Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients,  for DIY skin care and cosmetics, and homemade skin care products. 

BulkActives are DIY skin care suppliers of skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and standardized botanical extracts for diy skin care products and homemade cosmetics.

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Green Tea polyphenols EGCG for DIY skin care and cosmetics

Green Tea extract (standardized for 90% EGCG)

Green Tea polyphenols catechins ECGC

 

In our Green Tea extracts, EGCG makes up 70% or 90% of the total catechin content which seems to be the most powerful antioxidant among the catechins.

Green Tea and your skin

 

 

Green Tea (EGCG) and sun protection

Steven V. Joyal, MD,' The Sunscreen Paradox - Popular Misconceptions About Skin Cancer Prevention'. LE Magazine June 2006.

 

"EGCG, a prime component of green tea, provides broad-spectrum protection against UV light-induced DNA damage and immune system dysfunction of the skin. Topical green tea extract is exceptional in preventing the inflammation and oxidative stress associated with UV light-induced skin damage. As a result, scientists believe green tea may help prevent skin cancers that commonly result from exposure to the sun's radiation." Read more

 

 

Green Tea Polyphenols: Powerful Antioxidant Protection

Dave Tuttle, 'Scientifically Advanced Skin Care', LE Magazine January 2007.

 

"Numerous studies have shown that topical application of green tea confers broad-spectrum protection against photodamage, one of the leading causes of visibly aged skin. Polyphenols from green tea leaves have been found to protect against the adverse effects of overexposure to ultraviolet light" Read more

 

 

What green tea can and cannot do for your skin

Dr. G. Todorov, smartskincare.com

 

"Findings from a new study confirm that tea extracts applied to the skin promote the repair of damage from radiotherapy, and shed light on the mechanisms involved in the injury. The beneficial effects of the extracts are mostly from their ability to attenuate the body signals that trigger inflammation."

 

"Green tea appears to exert sun damage protection by quenching free radicals and reducing inflammation rather than by blocking UV rays. Therefore, green tea may synergistically enhance sun protection when used in addition to a sunscreen." Read more

Green Tea EGCG for topical use in skin care have both antioxidant and anti-inflammatory properties. Green tea EGCG has  shown exceptional protective, and restorative properties against the sun's damaging rays. EGCG may also treat and prevent keloid scars, and improve skin elasticity.

About Green Tea (EGCG)

 

Green tea extract comes from the natural dried leaves of the tea plant, Camellia sinensis. It has been used for thousands of years in China, both as a beverage and a herbal medicine. The active ingredients in green tea are a family of polyphenols/catechins and flavonols which possess potent antioxidant activity.

Product details

 

EGCG 90%

Assay: 93.92%% EGCG (epigallocatechin gallate)

Appearance: off-white to beige powder

Solubility: water, ethanol

Suggested percentage: 1% to 3%

 

Storage: Store in cool and dry place. Keep away from direct strong light and heat.

Country of origin: China

Several catechins are present in significant quantities, epicatechin (EC), epigallocatechin (EGC), epicatechin gallate (ECG) and epigallocatechin gallate (EGCG).

DISCLAIMER:Any statements about products sold by BulkActives have not been evaluated by the FDA.  Products sold by BulkActives are not intended to be used as nutritional supplements. Products sold by BulkActives are not intended to diagnose, treat, cure, or prevent any disease.

BulkActives: ingredients for DIY skin care and cosmetics
Green Tea EGCG (90%)





Green Tea and EGCG in skin care:

 

  • antioxidant
  • anti-inflammatory
  • sun damage protection
  • improve skin elasticity
  • scar care
  • increase skin thickness

 

 

 

 

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Green tea EGCG Research

 

Topically applied Green Tea EGCG may:

 

  • prevent or reduce UVA and UVB sun damage:  [37] [36] [35] [34] [30] [29] [28] [26] [25] [24] [23] [22] [20] [19] [17] [15] [14] [13] [12] [11] [10] [9] [8] [7] [6] [5] [4] [3] [2] [1]

 

  • improve skin elasticity: [21]

 

  • act as an anti- inflammatory: [36] [35] [6] [1]

 

  • treat and prevent keloids: [33] [27] [16]

 

  • stimulate hair growth: [31]

 

  • increase epidermal thickness: [18]

References  (full abstracts here)

 

37: Katiyar SK. Green tea prevents non-melanoma skin cancer by enhancing DNArepair. Arch Biochem Biophys. 2011 Apr 15;508(2):152-8. Epub 2010 Nov 19. Review.PubMed PMID: 21094124; PubMed Central PMCID: PMC3077767.

 

 

36: Domingo DS, Camouse MM, Hsia AH, Matsui M, Maes D, Ward NL, Cooper KD, Baron ED. Anti-angiogenic effects of epigallocatechin-3-gallate in human skin. Int J Clin Exp Pathol. 2010 Aug 5;3(7):705-9. PubMed PMID: 20830241; PubMed Central PMCID: PMC2933390.

 

 

35: Nichols JA, Katiyar SK. Skin photoprotection by natural polyphenols:

anti-inflammatory, antioxidant and DNA repair mechanisms. Arch Dermatol Res. 2010 Mar;302(2):71-83. Epub 2009 Nov 7. Review. PubMed PMID: 19898857; PubMed Central  PMCID: PMC2813915.

 

 

34: Camouse MM, Domingo DS, Swain FR, Conrad EP, Matsui MS, Maes D, Declercq L, Cooper KD, Stevens SR, Baron ED. Topical application of green and white tea extracts provides protection from solar-simulated ultraviolet light in human skin. Exp Dermatol. 2009 Jun;18(6):522-6. PubMed PMID: 19492999.

 

 

33: Park G, Yoon BS, Moon JH, Kim B, Jun EK, Oh S, Kim H, Song HJ, Noh JY, Oh C,

You S. Green tea polyphenol epigallocatechin-3-gallate suppresses collagen

production and proliferation in keloid fibroblasts via inhibition of the

STAT3-signaling pathway. J Invest Dermatol. 2008 Oct;128(10):2429-41. Epub 2008 May 8. PubMed PMID: 18463684.

 

 

32: Hsu S, Dickinson D, Borke J, Walsh DS, Wood J, Qin H, Winger J, Pearl H,

Schuster G, Bollag WB. Green tea polyphenol induces caspase 14 in epidermal

keratinocytes via MAPK pathways and reduces psoriasiform lesions in the flaky

skin mouse model. Exp Dermatol. 2007 Aug;16(8):678-84. PubMed PMID: 17620095.

 

 

31: Kwon OS, Han JH, Yoo HG, Chung JH, Cho KH, Eun HC, Kim KH. Human hair growth

enhancement in vitro by green tea epigallocatechin-3-gallate (EGCG).

Phytomedicine. 2007 Aug;14(7-8):551-5. Epub 2006 Nov 7. PubMed PMID: 17092697.

 

 

30: Sevin A, Ozta? P, Senen D, Han U, Karaman C, Tarimci N, Kartal M, Erdo?an B. Effects of polyphenols on skin damage due to ultraviolet A rays: an experimental  study on rats. J Eur Acad Dermatol Venereol. 2007 May;21(5):650-6. PubMed PMID:

17447979.

 

 

29: Katiyar S, Elmets CA, Katiyar SK. Green tea and skin cancer: photoimmunology,  angiogenesis and DNA repair. J Nutr Biochem. 2007 May;18(5):287-96. Epub 2006 Oct 17. Review. PubMed PMID: 17049833.

 

 

28: Yusuf N, Irby C, Katiyar SK, Elmets CA. Photoprotective effects of green tea

polyphenols. Photodermatol Photoimmunol Photomed. 2007 Feb;23(1):48-56. Review. PubMed PMID: 17254040.

 

 

27: Zhang Q, Kelly AP, Wang L, French SW, Tang X, Duong HS, Messadi DV, Le AD. Green tea extract and (-)-epigallocatechin-3-gallate inhibit mast cell-stimulated type I collagen expression in keloid fibroblasts via blocking PI-3K/AkT signaling pathways. J Invest Dermatol. 2006 Dec;126(12):2607-13. Epub 2006 Jul 13. PubMed PMID: 16841034.

 

 

26: Meeran SM, Mantena SK, Elmets CA, Katiyar SK. (-)-Epigallocatechin-3-gallate  prevents photocarcinogenesis in mice through interleukin-12-dependent DNA repair. Cancer Res. 2006 May 15;66(10):5512-20. PubMed PMID: 16707481.

 

 

25: Meeran SM, Mantena SK, Katiyar SK. Prevention of ultraviolet

radiation-induced immunosuppression by (-)-epigallocatechin-3-gallate in mice is

mediated through interleukin 12-dependent DNA repair. Clin Cancer Res. 2006 Apr 1;12(7 Pt 1):2272-80. PubMed PMID: 16609044.

 

 

24: Song XZ, Bi ZG, Xu AE. Green tea polyphenol epigallocatechin-3-gallate

inhibits the expression of nitric oxide synthase and generation of nitric oxide

induced by ultraviolet B in HaCaT cells. Chin Med J (Engl). 2006 Feb

20;119(4):282-7. PubMed PMID: 16537022.

 

 

23: Xia J, Song X, Bi Z, Chu W, Wan Y. UV-induced NF-kappaB activation and

expression of IL-6 is attenuated by (-)-epigallocatechin-3-gallate in cultured

human keratinocytes in vitro. Int J Mol Med. 2005 Nov;16(5):943-50. PubMed PMID:  16211268.

 

 

22: Mantena SK, Roy AM, Katiyar SK. Epigallocatechin-3-gallate inhibits

photocarcinogenesis through inhibition of angiogenic factors and activation of

CD8+ T cells in tumors. Photochem Photobiol. 2005 Sep-Oct;81(5):1174-9. PubMed PMID: 15938647.

 

 

21: Chiu AE, Chan JL, Kern DG, Kohler S, Rehmus WE, Kimball AB. Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin. Dermatol Surg. 2005 Jul;31(7 Pt 2):855-60; discussion 860. PubMed PMID: 16029678.

 

 

20: Nihal M, Ahmad N, Mukhtar H, Wood GS. Anti-proliferative and proapoptotic

effects of (-)-epigallocatechin-3-gallate on human melanoma: possible

implications for the chemoprevention of melanoma. Int J Cancer. 2005 Apr

20;114(4):513-21. PubMed PMID: 15609335.

 

 

19: Morley N, Clifford T, Salter L, Campbell S, Gould D, Curnow A. The green tea

polyphenol (-)-epigallocatechin gallate and green tea can protect human cellular

DNA from ultraviolet and visible radiation-induced damage. Photodermatol

Photoimmunol Photomed. 2005 Feb;21(1):15-22. PubMed PMID: 15634219.

 

 

18: Chung JH, Han JH, Hwang EJ, Seo JY, Cho KH, Kim KH, Youn JI, Eun HC. Dual

mechanisms of green tea extract (EGCG)-induced cell survival in human epidermal keratinocytes. FASEB J. 2003 Oct;17(13):1913-5. Epub 2003 Aug 1. PubMed PMID: 12897059.

 

 

17: Katiyar SK. Skin photoprotection by green tea: antioxidant and

immunomodulatory effects. Curr Drug Targets Immune Endocr Metabol Disord. 2003 Sep;3(3):234-42. Review. PubMed PMID: 12871030.

 

 

16: Hsu S, Bollag WB, Lewis J, Huang Q, Singh B, Sharawy M, Yamamoto T, Schuster  G. Green tea polyphenols induce differentiation and proliferation in epidermal keratinocytes. J Pharmacol Exp Ther. 2003 Jul;306(1):29-34. Epub 2003 Mar 27. PubMed PMID: 12663686.

 

 

15: Vayalil PK, Elmets CA, Katiyar SK. Treatment of green tea polyphenols in

hydrophilic cream prevents UVB-induced oxidation of lipids and proteins,

depletion of antioxidant enzymes and phosphorylation of MAPK proteins in SKH-1 hairless mouse skin. Carcinogenesis. 2003 May;24(5):927-36. PubMed PMID:

12771038.

 

 

14: Afaq F, Adhami VM, Ahmad N, Mukhtar H. Inhibition of ultraviolet B-mediated

activation of nuclear factor kappaB in normal human epidermal keratinocytes by

green tea Constituent (-)-epigallocatechin-3-gallate. Oncogene. 2003 Feb

20;22(7):1035-44. PubMed PMID: 12592390.

 

 

13: Tobi SE, Gilbert M, Paul N, McMillan TJ. The green tea polyphenol,

epigallocatechin-3-gallate, protects against the oxidative cellular and genotoxic

damage of UVA radiation. Int J Cancer. 2002 Dec 10;102(5):439-44. PubMed PMID: 12432544.

 

 

12: Katiyar SK, Bergamo BM, Vyalil PK, Elmets CA. Green tea polyphenols: DNA

photodamage and photoimmunology. J Photochem Photobiol B. 2001 Dec

31;65(2-3):109-14. Review. PubMed PMID: 11809367.

 

 

11: Katiyar SK, Afaq F, Azizuddin K, Mukhtar H. Inhibition of UVB-induced

oxidative stress-mediated phosphorylation of mitogen-activated protein kinase

signaling pathways in cultured human epidermal keratinocytes by green tea

polyphenol (-)-epigallocatechin-3-gallate. Toxicol Appl Pharmacol. 2001 Oct

15;176(2):110-7. PubMed PMID: 11601887.

 

 

10: Katiyar SK, Mukhtar H. Green tea polyphenol (-)-epigallocatechin-3-gallate

treatment to mouse skin prevents UVB-induced infiltration of leukocytes,

depletion of antigen-presenting cells, and oxidative stress. J Leukoc Biol. 2001

May;69(5):719-26. PubMed PMID: 11358979.

 

 

9: Elmets CA, Singh D, Tubesing K, Matsui M, Katiyar S, Mukhtar H. Cutaneous

photoprotection from ultraviolet injury by green tea polyphenols. J Am Acad

Dermatol. 2001 Mar;44(3):425-32. PubMed PMID: 11209110.

 

 

8: Katiyar SK, Afaq F, Perez A, Mukhtar H. Green tea polyphenol

(-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet

radiation-induced oxidative stress. Carcinogenesis. 2001 Feb;22(2):287-94. PubMed PMID: 11181450.

 

 

7: Kim J, Hwang JS, Cho YK, Han Y, Jeon YJ, Yang KH. Protective effects of

(-)-epigallocatechin-3-gallate on UVA- and UVB-induced skin damage. Skin

Pharmacol Appl Skin Physiol. 2001 Jan-Feb;14(1):11-9. PubMed PMID: 11174086.

 

 

6: Katiyar SK, Ahmad N, Mukhtar H. Green tea and skin. Arch Dermatol. 2000

Aug;136(8):989-94. Review. PubMed PMID: 10926734.

 

 

5: Zhao JF, Zhang YJ, Jin XH, Athar M, Santella RM, Bickers DR, Wang ZY. Green

tea protects against psoralen plus ultraviolet A-induced photochemical damage to  skin. J Invest Dermatol. 1999 Dec;113(6):1070-5. PubMed PMID: 10594754.

 

 

4: Katiyar SK, Challa A, McCormick TS, Cooper KD, Mukhtar H. Prevention of

UVB-induced immunosuppression in mice by the green tea polyphenol

(-)-epigallocatechin-3-gallate may be associated with alterations in IL-10 and

IL-12 production. Carcinogenesis. 1999 Nov;20(11):2117-24. PubMed PMID: 10545414.

 

 

3: Katiyar SK, Matsui MS, Elmets CA, Mukhtar H. Polyphenolic antioxidant

(-)-epigallocatechin-3-gallate from green tea reduces UVB-induced inflammatory

responses and infiltration of leukocytes in human skin. Photochem Photobiol. 1999 Feb;69(2):148-53. Review. PubMed PMID: 10048310.

 

 

2: Barthelman M, Bair WB 3rd, Stickland KK, Chen W, Timmermann BN, Valcic S,

Dong Z, Bowden GT. (-)-Epigallocatechin-3-gallate inhibition of ultraviolet

B-induced AP-1 activity. Carcinogenesis. 1998 Dec;19(12):2201-4. PubMed PMID: 9886579.

 

 

1: Katiyar SK, Elmets CA, Agarwal R, Mukhtar H. Protection against ultraviolet-B

radiation-induced local and systemic suppression of contact hypersensitivity and

edema responses in C3H/HeN mice by green tea polyphenols. Photochem Photobiol. 1995 Nov;62(5):855-61. PubMed PMID: 8570723.