Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
Reviews
I am following the moisturizing cream + Zinc dispersion recipe and I am extremely satisfied. I do allow for a little time for it to absorb in & then I dab off anything that I feel looks a little white - but that's because I initially use a fairly thick coating on myself. I use a bit of foundation at times on top and there are no issues as far as weird colors or texture issues. I am so grateful for this entire website as a one-stop-shop for such effective skin care products, and now we can.. ...»
Peggy
Excellent quality, very fine texture and disperses easily when used correctly. Arrived in just seven days to London, England and with a reasonable postage fee. Very pleased... ...»
D N Bay
The best, most potent and most stable form of Vitamin C. Makes quite a difference to the appearance of mature, photo-damaged skin - don't expect results over night but with consistent use your skin will look more even and radiant!.. ...»
Judy
Very good product. It performed exactly how I expected. .. ...»
Ryan
This ingredient has done more for my skin than anything else I've ever used. I put it into a spray facial toner and use it morning and night. I noticed the effects immediately, they were that dramatic. I will use this forever, no question... ...»
Marie
Love the fine powder ascorbic acid. I use it in a recipe for skin care along with hyaluronic acid. I'm 65 years old and absolutely no one believes it 'cause I've been doing this for years... ...»
Kathy
Purchased this some time ago from BulkActives and here to buy some more! Great stuff!!!!.. ...»
Kathy
I've been using Bulkactives green tea EGCG for four years. No complaints, it blends nicely my DIY anti-aging cream. I can feel a bit of toning and definitely notice the anti-inflammatory effects on my skin. Two observations that keep the rating 4 stars instead of 5: (1) A package of green tea contains significantly less weight/volume than the package of grape seed extract that I order from bulkactives. The two are combined in equal amounts in the anti-aging cream, so I find myself running o.. ...»
Theresa Andrews
Awesome Product and thanks for such a nice Product description .. ...»
Stephen
I ordered the 50 gm after being very pleased with the smaller size. Although it's pricey the quality is outstanding. This is the safest way to add Vit C to your formulations as it's not nearly as fussy as the powder. I've made both serums and creams with this product and have been very pleased with the outcomes! Highly recommend!.. ...»
Annabelle
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sun damage protection

Sun damage protection and prevention in skin care

Since the beginning of times the Sun has been the life giver and care taker of the planet and all living beings, including humans. However, in the in the recent history sun has became an unsuspected enemy due not necessarily to its own activity but rather to the major changes in human lifestyle, pollution, ozone depletion and other environmental phenomena. The last century especially is characterized by an accelerated industrialization process that not only created change in our biosphere but also provided a fast progress for the human race allowing. Humans work and live in controlled environments, usually in indoor ventilated premises, eat hyper-processed food and use a lot of chemicals on a daily basis. Thus, humans have become more sensitive to sun exposure and implicitly more susceptible to sun damage.

Sun damage, better said UV radiation damage is the totality of harmful processes caused by sun exposure in the human living tissues, especially skin – the outer barrier of our bodies. The UVR (ultraviolet radiation) with its subtype spectrums UVA and UVB is considered to be the most harmful and damaging to living beings. Prolonged and unprotected UVR exposure is the leading cause several skin conditions such as: hyper and hypo pigmentation, dryness and scaling, photoaging and last, but unfortunately not least non-malignant and malignant skin tumors.
Both UVA (wavelength 320-400nm) and UVB (wavelength 280-320nm) are recognized as carcinogenetic factors though their actions are different. There are multiple complex mechanisms and the effects are complex numerous:

DNA damage is mainly caused by UVB radiation which directly damages the genetic information (DNA – dezoxiribonucleic acid) within skin cells, causing specific DNA lesions called photoproducts. If not repaired properly, these lesions can lead to the development of skin cancer. Because  DNA encodes the genetic information which provides instructions for the form, structure and function of living cells and how they behave when it gets damaged there are regulating mechanisms that either correct and repair the double helix or it suppress it by apoptosis (cell death). However, sometimes, under UVR influence the DNA damaged remains unfixed or is incorrectly fixed and it remains permanent. Such a mutation can proliferate and migrate thus being a serious threat for initiation and progress of skin cancer.

Oxidative damage, mainly caused by UVA, is an unwanted effect of an unbalance oxidation process. Oxidation is a chemical reaction between oxygen (O2) and other molecules that is constant and natural in the human body, being the primarily energy source in the mitochondria. Reactive oxygen species (ROS) is an aggressive (do to their ion state) category of reactive oxidants that is naturally produced as a by-product of oxidation in very low levels that are needed in certain metabolic reaction. However ROS levels are considerably increased by UVR exposure and become toxic to the cell that encloses them.

Due to its superior wavelength UVA is more aggressive because it penetrates both epidermis and dermis and in dermis it affects the three-dimensional extracellular matrix causing the loss of elasticity and thus a catalyst in skin premature aging.

 While UVB is a tumor initiator mainly trough DNA mutation, UVA is a tumor accelerator by affecting the mitochondrial metabolism and exaggerating the ROS levels. [1] [2] [3]
For years scientific efforts were directed to chemically combat all the UVR exposure efforts, especially trough sun damage protection and sun damage repair by using various synthetic combinations that proved to have limited effects. Only relatively recent the important field of sun damage prevention and repair started to focus on a source that was available all along and historically known for ages: botanical actives.

While fairer, sensitive and young skin is more sensitive to sun exposure all the skin types and genetic variations need protection as it represent a constant barrier between the inner cells and the outer, sometimes aggressive environment. Sun damage protection and prevention is classically done by topical sunscreen but late studies also shown that usage of locally applied antioxidants is also a great adjuvant.

Some of the botanical actives have been known for antioxidant properties and sun damage protection even from antiquity, some are only recently discovered but all of them deserve attention since they have little to none side effects and overdosing is virtually impossible. This articles presents the most important natural active ingredients used in the topical protection against sun damage.
 
Ascorbic Acid (AA,Vitamin C) is perhaps the most popular natural antioxidant. Its sun damage protection is maximized in combination with Vitamin E, the two actives being symbiotic. Basically Vitamin C scavenges reactive oxygen species (ROS) including oxidized alpha-tocopherol participating in increasing the vitamin E levels in the skin and implicitly increase the skin protection [4] [5].
Ascorbyl Glucoside (AA-2G), is the reaction product between Vitamin C and Glucose. As an antioxidant, AA-2G was found to perform similarly or even better than ascorbic acid, for example, in protecting skin cells from ultraviolet radiation [6], [7]. It was also observed to protect cells against damage from high-energy radiation, similar to that used in radiotherapy.
Ascorbyl Tetraisopalmitate is a derivate from Vitamin C and isopalmitic acid, a more recent discovery, is even superior to Ascorbic Acid alone due to higher stability and deliverability. It prevents sun damage both trough fighting DNA damage [8] and ROS scavenging [9] reducing or even eliminating permanent effects.

 Baobab Oil, preferably organic, a natural extract rich in fatty acids has proved to help in preventing and treating sunburn and photo-aging, chronic skin damage due to excessive sun exposure [10].
Centella Asiatica (Gotu Kola) extract is obtained from a tropical plant traditionally and extensively used in Indian medicine. This botanical active showed relevant results both in sun damage protection and repair when used topically [11] [12].

Ethyl Ascorbic Acid is a more stable variation of Vitamin C. Its advantage is being able to manifest a higher rate of antioxidant activity due to its greater stability at skin level.Like vitamin C, ethyl ascorbic acid exhibits a protective effect against UV radiation and due to this properties it is used in several cosmetics products as a skin whitener or sunscreen ingredient [13][14].
Natural Ferulic Acid, is an organic acid found in several plants, especially cereals as rice and corn. It is very effective in UV protection, especially in combinations with Vitamin C and E. The combination prevents DNA damage and is excellent in ROS scavenging. Even standalone, topical applied ferulic acid generates dramatically reduction of sun damage in clinical trials even superior to Vitamin C and E combination. [15][16].

Gamma-oryzanol is a natural active ingredient obtained from rice bran, a bundle of sterols build on a ferulic acid backbone. Due to its antioxidant properties it has the ability to prevent sun damage and photoaging by scavenging ROS and inhibiting sun-related DNA damage [17].

Ginkgo Biloba is another traditional natural active ingredient, renowned for its potency and versatility. In vitro and in vivo studies showed that the ginkgo biloba flavonoids protect the skin from UV generated free radicals and additionally they counter-attack by increasing the levels of ROS scavenging enzymes. [18] [19].

Glucosamine a natural precursor of the hyaluronic acid is a treasure for topical skin care in general with proved sun damage protection properties. N-acetyl glucosamine increases activity of antioxidant enzymes reducing the amount of harmful free radicals produced after UV exposure, preventing photoaging and sun dmage. It is also known to scavenge free radicals and inhibit MMP that degrade collagen after UV damage [20].

Grape seed oil contains polyphenols responsible for reducing prolonged sun exposure effects and preventing the premature aging of the skin due to UV generated free radicals [21].
Green tea extract has a potent antioxidant called EGCG in its composition. Due to its activity the green tea extract protects the skin from reddening, DNA damage and even cell death following UV exposure. The strong antioxidants found in the extract also neutralize free radicals. This helps to prevent the whole spectrum of UVR damage, and most importantly, skin cancer [22] [23].
Hesperidin methyl is a stable version of  hesperidin – an active usually extracted from citrus plants and a natural flavonoid. Its action when topically applied reduces sun damage effects and also prevents damage proliferation trough DNA mutation [24].

Phytosterols are plant produced sterols unavailable in the human body. Spinosterol and Fucosterol are the most effective in inhibiting ROS production and UV mutations and enhancing antioxidant enzyme levels thus offering a multilevel protection against sun damage [25][26].

 Pine bark extract contains active molecules called proanthocyanidins that have very strong antioxidant properties and they are also known to reduce erythema caused by sun exposure. Topically applied, the extract not only reduces UVR caused cutaneous irritation but also helps regulate the capillary growth and implicitly faster healing of the damage [27].

Pomegranate through its main component – ellagic acid -  and Pomegranate seeds oil – very rich in fatty acids are efficient botanical actives used in topical skin protection against sun damage. Studies have shown that ellagic acid reduces UV-induced cell death, inflammatory processes, and even freezes cells in an non-dividing stage, giving them more time to repair their DNA. The seeds extract also proved to be effective in reducing fibroblasts apoptosis and decreasing ROS levels after UVR exposure [28].
 
Quercetin is a natural flavonoid produced by several plants, especially onion and related family. It is a very effective free radicals scavenger acting on two levels – directly or by binding iron – a vital metal in the ROS metabolism. Topically using quercetin emulsions helps and enhances the natural defenses against free radicals by restoring the anti-ROS enzymes levels [29].
Safflower seed oil is popular for being the plant oil rich in fatty acids with the highest content of linoleic acid. It has multiple topical treatment usages, one of them being the reduction of hyperpigmentation in UVR exposure, and the related damage [30].
 
Salicylic Acid (Beta Hydroxy Acid)  is another effective protector against sun damage. Topically applied salicylic acid before prolonged sun exposure proved to reduce redness and inflammation [31].

Sylimarin has potent antioxidant activity and recognized potential as an antiphotodamage and anticarcinogenic agent, the extract of Silybum marianum is suitable for inclusion in topical skin care products and sunscreen as active ingredient [32].

Soy isoflavones are phytoestrogens that showed efficiency in inhibiting UV-stimulated tyrosine kinases responsible for initiation of inflammation therefore having the capability to protect the integrity of the dermal matrix and to prevent UV-induced damage to the skin [33].

Squalane olive oil is a versatile active with numerous cosmetic uses. Its most important function is as an antioxidant and due to the fact that squalane is also found in the normal occurring skin sebum the protection against UVR damage is very natural and well tolerated [34].

Natural Vitamin E in its most stable and efficient forms tocopherols and tocotrienols is an omnipresent ingredient in UVR protection treatments. Both its forms proved to be efficient in preventing DNA damage, ROS scavenging, reducing cutaneous effects [35].

Wheat germ oil is known to be rich in vitamins A, D and E. The vitamin E in its component is proved to inhibit collagen degradation and protects against UVR inflammation and sunburn [36].
Yeast beta glucan is a natural polymer occurring especially in fungi and algae. Its structure makes it ideal for topical treatment meant for human skin. In sun damage prevention relevant results were observed especially in the reduction of UVB induced skin damage [37].

Zinc oxide, though not a botanical active per se, is renowned for its sun damage protection properties. Due to its ability to absorb UVA and UVB radiation ZnO is widely used in physical sunscreens as a protection against UV radiation. Furthermore, zinc oxide based sunscreen offers the best UVA and UVB coverage and protection according to FDA [38] [39].
 

 References

[1]  World Health Organization, International Agency for Research on Cancer "Do sunscreens prevent skin cancer" Press release No. 132, June 5, 2000
[2]  World Health Organization, International Agency for Research on Cancer  Humans, Volume 55, November 1997
[3] S.R. Pinell, “Cutaneous photodamage, oxidative stress, and topical antioxidant protection”, J Am Acad Dermatol, pp:3-19,2003
[4] W. C. Quevedo, T. J. Holstein, J. Dyckman, and C. J. McDonald, “The responses of the human epidermal melanocyte system to chronic erythemal doses of UVR in skin protected by topical applications of a combination of vitamins C and E,” Pigment Cell Res. Spons. Eur. Soc. Pigment Cell Res. Int. Pigment Cell Soc., vol. 13, no. 3, pp. 190–192, Jun. 2000.
[5]  F. Dreher, B. Gabard, D. A. Schwindt, and H. I. Maibach, “Topical melatonin in combination with vitamins E and C protects skin from ultraviolet-induced erythema: a human study in vivo,” Br. J. Dermatol., vol. 139, no. 2, pp. 332–339, Aug. 1998.
[6] E. Miyai, M. Yanagida, J. Akiyama, and I. Yamamoto, “Ascorbic acid 2-O-alpha-glucoside-induced redox modulation in human keratinocyte cell line, SCC: mechanisms of photoprotective effect against ultraviolet light B,” Biol. Pharm. Bull., vol. 20, no. 6, pp. 632–636, Jun. 1997.
[7] E. Miyai, M. Yanagida, J. Akiyama, and I. Yamamoto, “Ascorbic acid 2-O-alpha-glucoside, a stable form of ascorbic acid, rescues human keratinocyte cell line, SCC, from cytotoxicity of ultraviolet light B,” Biol. Pharm. Bull., vol. 19, no. 7, pp. 984–987, Jul. 1996.
[8] L. Xiao, K. Kaneyasu, Y. Saitoh, Y. Terashima, Y. Kowata, and N. Miwa, “Cytoprotective effects of the lipoidic-liquiform pro-vitamin C tetra-isopalmitoyl-ascorbate (VC-IP) against ultraviolet-A ray-induced injuries in human skin cells together with collagen retention, MMP inhibition and p53 gene repression,” J. Cell. Biochem., vol. 106, no. 4, pp. 589–598, Mar. 2009.
[9]  R.E. Fitzpatrick, E.F. Rostan. “Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage,” Dermatol Surg. 2002 Mar;28(3):231-6. PubMed PMID: 11896774.
[10]  P. Engels, “Cosmetic Preparations with an Additive from the Baobab Tree,” United States Patent Application, pp. 1-28, December 2009.
[11]  G. Maramaldi, S. Togni, F. Franceschi, and E. Lati, “Anti-inflammaging and antiglycation activity of a novel botanical ingredient from African biodiversity (CentevitaTM),” Clin. Cosmet. Investig. Dermatol., vol. 7, pp. 1–9, 2013.
[12] E. Jung, J.-A. Lee, S. Shin, K.-B. Roh, J.-H. Kim, and D. Park, “Madecassoside inhibits melanin synthesis by blocking ultraviolet-induced inflammation,” Mol. Basel Switz., vol. 18, no. 12, pp. 15724–15736, 2013.
[13] K. Maeda, Inoue, Y., Nishikawa, H., Miki, S., Urushibata, O., Miki, T., and Hatao, M., “Involvement of melanin monomers in the skin persistent UVA-pigmentation and effectiveness of vitamin C ethyl on UVA-pigmentation,” Nippon Koshohin Kagakkaishi, vol. 27, no. 4, pp. 257–268, 2003.
[14] H.Toshie, I. Hakano, “External composition for skin containing 3-O-ethylascorbic acid,” 2014-009172.
[15]  A. Saija, A. Tomaino, D. Trombetta, A. De Pasquale, N. Uccella, T. Barbuzzi, D. Paolino, and F. Bonina, “In vitro and in vivo evaluation of caffeic and ferulic acids as topical photoprotective agents,” Int. J. Pharm., vol. 199, no. 1, pp. 39–47, Apr. 2000.
[16]  F.-H. Lin, J.-Y. Lin, R. D. Gupta, J. A. Tournas, J. A. Burch, M. A. Selim, N. A. Monteiro-Riviere, J. M. Grichnik, J. Zielinski, and S. R. Pinnell, “Ferulic Acid Stabilizes a Solution of Vitamins C and E and Doubles its Photoprotection of Skin,” J. Invest. Dermatol., vol. 125, no. 4, pp. 826–832, Oct. 2005.
[17]  C. Punvittayagul, K. Sringarm, C. Chaiyasut, and R. Wongpoomchai, “Mutagenicity and antimutagenicity of hydrophilic and lipophilic extracts of Thai northern purple rice,” Asian Pac. J. Cancer Prev. APJCP, vol. 15, no. 21, pp. 9517–9522, 2014.
[18]   J. Hibatallah, C. Carduner, and M. C. Poelman, “In-vivo and in-vitro assessment of the free-radical-scavenger activity of Ginkgo flavone glycosides at high concentration,” J. Pharm. Pharmacol., vol. 51, no. 12, pp. 1435–1440, Dec. 1999.
[19]  A. Aricioglu, M. Bozkurt, B. Balabanli, M. Kilinç, N. K. Nazaroglu, and N. Türközkan, “Changes in zinc levels and superoxide dismutase activities in the skin of acute, ultraviolet-B-irradiated mice after treatment with ginkgo biloba extract,” Biol. Trace Elem.
[20] Y.P. Hwang, H.G. Kim, E.H. Han, J.H. Choi, B.H. Park, K.H. Jung, Y.C. Shin, and H.G. Jeong, “N- Acetylglucosamine suppress collagenases activation in ultraviolet B-irradiated human dermal  fibroblasts: Involvement of calcium ions and mitogen-activated protein kinases,” Journal of Dermatological Science, vol. 63, pp. 93–103, 2011
[21] J. Shi, J. Yu, J.E. Pohorly, and Y. Kakuda, “Polyphenolics in Grape Seeds—Biochemistry and Functionality,” Journal of Medicinal Food, vol. 6, issue 4, pp. 291-299, 2003.
[22] C. A. Elmets, D. Singh, K. Tubesing, M. Matsui, S. Katiyar, and H. Mukhtar, “Cutaneous photoprotection from ultraviolet injury by green tea polyphenols,” J. Am. Acad. Dermatol., vol. 44, no. 3, pp. 425–432, Mar. 2001.
[23] S.-Y. Kim, D.-S. Kim, S.-B. Kwon, E.-S. Park, C.-H. Huh, S.-W. Youn, S.-W. Kim, and K.-C. Park, “Protective effects of EGCG on UVB-induced damage in living skin equivalents,” Arch. Pharm. Res., vol. 28, no. 7, pp. 784–790, Jul. 2005.
[24] J. T. Bae, H. J. Ko, G. B. Kim, H. B. Pyo, and G. S. Lee, “Protective effects of fermented Citrus unshiu peel extract against ultraviolet-A-induced photoageing in human dermal fibrobolasts,” Phytother. Res. PTR, vol. 26, no. 12, pp. 1851–1856, Dec. 2012.
[25] T. H. Lee, S. M. Lee, D.-Y. Lee, Y. Son, D. K. Chung, N.-I. Baek, and J. Kim, “A glycosidic spinasterol from Koreana stewartia promotes procollagen production and inhibits matrix metalloproteinase-1 expression in UVB-irradiated human dermal fibroblasts,” Biol. Pharm. Bull., vol. 34, no. 5, pp. 768–773, 2011.
[26] M.-S. Kim, G.-H. Oh, M.-J. Kim, and J.-K. Hwang, “Fucosterol inhibits matrix metalloproteinase expression and promotes type-1 procollagen production in UVB-induced HaCaT cells,” Photochem. Photobiol., vol. 89, no. 4, pp. 911–918, Aug. 2013.
[27] C. Saliou, G. Rimbach, H. Moini, L. McLaughlin, S. Hosseini, J. Lee, R. R. Watson, and L. Packer, “Solar ultraviolet-induced erythema in human skin and nuclear factor-kappa-B-dependent gene expression in keratinocytes are modulated by a French maritime pine bark extract,” Free Radic. Biol. Med., vol. 30, no. 2, pp. 154–160, Jan. 2001.
[28] L. A. Pacheco-Palencia, G. Noratto, L. Hingorani, S. T. Talcott, and S. U. Mertens-Talcott, “Protective effects of standardized pomegranate (Punica granatum L.) polyphenolic extract in ultraviolet-irradiated human skin fibroblasts,” J. Agric. Food Chem., vol. 56, no. 18, pp. 8434–8441, Sep. 2008
[29]  F. T. M. C. Vicentini, T. He, Y. Shao, M. J. V. Fonseca, W. A. Verri, G. J. Fisher, and Y. Xu, “Quercetin inhibits UV irradiation-induced inflammatory cytokine production in primary human keratinocytes by suppressing NF-κB pathway,” J. Dermatol. Sci., vol. 61, no. 3, pp. 162–168, Mar. 2011.
[30] J.S. Roh, J.Y. Han, J.H. Kim, and J.K. Hwang, “Inhibitory Effects of Active Compounds Isolated from Safflower [Carthamus tinctorius L.] Seeds for Melanogenesis,” Biol. Pharm. Bull., vol. 27, no. 12, pp. 1976-1978, 2004.
[31] A. Kornhauser, S.G. Coelho, and V.G. Hearing, “Applications of hydroxy acids: classification, mechanisms, and photoactivity,” Clin Cosmet Investig Dermatol., vol. 3, pp. 135-142, 2010.
[32] Alena Svobodova, Jitka Psotova, Daniela Walterova, “Natural phenolics in the prevention of UV-induced skin damage. A Review”,  Biomed. Papers 147(2), 137–145, 2003
[33] C.C. Miller, P. Hale, A,P, Pentland, “Ultraviolet B injury increases prostaglandin synthesis through a tyrosine kinase-dependent pathway. Evidence for UVB-induced epidermal growth factor receptor activation,”, Journal of Biological Chemistry. 1994;269[5]:3529-33.
[34] Y. Kohno, Y. Egawa, S. Itoh, S. Nagaoka, M. Takahashi, and K. Mukai, “Kinetic study of quenching reaction of singlet oxygen and scavenging reaction of free radical by squalene in n-butanol,” Biochimica et Biophysica Acta, vol. 1256, pp. 52-56, 1995.
[35] M. McVean and D.C. Liebler, “Prevention of DNA photodamage by vitamin E compounds and sunscreens: roles of ultraviolet absorbance and cellular uptake,” Mol Carcinog., vol. 24, issue 3, pp. 169-176, March 1999.
[36] J.J. Thiele, S.N. Hsieh, and S. Ekanayake-Mudiyanselage, “Vitamin E: Critical Review of Its Current Use in Cosmetic and Clinical Dermatology,” Dermatol Surg,vol. 31, pp. 805-813, 2005.
[37]    B. Du, Z. Bian, and B. Xu, “Skin Health Promotion Effects of Natural Beta-Glucan Derived from Cereals and Microorganisms: A Review,” Phytother. Res., vol. 28, no. 2, pp. 159–166, Feb. 2014.
[38] B.D. More, “Physical sunscreens: On the comeback trail”, Indian Journal of Dermatology, Venerology and Leprology, 73, pp 80-85, 2007 
[39] United States Environmental Protection Agency (EPA), Air and Radiation,  EPA 430-F-06-013, 2006 
 
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Ascorbic Acid -L  (ultra fine powder)

L-ascorbic acid (vitamin C) is an essential nutrient which has many cosmetic benefits. It is a remarkable antioxidant and can scavenge reactive oxygen species and other free radicals, protecting the skin from oxidative stress. It can stimulate collagen synthesis by promoting cross-linking and stabilizing collagen molecules, upregulating collagen genes, increasing the transcription of the tissue inhibitor of matrix metalloproteinase 1, and inducing fibroblast proliferation. It reduces pigmentation by suppressing tyrosinase, which is important for melanin production. It is an anti-inflammatory agent and can be used to treat inflammatory skin disease such as erythema. Together, L-ascorbic acid provides powerful anti-aging properties and has been shown to reduce wrinkles, improve elasticity, and protect against sun damage. Stability and absorption of L-ascorbic acid is a concern. While the anhydrous L-ascorbic acid might be the most stable form, adding vitamin E not only helps stabilizing L-ascorbic acid, but the two have synergistic effects on anti-aging.  Used in: philosopy's turbo booster c powder and SkinCeuticals.

Key benefts of L-ascorbic acid in skin care:

  • Anti-inflammatory [31]
  • Antioxidant [4] [5] [6] [7] [8]
  • Increase skin elasticity [26]
  • Lightening and brightening [4] [22] [28] [29] [30]
  • Matrix metalloproteinases (MMP) inhibitors [19]
  • Moisturizing and hydration [21]
  • Reduce fine lines and wrinkles [7] [21] [22] [25] [26]
  • Ttimulate collagen production [5] [13] [14] [15] [16] [17] [18] [19] [20] [21] [22] [23] [24]
  • Sun damage protection [9] [11]
  • Sun damage repair [6] [22] [26]
  • Teat hyperpigmentation [4] [9] [22] [25] [28] [29] [30]
  • Wrinkle relaxers [22]
$6.50
Based on 4 reviews.
Ascorbyl Glucoside (Ascorbic Acid 2- Glucoside)
Ascorbyl glucoside (AA-2G) is a vitamin derivative, produced biologically by the reaction between glucose and vitamin C. This addition confers greater stability, compared to relatively unstable pure ascorbic acid, thus allowing for wide usage in pharmacy and cosmetics. AA-2G retains the antioxidant properties of the unmodified vitamin, therefore it is used to prevent radiation damage, cell senescence and skin darkening. It also promotes collagen synthesis, as well as cell proliferation – these mechanisms help improve the appearance of the skin and reduce wrinkles. Furthermore, since AA-2G does not release ascorbic acid instantly, all the listed positive effects are sustained longer and the possibility of adverse effects is reduced, compared to using pure ascorbic acid. All these qualities make AA-2G the most attractive vitamin C derivative for cosmetic use.

Key benefits of Ascorbyl glucoside (AA-2G)  in skin care:

  • Antioxidant [10] [16]
  • Lightening and brightening [14]
  • Treat hyperpigmentation [14]
  • Sun damage repair [10] [16]
  • Sun dammage protection [7] [9]
  • Stimulate collagen production [3] [13]
  • Reduce fine lines and wrinkles [12]
$25.00
Ascorbyl Tetraisopalmitate (Tetrahexyldecyl Ascorbate)

Ascorbyl tetraisopalmitate (Tetrahexyldecyl Ascorbate) is a molecule derived from vitamin C and isopalmitic acid. Pure vitamin C has several drawbacks for cosmeceutical use, most important of which is the low stability. Chemically modified vitamin molecules are more stable, and pure vitamin is released from the derivatives inside the body. Therefore, the effects of Tetrahexyldecyl Ascorbate are similar to those of vitamin C, most importantly it is able to act as an antioxidant. Ascorbyl tetraisopalmitate reduces the production of oxidizing agents, which contribute to cell damage after exposure to UV or chemical hazards. This effect is even stronger in the modified molecule than in pure vitamin C. Additionally, Tetrahexyldecyl Ascorbate protects against DNA damage and skin darkening caused by UV exposure. Finally, skin visual appearance is also improved by Ascorbyl tetraisopalmitate, as it promotes collagen synthesis and acts as a hydrating agent in reducing skin roughness.

Key benefits of Ascorbyl tetraisopalmitate in skin care:

  • Sun damage protection [1] [2] [7]
  • Sun damage repair [2]
  • Antioxidant [1] [6]
  • Moisturizing and hydration [5]
  • Stimulate collagen production [2]
  • Lightening & brightening [1]
  • treat hyperpigmentation [1]
$28.60
Based on 3 reviews.
Baobab Oil Organic
Baobab seed oil is a highly moisturizing and skin smoothing therapeutic. It is rich in fatty acids, particularly linoleic [omega-6] and oleic [omega-9] acids. These fatty acids help restore the barrier function of skin, especially thin, aged skin. Baobab seed oil also contains healthy vitamins A, D, E, and F that rejuvenate skin. In addition to moisturizing, baobab seed oil aids in wound healing, collagen production, sun damage protection and repair, and can prevent wrinkles. It has anti-microbial, anti-inflammatory, and anti-oxidant properties. Overall, baobab seed oil can improve the softness and strength of all skin types, even irritated skin.

Key benefits of Baobab oil in skin care:

  • Moisturizing and hydration  [5] [9] [10] [11]
  • Restore barrier function [5] [6] [7] [9] [13]
  • Anti-inflammatory [5] [8] [9] [11]
  • Wound healing support [5] [9] [11]
  • Anti-bacterial [5] [6] [7]
  • Anti-oxidant [5] [9]
  • Increase skin elasticity [5] [9]
  • Anti-acne [5]
  • Sun damage protection [4]
  • Sun damage repair [5]
  • Oil/sebum control [11]
  • Stimulate collagen production [4]
BulkActives' oils are cold pressed, without the use of solvents or chemicals.

 
$27.20
Centella asiatica (Gotu Kola)

Centella asiatica is a tropical plant that has been used extensively in Indian medicine. It has diverse applications for skin cosmetics: firstly, it is effective in wound care, as it promotes healing of simple, infected, non-healing, or burn wounds, as well as wounds in patients with diabetes, undergoing radiotherapy or steroid medication. Centella is also used for treating scars and preventing or reducing stretch marks. The extract of this plant promotes synthesis of collagen, hydroxyproline, hyaluronic acid and cell growth factors, thus helping to maintain the elasticity, strength and general appearance of healthy skin. It also protects the skin from ageing damage, such as glycation, and UV damage, likely by activating antioxidant synthesis.

NOTE: To assist you with solubility issues, we now also sell Centella asiatica as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 15% solution gives 1% triterpenes content in final product.
  • 43% solution gives 3% triterpenes content in final product.
  • 72% solution gives 5% triterpenes content in final product.
     

Key benefits of Centella asiatica in skin care:

  • Wound healing support [1] [2] [4] [5] [8]
  • Stimulate HA production [2]
  • Stimulate collagen production [2] [4] [5] [7]
  • reduce fine lines and wrinkles [2] [4] [5] [7]
  • Increase skin elasticity [2]
  • Glycation inhibitor and repair [9]
  • Scar care [2] [4] [12]
  • Sun damage protection [9]
$23.40
Based on 2 reviews.
Ethyl Ascorbic Acid

Ethyl ascorbic acid is a molecule produced by modifying ascorbic acid, commonly known as vitamin C. This modification is done to increase the molecule’s stability and enhance its transport through skin, as pure vitamin C is easily degraded. In the body, the modifying group is removed and vitamin C is restored in its natural form. Thus, ethylascorbic acid retains the benefits of vitamin C, such as antioxidant activity. Furthermore, it is even more potent in reducing skin darkening after UV exposure. It even has some additional effects, not observed in pure ascorbic acid, such as promoting nerve cell growth or reducing chemotherapy damage. Finally, the slower release also ensures that no toxic effects are observed when using this vitamin C derivative.

Key benefits of Ethyl ascorbic acid in skin care:

  • Stimulate collagen production [5] [6]
  • Lightening & brightening [5] [7] [9] [9]
  • Treat hyperpigmentation [5] [7] [8] [9]
  • Sun damage protection [8] [9]
$16.10
Based on 1 reviews.
Ferulic acid (Natural)
Ferulic acid is a plant compound with numerous known health benefits. It is absorbed efficiently through skin, where it is effective as a strong antioxidant. Most often it is used in combination with vitamins C and E – this way, the individual benefits of each ingredient are strengthened, resulting in very effective UV protection. This combination even prevents DNA damage and cancer formation. The antioxidant protection is stable, remains safe from rubbing and sweating, and even resistant to natural chemical degradation, giving the product a long shelf-life. Ferulic acid alone is also beneficial, as it can restore collagen synthesis after UV exposure and thus reduce the symptoms of skin ageing. These properties make it a desirable component in sunscreens and antioxidant formulations.

NOTE: To assist you with solubility issues, we now sell Ferulic acid in three liquids: pre-dissolved solution, lipsome microemulsion, and ethosome microemulsion. Just add the liquid to your cream and mix well.
  • 6% pre-dissolved solution gives 0.5% Ferulic Acid content in final product.
  • 31% pre-dissolved solution gives 3% Ferulic Acid content in final product.
  • 51% pre-dissolved solution gives 5% Ferulic Acid content in final product.
Ferulic acid is commonly used in the Skinceuticals C+E Ferulic serum.  C E Ferulic is a revolutionary antioxidant combination that delivers advanced protection against photoaging by neutralizing free radicals, boosting collagen synthesis, and providing unmatched antioxidant protection. More protection means more youthful looking skin and better defense against environmental aging.

Key benefits of Ferulic acid in skin care:

  • Sun damage protection [4] [5]] [6] [7] [8] [9] [10]
  • Sun damage repair [9] [10] [13] [14]
  • Antioxidant [1] [3] [7] [8] [9]
  • Stimulate collagen production [13] [14]
  • Lightening & brightening [15]
  • Anti-androgenetic alopecia [3]
  • Stabilizes l ascorbic acid [5]
$8.30
Based on 1 reviews.
Gamma oryzanol

Gamma-oryzanol is an ingredient produced from rice bran. It contains several related molecules, build on a ferulic acid backbone, all of which share antioxidant properties. They are particularly useful in protecting lipids, such as oils, which makes oryzanol an attractive ingredient in oil-containing preparations. Furthermore, it helps reduce skin darkening from UV exposure, as well as ageing-related skin symptoms, such as roughness and wrinkling. Since gamma-oryzanol activates sebum glands, it can be used for alleviating various conditions causing dry skin. In respect to collagen degradation, oryzanol can slow down this process even more efficiently than vitamin C, thus resulting in thicker and smoother skin. At the moment, even more possible applications of oryzanol are being investigated, such as treating hair loss or preventing damage from chemotherapy. As gamma oryzanol is oil soluble, it is an ideal active to use instead of pure ferulic acid (which is alcohol soluble).

Key benefits of Gamma oryzanol in skin care:

  • Sun damage protection [4] [9] [11]
  • Antioxidant [2] [3] [5]
  • Increase skin elasticity [9]
  • Oil/sebum control [6]
  • Moisturizing and hydration [5] [6] [9]
  • Stimulate collagen production [9]
  • Lightening & brightening [9] [11]
  • Anti-androgenetic alopecia [12]
$6.90
Ginkgo Biloba

Ginkgo biloba is a unique tree species. Its leaf extract contains a diverse variety of molecules useful in cosmetics and pharmacology. Firstly, they are potent antioxidants, and can even activate the production of enzymes that neutralize free radicals. Combined with the anti-inflammatory effects, this extract provides an effective defense against UV radiation and ageing symptoms. Dermal applications of this extract can even lead to protection of other organs. Another major application of Ginkgo biloba is moisturizing the skin, which helps to increase its elasticity and visual appearance, even reducing the amount of wrinkles. Furthermore, this extract helps to maintain the barrier function of the skin – it reduces water loss through epidermis, thus reducing skin dryness and irritation. In combination with green tea extract, Ginkgo shows even stronger benefits in these areas.

NOTE: To assist you with solubility issues, we now also sell Ginkgo Biloba extract as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

Key benefits of Ginkgo Biloba in skin care:

  • Sun damage protection [1] [6] [8] [10] [11]
  • Sun damage repair [7] [10]
  • Antioxidant [1] [6]
  • Capillary health [6] [14]
  • Increase skin elasticity [2]
  • Moisturizing & hydration [2] [3] [4]
  • Restore barrier function [2] [3] [4] [5]
  • Reduce fine lines and wrinkles [2] [4] [9]
  • Anti-inflammatory [9] [12] [13]
$9.80
Glucosamine (N-Acetyl Glucosamine)

N-acetyl glucosamine is a compound with a wealth of uses for improving skin condition. It is a known precursor to hyaluronic acid, a major component of skin structure. Hyaluronic acid is essential for hydration and n-acetyl glucosamine has been shown to increase moisture. N-acetyl glucosamine helps heal wounds, increase collagen, and reduce acne. It reduces hyperpigmentation, especially when combined with niacinamide, a member of the vitamin B3 family. It has anti-oxidant and anti-inflammatory properties which allow it to help heal and prevent sun damage. Overall, this compound can help prevent premature aging and reduce signs of aging, such as wrinkles, especially when combined with niacinamide.

Key benefits of Glucosamine in skin care:

  • Stimulate HA production [2] [3] [4] [5] [6] [7] [8] [9] 10]
  • Moisturizing and hydration [2] [5] [9] [11]
  • Treat hyperpigmentation [2] [4] [9]
  • Wound healing support [2] [11]
  • Stimulate collagen production [11]
  • Scar care [2]
  • Anti-acne [2] [6]
  • Anti-inflammatory [2] [3]
  • Anti-oxidant [2] [7]
  • Sun damage repair [1] [7]
  • Sun damage protection [7]
  • Increase skin elasticity [5] [11]
  • Reduce fine lines and wrinkles [2] [10]
  • Matrix metalloproteinases [MMP] inhibitors [7]
$6.70
Based on 1 reviews.
Grape Seed oil
Oil extracted from grape seeds is a light, pleasant-smelling oil. It is easily absorbed into the skin. The oil is rich in many different bioactive compounds. It contains high amounts of fatty acids, particularly linoleic acid, that are important for retaining moisture and skin barrier function. Grape seed oil also contains phytosterols that have anti-inflammatory effects. The oil has small amounts of polyphenols, which are known to have anti-oxidant abilities and inhibit collagen degradation. Additionally, grape seed oil has small amounts of vitamin E, which is known to act as a strong anti-oxidant. Grape seed oil applied to skin aids in wound healing, collagen production, and defends against bacteria.

 Key benefits grape seed oil in skin care:

  • Anti-oxidant [6] [7] [9] [10]
  • Sun damage protection [9] [10]
  • Moisturizing and hydration [4]
  • Stimulate collagen production [7] [10]
  • Anti-bacterial [7]
  • Wound healing support [7]
  • Matrix metalloproteinases [MMP] inhibitor [7]
BulkActives' oils are cold pressed, without the use of solvents or chemicals.
 
$8.20
Green Tea (90% EGCG)
Green tea has numerous benefits in almost all aspects of skin care. The main active ingredient, EGCG, is a potent antioxidant, and protects skin from UV damage. This results in reduced wrinkling, increased collagen content, smoother skin, thicker and more elastic epidermis and other visual benefits. Green tea also helps to moisturize the skin and improves the long-term barrier capabilities. Among the numerous clinical benefits are antibacterial and antifungal effects, which make green tea useful in wound care. Most important health effect is the prevention of melanoma and other types of skin cancer, resulting partly from the EGCG capability to neutralize free radicals and activate DNA repair. Since the extract also reduces inflammation and sebum secretion, it is an effective treatment against acne. Finally, green tea has also been proven to reduce hair loss and follicle death. Active ingredient in Teamine™ and ReVive™ lines.

NOTE: To assist you with solubility issues, we now also sell Green Tea EGCG in a standardized, pre-dissolved solution. Just add the liquid to your cream and mix well.
  • 11% solution gives 1% EGCG content in final product.
  • 33% solution gives 3% EGCG content in final product.
  • 54% solution gives 5% EGCG content in final product.

Key benefits of Green Tea EGCG in skin care:

  • Sun damage protection [1] [2] [3] [4] [5]
  • Sun damage repair [1] [2] [3]
  • Antioxidant [1] [2] [3] [7]
  • Capillary health [19]
  • Moisturizing & hydration [8] [9] [11]
  • Reduce fine lines and wrinkles [10] [11]
  • Wound healing support [17] [18]
  • Oil/sebum control [12]
  • Lightening & brightening [6]
  • Restore barrier function [8] [9]
  • Anti-inflammatory [1]
  • Anti-acne [12] [13]
  • Anti-bacterial [13] [14] [16]
$7.20
Based on 2 reviews.
Hesperidin methyl chalcone
Hesperidin is a a plant flavonoid, found naturally in citrus fruits. It has numerous biological benefits, but it is poorly absorbed and transported in the body, hence a modified version, hesperidin methyl chalcone (HMC), is used in cosmetics. The best known effect of HMC is reduction of capillary permeability. This can be used to reduce dark circles and bags under the eyes or even treat varicose veins. It is also known to reduce melanin synthesis, thus lightening the skin, and it also protects skin from UV-caused damage and cell ageing. Furthermore, HMC restores the barrier function of the skin, improving hydration, regulating pH and promoting skin cell proliferation. Finally, it has an anti-inflammatory effect, and can even be used to reduce various types of pain caused by inflammation.

NOTE: To assist you with solubility issues, we now also sell Hesperidin methyl chalcone as a liquid standardized pre-dissolved solution. Just add the liquid to your cream and mix well.
  • 11% solution gives 1% Hesperidin content in final product.
  • 31% solution gives 3% Hesperidin content in final product.
  • 51% solution gives 5% Hesperidin content in final product.

Key benefits of Hesperidin methyl chalcone in skin care:

  • Sun damage protection [8] [11]
  • Capillary health [4] [5] [12]
  • Lightening & brightening [7] [8]
  • Reduce dark circles under the eyes [6]
  • Restore barrier function [1] [9] [10]
  • Anti-inflammatory [2] [5]
$10.20
Phytosterol

Phytosterols are a family of plant-produced molecules with diverse health benefits. In cosmetics, the ability to stimulate collagen production is most interesting. Together with antioxidant activity and down-regulation of collagen degrading enzymes, these abilities help repair damage in photoaged skin. Phytosterols also have anti-inflammatory properties, which are useful in UV protection, dermatitis treatment, and even cancer prevention. They are widely used in burn wound care – phytosterols were found to improve healing, improve scar appearance and possess analgesic properties, reducing the need of opiate drugs. Antimicrobial activity of phytosterols is also important in skin care, as it can be utilized in both wound care and general fight against infections, such as Candida. Finally, phytosterols regulate transport of cholesterol and thus sebum production – this may present a good treatment option for acne and other sebum-related conditions.

NOTE: To assist you with solubility issues, we now also sell Phytosterol in a standardized  pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 11% solution gives 1% Phytosterols content in final product.
    32% solution gives 3% Phytosterols content in final product.
    53% solution gives 5% Phytosterols content in final product.

Key benefits of Phytosterols in skin care:

  • Anti-inflammatory [2], [12]–[14]
  • Anti-bacterial [6], [7]
  • Oil/sebum control [8]
  • Anti-acne [8]
  • Sun damage protection [10], [11]
  • Stimulate collagen production [9]–[11]
  • Restore barrier function [5]
  • Matrix metalloproteinase (MMP) inhibitors [9]–[11]
  • Wound healing support [3]–[5]
  • Scar care [3]–[5]
$6.80
Pine Bark (95% Proanthocyanidins)
Pine bark extract is a mixture of organic molecules with various health and cosmetical benefits. The proanthocyanidins found in this mixture have strong antioxidant properties. They are also known to reduce inflammation and redness (erythema) resulting from it. Combined, these effects make pine bark extract a potent defense against UV radiation, and it can even prevent various types of skin cancer. Furthermore, toxic effects of metal ions can be alleviated by applying this extract. In postmenopausal women, this extract has been proven to reduce wrinkles and improve skin hydration. Additionally, the molecules found in pine bark maintain good blood vessel health – the extract can alleviate hypertension and help capillaries recover after injuries, making it useful in wound care.

NOTE: To assist you with solubility issues, we now also sell Pine Bark Proanthocyanidins as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.
  • 11% solution gives 1% Proanthocyanidins content in final product.
  • 32% solution gives 3% Proanthocyanidins content in final product.
  • 53% solution gives 5% Proanthocyanidins content in final product.

Key benefits of Pine bark Proanthocyanidins in skin care:
  • Sun damage protection [3], [6], [11]
  • Antioxidant [1], [2]
  • Increase skin elasticity [9]
  • Moisturizing and hydration [9]
  • Lightening & brightening [11]
  • Wound healing support [12], [13]
  • Capillary health [11]
  • Anti-inflammatory [3]–[5]
  • Water soluble!
$6.10
Pomegranate (40% Ellagic)
Pomegranates have been used in medicine since ancient times. The extract of this plant contains many compounds acting synergistically to produce strong antioxidant and anti-inflammatory effects. It also helps maintain collagen levels, both by promoting its synthesis and inhibiting collagen-degrading enzymes. Due to these properties, pomegranate extract has a range of benefits in UV protection – it can be used both to prevent and to reduce sunlight damage (photoageing) after exposure. Furthermore, it is an effective skin whitening agent, used to treat melasma and other hyperpigmentation problems. Finally, faster wound healing is observed when using this extract. Combined with antibacterial, antifungal, anti-inflammatory properties and the ability to increase collagen synthesis, this makes pomegranate extract beneficial in many aspects of wound care.

NOTE: To assist you with solubility issues, we now also sell Pomegranate Extract as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 25% solution gives 1% Ellagic Acid content in final product.
  • 75% solution gives 3% Ellagic Acid content in final product.
  • 13% solution gives 1% Polyphenols content in final product.
  • 39% solution gives 3% Polyphenols content in final product.
  • 65% solution gives 5% Polyphenols content in final product.

 Key benefits of Pomegranate extract in skin care:

  • Sun damage protection [4], [7], [8]
  • Sun damage repair [7]–[9]
  • Antioxidant [1]–[4]
  • Glycation inhibitor and repair [3]
  • Anti-bacterial [2], [16]
  • Lightening and brightening [6], [10]–[12]
  • Matrix metalloproteinase (MMP) inhibitors [8], [9]
  • Stimulate collagen production [9]
  • Treat hyperpigmentation [10]–[12]
  • Wound healing support [13]–[16]
  • Anti-inflammatory [6], [8], [15]
$6.30
Pomegranate Seed Oil
Seed oil extracted from the pomegranate fruit contains high amounts of fatty acids, particularly punicic acid. Pomegranate seed oil is the only seed oil with punicic acid, making this a unique extract. Punicic seed is known to have anti-oxidant and anti-inflammatory effects. Present in smaller amounts in this seed oil are estrogen-like compounds which have potential to alleviate menopausal symptoms. Studies with pomegranate seed oil show it acts as a powerful antioxidant by decreasing reactive oxygen species that harm the body. It also protects against sun damage, and can repair sun-related damage to the skin by increasing skin thickness and barrier cell replication. This effect also aids in wound healing and can reduce skin thinning with age.  

Key benefits of Pomegranate Seed Oil in skin care:

  • anti-oxidant [1][3][5][6][7][8][9][10][12]
  • anti-inflammatory [3][7][8][10)
  • sun damage repair [1][6][2]
  • sun damage protection [1][9]
  • wound healing support [2]
  • restore barrier function [2][11]
  • natural phyto estrogens [7]
  • moisturizing and hydration
BulkActives' oils are cold pressed, without the use of solvents or chemicals.

 
$17.80
Quercetin
Quercetin is a molecule belonging to a class of complex organic compounds called flavonoids. Quercetin is produced by many plants, notably onions. The most important effect of this molecule is neutralizing free radicals. Quercetin can achieve this directly, due to its antioxidative properties, or by binding iron ions, which play a strong part in the accumulation of free radicals. Therefore, quercetin is an important component in UV-protective cosmeceuticals. It can also reduce the inflammation, darkening and synthesis of collagen-degrading enzymes, caused by UV exposure. Furthermore, quercetin has benefits for wound care, as it improves both healing of new wounds and subsequent scar formation. It even has a positive effect on the lifespan of cells, slowing down processes of cell ageing.

NOTE: To assist you with solubility issues, we now also sell Quercetin as two liquids: standardized pre-dissolved solution and standardized ethosome microemulsion. Just add the liquid to your cream and mix well.
  • 11% solution gives 1% Quercetin content in final product.
  • 31% solution gives 3% Quercetin content in final product.
  • 51% solution gives 5% Quercetin content in final product.

Key benefits of Quercetin in skin care:

  • Sun damage protection [3], [5]–[7]
  • Sun damage repair [3], [5]
  • Lightening & brightening [8]
  • Treat hyperpigmentation [8]
  • Anti-inflammatory [6], [7]
  • Antioxidant [1]–[4], [14]
  • Scar care [11]–[13]
  • Wound healing support [9], [10]
$12.90
Safflower Seed Oil
Safflower is a plant mainly grown for the oil in its seeds. This oil contains the highest amount [70%] of linoleic oil of any plant oil. Linoleic acid is known to benefit the skin in many ways. It moisturizes and hydrates the skin, correcting fatty acid deficiencies that cause dry, itchy skin. Due to the high amount of linoleic acid, safflower oil can be used to heal wounds, burns, and acne. Safflower oil also contains oleic acid [15%]. Oleic and linoleic acids combined can be used to reduce the appearance of scars and increase collagen production.

Key benefits of Safflower seed oil:

  • Moisturizing and hydration [1, 3, 5, 8, 9]
  • restore barrier function [1, 3, 5, 8, 9]
  • Wound healing support [1, 2, 5]
  • Sun damage prevention [10]
  • Sun damage repair [8]
  • Anti-acne [8]
  • Anti-inflammatory [4]
  • Stimulate collagen production [6]
  • Scar care [2]
BulkActives' oils are cold pressed, without the use of solvents or chemicals.

 
$8.80
Salicylic Acid (Beta Hydroxy Acid)

Salicylic acid is a hydroxyl acid compound originally derived from willow tree bark. It has many useful effects on skin, the most prominent being its use as an anti-acne treatment. It penetrates deep into pores, removing trapped oil that can cause blemishes. Salicylic acid is a keratolytic compound, meaning it exfoliates the skin and sloughs off dead skin cells, leaving smooth skin. This makes it useful for treating scaly skin, as well as calluses and warts. It also has anti-inflammatory and anti-bacterial properties. Salicylic acid has been shown to influence photodamage by reducing hyperpigmentation and providing protection against UV exposure.

NOTE: To assist you with solubility issues, we now also sell Salicylic Acid (Beta Hydroxy Acid) as a pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 6.7% solution gives 1% Salicylic acid content in final product.
  • 13.3% solution gives 2% Salicylic acid content in final product.
  • 20% solution gives 3% Salicylic acid content in final product.
  • 26.7% solution gives 4% Salicylic acid content in final product.
  • 33.3% solution gives 5% Salicylic acid content in final product.
     

Key benefits of Salicylic acid in skin care:

  • Anti-acne [2] [4] [6] [9] [10]
  • Anti blackheads [2] [4]
  • Anti-inflammatory [1] [3] [4] [5]
  • Exfoliator [2] [6] [10]
  • Oil/sebum control [2] [4]
  • Pore refinement [2] [4]
  • Increase skin cell turnover [2] [5] [6] [10]
  • Treat hyperpigmentation [2] [7]
  • Reduce fine lines and wrinkles [2] [7]
  • Anti-bacterial [8] [10]
  • Sun damage protection [8]
  • Sun damage repair [7] [8]
$4.10
Based on 1 reviews.
Sclerotium Gum
Sclerotium gum is an active ingredient obtained through fermentation from hardened fungal masses of various types of fungi. The most common source is a parasitic fungus named Sclerotium rolfsii.  Due to its efficiency as a thickening agent, emulsifier and stabilizer, sclerotium gum is used in numerous applications in the industrial, food and pharmaceutical fields. Recent research showed that sclerotium gum is a compound perfectly suitable for topical delivery of pharmaceuticals and natural active ingredients. Besides providing the right viscosity and stability of the topical preparation, the gum also has multiple benefits for the skin. Sclerotium gum is high in polysaccharides, especially beta glucans, namely scleroglucan, and has multiple benefits for the skin: it protects the lipid barrier, prevents water loss, increases moisturization, protects and repair damaged skin, enhances the local immune response and increases collagen production and deposits.

Key benefits of Sclerotium Gum in skin care:

  • moisturizing and hydration [9][12][13]
  • anti-inflammatory [6] [10]
  • wound healing support [6] [10]
  • sun damage protection [10]
  • sun damage repair [10]
  • stimulate collagen production[11]
  • Anti-bacterial [11]
  • Antioxidant [10]
  • Restore barrier function [9][12][13]
 
  • Emulsion stabilizer
  • Improves flow of emulsions
  • Wide pH tolerance :: 5 to 12
  • Offers a nice feel to products
  • Viscosity not affected by high heat
  • Stable in extreme physical and chemical conditions
  • Creates smooth flowing gels / serums
  • Improves natural moisture levels in skin and hair
  • Gels the water phase for enhanced viscosity without stiffness
  • Outstanding suspending ability
  • Alternative to carbopol and Gelmaker Ultra
  • Moisturizer
$11.00
Silymarin
Silymarin is a flavonolignans complex that can be only found in the seeds of Milk thistle (Silybum marianum), a member of the Compositae family native to the Mediterranean, now widespread all over the world. It consists of a mixture of three bioflavonoids found in the fruit, seeds, and leaves of the milk thistle plant: silibinin, silidianin, and silicristin and a flavonoid – taxifolin. Silymarin has strong antioxidant properties (fold times vitamin E) several studies proving its free radical and ROS scavenging effects thus suitable especially for the prevention and treatment in several forms of epithelial cancer. Another area of application for the antioxidant properties of silymarin is topical skin care with results in UV protection, UV effects attenuation, Rosacea, Melasma, acne and other skin pigmentation conditions. The potent anti-inflammatory mechanisms of silymarin are used for wound management, with benefits especially for the patients with healing impairing diseases. Silymarin has very low toxicity and it is well tolerated thus appropriate for human consumption and use.

NOTE: To assist you with solubility issues, we now also sell Silymarin as two liquids: standardized pre-dissolved solution and standardized ethosome microemulsion. Just add the liquid to your cream and mix well.
  • 13% solution gives 1% Silymarin content in final product.
  • 38% solution gives 3% Silymarin content in final product.
  • 63% solution gives 5% Silymarin content in final product.
  • 34% solution gives 1%Silybin content in final product.
  • 67% solution gives 2% Silybin content in final product.

 
Key benefits of Silymarin in skin care:

  • Antioxidant [4] [5] [6] [7] [8]
  • Sun damage protection [10] [11]
  • Sun damage repair [12] [13]
  • Anti-acne [10] [15]  [17]
  • Anti-inflammatory [19] [20]
  • Lightening and brightening [16]
  • Treat hyperpigmentation [16]
  • Reduce Rosacea [10] [15]
$6.80
Sodium Ascorbyl Phosphate (SAP)
Vitamin C, or ascorbic acid, is one of nature’s most powerful antioxidants.As the natural aging process and environmental hazards increase the amount of free radicals in the skin, ascorbic acid and its derivatives can effectively neutralize these damaging agents and prevent further damage.Ascorbic acid has been shown to increase the synthesis of collagen in the skin to reduce the appearance of wrinkles and to block the melanin synthesis pathway, reducing age spots and lightening skin.Unfortunately, ascorbic acid is not stable in aqueous solutions and is quickly degraded.The hydrophilic ascorbic acid derivative sodium ascorbyl phosphate is significantly more shelf-stable in solutions and, as it is converted to ascorbic acid in skin, retains all of the skin-benefitting aspects of vitamin C.Therefore sodium ascorbyl phosphate is the ideal choice for anti-aging emulsion creams.

Key benefits of Sodium Ascorbyl Phosphate in skin care:

  • Anti-acne [7]  [8]
  • Antioxidant [3] [4] [6] [9] [10]
  • Increase skin elasticity [1] [4]
  • Reduce fine lines and wrinkles [1] [4]
  • Stimulate collagen production [1] [4]
  • Sun damage protection [9] [10]
  • Sun damage repair [9] [10]
  • Lightening and brightening [12]
  • Treat hyperpigmentation [12]
$10.30
Soy Isoflavones
Soy isoflavones are comparatively new in regards to cosmetic use, however, studies show they have multiple skin-benefitting properties.Isoflavones are structurally similar to estrogens and can activate estrogen signaling pathways, including collagen synthesis, to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and increase tissue hydration.Additionally isoflavones are powerful antioxidants that can halt and reverse the appearance of aging due to free radicals caused by sunlight and other environmental hazards.As such, soy isoflavones are useful in reducing redness of the skin and decreasing the appearance of dark spots.These properties make soy isoflavones ideal for use in anti-aging, moisturizing, and skin protecting creams.

Key benefits of Soy isoflavones on skin care:

  • Anti-inflammatory [6, 11, 12]
  • Antioxidant [3, 6]
  • Increase skin elasticity [1, 4, 5, 15]
  • Matrix metalloproteinase [MMP] inhibitors [9]
  • Moisturizing and hydration [5, 15]
  • Natural phytoestrogens [3, 15]
  • Reduce fine lines and wrinkles [1, 4, 5, 15]
  • Stimulate collagen production [1, 4, 5, 15]
  • Sun damage protection [3, 6, 11, 12, 14]
  • Sun damage repair [3, 6, 11, 12, 14]
  • Treat hyperpigmentation [3]
$9.70
Squalane Olive Oil
Squalane is a form of squalene, a natural component of sebum [oil] that acts as a barrier for the skin. It is structurally similar to many natural compounds that benefit the skin, such as β-carotene, and vitamins A, D, E, and K. Squalane’s most noted function is as an anti-oxidant. It depletes the amount of free radicals from UV rays that can cause damage to the skin. Squalane also moisturizes and hydrates, decreasing dryness, itching, and redness. With these characteristics, it restores barrier function to the skin. It can act as a detoxifier and may play a role in acne treatment. Squalane is also used to increase the absorption of preparations into the skin.

Key benefits of Squalane Olive Oil in skin care:

  • Anti-oxidant [1, 3, 6, 7, 9, 13]
  • Moisturizing and hydration [1, 2, 3, 6, 10]
  • Sun damage protection [6, 7, 10]
  • Increases skin elasticity [3, 6]
  • Anti-bacterial [6]
  • Anti-androgenic alopecia [8]
  • Restore barrier function [3]
  • Reduce fine lines and wrinkles [4]
  • Squalane Olive Oil is highly stable against oxidation.

 
$26.60
Tinosorb M (Bisoctrizole)
Tinosorb M is the first UV filter to combine the two worlds of organic filters and micro fine inorganic pigments: it is a 50% aqueous dispersion of colorless microfine organic particles, which are less than 200nm in size and is dispersible in the water phase of an emulsion. Tinosorb M exhibits the widest UV absorption and delivers triple action: UV absorption due to the intrinsic photostable organic molecule, light scattering and reflection as a result of its microfine structure. Combining Tinosorb M and Tinosorb S Aqua has a synergic effect on both UVA and UBV protection, thus an overall enhancement on SPF

Key benefits of Tinsosorb M in skin care:

  • Can be incorporated in sunscreens, but also in day care products as well as
  • Large coverage of the UV-13 and UV-A range
  • Photostable
  • Ease of formulation
  • Less UV absorber required
  • Excellent compatibility with cosmetic ingredients and other UV filters
  • Ability to photostabilize other UV filters
  • Synergistic effect with UV-13 filters (SPF booster)
$23.10
Tinosorb S Aqua (Bemotrizinol)
Tinosorb S Aqua is the new, water soluble version of the oil soluble Tinosorb S. Tinosorb S Aqua acts in the water phase to provide broadest-possible UV protection and photo-stability. It is highly efficient at low concentration, and can be processed cold. Combining Tinosorb M and Tinosorb S Aqua has a synergic effect on both UVA and UBV protection, thus an overall enhancement on SPF

Key benefits of Tinsosorb S Aqua in skin care:

  • Can be incorporated in sunscreens, but also in day care products as well as
  • Large coverage of the UV-13 and UV-A range
  • Photostable
  • Ease of formulation
  • Less UV absorber required
  • Excellent compatibility with cosmetic ingredients and other UV filters
  • Ability to photostabilize other UV filters
  • Synergistic effect with UV-13 filters (SPF booster)
$23.20
Vitamin E Natural Mixed Tocopherols
Natural Vitamin E Mixed Tocopherols is an active blend of natural mixed tocopherols containing naturally occurring d-alpha, d-beta, d-gamma and d-delta tocopherols. These are NATURAL tocopherols, they are NOT the synthetic, racemix dl-tocopherol or dl-tocopheryl acetate. 

Tocopherol is the most commonly used form of vitamin E in cosmetic products. α-tocopherol, one of four types of tocopherol, is the most abundant form of vitamin E naturally found in the skin. α and γ forms are excreted in sebum [oil] and act as a barrier for the skin. The amount of tocopherol in the skin decreases over time due to sun exposure. Tocopherols are strong anti-oxidants. Anti-oxidants help protect against skin aging. Tocopherols use their anti-oxidant ability to protect against sun damage and repair sun damage. They increase collagen production and protect existing collagen by inhibiting matrix metalloproteinase [MMP] that degrades collagen. Mixed tocopherols have anti-inflammatory properties and accelerate wound healing.
 

Key benefits of Vitamin E Mixed Tocopherols in skin care:

  • Antioxidant [1-15]
  • Sun damage protection [2, 4, 7, 8, 9, 14, 15]
  • Sun damage repair [12]
  • Anti-inflammatory [2, 5, 10, 14]
  • Wound Healing Support [5]
  • Matrix Metalloproteinase [MMP] inhibitors [11]
  • Stimulate collagen production [5]
  • Reduces fine lines and wrinkles [3]
$10.40
Vitamin E Natural Mixed Tocotrienols
Tocotrienol, a form of vitamin E, is known to be a natural powerful antioxidant that is quickly absorbed into the skin. It reduces damage involved with skin aging that is caused by harmful free radicals from UV light and ozone. Symptoms of skin aging include wrinkles, dryness, hyperpigmentation, and loss of elasticity. Tocotrienol increases collagen synthesis, which improves skin elasticity. It can also “unclog” skin burdened by excessive cholesterol. Toctrienol has anti-inflammatory properties and is able to reduce symptoms of allergic skin reactions. It can also help reduce the drying side effects of acne regimens such as benzoyl peroxide.

Natural Vitamin E Mixed Tocotrienols is an active blend of natural alpha tocopherol and alpha tocotrienol, beta tocotrienol, delta tocotrienol, and gamma tocotrienol.These are NATURAL tocotrienols, they are NOT synthetic.

Key Benefits of Vitamin E mixed Tocotrienols in skin care:

  • Antioxidant [1-10]
  • Sun damage protection [1, 3, 4, 5, 6, 7, 10]
  • Sun damage repair [1, 3, 4, 5, 6, 7, 8, 9, 10]
  • Anti-inflammatory [4, 6, 9]
  • Stimulate collagen production [1, 2, 3]
  • Increase skin elasticity [2, 3]
  • Restore barrier function [8]
  • Treat hyperpigmentation [11]
$10.40
Wheat Germ Oil
Wheat germ is the embryo from a wheat kernel. Oil produced from wheat germ is high in vitamins E, D, and A. It contains reasonable amounts of carotenoids [bioactive pigments] that are important for skin health, particularly lutein. Additionally, wheat germ oil contains large amounts of fatty acids such as linoleic, oleic, and palmitic acids. The compounds in wheat germ provide anti-oxidant protection. They are able to scavenge free radicals from UV light and ozone that harm the skin. Together, they hydrate and moisturize the skin, protect against sun damage, increase skin elasticity, and reduce inflammation.

Key benefits of Wheat Germ oil in skin care:

  • Antioxidant [3, 6, 8, 9, 12]
  • Anti-inflammatory [1, 10]
  • Sun damage protection [5, 8, 11]
  • Sun damage repair [7, 13]
  • Reduces fine lines and wrinkles [9]
  • Moisturizing and hydration [4, 7, 9, 10, 13]
  • Stimulate collagen synthesis [11]
  • Increase skin elasticity [4, 8, 9]
  • Scar Care [9]
BulkActives' oils are cold pressed, without the use of solvents or chemicals.

 
$10.60
Yeast Beta Glucan

Glucan is a polymer, produced from glucose molecules in fungi, seaweed and other organisms. Many types of this polymer exist, but yeast beta-glucan has the optimal structure and size for biological activity. It has significant effects in wound healing – glucan is already used to treat burn patients, as it promotes regeneration of the skin, reduces pain and improves scar appearance. Furthermore, it is able to activate the immune system to fight against infections, making it additionally useful in open wound care. Additionally, it helps the skin to maintain its barrier function after damage by chemicals, such as detergents. The antioxidant properties of this polymer help protect the skin cells against UV or other sources of oxidative damage. Skin ageing symptoms, such as darkening, sunburn and collagen degradation, can also be reduced by applying this compound.


Key benefits of Yeast Beta Glucan in skin care:

  • Sun damage protection [1], [5], [11]
  • Sun damage repair [1], [5], [11]
  • Wound healing support [1], [4]–[8]
  • Anti-bacterial [9], [10]
  • Scar care [8]
  • Lightening & brightening [1]
  • Antioxidant [1], [5], [11]
  • Restore barrier function [5]
$10.50
Zinc Oxide Dispersion

Zinc Oxide Dispersion is a non-nano, uncoated, homogeneous dispersions of Zinc Oxide in Mineral Oil and Caprylic- Capric Triglyceride. Non-nano Zinc Oxide is safe because there are no nanopartices. The homogeneous Zinc Oxide dispersion makes it easy to process and use in DIY skin care (just add to a cream), no high shear mixing is required. Zinc Oxide is a highly effective inorganic physical sunscreen with broad spectrum UVA and UVB activity and coverage. Zinc Oxide is a physical sun protection sunscreen which absorbs & scatters UV light. Zinc Oxide offers mild and safe, long lasting UV protection, and does not degrade or oxidize.  250 gram of Zinc Oxide dispersion can make 1250 gram of final suncreen product if used at 20%.

Zinc oxide is a mineral produced by oxidation of zinc. Because of its reduced natural availability, zinc oxide is industrially produced.  Besides a wide utilization in industrial areas such as semiconductors, textiles and food, zinc oxide used in several medical products, most of them ointments and treatments that are meant for topical use. Due to its physical characteristics that ensure good coating of the stratum corneum, without intracellular invasion zinc oxide is used in rash protection ointments. Zinc also has healing and soothing properties, making it a common ingredient in soothing, calming and antiseptic lotions. One of the most encountered utilisation of zinc oxide is as a component of physical sunscreen lotions due to its full spectrum block properties, ZnO currently being the most effective substance in protecting against UVA and UVB radiation. Last but not least, because zinc is the second most present metal in the human body after iron, and thus part of every structure including stratum corneum, there are a lot of topical solutions against skin disorders such as acne, dandruff, rash, dermatitis.

Zinc Oxide Dispersion in skin care:

  • Sun damage protection [5] - [12]
  • Anti-acne [13]
  • Anti-inflammatory [14] [15] [16]
$57.00
Based on 1 reviews.
Magnesium Ascorbyl Phosphate (MAP)
Magnesium Ascorbyl  Phosphate (MAP) is a water soluble magnesium salt of  ascorbic acid. It is very stable, has great bioavailability and a neutral PH. On the skin, MAP has beneficial effects – similar to vitamin C: antioxidant, anti-inflammatory, boosts skin elasticity, lightening, hydrating, and wound healing, photo-protective. MAP is also easy to use and incorporate in DIY formulation both in aqueous and oil in water emulsions.


Key benefits of Magnesium Ascorbyl Phosphate (MAP) in skin care:

  • Antioxidant [3-15]
  • Increase skin elasticity [5] [11]
  • Stimulate collagen production [5] [11]
  • Sun damage protection [9] [10] [11]
  • Sun damage repair [9] [10] [11]
  • Lightening and brightening [12] [13] [14][15]
  • Treat hyperpigmentation [12] [13] [14][15]
$10.60
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