed PMID: 15580028.
7: Phan TT, Lim IJ, Sun L, Chan SY, Bay BH, Tan EK, Lee ST. Quercetin inhibits fibronectin production by keloid-derived fibroblasts. Implication for the treatment of excessive scars. J Dermatol Sci. 2003 Dec;33(3):192-4. PubMed PMID: 14643528.
6: Phan TT, Sun L, Bay BH, Chan SY, Lee ST. Dietary compounds inhibit proliferation and contraction of keloid and hypertrophic scar-derived fibroblasts in vitro: therapeutic implication for excessive scarring. J Trauma. 2003 Jun;54(6):1212-24. PubMed PMID: 12813346.
5: Phan TT, See P, Tran E, Nguyen TT, Chan SY, Lee ST, Huynh H. Suppression of insulin-like growth factor signalling pathway and collagen expression in keloid-derived fibroblasts by quercetin: its therapeutic potential use in the treatment and/or prevention of keloids. Br J Dermatol. 2003 Mar;148(3):544-52. PubMed PMID: 12653748.
4: Kahraman A, Inal ME. Protective effects of quercetin on ultraviolet A light-induced oxidative stress in the blood of rat. J Appl Toxicol. 2002 Sep-Oct;22(5):303-9. PubMed PMID: 12355559.
3: Erden Inal M, Kahraman A, Köken T. Beneficial effects of quercetin on oxidative stress induced by ultraviolet A. Clin Exp Dermatol. 2001 Sep;26(6):536-9. PubMed PMID: 11678884.
2: Erden Inal M, Kahraman A. The protective effect of flavonol quercetin against ultraviolet a induced oxidative stress in rats. Toxicology. 2000 Nov 23;154(1-3):21-9. PubMed PMID: 11118667.
1: Skaper SD, Fabris M, Ferrari V, Dalle Carbonare M, Leon A. Quercetin protects cutaneous tissue-associated cell types including sensory neurons from oxidative stress induced by glutathione depletion: cooperative effects of ascorbic acid. Free Radic Biol Med. 1997;22(4):669-78. PubMed PMID: 9013129.