Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
Reviews
I wished i could order this in a smaller amount of 50 gr. Can i get informed when it is available ? -------------------- A. It will not be sold in smaller amounts. The review rating is meant to be for the product, not the size in which it is sold :-(.. ...»
Diana
Excellent quality, very fine texture and disperses easily when used correctly. Arrived in just seven days to London, England and with a reasonable postage fee. Very pleased... ...»
D N Bay
The best, most potent and most stable form of Vitamin C. Makes quite a difference to the appearance of mature, photo-damaged skin - don't expect results over night but with consistent use your skin will look more even and radiant!.. ...»
Judy
This ingredient has done more for my skin than anything else I've ever used. I put it into a spray facial toner and use it morning and night. I noticed the effects immediately, they were that dramatic. I will use this forever, no question... ...»
Marie
I bought this product before and I am here to buy it again! A high quality product for really good price... .. Thanks!.. ...»
Raisa
Love the fine powder ascorbic acid. I use it in a recipe for skin care along with hyaluronic acid. I'm 65 years old and absolutely no one believes it 'cause I've been doing this for years... ...»
Kathy
As all products from bulkactives, this is a really great and high-quality DYI ingredient. Along with John's friendly, reliable and very efficient service, it makes a purchase from bulkactives a very pleasant experience... ...»
Sandra
Purchased this some time ago from BulkActives and here to buy some more! Great stuff!!!!.. ...»
Kathy
I've been using Bulkactives green tea EGCG for four years. No complaints, it blends nicely my DIY anti-aging cream. I can feel a bit of toning and definitely notice the anti-inflammatory effects on my skin. Two observations that keep the rating 4 stars instead of 5: (1) A package of green tea contains significantly less weight/volume than the package of grape seed extract that I order from bulkactives. The two are combined in equal amounts in the anti-aging cream, so I find myself running o.. ...»
Theresa Andrews
I mixed it with some other water actives like Glucosamine, Niacinamide, Glutathione etc into the Pre Liposome Microemulsion and the serum was very smooth and moisturizing. As it claims, it penetrates into the skin very well. I will mix it with oil soluble actives in my next batch. .. ...»
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We sell  COSMETIC RAW MATERIALS, which are meant to be used at an appropriate percentage in a cosmetic formulation of your devising. Please do not order our products unless you know how to formulate creams and lotions with it!  

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Recent Articles

Antioxidants for sun damage protection (photoprotection)

How the skin naturally protects itself and the advantages of topical antioxidants for photoprotection The...

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Ascorbyl Glucoside in Skin Care (AA2G, stable Vitamin C)

Ascorbyl Glucoside or AA2G is a derivative of vitamin C that has been biochemically modified to make...

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Anhydrous C for skin care: L-ascorbic in silicone

Anhydrous C for skin care: absorption of L-ascorbic in a silicone base Anhydrous C is a skin care product...

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Enhancing skin tone and reversing the effects of ageing

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How to boost collagen production in skin

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Alcohol as Solvent in DIY Skin Care Products

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Hyperpigmentation,Melasma, and Skin Color Explained

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Improve skin tone and reverse the effects of aging

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Made in China - Getting to the Heart of the Matter

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Exfoliating: Mild Chemical Exfoliating in Skin Care

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Multi Lamellar Creams and Emulsions

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Oat Beta Glucan Skin Care

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UV Skin Damage - Photodamage and Photoaging

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Skin Lightening Process and Pigmentation Formation

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Resveratrol – nature’s most powerful and potent anti-aging agent yet

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Rosehip Oil and Vitamin A in Skin Care

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Silymarin Skin Health – Antioxidant & Anti-inflammatory

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Exfoliating Skin with Salicylic Acid

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soy isoflavones skin benefits

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Sunscreens With Vitamin A are Potentially Harmful for Skin

Sunscreens With Vitamin A are Potentially Harmful for Skin The impact of vitamin A on skin health has...

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Antioxidants for sun damage protection (photoprotection)

How the skin naturally protects itself and the advantages of topical antioxidants for photoprotection The...

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Ascorbyl Glucoside in Skin Care (AA2G, stable Vitamin C)

Ascorbyl Glucoside or AA2G is a derivative of vitamin C that has been biochemically modified to make...

Read article

Anhydrous C for skin care: L-ascorbic in silicone

Anhydrous C for skin care: absorption of L-ascorbic in a silicone base Anhydrous C is a skin care product...

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Enhancing skin tone and reversing the effects of ageing

Enhancing skin tone and reversing the effects of ageing It is only in recent times that researchers...

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How to boost collagen production in skin

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Alcohol as Solvent in DIY Skin Care Products

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Hyperpigmentation,Melasma, and Skin Color Explained

The enzyme tyrosinase converts the amino acid tyrosine into melanin in the skin. Hyperpigmentation can...

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Improve skin tone and reverse the effects of aging

Latest developments in agents that improve skin tone and reverse the effects of aging Beauty, they say,...

Read article

Made in China - Getting to the Heart of the Matter

After getting a couple of emails about products manufactured in China, I wanted to take the time to write...

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Exfoliating: Mild Chemical Exfoliating in Skin Care

Exfoliating is a cosmetic procedure that involves the removal of dead skin cells that accumulate in the...

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Multi Lamellar Creams and Emulsions

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UV Skin Damage - Photodamage and Photoaging

UV skin damage: Photodamage, photoaging and other ways in which the skin changes due to exposure to UV...

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Skin Lightening Process and Pigmentation Formation

Pigmentation formation and skin lightening process Melanin is mainly responsible for skin pigmentation,...

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Resveratrol – nature’s most powerful and potent anti-aging agent yet

The process of aging is one that man has battled with for a long time. A lot of research has been done...

Read article

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Read article

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Read article

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Read article

soy isoflavones skin benefits

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glycation inhibitor and repair

Glycation (AGEs) inhibitors and repair in skin care

In healthy skin, mechanisms of damage repair are functional. When these mechanisms are impaired, there is an accumulation of damages from molecular modifications, which results in ageing of the skin. The modifications occur mainly in the dermal extracellular matrix (ECM), and glycation of its structural proteins is one of the many modifications that occurs during ageing.[1] Glycation is an intrinsic ageing process where glucose binds to proteins.

The carbonyl groups on free flowing glucose can react with the amino groups on proteins without enzymes and form reversible compounds called Amadori products. These products then undergo a series of complex reactions and form irreversible protein compounds called advanced glycation end-products (AGEs).[1] Just like roasting meat marinated with sugar, glycation reaction gives the proteins a brown color and they are fluorescent under a fluorescence microscope.

AGEs are reactive and can form cross links between targeted proteins through strong covalent bonds, making them less elastic and more prone to breakage, and it also interferes with the repair mechanisms.[1] Moreover, AGEs deplete hyaluronic acids (HA) from the skin,[2] and HA is crucial for maintaining the structure and volume of the skin tissue because it can hold substantial amounts of water.[3] The glycated proteins can be destroyed through natural protein turnover: old proteins being degraded with newly synthesized proteins taking their place.[4]

Other than protein turnover, there has also been documentations of a specific AGE recognizing receptor on macrophages (a type of white blood cell), and AGE-modified proteins are selectively internalized and hence destroyed by macrophages.[5] Furthermore, when exposed with AGEs, the fibroblasts, dendrocytes, and keratinocytes can increase the production of connective tissue such as collagens, speeding up its turnover through upregulating of an AGE receptor called RAGE.[6] However, activation of RAGE also facilitates inflammation and compromises skin integrity.[7]  

One of the main target proteins for glycation on ECM is collagen, and since it has a relatively slow turnover rate (about 15 years),[8] it is particularly susceptible to AGE accumulations. The rate of AGE accumulation is proportional to glucose concentration in addition to time. With the presence of fructose, the rate is ten times higher.[7] This is why diabetic patients (who have high circulating glucose and fructose) have more AGEs and abnormalities in their skin,[9][10][11][12] whereas in healthy subjects the glycation of collagen from age 20 to 85 only increases by 33%[10] or a 3.7% increase in collagen fluorescence per year.[13]

Sun exposure facilitates AGE formation, evident by more AGEs in sun-exposed area of skin compared to sun-protected ones.[14] Oxidative stress can also promote glycation,[15] and conversely glycation can produce reactive oxygen species which can further damage the skin. In addition, glycation induces other pathological pathways involved in ageing, such as inflammation.[1] Interestingly, dietary AGE consumption can also glycate target proteins,[16] and cooking methods such as grilling, frying, and roasting produce more AGEs than poaching, boiling, and steaming. Ingesting AGEs also have adverse metabolic effects through changing gut flora such as reducing the absorption of nutrients that can fight AGE formation.[16] The glycated and cross-linked protein aggregates are protease resistant,[15] meaning the protein degradation process is impeded, so prevention is really the key.


There are several ingredients that have been found that can highjack AGE formation.

Most strikingly, Centella asiatica extract has been shown to completely halt AGE formation facilitated by a glycating agent in human skin tissue in vitro.[17] Antioxidants can mitigate oxidative stress and help reduce glycation. Ellagic acid (found in pomegranate peel) has been shown to stimulate collagen synthesis and inhibit an enzyme that degrades collagen in vitro.[18] Vitamin C (also known as ascorbic acid) is required during collagen synthesis,[19] and its concentration is lower in aged skin.[20] Vitamin C treatment has been shown to stimulate collagen synthesis as well and rejuvenate aged skin in a double-blind, split-face study,[21] and a randomized, double-blind trial.[22] Carnosine has rejuvenating effects on fibroblasts and can protect the skin from glycation induced damages.[23] Last, a compound in green tea called (-)-epigallocatechin-3-gallate, also known as EGCG, has been shown to reduce oxidative stress and inflammation and protect the skin from ultraviolet light induced ageing.[24] On the other hand, HA supplementation has been shown to stimulate fibroblast proliferation in vitro,[25] which can help restore the lost volume associated with glycation and ageing.[26]

In summary, glycation is a chemical reaction between reduced sugar and proteins which contributes to ageing. To mitigate glycation, one can lower dietary sugar and junk food consumption, reduce dietary AGEs by changing cooking methods, protect the skin from sun exposure, and utilize topical treatments such as Centella asiatica extract, pomegranate extract, ascorbic acid, carnosine, green tea extract, and hyaluronic acid.


References:

[1]          P. U. Giacomoni and G. Rein, “Factors of skin ageing share common mechanisms,” Biogerontology, vol. 2, no. 4, pp. 219–229, 2001.
[2]          Y. Okano, H. Masaki, and H. Sakurai, “Dysfunction of dermal fibroblasts induced by advanced glycation end-products (AGEs) and the contribution of a nonspecific interaction with cell membrane and AGEs,” J. Dermatol. Sci., vol. 29, no. 3, pp. 171–180, Sep. 2002.
[3]          U. Anderegg, J. C. Simon, and M. Averbeck, “More than just a filler - the role of hyaluronan for skin homeostasis,” Exp. Dermatol., vol. 23, no. 5, pp. 295–303, May 2014.
[4]          J. D. Furber, “Extracellular glycation crosslinks: prospects for removal,” Rejuvenation Res., vol. 9, no. 2, pp. 274–278, 2006.
[5]          H. Vlassara, J. Valinsky, M. Brownlee, C. Cerami, S. Nishimoto, and A. Cerami, “Advanced glycosylation endproducts on erythrocyte cell surface induce receptor-mediated phagocytosis by macrophages. A model for turnover of aging cells,” J. Exp. Med., vol. 166, no. 2, pp. 539–549, Aug. 1987.
[6]          C. Lohwasser, D. Neureiter, B. Weigle, T. Kirchner, and D. Schuppan, “The receptor for advanced glycation end products is highly expressed in the skin and upregulated by advanced glycation end products and tumor necrosis factor-alpha,” J. Invest. Dermatol., vol. 126, no. 2, pp. 291–299, Feb. 2006.
[7]         A. Goldin, J. A. Beckman, A. M. Schmidt, and M. A. Creager, “Advanced glycation end products: sparking the development of diabetic vascular injury,” Circulation, vol. 114, no. 6, pp. 597–605, Aug. 2006.
[8]         N. Verzijl, J. DeGroot, S. R. Thorpe, R. A. Bank, J. N. Shaw, T. J. Lyons, J. W. J. Bijlsma, F. P. J. G. Lafeber, J. W. Baynes, and J. M. TeKoppele, “Effect of Collagen Turnover on the Accumulation of Advanced Glycation End Products,” J. Biol. Chem., vol. 275, no. 50, pp. 39027–39031, Dec. 2000.
[9]          M. Melling, W. Pfeiler, D. Karimian-Teherani, M. Schnallinger, G. Sobal, C. Zangerle, and E. J. Menzel, “Differential scanning calorimetry, biochemical, and biomechanical analysis of human skin from individuals with diabetes mellitus,” Anat. Rec., vol. 259, no. 3, pp. 327–333, Jul. 2000.
[10]        D. G. Dyer, J. A. Dunn, S. R. Thorpe, K. E. Bailie, T. J. Lyons, D. R. McCance, and J. W. Baynes, “Accumulation of Maillard reaction products in skin collagen in diabetes and aging,” J. Clin. Invest., vol. 91, no. 6, pp. 2463–2469, Jun. 1993.
[11]        M. A. van Boekel, “The role of glycation in aging and diabetes mellitus,” Mol. Biol. Rep., vol. 15, no. 2, pp. 57–64, May 1991.
[12]        J. D. Méndez, J. Xie, M. Aguilar-Hernández, and V. Méndez-Valenzuela, “Molecular susceptibility to glycation and its implication in diabetes mellitus and related diseases,” Mol. Cell. Biochem., vol. 344, no. 1–2, pp. 185–193, Nov. 2010.
[13]        P. R. Odetti, A. Borgoglio, and R. Rolandi, “Age-related increase of collagen fluorescence in human subcutaneous tissue,” Metabolism., vol. 41, no. 6, pp. 655–658, Jun. 1992.
[14]        K. Mizutari, T. Ono, K. Ikeda, K. Kayashima, and S. Horiuchi, “Photo-enhanced modification of human skin elastin in actinic elastosis by N(epsilon)-(carboxymethyl)lysine, one of the glycoxidation products of the Maillard reaction,” J. Invest. Dermatol., vol. 108, no. 5, pp. 797–802, May 1997.
[15]        S. Kikuchi, K. Shinpo, M. Takeuchi, S. Yamagishi, Z. Makita, N. Sasaki, and K. Tashiro, “Glycation--a sweet tempter for neuronal death,” Brain Res. Brain Res. Rev., vol. 41, no. 2–3, pp. 306–323, Mar. 2003.
[16]        J. O’Brien and P. A. Morrissey, “Nutritional and toxicological aspects of the Maillard browning reaction in foods,” Crit. Rev. Food Sci. Nutr., vol. 28, no. 3, pp. 211–248, 1989.
[17]        G. Maramaldi, S. Togni, F. Franceschi, and E. Lati, “Anti-inflammaging and antiglycation activity of a novel botanical ingredient from African biodiversity (CentevitaTM),” Clin. Cosmet. Investig. Dermatol., vol. 7, pp. 1–9, 2013.
[18]        M. N. Aslam, E. P. Lansky, and J. Varani, “Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells,” J. Ethnopharmacol., vol. 103, no. 3, pp. 311–318, Feb. 2006.
[19]        R. Myllylä, K. Majamaa, V. Günzler, H. M. Hanauske-Abel, and K. I. Kivirikko, “Ascorbate is consumed stoichiometrically in the uncoupled reactions catalyzed by prolyl 4-hydroxylase and lysyl hydroxylase,” J. Biol. Chem., vol. 259, no. 9, pp. 5403–5405, May 1984.
[20]        G. Rhie, M. H. Shin, J. Y. Seo, W. W. Choi, K. H. Cho, K. H. Kim, K. C. Park, H. C. Eun, and J. H. Chung, “Aging- and photoaging-dependent changes of enzymic and nonenzymic antioxidants in the epidermis and dermis of human skin in vivo,” J. Invest. Dermatol., vol. 117, no. 5, pp. 1212–1217, Nov. 2001.
[21]        R. E. Fitzpatrick and E. F. Rostan, “Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage,” Dermatol. Surg. Off. Publ. Am. Soc. Dermatol. Surg. Al, vol. 28, no. 3, pp. 231–236, Mar. 2002.
[22]        P. G. Humbert, M. Haftek, P. Creidi, C. Lapière, B. Nusgens, A. Richard, D. Schmitt, A. Rougier, and H. Zahouani, “Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo,” Exp. Dermatol., vol. 12, no. 3, pp. 237–244, Jun. 2003.
[23]        A. R. Hipkiss, C. Brownson, M. F. Bertani, E. Ruiz, and A. Ferro, “Reaction of carnosine with aged proteins: another protective process?,” Ann. N. Y. Acad. Sci., vol. 959, pp. 285–294, Apr. 2002.
[24]      S. K. Katiyar, “Skin photoprotection by green tea: antioxidant and immunomodulatory effects,” Curr. Drug Targets Immune Endocr. Metab. Disord., vol. 3, no. 3, pp. 234–242, Sep. 2003.
[25]        R. M. Greco, J. A. Iocono, and H. P. Ehrlich, “Hyaluronic acid stimulates human fibroblast proliferation within a collagen matrix,” J. Cell. Physiol., vol. 177, no. 3, pp. 465–473, Dec. 1998.
[26]        J. Carruthers and A. Carruthers, “Hyaluronic acid gel in skin rejuvenation,” J. Drugs Dermatol. JDD, vol. 5, no. 10, pp. 959–964, Dec. 2006.
 
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Ascorbic Acid -L  (ultra fine powder)

L-ascorbic acid (vitamin C) is an essential nutrient which has many cosmetic benefits. It is a remarkable antioxidant and can scavenge reactive oxygen species and other free radicals, protecting the skin from oxidative stress. It can stimulate collagen synthesis by promoting cross-linking and stabilizing collagen molecules, upregulating collagen genes, increasing the transcription of the tissue inhibitor of matrix metalloproteinase 1, and inducing fibroblast proliferation. It reduces pigmentation by suppressing tyrosinase, which is important for melanin production. It is an anti-inflammatory agent and can be used to treat inflammatory skin disease such as erythema. Together, L-ascorbic acid provides powerful anti-aging properties and has been shown to reduce wrinkles, improve elasticity, and protect against sun damage. Stability and absorption of L-ascorbic acid is a concern. While the anhydrous L-ascorbic acid might be the most stable form, adding vitamin E not only helps stabilizing L-ascorbic acid, but the two have synergistic effects on anti-aging.  Used in: philosopy's turbo booster c powder and SkinCeuticals.

Key benefts of L-ascorbic acid in skin care:

  • Anti-inflammatory [31]
  • Antioxidant [4] [5] [6] [7] [8]
  • Increase skin elasticity [26]
  • Lightening and brightening [4] [22] [28] [29] [30]
  • Matrix metalloproteinases (MMP) inhibitors [19]
  • Moisturizing and hydration [21]
  • Reduce fine lines and wrinkles [7] [21] [22] [25] [26]
  • Ttimulate collagen production [5] [13] [14] [15] [16] [17] [18] [19] [20] [21] [22] [23] [24]
  • Sun damage protection [9] [11]
  • Sun damage repair [6] [22] [26]
  • Teat hyperpigmentation [4] [9] [22] [25] [28] [29] [30]
  • Wrinkle relaxers [22]
$6.50
Based on 4 reviews.
Ascorbyl Glucoside (Ascorbic Acid 2- Glucoside)
Ascorbyl glucoside (AA-2G) is a vitamin derivative, produced biologically by the reaction between glucose and vitamin C. This addition confers greater stability, compared to relatively unstable pure ascorbic acid, thus allowing for wide usage in pharmacy and cosmetics. AA-2G retains the antioxidant properties of the unmodified vitamin, therefore it is used to prevent radiation damage, cell senescence and skin darkening. It also promotes collagen synthesis, as well as cell proliferation – these mechanisms help improve the appearance of the skin and reduce wrinkles. Furthermore, since AA-2G does not release ascorbic acid instantly, all the listed positive effects are sustained longer and the possibility of adverse effects is reduced, compared to using pure ascorbic acid. All these qualities make AA-2G the most attractive vitamin C derivative for cosmetic use.

Key benefits of Ascorbyl glucoside (AA-2G)  in skin care:

  • Antioxidant [10] [16]
  • Lightening and brightening [14]
  • Treat hyperpigmentation [14]
  • Sun damage repair [10] [16]
  • Sun dammage protection [7] [9]
  • Stimulate collagen production [3] [13]
  • Reduce fine lines and wrinkles [12]
$25.00
Ascorbyl Tetraisopalmitate (Tetrahexyldecyl Ascorbate)

Ascorbyl tetraisopalmitate (Tetrahexyldecyl Ascorbate) is a molecule derived from vitamin C and isopalmitic acid. Pure vitamin C has several drawbacks for cosmeceutical use, most important of which is the low stability. Chemically modified vitamin molecules are more stable, and pure vitamin is released from the derivatives inside the body. Therefore, the effects of Tetrahexyldecyl Ascorbate are similar to those of vitamin C, most importantly it is able to act as an antioxidant. Ascorbyl tetraisopalmitate reduces the production of oxidizing agents, which contribute to cell damage after exposure to UV or chemical hazards. This effect is even stronger in the modified molecule than in pure vitamin C. Additionally, Tetrahexyldecyl Ascorbate protects against DNA damage and skin darkening caused by UV exposure. Finally, skin visual appearance is also improved by Ascorbyl tetraisopalmitate, as it promotes collagen synthesis and acts as a hydrating agent in reducing skin roughness.

Key benefits of Ascorbyl tetraisopalmitate in skin care:

  • Sun damage protection [1] [2] [7]
  • Sun damage repair [2]
  • Antioxidant [1] [6]
  • Moisturizing and hydration [5]
  • Stimulate collagen production [2]
  • Lightening & brightening [1]
  • treat hyperpigmentation [1]
$28.60
Based on 3 reviews.
Carnosine (L-Carnosine)
Carnosine is a compound from two amino acids, produced naturally in the human brain and muscles. Most likely, it performs a protective function – carnosine neutralizes metal ions and is a powerful antioxidant. It is used in skin care to combat oxidative damage to DNA and proteins, such as that caused by UV exposure. Furthermore, carnosine can protect proteins, primarily collagen, from glycation. These qualities make it a promising molecule in the fight against ageing, as carnosine not only protects cellular components, but can improve the visual appearance, reduce roughness and fine lines. It also maintains the barrier function of the skin, both by simple hydration and complex effects in wound healing. Carnosine applications are of special importance to diabetes patients, as it helps alleviate several complications of this disease, among them xerosis, rapid AGE production, and impaired wound healing.

Key benefits Carnosine in skin care:

  • Glycation inhibitor and repair [1] [9]
  • Sun damage protection [3] [4]
  • Sun damage repair [3] [4]
  • Wound healing support [11] [12]
  • Moisturizing & hydration [13] [14]
  • Antioxidant [4] [5] [6]
  • Restore barrier function [8]
$14.50
Centella asiatica (Gotu Kola)

Centella asiatica is a tropical plant that has been used extensively in Indian medicine. It has diverse applications for skin cosmetics: firstly, it is effective in wound care, as it promotes healing of simple, infected, non-healing, or burn wounds, as well as wounds in patients with diabetes, undergoing radiotherapy or steroid medication. Centella is also used for treating scars and preventing or reducing stretch marks. The extract of this plant promotes synthesis of collagen, hydroxyproline, hyaluronic acid and cell growth factors, thus helping to maintain the elasticity, strength and general appearance of healthy skin. It also protects the skin from ageing damage, such as glycation, and UV damage, likely by activating antioxidant synthesis.

NOTE: To assist you with solubility issues, we now also sell Centella asiatica as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 15% solution gives 1% triterpenes content in final product.
  • 43% solution gives 3% triterpenes content in final product.
  • 72% solution gives 5% triterpenes content in final product.
     

Key benefits of Centella asiatica in skin care:

  • Wound healing support [1] [2] [4] [5] [8]
  • Stimulate HA production [2]
  • Stimulate collagen production [2] [4] [5] [7]
  • reduce fine lines and wrinkles [2] [4] [5] [7]
  • Increase skin elasticity [2]
  • Glycation inhibitor and repair [9]
  • Scar care [2] [4] [12]
  • Sun damage protection [9]
$23.40
Based on 2 reviews.
Ethyl Ascorbic Acid

Ethyl ascorbic acid is a molecule produced by modifying ascorbic acid, commonly known as vitamin C. This modification is done to increase the molecule’s stability and enhance its transport through skin, as pure vitamin C is easily degraded. In the body, the modifying group is removed and vitamin C is restored in its natural form. Thus, ethylascorbic acid retains the benefits of vitamin C, such as antioxidant activity. Furthermore, it is even more potent in reducing skin darkening after UV exposure. It even has some additional effects, not observed in pure ascorbic acid, such as promoting nerve cell growth or reducing chemotherapy damage. Finally, the slower release also ensures that no toxic effects are observed when using this vitamin C derivative.

Key benefits of Ethyl ascorbic acid in skin care:

  • Stimulate collagen production [5] [6]
  • Lightening & brightening [5] [7] [9] [9]
  • Treat hyperpigmentation [5] [7] [8] [9]
  • Sun damage protection [8] [9]
$16.10
Based on 1 reviews.
Green Tea (90% EGCG)
Green tea has numerous benefits in almost all aspects of skin care. The main active ingredient, EGCG, is a potent antioxidant, and protects skin from UV damage. This results in reduced wrinkling, increased collagen content, smoother skin, thicker and more elastic epidermis and other visual benefits. Green tea also helps to moisturize the skin and improves the long-term barrier capabilities. Among the numerous clinical benefits are antibacterial and antifungal effects, which make green tea useful in wound care. Most important health effect is the prevention of melanoma and other types of skin cancer, resulting partly from the EGCG capability to neutralize free radicals and activate DNA repair. Since the extract also reduces inflammation and sebum secretion, it is an effective treatment against acne. Finally, green tea has also been proven to reduce hair loss and follicle death. Active ingredient in Teamine™ and ReVive™ lines.

NOTE: To assist you with solubility issues, we now also sell Green Tea EGCG in a standardized, pre-dissolved solution. Just add the liquid to your cream and mix well.
  • 11% solution gives 1% EGCG content in final product.
  • 33% solution gives 3% EGCG content in final product.
  • 54% solution gives 5% EGCG content in final product.

Key benefits of Green Tea EGCG in skin care:

  • Sun damage protection [1] [2] [3] [4] [5]
  • Sun damage repair [1] [2] [3]
  • Antioxidant [1] [2] [3] [7]
  • Capillary health [19]
  • Moisturizing & hydration [8] [9] [11]
  • Reduce fine lines and wrinkles [10] [11]
  • Wound healing support [17] [18]
  • Oil/sebum control [12]
  • Lightening & brightening [6]
  • Restore barrier function [8] [9]
  • Anti-inflammatory [1]
  • Anti-acne [12] [13]
  • Anti-bacterial [13] [14] [16]
$7.20
Based on 2 reviews.
Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 Liposome Emulsion
The Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 peptides liposome emulsion contains the peptides pal-ghk and pal-gqp acting in synergy to repair the cutaneous damages of age. By activating the skin’s natural production of collagen, elastin and hyaluronic acid, the peptides work to reduce wrinkles and other signs of aging. Collagen, made up of long strands of amino acids, is really the main building block of skin, giving the skin its smooth, and youthful appearance. As we age, collagen is lost, and this gives way to aged, wrinkled looking skin. When the long strands of amino acids in collagen are broken down they create small chains commonly referred to as peptides. The presence of these peptides signal to the skin that it has lost collagen and the production of more is necessary. The peptides Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 work to mimic the appearance of this broken down collagen, causing your skin to react by producing more collagen, as well as elastin (responsible for the skin’s elasticity, and  hyaluronic acid (which plumps up the skin and gives it that healthy, full look).

Key benefits of the peptides Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 liposome emulsion in skin care:

  • reduce fine lines and wrinkles
  • stimulate HA production
  • glycation inhibitor and repair
  • increase skin elasticity
  • moisturizing and hydration
  • stimulate collagen production
  • sun damage repair

BulkActives Peptide Liposome Emulsion

  • Palmitoyl oligopeptide (PAL GHK) 260ppm  
  • Palmitoyl tetrapeptide-7 ppm (PAL GQPR) 140ppm
  • Twice the strength of Matrixyl 3000
$19.95
Based on 8 reviews.
Pomegranate (40% Ellagic)
Pomegranates have been used in medicine since ancient times. The extract of this plant contains many compounds acting synergistically to produce strong antioxidant and anti-inflammatory effects. It also helps maintain collagen levels, both by promoting its synthesis and inhibiting collagen-degrading enzymes. Due to these properties, pomegranate extract has a range of benefits in UV protection – it can be used both to prevent and to reduce sunlight damage (photoageing) after exposure. Furthermore, it is an effective skin whitening agent, used to treat melasma and other hyperpigmentation problems. Finally, faster wound healing is observed when using this extract. Combined with antibacterial, antifungal, anti-inflammatory properties and the ability to increase collagen synthesis, this makes pomegranate extract beneficial in many aspects of wound care.

NOTE: To assist you with solubility issues, we now also sell Pomegranate Extract as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 25% solution gives 1% Ellagic Acid content in final product.
  • 75% solution gives 3% Ellagic Acid content in final product.
  • 13% solution gives 1% Polyphenols content in final product.
  • 39% solution gives 3% Polyphenols content in final product.
  • 65% solution gives 5% Polyphenols content in final product.

 Key benefits of Pomegranate extract in skin care:

  • Sun damage protection [4], [7], [8]
  • Sun damage repair [7]–[9]
  • Antioxidant [1]–[4]
  • Glycation inhibitor and repair [3]
  • Anti-bacterial [2], [16]
  • Lightening and brightening [6], [10]–[12]
  • Matrix metalloproteinase (MMP) inhibitors [8], [9]
  • Stimulate collagen production [9]
  • Treat hyperpigmentation [10]–[12]
  • Wound healing support [13]–[16]
  • Anti-inflammatory [6], [8], [15]
$6.30
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