| Product | water | Arlasolve DMI (Dimethyl isosorbide) | glycerin | oil | ethanol 95% | surfactant | propylene glycol | polysorbate 80 | cream/lotion | silicone base | references |
| Allantoin | Yes, 0.5% at 25 C | No | No | No | No | No | No | No | ISPcorp Solubility dataISPcorp Formulating With Allantoin | ||
| Alpha Lipoic Acid (RS-ALA) |
No | Yes | Yes | Yes | dissolves well in oily cream | ||||||
| Ammonium Glycyrrhizae (Liquorice extract - white) | Yes | Yes | Yes | ||||||||
| Yes | Yes | Yes | No | Yes, high water content | Disperses well | Anhydrous C (in silicone) | |||||
| Ascorbyl Tetraisopalmitate / Tetrahexyldecyl Ascorbate | No | No | Yes | Yes | Yes | Yes | Yes | Yes | |||
| Yes, stir well to dissolve lumps. | Yes | Yes | No | best to mix with water first | |||||||
| Yes, mix well in warm water. Use double boiler or microwave, do not boil solution. | No | No | No | No | No | best to mix with water first | No | ||||
| No "I am making my 2% SA serum with aloe vera. I heat the aloe vera, then add the SA and stir it, I let it sit for couple of hours while stirring as many times as I remember, then I buffer it with baking soda to bring the PH to the desired level. " |
No | Yes | Yes | Dissolves well in commercial facial cleansers | |||||||
| No | Yes | Yes | Yes | disperses grainy | Ethel Acetate Hydrotropic solubilization of total boswellic acids |
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| L-Carnitine | Yes | Yes | Yes, can be a bit grainy if not enough water content.Microwave boost solves this | ||||||||
| Coconut endosperm | Yes | ||||||||||
| No | difficult, can form soft sticky lumps | Yes An alternative would be to add a small amount of your base cream with your ethanol content. |
disperses grainy | ||||||||
| CoQ10 | No | No | Yes | ||||||||
| DMAE Bitartrate | Yes, may need warm water | Yes | Yes | No | |||||||
| Dipotassium Glycyrrhizinate (Liquorice extract - white) | Yes | Yes | Yes | ||||||||
| Ellagic Acid | Slight, but now requires less ethanol or glycol to dissolve. | Yes | |||||||||
| Ferulic
Acid (natural) |
slight | Slight, but now requires less ethanol or glycol to dissolve. | Yes | disperses a little grainy | |||||||
| GABA | Yes, warm water or microwave boost | ||||||||||
| Gamma oryzanol | No | Yes | disperses well in oily cream | MSDS | |||||||
| Glucosamine, N-acetyl-D | Yes | Yes | |||||||||
| Ginkgo Biloba | Yes | best to mix with water first | |||||||||
| Glycyrrhizinic acid (Liquorice extract - white) | no | yes | |||||||||
| slight | Yes | Yes | Yes | disperses grainy and sticky | MSDS | ||||||
|
Green Tea extract (EGCG) |
Yes | No | can be sticky | ||||||||
| Horsetail powder | No | No | No | ||||||||
| Yes | Yes, but too much will make it feel like 'snot.' | ||||||||||
| Yes | Yes | dissolves well in oily cream (VERY strong color) | |||||||||
| Jiaogulan (Gynostemma) | Yes | ||||||||||
| No | Yes | Yes | Yes | ware alcohol, mineral oil and esters | |||||||
| Magnesium
ascorbyl phosphate (MAP) |
Yes, make a paste, stir well to dissolve lumps | No | |||||||||
| Yes | Yes | Yes, can be a bit grainy if not enough water content. Microwave boost solves this | |||||||||
| Pine Bark extract | Yes
(99%) |
COA | |||||||||
| disperses
slightly grainy SAS suggest adding a few drops to make a paste. add the Pomegranate extract at a temp of 40 C or 104 F and mix with a mixer." |
disperses slightly grainy | Yes | |||||||||
| very slight in hot water | Yes | No | Yes | ||||||||
| Resveratrol | Slight, but now requires less ethanol or glycol to dissolve | Yes | Yes | ||||||||
| Saw Palmetto | |||||||||||
| No | "I've just tried dissolving it in glycerin and it dissolves 100%. Useful for people who want an oil free serum or cream." | "I found that the milk thistle extract dissolved completely in oil. I dissolved 1/4 tsp of the Silymarin in 1 tsp of sesame oil. 95% dissolved almost immediately. After leaving it to sit for 5 minutes I found it had completely dissolved, leaving me with a mustard colored oil with No grainy residue. Simply added it to my night cream. I have had difficulty getting it to dissolve in either warm water or alcohol." | Yes | disperses | |||||||
| Yes | Yes | Yes | |||||||||
| White Willow - bark extract | No | Yes | Yes | ||||||||
| Wild
Yam diosgenin |
Yes | Yes | |||||||||