Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients,  for DIY skin care and cosmetics, and homemade skin care products. 

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BulkActives are DIY skin care suppliers of skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and standardized botanical extracts for diy skin care products and homemade cosmetics.

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Attention: BulkActives is a part-time business.
Orders are processed on Saturdays and mailed on Mondays at the latest, usually earlier.

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Polygonum cuspidatum Resveratrol for diy skin care

Resveratrol 98% (Trans-resveratrol 98%)

Product details

CAS#: 501-36-0

Assay: 98%

Botanical source: Polygonum cuspidatum Sieb.
(Japanese Knotweed,Fallopia japonica, Polygonum cuspidatum, Reynoutria japonica).

Color: off white, cream

Mesh size: 100% through 80 mesh screen.

Solubility: non-denatured ethanol

Suggested percentage: No data available - up to customer's discretion.
Storage: Cool, dry place. Do not freeze. Keep away from light and moisture!
Country of origin: China

Manufacturer's data:  Resveratrol 98% COA

About BulkActives' Resveratrol

Resveratrol in skin care - research

 

Topically applied resveratrol may:

 

  • act as an anti-inflammatory: [9] [8] [7]

  • act as an anti-oxidant: [3]

  • lighten and brighten skin (treat melsama/hyper pigmentation):  [1]

  • repair and treat sun damage:  [11] [8] [6] [4]

 

Trans-resveratrol 98% is the most bio active form of resveratrol available. Resveratrol is used in many home made skin care recipes. It is useful as an antioxidant, an anti-inflammatory, for skin lightening & brightening, and for sun damage repair. Resveratol is a natural ingredient that can be found in many plants. The product we sell comes from Giant Knotweed.

"Both Japanese knotweed and giant knotweed are important concentrated sources of resveratrol, replacing grape byproducts. Many large supplement sources of Resveratrol now use Japanese knotweed and use its scientific name in the supplement labels." Read more here  and Resveratrol Isolated from Polygonum cuspidatum Root Prevents Tumor Growth

Our trans-resveratrol is extracted from the roots of the Giant Knotweed, and is standardized at 98%

 

"Resveratrol is produced by several plants, apparently for its antifungal properties. It is found in widely varying amounts in grapes (primarily the skins), raspberries, mulberries, in peanuts, berries of Vaccinium species, including blueberries, bilberries, and cranberries, some pines, such as Scots pine and eastern white pine, and the roots and stalks of giant knotweed and Japanese knotweed, called hu zhang in China. Resveratrol was first isolated from an extract of the Peruvian legume Cassia quinquangulata in 1974." Read more

DISCLAIMER:Any statements about products sold by BulkActives have not been evaluated by the FDA.  Products sold by BulkActives are not intended to be used as nutritional supplements. Products sold by BulkActives are not intended to diagnose, treat, cure, or prevent any disease.

BulkActives: ingredients for DIY skin care and cosmetics
Trans-resveratrol 98%


In stock:YES



Resveratrol in skin care:

 

  • antioxidant
  • anti-inflammatory
  • lightening & brightening
  • sun damage repair
 Although resvertarol may repair and treat sun damage ( [11] [8] [6] [4]) it should not be used during the day as a preventative, as it is suggested that resveratrol may react negatively with the UVA in sunlight [7].

References (full abstracts here)

 

11: Roy P, Kalra N, Prasad S, George J, Shukla Y. Chemopreventive potential of resveratrol in mouse skin tumors through regulation of mitochondrial and PI3K/AKT signaling pathways. Pharm Res. 2009 Jan;26(1):211-7. Epub 2008 Sep 13. PubMed PMID: 18791811.  

10: Hung CF, Lin YK, Huang ZR, Fang JY. Delivery of resveratrol, a red wine polyphenol, from solutions and hydrogels via the skin. Biol Pharm Bull. 2008 May;31(5):955-62. PubMed PMID: 18451526.  

9: Bralley EE, Greenspan P, Hargrove JL, Wicker L, Hartle DK. Topical anti-inflammatory activity of Polygonum cuspidatum extract in the TPA model of mouse ear inflammation. J Inflamm (Lond). 2008 Feb 8;5:1. PubMed PMID: 18261214;  PubMed Central PMCID: PMC2267461. 

8: Kundu JK, Shin YK, Surh YJ. Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-kappaB and AP-1 as prime targets. Biochem Pharmacol. 2006 Nov 30;72(11):1506-15. Epub 2006 Sep 26. Review. PubMed PMID: 16999939. 

7: Seve M, Chimienti F, Devergnas S, Aouffen M, Douki T, Chantegrel J, Cadet J, Favier A. Resveratrol enhances UVA-induced DNA damage in HaCaT human keratinocytes. Med Chem. 2005 Nov;1(6):629-33. PubMed PMID: 16787346.  

6: Reagan-Shaw S, Afaq F, Aziz MH, Ahmad N. Modulations of critical cell cycle regulatory events during chemoprevention of ultraviolet B-mediated responses by resveratrol in SKH-1 hairless mouse skin. Oncogene. 2004 Jul 1;23(30):5151-60. PubMed PMID: 15122319. 

5: Docherty JJ, Smith JS, Fu MM, Stoner T, Booth T. Effect of topically applied resveratrol on cutaneous herpes simplex virus infections in hairless mice. Antiviral Res. 2004 Jan;61(1):19-26. PubMed PMID: 14670590. 

4: Afaq F, Adhami VM, Ahmad N. Prevention of short-term ultraviolet B radiation-mediated damages by resveratrol in SKH-1 hairless mice. Toxicol Appl Pharmacol. 2003 Jan 1;186(1):28-37. PubMed PMID: 12583990. 

3: Sen CK, Khanna S, Gordillo G, Bagchi D, Bagchi M, Roy S. Oxygen, oxidants, and antioxidants in wound healing: an emerging paradigm. Ann N Y Acad Sci. 2002 May;957:239-49. Review. PubMed PMID: 12074976. 

2: Kimura Y, Okuda H. Resveratrol isolated from Polygonum cuspidatum root prevents tumor growth and metastasis to lung and tumor-induced neovascularization in Lewis lung carcinoma-bearing mice. J Nutr. 2001 Jun;131(6):1844-9. PubMed PMID: 11385077. 

1: Bernard P, Berthon JY. Resveratrol: an original mechanism on tyrosinase inhibition. Int J Cosmet Sci. 2000 Jun;22(3):219-26. PubMed PMID: 18503477.