Product details

 

Source: biotechnology (bacterial fermentation)

Grade: cosmetic grade

CAS#:9004-61-9
Molecular weight: 5000 daltons ( 5.0 x 10³ daltons )
Solubility: water (this pure powder dissolves very well in water, some mixing may be required.)
suggested percentage: 0.5 to 1%

Storage: cool, dry place. Do not freeze. Keep away from light and moisture!
Country of origin: China

About Hyaluronic acid and topical skin care

 

When HA is applied to the skin, macromolecular HA can form an air permeable thin layer and keep the skin smooth and moist, and protect the skin from bacteria, dust, and ultraviolet ray.

 

With low molecular HA penetrating into corium, it will slightly enlarge blood capillaries, speed circulation of blood, improve intermediary metabolism and nourishment absorbing ability of skin, thus eliminating wrinkles, increasing skin's elasticity and delaying its aging. HA can further hyperplasia of epidermis cell, clean oxygen free radical, prevent and rehabilitate breach of skin.

 

Its aqueous solution has very high viscosity which can make water become thicker. Creams made by means of emulsifying HA with oil are fine and homogeneous with stable emulsifiction"

 

Also read: The Wonders of Hyaluronic Acid: Nature's First Cosmeceutical by Dr. Dennis Gross

 

Manufacturing company: Our supplier is a  UK registered company, with their manufacturing facilities in China. They develop and market innovative ingredients for the Nutritional Market.

 

Manufacturing low weight NaH:Low molecular weight Hyaluronic acid requires an extra production step compared to normal Hyaluronic acid production. Manufacturers use a chemical method to cut large molecular weight Hyaluronic Acid into low molecular weight.

 

Our normal product is naturally fermented, no animal products are used.

Low molecular weight hyaluronic acid research

 

Low molecular weight hyaluronic acid prevents oxygen free radical damage to granulation tissue during wound healing.

"Hyaluronic acid protects granulation tissue from oxygen free radical damage and stimulates wound healing, but its molecular weight prevents it from permeating the epidermal barrier A low molecular weight hyaluronic acid preparation is able to permeate the skin, but it is unknown whether or not it retains the scavenging effects of oxygen free radicals in granulation tissue. Our experiments were conducted in rats with excisional or incisional wounds. Wound contraction over 11 days and breaking strength on the fifth day were measured. Oxygen free radical production was induced by intraperitoneal administration of two different xenobiotics: phenazine methosulfate and zymosan. The wounds were treated topically with low molecular weight hyaluronic acid (0.2%) cream or placebo. In the incisional wound group, the effects of superoxide dismutase were also determined. Absolute controls received wounds and placebo but no xenobiotics. Wound healing was significantly slower in the xenobiotic group than in the control groups. These effects were strongly reduced by topical administration of low molecular weight hyaluronic acid (0.2%) cream and in incisional wounds by topically injected superoxide dismutase. Low molecular weight hyaluronic acid is effective as the native compound against oxygen free radicals. Its pharmacological effects through transdermal administration should be tested in appropriate models."

Ultra Low Molecular Weight Hyaluronic Acid (ulmw NaH) is a powerful moisturizing ingredient that also has humectants properties. You can find it used in many skin care recipes. In its ULMW form, NaH also provides healing properties and can be used for wound care.