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BulkActives are DIY skin care suppliers of skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and standardized botanical extracts for diy skin care products and homemade cosmetics.

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Soyisoflavones for DIY skin care from BulkActives

Soy Isoflavones 40%

Product details

 

 

Assay: Total Isoflavones 40%

(DAIDZIN, GLYCITIN, GENISTIN, DAIDZEIN, GLYCITEIN, GENISTEIN)

Botanical Source: Soybean
Solubility: water, non-denatured ethanol

Suggested percentage: 3% to 5%

Storage: Store in cool and dry place. Keep away from direct strong light and heat.
Country of origin: China

Manufacturer's Data: Soy Isoflavones COA

Read more about the benefits of Soy Isoflavones
on page 10 of this article:

Cutaneous photodamage, oxidative stress, and
topical antioxidant protection

Soy Isoflavones 40% has properties that make it useful for:  antioxidant recipes, as an anti-inflammatory, skin lightening & skin brightening formulations, and to protect against sun damage.

Soy Isoflavones in skin care - research

 

Topically applied soy isoflavones may:

 

  • act as an anti oxidant: [14] [10] [9] [8] [7] [6] [2]

  • prevent or reduce UVA/UVB damage:  [16] [15] [14] [13] [11] [10] [9] [8] [7] [6] [2]

  • act as an anti-inflammatory: [15] [11] [6]

  • increase hyaluronic acid production: [5]

  • lighten and brighten skin (treat melsama/hyper pigmentation): [4] [3] [1]

BulkActives: ingredients for DIY skin care and cosmetics
Soy isoflavones 40%


In stock:YES



Soy Isoflavones in skin care:

 

  • antioxidant
  • anti-inflammatory
  • lightening & brightening
  • sun damage protection
  • stimulate HA production
References  (full abstracts here )

 

17: Chadha G, Sathigari S, Parsons DL, Jayachandra Babu R. In vitro percutaneous absorption of genistein from topical gels through human skin. Drug Dev Ind Pharm. 2011 May;37(5):498-505. Epub 2010 Dec 3. PubMed PMID: 21126208.

 

16: Lee DE, Lee KW, Byun S, Jung SK, Song N, Lim SH, Heo YS, Kim JE, Kang NJ, Kim  BY, Bowden GT, Bode AM, Lee HJ, Dong Z. 7,3',4'-Trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet B-induced skin  cancer by targeting Cot and MKK4. J Biol Chem. 2011 Apr 22;286(16):14246-56. Epub 2011 Mar 4. PubMed PMID: 21378167; PubMed Central PMCID: PMC3077626.

 

15: Bandara M, Arun SJ, Allanson M, Widyarini S, Chai Z, Reeve VE. Topical

isoflavonoids reduce experimental cutaneous inflammation in mice. Immunol Cell Biol. 2010 Oct;88(7):727-33. Epub 2010 Mar 9. PubMed PMID: 20212509.

 

14: Huang CC, Hsu BY, Wu NL, Tsui WH, Lin TJ, Su CC, Hung CF. Anti-photoaging effects of soy isoflavone extract (aglycone and acetylglucoside form) from soybean cake. Int J Mol Sci. 2010;11(12):4782-95. Epub 2010 Nov 24. PubMed PMID:  21614173; PubMed Central PMCID: PMC3100816.

 

13: Chiu TM, Huang CC, Lin TJ, Fang JY, Wu NL, Hung CF. In vitro and in vivo

anti-photoaging effects of an isoflavone extract from soybean cake. J

Ethnopharmacol. 2009 Oct 29;126(1):108-13. Epub 2009 Aug 11. PubMed PMID: 19679176.

 

12: Moraes AB, Haidar MA, Soares Júnior JM, Simões MJ, Baracat EC, Patriarca MT. The effects of topical isoflavones on postmenopausal skin: double-blind and randomized clinical trial of efficacy. Eur J Obstet Gynecol Reprod Biol. 2009 Oct;146(2):188-92. Epub 2009 May 17. PubMed PMID: 19450919.

 

11: Hwang JT, Lee YK, Shin JI, Park OJ. Anti-inflammatory and anticarcinogenic

effect of genistein alone or in combination with capsaicin in TPA-treated rat

mammary glands or mammary cancer cell line. Ann N Y Acad Sci. 2009

Aug;1171:415-20. PubMed PMID: 19723084.

 

10: Huang ZR, Hung CF, Lin YK, Fang JY. In vitro and in vivo evaluation of topical delivery and potential dermal use of soy isoflavones genistein and daidzein. Int  J Pharm. 2008 Nov 19;364(1):36-44. Epub 2008 Aug 13. PubMed PMID: 18761396.

 

9: Lin JY, Tournas JA, Burch JA, Monteiro-Riviere NA, Zielinski J. Topical

isoflavones provide effective photoprotection to skin. Photodermatol Photoimmunol Photomed. 2008 Apr;24(2):61-6. PubMed PMID: 18353084.

 

8: Moore JO, Wang Y, Stebbins WG, Gao D, Zhou X, Phelps R, Lebwohl M, Wei H. Photoprotective effect of isoflavone genistein on ultraviolet B-induced

pyrimidine dimer formation and PCNA expression in human reconstituted skin and its implications in dermatology and prevention of cutaneous carcinogenesis. Carcinogenesis. 2006 Aug;27(8):1627-35. Epub 2006 Mar 7. PubMed PMID: 16522663.

 

7: Kang S, Chung JH, Lee JH, Fisher GJ, Wan YS, Duell EA, Voorhees JJ. Topical N-acetyl cysteine and genistein prevent ultraviolet-light-induced signaling that  leads to photoaging in human skin in vivo. J Invest Dermatol. 2003 May;120(5):835-41. PubMed PMID: 12713590.

  

6: Pinnell SR. Cutaneous photodamage, oxidative stress, and topical antioxidant  protection. J Am Acad Dermatol. 2003 Jan;48(1):1-19; quiz 20-2. Review. PubMed PMID: 12522365.

 

5: Hermanns JF, Petit L, Piérard-Franchimont C, Paquet P, Piérard GE. Assessment  of topical hypopigmenting agents on solar lentigines of Asian women. Dermatology. 2002;204(4):281-6. PubMed PMID: 12077522.

 

4: Miyazaki K, Hanamizu T, Iizuka R, Chiba K. Genistein and daidzein stimulate hyaluronic acid production in transformed human keratinocyte culture and hairless mouse skin. Skin Pharmacol Appl Skin Physiol. 2002 May-Jun;15(3):175-83. PubMed PMID: 12077470.

 

3: Paine C, Sharlow E, Liebel F, Eisinger M, Shapiro S, Seiberg M. An alternative approach to depigmentation by soybean extracts via inhibition of the PAR-2 pathway. J Invest Dermatol. 2001 Apr;116(4):587-95. PubMed PMID: 11286627. 

 

2: Widyarini S, Spinks N, Reeve VE. Protective effect of isoflavone derivative

against photocarcinogenesis in a mouse model. Redox Rep. 2000;5(2-3):156-8. PubMed PMID: 10939302.

 

1: Hermanns JF, Petit L, Martalo O, Piérard-Franchimont C, Cauwenbergh G, Piérard GE. Unraveling the patterns of subclinical pheomelanin-enriched facial hyperpigmentation: effect of depigmenting agents. Dermatology. 2000;201(2):118-22. PubMed PMID: 11053913.  

DISCLAIMER:Any statements about products sold by BulkActives have not been evaluated by the FDA.  Products sold by BulkActives are not intended to be used as nutritional supplements. Products sold by BulkActives are not intended to diagnose, treat, cure, or prevent any disease.

About Soy and Isoflavones

 

The soybean (soya bean) is a species of legume native to East Asia, widely grown for its edible bean which has numerous uses.

 

The beans contain significant amounts of phytic acid, alpha-linolenic acid, and the isoflavones genistein and daidzein.

 

Isoflavones

 

Isoflavones comprise a class of organic compounds, often naturally occurring, related to the isoflavonoids.

 

 Many act as phytoestrogens in mammals. Some are termed antioxidants because of their ability to trap singlet oxygen.