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BulkActives are DIY skin care suppliers of skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and standardized botanical extracts for diy skin care products and homemade cosmetics.
New & Updates
Attention: BulkActives is a part-time business. Orders are processed on Saturdays and mailed on Mondays.
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New products
Ultra Low Molecular Weight NaH
Out of stock:
Idebenone, MAP, ALA. Green Tea (EGCG), Oat Beta Glucan, Gelmaker, Polysorbate 80, Salicylic acid
Saw Palmetto
Is an active ingredient for DIY skin care and homemade cosmetics from BulkActives.
Product details
Assay: Fatty acids 25.25% Botanical source: Serenoa Repens Part used: Fruit
Suggested percentage: No data available - up to customer's discretion.
Storage: Cool, dry place. Do not freeze. Keep away from
light and moisture!
Country of origin: China
Manufacturer's data: Saw Palmetto COA
About Saw palmetto
"Saw Palmetto, Serenoa repens, is the sole species currently classified in the genus Serenoa. It has been known by a number of synonyms, including Sabal serrulatum, under which name it still often appears in alternative medicine. It is a small palm, normally reaching a height of around 2-4 m. Its trunk is sprawling, and it grows in clumps or dense thickets in sandy coastal lands or as undergrowth in pine woods or hardwood hammocks. Erect stems or trunks are rarely produced but are found in some populations. It is endemic to the southeastern United States, most commonly along the Atlantic and Gulf coastal plains, but also as far inland as southern Arkansas." Read more
Saw Palmetto research
A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia.
Prager N, Bickett K, French N, Marcovici G., Clinical Research and Development Network, Aurora, CO, USA.
BACKGROUND: Androgenetic alopecia (AGA) is characterized by the structural miniaturization of androgen-sensitive hair follicles in susceptible individuals and is anatomically defined within a given pattern of the scalp. Biochemically, one contributing factor of this disorder is the conversion of testosterone (T) to dihydrotestosterone (DHT) via the enzyme 5-alpha reductase (5AR). This metabolism is also key to the onset and progression of benign prostatic hyperplasia (BPH). Furthermore, AGA has also been shown to be responsive to drugs and agents used to treat BPH. Of note, certain botanical compounds have previously demonstrated efficacy against BPH. Here, we report the first example of a placebo-controlled, double-blind study undertaken in order to examine the benefit of these botanical substances in the treatment of AGA.
OBJECTIVES: The goal of this study was to test botanically derived 5AR inhibitors, specifically the liposterolic extract of Serenoa repens (LSESr) and beta-sitosterol, in the treatment of AGA.
Subjects: Included in this study were males between the ages of 23 and 64 years of age, in good health, with mild to moderate AGA.
RESULTS: The results of this pilot study showed a highly positive response to treatment. The blinded investigative staff assessment report showed that 60% of (6/10) study subjects dosed with the active study formulation were rated as improved at the final visit.
CONCLUSIONS: This study establishes the effectiveness of naturally occurring 5AR inhibitors against AGA for the first time, and justifies the expansion to larger trials. Read more
Threre is only one study on the use of Saw Palmetto as a baldness treatment: Prager N; Bickett K, French N, Marcovici G (2002 Apr 8). "A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia.". J Altern Complement Med 8 (2): 143-152., there are no further independent studies on this.
