Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
Reviews
I wished i could order this in a smaller amount of 50 gr. Can i get informed when it is available ? -------------------- A. It will not be sold in smaller amounts. The review rating is meant to be for the product, not the size in which it is sold :-(.. ...»
Diana
Excellent quality, very fine texture and disperses easily when used correctly. Arrived in just seven days to London, England and with a reasonable postage fee. Very pleased... ...»
D N Bay
The best, most potent and most stable form of Vitamin C. Makes quite a difference to the appearance of mature, photo-damaged skin - don't expect results over night but with consistent use your skin will look more even and radiant!.. ...»
Judy
Very good product. It performed exactly how I expected. .. ...»
Ryan
This ingredient has done more for my skin than anything else I've ever used. I put it into a spray facial toner and use it morning and night. I noticed the effects immediately, they were that dramatic. I will use this forever, no question... ...»
Marie
I bought this product before and I am here to buy it again! A high quality product for really good price... .. Thanks!.. ...»
Raisa
Love the fine powder ascorbic acid. I use it in a recipe for skin care along with hyaluronic acid. I'm 65 years old and absolutely no one believes it 'cause I've been doing this for years... ...»
Kathy
As all products from bulkactives, this is a really great and high-quality DYI ingredient. Along with John's friendly, reliable and very efficient service, it makes a purchase from bulkactives a very pleasant experience... ...»
Sandra
Purchased this some time ago from BulkActives and here to buy some more! Great stuff!!!!.. ...»
Kathy
I've been using Bulkactives green tea EGCG for four years. No complaints, it blends nicely my DIY anti-aging cream. I can feel a bit of toning and definitely notice the anti-inflammatory effects on my skin. Two observations that keep the rating 4 stars instead of 5: (1) A package of green tea contains significantly less weight/volume than the package of grape seed extract that I order from bulkactives. The two are combined in equal amounts in the anti-aging cream, so I find myself running o.. ...»
Theresa Andrews
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Recent Articles

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sun damage repair

Sun damage repair in skin care

As any living being, humans also need sun to exist. Sun light, besides being responsible for creating a proper living environment on Earth is also responsible for several metabolic processes in the human body (for example Vitamin D is metabolized during sun exposure). However, due to considerable changes in the human society, a more comfortable life style which involves less and less outdoor activitiesm and due to environmental development such as ozone depletion and pollution, sun exposure can become a danger if protection measures aren’t taken.

Skin, the barrier between the human body and the environment, is the most susceptible tissue to be damaged by sun.  Prolonged and unprotected sun exposure has several damaging effects from cutaneous manifestations such as erythema and inflammation on the epidermis to more profound ones such DNA damage and reactive oxygen species in the profound layers – dermis and hypodermis. Ultraviolet radiation (UVR), a component of the electromagnetic light spectrum shorter than the visible spectrum rays and longer than x-rays, is the main responsible for sun damage. UVR components are mostly absorbed by the ozone layer except UVB – partially absorbed and UVA – not at all absorbed.  UVR is considered to be the most harmful and damaging natural radiation to living beings. Its effects on skin, depending of the time of the exposure can be superficial or profound. The longer the exposure, the greater and sometimes irreversible the damage. UVR is responsible or an aggravating factor for several skin conditions such as dryness, scaling, hypopigmentation, hyperpigmentation, photoaging, initiation and proliferation of non-malignant and malignant skin tumours.

Both UVA and UVB are categorized as carcinogenetic radiations, even though their mechanisms are different. While UVB is a tumor initiator mainly trough DNA mutation, UVA is a tumor accelerator by affecting the mitochondrial metabolism and exaggerating the reactive oxygen species (ROS) levels.

The process of DNA (DNA – dezoxiribonucleic acid) damage is mainly caused by UVB radiation which directly harms the proteins from the double helix structure implicitly affecting the stored genetic information within skin cells, causing photoproducts. If not repaired properly, these specific lesions can lead to the development of skin cancer. Considering that DNA encodes the genetic information which is basically the cell instruction book for the form, structure, function and behaviour when it is threatened or destructed several mechanisms come into play. The damaged double helix protein structure is either repaired and if the operation fails to succeed cell death is scheduled. Sometimes under UVR exposure the DNA remains defective or incorrectly fixed. Such a mutation can proliferate and migrate thus being a serious threat for initiation and progress of skin cancer.

The process of oxidation is fundamental in living beings being responsible for the mitochondrial energy production. Reactive oxygen species (ROS) is an aggressive category of reactive ionized oxidants that is naturally produced as a by-product of oxidation in very low levels that are needed in certain metabolic reaction. Unfortunately the fine balance between demand and supply is affected by UVR exposure especially UVA. This an unwanted effect leads to increased free radicals and reactive oxygen species levels. Increased ROS levels are toxic to the cell that encloses them. [1][2][3]

Natural ingredients are only beginning to regain their rightful place in medicine including the dermatology and cosmetology fields after being ignored for years in the favor of pharmaceuticals. Some natural active ingredients have been used in medicine since the beginning of mankind and topical application of various mixtures for protection or healing purposes have been documented.
When it comes to sun damage protection and repair, numerous in vitro and in vivo studies proved that natural antioxidants used topically alone or in combination with chemical or physical sunscreen not only protect the skin against UVR related damage but even more, it repairs the damage, preventing it from proliferation.

Regular application of skin care products containing antioxidants proved to be beneficial in efficiently preparing the skin against exogenous oxidative stressors occurring during daily life and, sunscreening agents may also benefit from combination with antioxidants resulting in increased safety and efficacy of such photoprotective products [4].

The addition of botanical broad-spectrum sunscreen further decreases UV-induced damage compared with sunscreen alone. These agents have been shown to enhance protection against UV-induced epidermal effects. Non-sunscreen materials such as botanical extracts, antioxidants, and DNA repair enzymes can contribute value when applied topically to human skin in vivo [5].
In almost all cases, natural actives fight and repair UVR related damage on multiple levels: either directly – by free radicals and ROS scavenging or indirectly – by restoring enzymatic levels that allows the cell to self-repair.

Allantoin is the final product of the nitrogen metabolism in mammals but also naturally available in several plants. Topically applied it showed considerable reduction of sun-induced redness and erythema [6].

Alpha Bisabolol is an essential oil extracted from chamomile – a traditional medicinal plant – now available from sustainable and eco-friendly sources. Renowned especially for both its anti-inflammatory and tissue regeneration booster properties alpha bisabolol proved to be topically effective in repairing epidermal sun damage [7].

Alpha Lipoic Acid (RS-ALA) is a natural occurring animal cofactor that peaks into young adults but decreases with aging. It is best known for its antioxidant properties and traditionally used in OTC oral supplements. RS-ALA as an ROS scavenger is superior even to Vitamin C and E and showed relevant results in sun damage repair at epidermal and dermal levels [8].

Ascorbic Acid (AA,Vitamin C)  with its more stable derivatives Ethyl Ascorbic Acid, Sodium Ascorbyl Phospate, Ascorbyl Glucoside (AA-2G,resulting from the reaction of Vit C and Glucose) and Ascorbyl Tetraisopalmitate (a derivate from Vitamin C and Isopalmitic Acid) is perhaps the most well known natural antioxidant. It counteracts the UVR exposure related damage by scavenging reactive oxygen species (ROS) including oxidized alpha-tocopherol thus implicitly restoring the Vitamin E levels in the skin. Vitamin C stops the sun damage proliferation and even reverses its effects speeding the epidermis recovery [9][10][11].
 
Baobab Oil, preferably from an organic source, is a natural extract from the baobab tree, rich in fatty acids. Studies have proved to help in repairing sunburn and photo-aging, chronic skin damage due to excessive sun exposure [12].

Boswellic Acid, extracted from the Boswellia Serata tree is an effective active ingredient in preventing long term UVR damage such as photoaging. Clinical studies showed considerable improved appearance of fine lines and skin roughness associated with photoaging and increased skin thickness [13].

L-Carnitine is a natural occurring substance in the animal tissue, including skin, vital for the glucose and fat metabolisms. At the dermal and epidermal levels is known to prevent DNA damage and boost repair by restoring the glycation processes balance. It is usually mixed with Vitamin C and/or E in topical treatments [14].

Centella Asiatica an extract obtained from the tropical plant Gotu Kola is traditionally and extensively used in Indian medicine. This botanical active showed relevant results both in sun damage protection and repair when used topically by complex mechanisms of reducing glycation processes and implicitly slowing the oxidative damage [15].

CoEnzyme Q10 is one of the most popular skin care active ingredients. A natural occurring enzyme it is involved in the energy metabolism of animal cells. Due to its antioxidant properties efficiency in sun damage repair was tested with relevant results. Topically applied CoQ10 mixtures proved to boost the repair mechanism 2 to 3 times the normal rate [16].

D- panthenol the stable alcohol form of pantothenic acid (vitamin B5) is involved in the process of reducing UV induced erythema.  The efficacy of the active was assessed by colorimetry via the reduction of redness and by measuring the change in microcirculation by laser Doppler [17]. 

Ferulic Acid, preferably from a natural source, is an organic acid found in several plants, especially cereals as rice bran. It proved to be effective in UV damage repair, especially in mixtures with Vitamin C and E. The combination prevents DNA damage and is excellent in ROS scavenging. Even standalone, topical applied ferulic acid is superior to each of the two vitamins when it comes to UVR induced damage repair [18].

Fucoidan, a dietary fiber extracted mainly from the brown seaweed, showed efficiency in repairing aggravated atopic dermatitis, a skin pathology where sun exposure is a potent allergen [19].
Gamma-oryzanol is a natural active ingredient obtained from rice bran, basically a bundle of sterols build on a ferulic acid structure. Due to its antioxidant properties it has the ability to prevent and repair sun damage and reverse photoaging by scavenging ROS and inhibiting sun-related DNA damage [20]

Ginkgo Biloba is a natural active extracted from the unique tree species with the same name, renowned for its potency and versatility. In vitro and in vivo studies showed that the ginkgo biloba components, especially the flavonoids repairs both cutaneous and derma sun damage by scavenging UV generated free radicals and additionally increasing the levels of ROS scavenging enzymes. [21]

Glucosamine is a natural precursor of the hyaluronic acid that proved to be a great resource for topical skin care. N-acetyl glucosamine increases activity of antioxidant enzymes reducing the amount of harmful free radicals and ROS produced after UV exposure, repairing and reversing photoaging effects and sun dmage [22].
 
Grape seed oil with a high fatty acid content, Grape seed proanthocyanidins - molecules with very strong antioxidant proprieties, and Rosveratrol – an  antioxidant active extracted from grapes and other botanical resources  are also used in both preventing and repairing sun damage. While the oil mainly repairs cutaneous manifestations of photoaging [23] the proanthocyanidins scavange ROS, reducing the oxidative agents to normal levels [24].

Green tea extract (90%ECCG) is a powerful, polyphenol rich antioxidant. Used in topical mixtures the green tea extract repairs the cutaneous effects of sun exposure such as erythema and scaling. It is also active in repairing DNA damage and preventing cell death following UV exposure by restoring the balance in the oxidation metabolism [25].

Gynostemma pentaphyllum extract is extracted from Jiaogulan - a plant from original from Asia and used for centuries in the Chinese traditional medicine. Its strong antioxidant makes a perfect candidate for sun damage repair topical treatment with relevant results in the ability to neutralize free radicals and stope the aggressive UV induced oxidation process [26].

Hesperidin methyl chalcone is a stable version of hesperidin – an active usually extracted from citrus plants and a natural occurring flavonoid. Its action when topically applied reduces sun damage effects and also prevents damage proliferation trough DNA mutation, inhibiting the evolution of potential UV induced skin tumors [27]. Lemon peel bioferment is another active high in hesperidin.

Idebenone a bioengineered active identical with Coenzime Q10 can succesfuly replace its role in topical treatments, having the advantage of considerable higher availability. It is directly involved in the mitochondrial oxidation processes and helps maintain the balance and implicitly preventing premature cell aging and apoptosis [28]

Lactic Acid is another natural active extensively used in dermatology, including in sun damage prevention and repair. It proved to be extremely effective in multiple clinical in vivo studies in reducing the appearance of photoaging by both stimulating the production of extracellular matrix components – especially hyaluronic acid and by boosting the synthesis of lipids and ceramides – vital in repairing the skin barrier [29].

Niacinamide (Vitamin B3), a multipurpose cosmetical active agent is well known to have antioxidant effects by scavenging free radicals. This help repairing the DNA damaged by unprotected UVR exposure b is also an adjuvant in speeding the restoration of the skin surface  [30]

Pine bark extract contains active molecules called proanthocyanidins renowned for their very strong antioxidant properties effective in counter-acting ROS aggressiveness and reducing erythema caused by sun exposure. Topically applied, the extract reduces UVR related redness and inflammation and helps regulate the capillary growth and implicitly faster healing of the damage [31].
Pomegranate (40% ellagic acid) and highly rich in fatty acid Pomegranate seeds oil – are both efficient botanical actives used in topical skin protection against sun damage. Studies have shown that ellagic acid reduces UV-induced cell death, inflammatory processes, and even freezes cells in an non-dividing stage, giving them more time to repair their DNA. The seeds extract also proved to be effective in reducing fibroblasts apoptosis and decreasing ROS levels after UVR exposure [32].

Quercetin is a natural botanical flavonoid found especially in onion and related family. It is a very effective free radicals scavenger acting on two levels – directly or by binding iron – a vital metal in the ROS metabolism. It quickly restores and sometimes increases the anti-ROS enzyme levels, slowing, stopping and even reversing the effects of UVR skin damage [33]

Rosehip oil a natural source of Vitamin A showed wrinkle reducing in photoaged skin, elasticity restoration in scared skin and burned skin. Its effects are consistent in reducing photoaging appearance and attenuating erythema [34]

Safflower seed oil,extracted from Carthamus Tinctorius is popular for being high in fatty acids especially in  linoleic acid a multipurpose topic ingredient. It has multiple utilizations, one of them being the reduction of hyperpigmentation and other sun-related epidermal damage in UVR exposure [35].

Salicylic Acid (Beta Hydroxy Acid), a botanical active extracted from the seeds white willow bark is another effective protector against sun damage. Topically applied salicylic acid before prolonged sun exposure proved to reduce redness and inflammation in clinical trials [36].

Sylimarin, an extract from the seeds of Milk thistle has potent antioxidant activity has potential as an antiphotodamage and anticarcinogenic agent demonstrated in several clinical trials. The extract of is suitable for inclusion in topical skin care products and sunscreen as active ingredient being efficient in both UVR damage protection and repair [37].

Soy isoflavones are natural phytoestrogens with promising results in inhibiting UV-stimulated tyrosine kinases responsible for initiation of inflammation. Besides reducing it also protects the integrity of the dermal matrix and helping the skin recovery [38].

Squalane olive oil is a versatile active with numerous cosmetic uses. Its most important function is as an antioxidant and due to the fact that squalane is also found in the normal occurring skin sebum the protection against UVR damage is very natural and well tolerated [39].

Vitamin E, preferably natural, in its most stable and efficient forms tocopherols and tocotrienols is a popular ingredient in UVR protection topical mixtures. Both its forms proved to be efficient in preventing and repairing UVR related DNA damage, ROS scavenging and restoring oxidation processes to normal levels [40].

Wheat germ oil is known to be rich in vitamins A, D and E. The vitamin E in its component is proved to inhibit collagen degradation preventing and repairing photoaging effects [41].

Yeast beta glucan is a natural polymer occurring especially in fungi and algae. Its structure is optimized for skin penetration. In sun damage repair relevant results were observed especially in the reduction of UVB induced skin damage [42].

The success of a sun damage repair topical mixture is also determined by the vehicle/carrier used to deliver the active. In DIY it’s highly recommended to use multi-lamellar base creams with liquid crystal systems. Besides efficiently deliver the active ingredients it also moisturizes and help restores the skin barrier.
 

References:

[1]  World Health Organization, International Agency for Research on Cancer "Do sunscreens prevent skin cancer" Press release No. 132, June 5, 2000
[2]  World Health Organization, International Agency for Research on Cancer  Humans, Volume 55, November 1997
[3] S.R. Pinell, “Cutaneous photodamage, oxidative stress, and topical antioxidant protection”, J Am Acad Dermatol, pp:3-19,2003
[4] F. Dreher, H. Maibach, “Protective effects of topical antioxidants in humans”, Current Problems in Dermatology, 29, pp:157-164, 2001
[5]  M.S. Matsui, A.Hsia, J.D. Miller, K. Hanneman, H. Scull, K.D. Cooper, E.Baron, “ Non-sunscreen photoprotection: antioxidants add value to sunscreen”, J Investig Dermatol Symp Proc, 14, pp: a
[6]  C. Thornfeldt, “Cosmeceuticals Containing Herbs: Fact, Fiction, and Future,” Dermatol. Surg., vol. 31, pp. 873–881, Mar. 2006
[7]  J.K, Srivastava, M. Pandey, S. Gupta, “Chamomile, a novel and selective COX-2 inhibitor with anti-inflammatory activity”, Life Sciences. 85, pp:663-669, 2009
[8]  P. M. B. G. M. Campos, F. B. de Camargo Júnior, J. P. de Andrade, and L. R. Gaspar, “Efficacy of cosmetic formulations containing dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin,” Photochem. Photobiol., vol. 88, no. 3, pp. 748–752, Jun. 2012.
[9]  P. G. Humbert, M. Haftek, P. Creidi, C. Lapière, B. Nusgens, A. Richard, D. Schmitt, A. Rougier, and H. Zahouani, “Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo,” Exp. Dermatol., vol. 12, no. 3, pp. 237–244, Jun. 2003.
[10]   W.-Y. Huang, P.-C. Lee, L.-K. Huang, L.-P. Lu, and W. C. Liao, “Stability studies of ascorbic acid 2-glucoside in cosmetic lotion using surface response methodology,” Bioorg. Med. Chem. Lett., vol. 23, no. 6, pp. 1583–1587, Mar. 2013.
[11]  L. Xiao, K. Kaneyasu, Y. Saitoh, Y. Terashima, Y. Kowata, and N. Miwa, “Cytoprotective effects of the lipoidic-liquiform pro-vitamin C tetra-isopalmitoyl-ascorbate (VC-IP) against ultraviolet-A ray-induced injuries in human skin cells together with collagen retention, MMP inhibition and p53 gene repression,” J. Cell. Biochem., vol. 106, no. 4, pp. 589–598, Mar. 2009.
[12] G.P.P. Kamatou, I. Vermaak, and A.M. Viljoen, “An updated review of Adansonia digitata: A commercially important African tree,” South African Journal of Botany, vol. 77, issue 4, pp. 908– 919, October 2011.
[13]  A. Pedretti, R. Capezzera, C. Zane, E. Facchinetti, and P. Calzavara-Pinton, “Effects of Topical Boswellic Acid on Photo and Age-Damaged Skin: Clinical, Biophysical, and Echographic Evaluations in a Double-Blind, Randomized, Split-Face Study,” PlantaMed, vol. 76, pp. 550-560, Nov. 2009.
[14]    H. A. Khan and A. S. Alhomida, “A review of the logistic role of L-carnitine in the management of radiation toxicity and radiotherapy side effects,” J. Appl. Toxicol. JAT, vol. 31, no. 8, pp. 707–713, Nov. 2011.
[15] G. Maramaldi, S. Togni, F. Franceschi, and E. Lati, “Anti-inflammaging and antiglycation activity of a novel botanical ingredient from African biodiversity (CentevitaTM),” Clin. Cosmet. Investig. Dermatol., vol. 7, pp. 1–9, 2013.
[16]  Y. Yue, H. Zhou, G. Liu, Y. Li, Z. Yan, and M. Duan, “The advantages of a novel CoQ10 delivery system in skin photo-protection,”Int. J. Pharm., vol. 392, no. 1–2, pp. 57–63, Jun. 2010.
[17]  H.D.Tauschel,C.Rudolph, “Untersuchungen zur perkutanen Wirksamkeit einer Heparin-Allantoin-Dexpanthenol-Kombination in spezieller Salbengrundlage: Antiinflammatorische Wirkung auf UV-Erytheme am Meerschweinchen”, Arzneimittel Forschung, 32, pp. 1096-1100, 1982
[18]   J. C. Murray, J. A. Burch, R. D. Streilein, M. A. Iannacchione, R. P. Hall, and S. R. Pinnell, “A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation,” J. Am. Acad. Dermatol., vol. 59, no. 3, pp. 418–425, Sep. 2008.
[19]   A. Cantani, Pathogenesis of atopic dermatitis [AD] and the role of allergic factors. European review for medical and pharmacological sciences 5, 95-118 [2001].
[20]  C. Punvittayagul, K. Sringarm, C. Chaiyasut, and R. Wongpoomchai, “Mutagenicity and antimutagenicity of hydrophilic and lipophilic extracts of Thai northern purple rice,” Asian Pac. J. Cancer Prev. APJCP, vol. 15, no. 21, pp. 9517–9522, 2014.
[21]  R. Eli and J. A. Fasciano, “An adjunctive preventive treatment for cancer: ultraviolet light and ginkgo biloba, together with other antioxidants, are a safe and powerful, but largely ignored, treatment option for the prevention of cancer,” Med. Hypotheses, vol. 66, no. 6, pp. 1152–1156, 2006.
[22] Y.P. Hwang, H.G. Kim, E.H. Han, J.H. Choi, B.H. Park, K.H. Jung, Y.C. Shin, and H.G. Jeong, “N- Acetylglucosamine suppress collagenases activation in ultraviolet B-irradiated human dermal  fibroblasts: Involvement of calcium ions and mitogen-activated protein kinases,” Journal of Dermatological Science, vol. 63, pp. 93–103, 2011
[23] J. Shi, J. Yu, J.E. Pohorly, and Y. Kakuda, “Polyphenolics in Grape Seeds—Biochemistry and Functionality,” Journal of Medicinal Food, vol. 6, issue 4, pp. 291-299, 2003.
[24]   M. Vaid, R. Prasad, T. Singh, V. Jones, and S. K. Katiyar, “Grape seed proanthocyanidins reactivate silenced tumor suppressor genes in human skin cancer cells by targeting epigenetic regulators,” Toxicol. Appl. Pharmacol., vol. 263, no. 1, pp. 122–130, Aug. 2012.
[25]  N. Pazyar, A. Feily, and A. Kazerouni, “Green tea in dermatology,” Skinmed, vol. 10, no. 6, pp. 352–355, Dec. 2012.
[26] Y. Quan, Y. Yang, H. Wang, B. Shu, Q.-H. Gong, and M. Qian, “Gypenosides attenuate cholesterol-induced DNA damage by inhibiting the production of reactive oxygen species in human umbilical vein endothelial cells,” Mol. Med. Rep., vol. 11, no. 4, pp. 2845–2851, Apr. 2015.
[27] J. T. Bae, H. J. Ko, G. B. Kim, H. B. Pyo, and G. S. Lee, “Protective effects of fermented Citrus unshiu peel extract against ultraviolet-A-induced photoageing in human dermal fibrobolasts,” Phytother. Res. PTR, vol. 26, no. 12, pp. 1851–1856, Dec. 2012.
[28] M. Gold, MD, J. Biron, J. DiNardo, J. Lewis II, “Rapid Improvement of Photodamage by a Novel Anti-Aging Formulation”, The Dermatologist, 20,2012
[29]  M.J. Stiller, J. Bartolone, R. Stern, “Topical 8% glycolic acid and 8% l-lactic acid creams for the treatment of photodamaged skin: A double-blind vehicle-controlled clinical trial”,  Archives of Dermatology, 132, pp:631-636, 1996
[30] B.C. Thompson, D. Surjana, G.M. Halliday, and D.L. Damian, “Nicotinamide enhances repair of ultraviolet radiation-induced DNA damage in primary melanocytes,” Experimental Dermatology, 23, pp. 509–528, 2014
[31] C. Saliou, G. Rimbach, H. Moini, L. McLaughlin, S. Hosseini, J. Lee, R. R. Watson, and L. Packer, “Solar ultraviolet-induced erythema in human skin and nuclear factor-kappa-B-dependent gene expression in keratinocytes are modulated by a French maritime pine bark extract,” Free Radic. Biol. Med., vol. 30, no. 2, pp. 154–160, Jan. 2001.
[32] L. A. Pacheco-Palencia, G. Noratto, L. Hingorani, S. T. Talcott, and S. U. Mertens-Talcott, “Protective effects of standardized pomegranate (Punica granatum L.) polyphenolic extract in ultraviolet-irradiated human skin fibroblasts,” J. Agric. Food Chem., vol. 56, no. 18, pp. 8434–8441, Sep. 2008
[33]  F. T. M. C. Vicentini, T. He, Y. Shao, M. J. V. Fonseca, W. A. Verri, G. J. Fisher, and Y. Xu, “Quercetin inhibits UV irradiation-induced inflammatory cytokine production in primary human keratinocytes by suppressing NF-κB pathway,” J. Dermatol. Sci., vol. 61, no. 3, pp. 162–168, Mar. 2011.
[34]  A.C. Dweck, “The role of natural ingredients in anti-ageing of the skin,”­ Australian Society of Cosmetic Chemists Annual Congress, transcript, Hamilton Island, 2003.
[35]  D.F. Horrobin and B.M. DPhil, “Essential fatty acids in clinical dermatology,” Journal of the American Academy of Dermatology,” vol. 20, num. 6, pp. 1045-1053, June 1989.
[36] A. Kornhauser, S.G. Coelho, and V.G. Hearing, “Applications of hydroxy acids: classification, mechanisms, and photoactivity,” Clin Cosmet Investig Dermatol., vol. 3, pp. 135-142, 2010.
[37] Alena Svobodova, Jitka Psotova, Daniela Walterova, “Natural phenolics in the prevention of UV-induced skin damage. A Review”, Biomed. Papers 147(2), 137–145, 2003
[38] C.C. Miller, P. Hale, A,P, Pentland, “Ultraviolet B injury increases prostaglandin synthesis through a tyrosine kinase-dependent pathway. Evidence for UVB-induced epidermal growth factor receptor activation,”, Journal of Biological Chemistry. 1994;269[5]:3529-33.
[39] Y. Kohno, Y. Egawa, S. Itoh, S. Nagaoka, M. Takahashi, and K. Mukai, “Kinetic study of quenching reaction of singlet oxygen and scavenging reaction of free radical by squalene in n-butanol,” Biochimica et Biophysica Acta, vol. 1256, pp. 52-56, 1995.
[40] M. McVean and D.C. Liebler, “Prevention of DNA photodamage by vitamin E compounds and sunscreens: roles of ultraviolet absorbance and cellular uptake,” Mol Carcinog., vol. 24, issue 3, pp. 169-176, March 1999.
[41] J.J. Thiele, S.N. Hsieh, and S. Ekanayake-Mudiyanselage, “Vitamin E: Critical Review of Its Current Use in Cosmetic and Clinical Dermatology,” Dermatol Surg,vol. 31, pp. 805-813, 2005.
[42]    B. Du, Z. Bian, and B. Xu, “Skin Health Promotion Effects of Natural Beta-Glucan Derived from Cereals and Microorganisms: A Review,” Phytother. Res., vol. 28, no. 2, pp. 159–166, Feb. 2014.

 
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Allantoin

Allantoin is a natural product of nitrogen metabolism in several plants and most mammals. It has been used in numerous cosmetics products for a significant period of time and is proven safe for various human applications. Its greatest benefits are promotion of wound healing, including reduced scar formation after various procedures (ranging from surgical scars to tattoo removal). To this purpose, allantoin can be used preventively as well as on already formed scars. Furthermore, it is an effective antimicrobial substance, used in alcohol-free hand sanitizers. Allantoin-containing solutions have been used in treating various infections, primarily onychomycosis (nail fungus) and trichomoniasis. Its anti-inflammatory properties made it useful in dermatitis treatment. Generally, allantoin is combined with extracts of onion or other plants, but its effectiveness was also demonstrated while applying without supplements.

Key benefits of Allantoin in skin care:

  • Anti-inflammatory [2] [13]
  • Wound healing support [2] [4]
  • Anti-bacterial [9] [10] [11]
  • sun damage repair [2] [13]
  • Scar care [6] [7] [8]
$5.20
Alpha Bisabolol (sustainable)

EcoFriendly, sustainable, synthetic Alpha Bisabolol , which offers all the benefits of natural Alpha Bisabolol, is now available.
For thousands of years, chamomile has been a prized component of many ancient therapies.  The active ingredient of chamomile, α-bisabolol, is a lightly floral-scented essential oil extracted from the Candeia tree, a tropical relative of cammomile, in modern times. In order to produce 100 tons of α-bisabolol, 850 hectares of timber must be harvested . Due to deforestation amid a global high demand, synthetic sources of α-bisabolol are now available.  New generations of the synthetic compound offer 85% α-bisabolol content and all of the benefits of the natural product.  Easily absorbed by the skin, α-bisabolol is a potent anti-microbial agent, anti-inflammatory, and potent wound-care agent.   It has valuable applications in soaps, lotions, soothing face creams, and wound-healing products

Key benefits of Sustainable Alpha Bisabolol in skin care:

  • Anti-bacterial [1] [2] [3] [6]
  • Anti-acne [1] [2] [3] [6] [7]
  • Anti-inflammatory [1] [2] [3] [7]
  • Moisturizing and hydration [9]
  • Sun damage repair [1] [7]
  • Wound healing support [2] [9]
  • Reduce rosacea
$19.90
Alpha Lipoic Acid (RS-ALA)

Alpha-lipoic acid (ALA) is a naturally occurring antioxidant that also shows numerous attractive features for use in cosmetic skin care. It is known as a dietary supplement for a long time, but recent research suggests it may be more effective through other applications, such as skin creams. ALA neutralizes free radicals, thus helping to fight ageing and cancer. It is more effective in combating free radicals than common vitamins, such as vitamin C or E, hence lipoic acid is called the “universal antioxidant”. In skin care, ALA was also shown to promote wound healing, treat and prevent diabetic ulcers. Cosmetics research suggests that ALA can promote collagen synthesis, thus reducing the visible effects of ageing on skin, and improving the appearance without any noticeable side effects. Alpha Lipoic Acid is a key active ingredient in Perricone MD products

Key benefits of Alpha Lipoic Acid in skin care:

  • Antioxidant [1] [2] [5] [7] [8]
  • Anti-inflammatory [5] [7]
  • Stimulate collagen production [14]
  • Reduce fine lines and wrinkles [16] [15]
  • Sun damage protection [17] [19]
  • Sun damage repair [1] [2] [5] [7] [8] [16] [15]
  • Wound healing support [10] [11] [12]

 
$6.70
Ascorbic Acid -L  (ultra fine powder)

L-ascorbic acid (vitamin C) is an essential nutrient which has many cosmetic benefits. It is a remarkable antioxidant and can scavenge reactive oxygen species and other free radicals, protecting the skin from oxidative stress. It can stimulate collagen synthesis by promoting cross-linking and stabilizing collagen molecules, upregulating collagen genes, increasing the transcription of the tissue inhibitor of matrix metalloproteinase 1, and inducing fibroblast proliferation. It reduces pigmentation by suppressing tyrosinase, which is important for melanin production. It is an anti-inflammatory agent and can be used to treat inflammatory skin disease such as erythema. Together, L-ascorbic acid provides powerful anti-aging properties and has been shown to reduce wrinkles, improve elasticity, and protect against sun damage. Stability and absorption of L-ascorbic acid is a concern. While the anhydrous L-ascorbic acid might be the most stable form, adding vitamin E not only helps stabilizing L-ascorbic acid, but the two have synergistic effects on anti-aging.  Used in: philosopy's turbo booster c powder and SkinCeuticals.

Key benefts of L-ascorbic acid in skin care:

  • Anti-inflammatory [31]
  • Antioxidant [4] [5] [6] [7] [8]
  • Increase skin elasticity [26]
  • Lightening and brightening [4] [22] [28] [29] [30]
  • Matrix metalloproteinases (MMP) inhibitors [19]
  • Moisturizing and hydration [21]
  • Reduce fine lines and wrinkles [7] [21] [22] [25] [26]
  • Ttimulate collagen production [5] [13] [14] [15] [16] [17] [18] [19] [20] [21] [22] [23] [24]
  • Sun damage protection [9] [11]
  • Sun damage repair [6] [22] [26]
  • Teat hyperpigmentation [4] [9] [22] [25] [28] [29] [30]
  • Wrinkle relaxers [22]
$6.50
Based on 4 reviews.
Ascorbyl Glucoside (Ascorbic Acid 2- Glucoside)
Ascorbyl glucoside (AA-2G) is a vitamin derivative, produced biologically by the reaction between glucose and vitamin C. This addition confers greater stability, compared to relatively unstable pure ascorbic acid, thus allowing for wide usage in pharmacy and cosmetics. AA-2G retains the antioxidant properties of the unmodified vitamin, therefore it is used to prevent radiation damage, cell senescence and skin darkening. It also promotes collagen synthesis, as well as cell proliferation – these mechanisms help improve the appearance of the skin and reduce wrinkles. Furthermore, since AA-2G does not release ascorbic acid instantly, all the listed positive effects are sustained longer and the possibility of adverse effects is reduced, compared to using pure ascorbic acid. All these qualities make AA-2G the most attractive vitamin C derivative for cosmetic use.

Key benefits of Ascorbyl glucoside (AA-2G)  in skin care:

  • Antioxidant [10] [16]
  • Lightening and brightening [14]
  • Treat hyperpigmentation [14]
  • Sun damage repair [10] [16]
  • Sun dammage protection [7] [9]
  • Stimulate collagen production [3] [13]
  • Reduce fine lines and wrinkles [12]
$25.00
Ascorbyl Tetraisopalmitate (Tetrahexyldecyl Ascorbate)

Ascorbyl tetraisopalmitate (Tetrahexyldecyl Ascorbate) is a molecule derived from vitamin C and isopalmitic acid. Pure vitamin C has several drawbacks for cosmeceutical use, most important of which is the low stability. Chemically modified vitamin molecules are more stable, and pure vitamin is released from the derivatives inside the body. Therefore, the effects of Tetrahexyldecyl Ascorbate are similar to those of vitamin C, most importantly it is able to act as an antioxidant. Ascorbyl tetraisopalmitate reduces the production of oxidizing agents, which contribute to cell damage after exposure to UV or chemical hazards. This effect is even stronger in the modified molecule than in pure vitamin C. Additionally, Tetrahexyldecyl Ascorbate protects against DNA damage and skin darkening caused by UV exposure. Finally, skin visual appearance is also improved by Ascorbyl tetraisopalmitate, as it promotes collagen synthesis and acts as a hydrating agent in reducing skin roughness.

Key benefits of Ascorbyl tetraisopalmitate in skin care:

  • Sun damage protection [1] [2] [7]
  • Sun damage repair [2]
  • Antioxidant [1] [6]
  • Moisturizing and hydration [5]
  • Stimulate collagen production [2]
  • Lightening & brightening [1]
  • treat hyperpigmentation [1]
$28.60
Based on 3 reviews.
Baobab Oil Organic
Baobab seed oil is a highly moisturizing and skin smoothing therapeutic. It is rich in fatty acids, particularly linoleic [omega-6] and oleic [omega-9] acids. These fatty acids help restore the barrier function of skin, especially thin, aged skin. Baobab seed oil also contains healthy vitamins A, D, E, and F that rejuvenate skin. In addition to moisturizing, baobab seed oil aids in wound healing, collagen production, sun damage protection and repair, and can prevent wrinkles. It has anti-microbial, anti-inflammatory, and anti-oxidant properties. Overall, baobab seed oil can improve the softness and strength of all skin types, even irritated skin.

Key benefits of Baobab oil in skin care:

  • Moisturizing and hydration  [5] [9] [10] [11]
  • Restore barrier function [5] [6] [7] [9] [13]
  • Anti-inflammatory [5] [8] [9] [11]
  • Wound healing support [5] [9] [11]
  • Anti-bacterial [5] [6] [7]
  • Anti-oxidant [5] [9]
  • Increase skin elasticity [5] [9]
  • Anti-acne [5]
  • Sun damage protection [4]
  • Sun damage repair [5]
  • Oil/sebum control [11]
  • Stimulate collagen production [4]
BulkActives' oils are cold pressed, without the use of solvents or chemicals.

 
$27.20
Boswellia serrata (Boswelic acid)
Resin from the Boswella serrata tree found in parts of Asia and Africa is commonly used in traditional Ayurvedic medicine for a variety of disorders associated with inflammation. It has been used medicinally for centuries and is now gaining support through research. The main ingredients of the resin are boswellic acids. Boswellic acids have anti-inflammatory effects when applied topically. Preparations using either the resin or pure boswellic acid extracted from the resin can help treat inflammatory disorders such as osteoarthritis, eczema, and psoriasis. The extract helps reduce sun damage, fine lines, and acne. It stimulates collagen production. Also, it aids in wound healing and inhibits tumor growth. Research shows boswella serrata extract has a variety of useful anti-inflammatory effects and can help alleviate the symptoms of a variety of conditions. This extract has been popularized as Boswelox™ by L’Oreal and its Wrinkle-de-crease.

NOTE: To assist you with solubility issues, we now also sell Boswellia serrata (Boswelic acid) as a liquid standardized pre-dissolved solution. Just add the liquid to your cream and mix well.
  • 16% solution gives 1% Boswelic Acid content in final product.
  • 46% solution gives 3% Boswelic Acid content in final product.
  • 66% solution gives 5% Boswelic Acid content in final product.

Key benefits of Boswellia serrata in skin care:

  • Anti-inflammatory [1] [2] [3] [4] [5] [6] [7] [8] [9] [10]
  • Sun damage repair [1] [5]
  • Stimulate collagen production [1]
  • Reduce fine lines [1] [5]
  • Anti-bacterial [10]
  • Anti-acne [10]
  • Tumor inhibition [3]
  • Wound healing support [4]
$6.30
Carnitine (L-Carnitine)

Carnitine is a naturally occurring substance, necessary for fat and glucose metabolism in human body cells. Primary function of carnitine in pharmacy is the reduction of advanced glycation end products (AGEs). AGEs are proteins, damaged by reactions with sugars, therefore glycation is most prominent in diabetes patients. It also occurs in many other diseases, as well as natural ageing processes. Dermal carnitine applications reduce the level of glycated collagen and promote synthesis of new protein. Since it is involved in lipid metabolism, carnitine is used for acne treatment. It effectively reduces sebum secretion and skin oiliness. Carnitine preparations also improve other aspects of the skin, such as tonicity, and reduce cellulite. Finally, it aids skin regeneration after damage, such as burns, and promotes blood vessel formation.  Regretably, due to Candian law and PayPal regulations, this product may NOT be shipped to Canada.

Key beneftis of Carnitine in skin care:

  • Oil/sebum control [4] [5]
  • Glycation inhibition and repair [1] [3]
  • Increase cellular energy production [1] [3]
  • Anti-acne [5]
  • Restore barrier function [6] [7]
  • Wound-healing support [8]
$6.60
Centella asiatica (Gotu Kola)

Centella asiatica is a tropical plant that has been used extensively in Indian medicine. It has diverse applications for skin cosmetics: firstly, it is effective in wound care, as it promotes healing of simple, infected, non-healing, or burn wounds, as well as wounds in patients with diabetes, undergoing radiotherapy or steroid medication. Centella is also used for treating scars and preventing or reducing stretch marks. The extract of this plant promotes synthesis of collagen, hydroxyproline, hyaluronic acid and cell growth factors, thus helping to maintain the elasticity, strength and general appearance of healthy skin. It also protects the skin from ageing damage, such as glycation, and UV damage, likely by activating antioxidant synthesis.

NOTE: To assist you with solubility issues, we now also sell Centella asiatica as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 15% solution gives 1% triterpenes content in final product.
  • 43% solution gives 3% triterpenes content in final product.
  • 72% solution gives 5% triterpenes content in final product.
     

Key benefits of Centella asiatica in skin care:

  • Wound healing support [1] [2] [4] [5] [8]
  • Stimulate HA production [2]
  • Stimulate collagen production [2] [4] [5] [7]
  • reduce fine lines and wrinkles [2] [4] [5] [7]
  • Increase skin elasticity [2]
  • Glycation inhibitor and repair [9]
  • Scar care [2] [4] [12]
  • Sun damage protection [9]
$23.40
Based on 2 reviews.
CoQ10 (CoEnzyme Q10)

Coenzyme Q10 is a molecule naturally involved in energy metabolism in all human cells. Among its many benefits, the antioxidant properties are the most researched. This molecule can prevent oxidation damage to water-insoluble molecules, DNA mutations, collagen synthesis decrease, pigmentation, inflammation and other adverse effects associated with UV exposure and ageing. In combination with vitamin E or other antioxidants, an exceedingly strong antioxidative effect can be achieved. Furthermore, coenzyme Q10 has a unique capability to protect against infrared A radiation, which is also found in sunlight. The promotion of collagen synthesis makes this coenzyme useful in treating ageing-associated skin changes, such as wrinkle appearance. Finally, its anti-inflammatory effect is beneficial not only for UV-damaged skin, but also for wound healing support.

Key benefits of Coenzyme Q10 in skin care:

  • Sun damage protection [5] [7] [9]
  • Antioxidant [1] [3] [4] [5] [6] [7] [8]
  • Increase cellular energy production [15]
  • Stimulate collagen production [5] [8] [10] [13]
  • Lightening & brightening [10]
  • Sun damage repair [5] [7] [8]
  • Reduce fine lines & wrinkles [5] [11]
  • Wound healing support [13]
  • Anti-inflammatory [6] [10] [12] [13]
$9.00
D-Panthenol USP (Liquid)
D panthenol (Dexpanthenol) is the stable alcohol form of pantothenic acid (vitamin B5). D panthenol is well absorbed through the skin where it is rapidly converted enzymatically to pantothenic acid, a component of coenzyme A (CoA), which is important in cellular skin metabolism. Application of D panthenol is commonly used in wound management because it stimulates skin regeneration via fibroblasts proliferation and promotes wound healing. Many clinical in vivo studies provide experimental evidence of the beneficial effects of topically applied D panthenol. Studies have proved that topical usage of D panthenol enhances skin barrier repair and reduces TEWL thus being an effective moisturizer. Last but not least, the anti-inflammatory properties of D panthenol make it effective in treating various dermatologic diseases or as an adjuvant in cosmetic therapies. D panthenol has zero toxicity and it is well tolerated both topically and orally thus appropriate for human consumption and use. 

Key benefits of D-Panthenol USP in skin care:

  • Moisturizing and hydration [3]-[6]
  • Wound healing support [7] [8]
  • Anti-inflammatory [9]-[12] [15]
  • Sun damage repair [12]
  • Anti-acne [13][14]
  • Oil/sebum control [13]
$27.00
Ethyl Ascorbic Acid

Ethyl ascorbic acid is a molecule produced by modifying ascorbic acid, commonly known as vitamin C. This modification is done to increase the molecule’s stability and enhance its transport through skin, as pure vitamin C is easily degraded. In the body, the modifying group is removed and vitamin C is restored in its natural form. Thus, ethylascorbic acid retains the benefits of vitamin C, such as antioxidant activity. Furthermore, it is even more potent in reducing skin darkening after UV exposure. It even has some additional effects, not observed in pure ascorbic acid, such as promoting nerve cell growth or reducing chemotherapy damage. Finally, the slower release also ensures that no toxic effects are observed when using this vitamin C derivative.

Key benefits of Ethyl ascorbic acid in skin care:

  • Stimulate collagen production [5] [6]
  • Lightening & brightening [5] [7] [9] [9]
  • Treat hyperpigmentation [5] [7] [8] [9]
  • Sun damage protection [8] [9]
$16.10
Based on 1 reviews.
Ferulic acid (Natural)
Ferulic acid is a plant compound with numerous known health benefits. It is absorbed efficiently through skin, where it is effective as a strong antioxidant. Most often it is used in combination with vitamins C and E – this way, the individual benefits of each ingredient are strengthened, resulting in very effective UV protection. This combination even prevents DNA damage and cancer formation. The antioxidant protection is stable, remains safe from rubbing and sweating, and even resistant to natural chemical degradation, giving the product a long shelf-life. Ferulic acid alone is also beneficial, as it can restore collagen synthesis after UV exposure and thus reduce the symptoms of skin ageing. These properties make it a desirable component in sunscreens and antioxidant formulations.

NOTE: To assist you with solubility issues, we now sell Ferulic acid in three liquids: pre-dissolved solution, lipsome microemulsion, and ethosome microemulsion. Just add the liquid to your cream and mix well.
  • 6% pre-dissolved solution gives 0.5% Ferulic Acid content in final product.
  • 31% pre-dissolved solution gives 3% Ferulic Acid content in final product.
  • 51% pre-dissolved solution gives 5% Ferulic Acid content in final product.
Ferulic acid is commonly used in the Skinceuticals C+E Ferulic serum.  C E Ferulic is a revolutionary antioxidant combination that delivers advanced protection against photoaging by neutralizing free radicals, boosting collagen synthesis, and providing unmatched antioxidant protection. More protection means more youthful looking skin and better defense against environmental aging.

Key benefits of Ferulic acid in skin care:

  • Sun damage protection [4] [5]] [6] [7] [8] [9] [10]
  • Sun damage repair [9] [10] [13] [14]
  • Antioxidant [1] [3] [7] [8] [9]
  • Stimulate collagen production [13] [14]
  • Lightening & brightening [15]
  • Anti-androgenetic alopecia [3]
  • Stabilizes l ascorbic acid [5]
$8.30
Based on 1 reviews.
Fucoidan
Fucoidan is a dietary fiber extracted from brown seaweed which belongs to a class of fucose-enriched sulphated polysaccharides. Fucoidan has been used for many years in traditional Asian medicine as an anti-coagulant, anti-thrombotic, anti-cancer agent, and to modify immune responses. Topical formulations have recently been investigated for various therapeutic and cosmetic uses.  Due to anti-inflammatory and procollagen synthesis-stimulating properties, fucoidan holds promise for use healing burns, alleviating allergic reactions, and treating atopic dermatitis.  Additionally, fucoidans can increase dermal fibroblast migration and their rate of proliferation.  In several experimental approaches, fucoidan has been shown to successfully reduce the appearance of aging and to promote hair regeneration.  Fucoidan is also present in our seakelp biofermentl, but this powder fucoidan is standardized for 85% of the active ingredient.

NOTE: To assist you with solubility issues, we now also sell Fucoidan as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

Key benefits of Fucoidan in skin care:

  • Anti-inflammatory [1] [4] [8] [9] [10] [11]
  • Scar care [5] [6] [7]
  • Wound healing support [5] [6] 7]
  • Stimulate collagen production [2] [15] [16] [18]
  • Reduce fine lines and wrinkles [2, 15, 16, 18]
  • Moisturizing and hydration [15] [16] [18]
  • Increase skin elasticity [6]
  • Sun damage repair [16] [17]
  • Matrix metalloproteinases (MMP) inhibitors [15] [17]
  • Anti-androgenetic alopecia [18]
$25.10
Gamma oryzanol

Gamma-oryzanol is an ingredient produced from rice bran. It contains several related molecules, build on a ferulic acid backbone, all of which share antioxidant properties. They are particularly useful in protecting lipids, such as oils, which makes oryzanol an attractive ingredient in oil-containing preparations. Furthermore, it helps reduce skin darkening from UV exposure, as well as ageing-related skin symptoms, such as roughness and wrinkling. Since gamma-oryzanol activates sebum glands, it can be used for alleviating various conditions causing dry skin. In respect to collagen degradation, oryzanol can slow down this process even more efficiently than vitamin C, thus resulting in thicker and smoother skin. At the moment, even more possible applications of oryzanol are being investigated, such as treating hair loss or preventing damage from chemotherapy. As gamma oryzanol is oil soluble, it is an ideal active to use instead of pure ferulic acid (which is alcohol soluble).

Key benefits of Gamma oryzanol in skin care:

  • Sun damage protection [4] [9] [11]
  • Antioxidant [2] [3] [5]
  • Increase skin elasticity [9]
  • Oil/sebum control [6]
  • Moisturizing and hydration [5] [6] [9]
  • Stimulate collagen production [9]
  • Lightening & brightening [9] [11]
  • Anti-androgenetic alopecia [12]
$6.90
Ginkgo Biloba

Ginkgo biloba is a unique tree species. Its leaf extract contains a diverse variety of molecules useful in cosmetics and pharmacology. Firstly, they are potent antioxidants, and can even activate the production of enzymes that neutralize free radicals. Combined with the anti-inflammatory effects, this extract provides an effective defense against UV radiation and ageing symptoms. Dermal applications of this extract can even lead to protection of other organs. Another major application of Ginkgo biloba is moisturizing the skin, which helps to increase its elasticity and visual appearance, even reducing the amount of wrinkles. Furthermore, this extract helps to maintain the barrier function of the skin – it reduces water loss through epidermis, thus reducing skin dryness and irritation. In combination with green tea extract, Ginkgo shows even stronger benefits in these areas.

NOTE: To assist you with solubility issues, we now also sell Ginkgo Biloba extract as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

Key benefits of Ginkgo Biloba in skin care:

  • Sun damage protection [1] [6] [8] [10] [11]
  • Sun damage repair [7] [10]
  • Antioxidant [1] [6]
  • Capillary health [6] [14]
  • Increase skin elasticity [2]
  • Moisturizing & hydration [2] [3] [4]
  • Restore barrier function [2] [3] [4] [5]
  • Reduce fine lines and wrinkles [2] [4] [9]
  • Anti-inflammatory [9] [12] [13]
$9.80
Glucosamine (N-Acetyl Glucosamine)

N-acetyl glucosamine is a compound with a wealth of uses for improving skin condition. It is a known precursor to hyaluronic acid, a major component of skin structure. Hyaluronic acid is essential for hydration and n-acetyl glucosamine has been shown to increase moisture. N-acetyl glucosamine helps heal wounds, increase collagen, and reduce acne. It reduces hyperpigmentation, especially when combined with niacinamide, a member of the vitamin B3 family. It has anti-oxidant and anti-inflammatory properties which allow it to help heal and prevent sun damage. Overall, this compound can help prevent premature aging and reduce signs of aging, such as wrinkles, especially when combined with niacinamide.

Key benefits of Glucosamine in skin care:

  • Stimulate HA production [2] [3] [4] [5] [6] [7] [8] [9] 10]
  • Moisturizing and hydration [2] [5] [9] [11]
  • Treat hyperpigmentation [2] [4] [9]
  • Wound healing support [2] [11]
  • Stimulate collagen production [11]
  • Scar care [2]
  • Anti-acne [2] [6]
  • Anti-inflammatory [2] [3]
  • Anti-oxidant [2] [7]
  • Sun damage repair [1] [7]
  • Sun damage protection [7]
  • Increase skin elasticity [5] [11]
  • Reduce fine lines and wrinkles [2] [10]
  • Matrix metalloproteinases [MMP] inhibitors [7]
$6.70
Based on 1 reviews.
Grape Seed oil
Oil extracted from grape seeds is a light, pleasant-smelling oil. It is easily absorbed into the skin. The oil is rich in many different bioactive compounds. It contains high amounts of fatty acids, particularly linoleic acid, that are important for retaining moisture and skin barrier function. Grape seed oil also contains phytosterols that have anti-inflammatory effects. The oil has small amounts of polyphenols, which are known to have anti-oxidant abilities and inhibit collagen degradation. Additionally, grape seed oil has small amounts of vitamin E, which is known to act as a strong anti-oxidant. Grape seed oil applied to skin aids in wound healing, collagen production, and defends against bacteria.

 Key benefits grape seed oil in skin care:

  • Anti-oxidant [6] [7] [9] [10]
  • Sun damage protection [9] [10]
  • Moisturizing and hydration [4]
  • Stimulate collagen production [7] [10]
  • Anti-bacterial [7]
  • Wound healing support [7]
  • Matrix metalloproteinases [MMP] inhibitor [7]
BulkActives' oils are cold pressed, without the use of solvents or chemicals.
 
$8.20
Grape Seed Proanthocyanidins
Grape seed extract is a mixture of complex molecules, mostly proanthocyanidins. These molecules are very strong antioxidants, even surpassing vitamins C and E, and also show anti-inflammatory activity. Due to these properties, grape seed extract is a promising drug in combating cancer. It is capable of protecting the skin from melanoma and other cancer types, prevents already formed tumors from spreading, and can even reverse the damage in cancer-forming cells. It also reduces the cosmetical damage of UV exposure, such as increased pigmentation, thus lightening the skin. Grape seed extract is also useful in regulating sebum secretion. Finally, wound healing is strongly supported by applying this extract, as it helps tissue regeneration and provides a powerful defense against resistant bacteria.

NOTE: To assist you with solubility issues, we now also sell Grape Seed Proanthocyanidins as a liquid standardized pre-dissolved solution. Just add the liquid to your cream and mix well.
  • 11% solution gives 1% Proanthocyanidins content in final product.
  • 31% solution gives 3% Proanthocyanidins content in final product.
  • 52% solution gives 5% Proanthocyanidins content in final product.

Key benefits of Grape seed Proanthocyanidins in skin care:

  • Sun damage protection [1] [3] [5] [8] [10]
  • Sun damage repair [4] [6]
  • Antioxidant [1] [2]
  • Oil/sebum control [11] [12]
  • Lightening & brightening [11]
  • Wound healing support [14] [15]
  • Anti-inflammatory [1]
$5.70
Green Tea (90% EGCG)
Green tea has numerous benefits in almost all aspects of skin care. The main active ingredient, EGCG, is a potent antioxidant, and protects skin from UV damage. This results in reduced wrinkling, increased collagen content, smoother skin, thicker and more elastic epidermis and other visual benefits. Green tea also helps to moisturize the skin and improves the long-term barrier capabilities. Among the numerous clinical benefits are antibacterial and antifungal effects, which make green tea useful in wound care. Most important health effect is the prevention of melanoma and other types of skin cancer, resulting partly from the EGCG capability to neutralize free radicals and activate DNA repair. Since the extract also reduces inflammation and sebum secretion, it is an effective treatment against acne. Finally, green tea has also been proven to reduce hair loss and follicle death. Active ingredient in Teamine™ and ReVive™ lines.

NOTE: To assist you with solubility issues, we now also sell Green Tea EGCG in a standardized, pre-dissolved solution. Just add the liquid to your cream and mix well.
  • 11% solution gives 1% EGCG content in final product.
  • 33% solution gives 3% EGCG content in final product.
  • 54% solution gives 5% EGCG content in final product.

Key benefits of Green Tea EGCG in skin care:

  • Sun damage protection [1] [2] [3] [4] [5]
  • Sun damage repair [1] [2] [3]
  • Antioxidant [1] [2] [3] [7]
  • Capillary health [19]
  • Moisturizing & hydration [8] [9] [11]
  • Reduce fine lines and wrinkles [10] [11]
  • Wound healing support [17] [18]
  • Oil/sebum control [12]
  • Lightening & brightening [6]
  • Restore barrier function [8] [9]
  • Anti-inflammatory [1]
  • Anti-acne [12] [13]
  • Anti-bacterial [13] [14] [16]
$7.20
Based on 2 reviews.
Gynostemma (Jiaogulan)
Gynostemma pentaphyllum / Jiaogulan is a plant native to Eastern Asia. It has been used in traditional Chinese medicine for centuries, and recently it has come to the focus of many researchers due to its anti-cancer properties. The extract of this plant contains high amounts of flavonoids and gypenosides, noted for their antioxidant effects. In skin cells, this extract was shown to prevent UV-induced damage and cell death. Furthermore, it is able to reduce the levels of matrix metalloproteinases (enzymes responsible for collagen degradation), thus its applications are likely beneficial for skin collagen maintenance. It is also investigated as a promising drug against skin reddening and inflammation, observed in diseases like psoriasis.

NOTE: To assist you with solubility issues, we now also sell Gynostemma (Jiaogulan) as a liquid standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 11% solution gives 1% Gypenosides content in final product.
  • 32% solution gives 3% Gypenosides content in final product.
  • 53% solution gives 5% Gypenosides content in final product.
     

Key benefits of Gynostemma Jiaogulan in skin care:

  • Sun damage protection [4] [10]
  • sun damage repair [2] [3] [5] [6]
  • Antioxidant [2] [3] [5] [6]
  • Anti-inflammatory [2] [7]
$10.10
Hesperidin methyl chalcone
Hesperidin is a a plant flavonoid, found naturally in citrus fruits. It has numerous biological benefits, but it is poorly absorbed and transported in the body, hence a modified version, hesperidin methyl chalcone (HMC), is used in cosmetics. The best known effect of HMC is reduction of capillary permeability. This can be used to reduce dark circles and bags under the eyes or even treat varicose veins. It is also known to reduce melanin synthesis, thus lightening the skin, and it also protects skin from UV-caused damage and cell ageing. Furthermore, HMC restores the barrier function of the skin, improving hydration, regulating pH and promoting skin cell proliferation. Finally, it has an anti-inflammatory effect, and can even be used to reduce various types of pain caused by inflammation.

NOTE: To assist you with solubility issues, we now also sell Hesperidin methyl chalcone as a liquid standardized pre-dissolved solution. Just add the liquid to your cream and mix well.
  • 11% solution gives 1% Hesperidin content in final product.
  • 31% solution gives 3% Hesperidin content in final product.
  • 51% solution gives 5% Hesperidin content in final product.

Key benefits of Hesperidin methyl chalcone in skin care:

  • Sun damage protection [8] [11]
  • Capillary health [4] [5] [12]
  • Lightening & brightening [7] [8]
  • Reduce dark circles under the eyes [6]
  • Restore barrier function [1] [9] [10]
  • Anti-inflammatory [2] [5]
$10.20
Idebenone
Idebenone has qualities that make it a good choice as an antioxidant. Idebenone also promotes cellular energy production. Since it is closely related to CoQ10 it may be used as replacement for CoQ10 in many recipes. Active ingredient in Prevage, MD™ line.

Key benefits of Idebenone in skin care: 

  • antioxidant
  • cellular energy production
  • sun damage repair
$0.00
Lactic Acid -L(+) (Alpha Hydroxy Acid)
Alpha hydroxyl acids [AHAs] such as lactic acid have been used traditionally to improve the feel and complexion of the skin.  While glycolic acid has been the conventional AHA used in skin care products, lactic acid has ranked even with or outperformed lactic acid in every category and is the only AHA to maintain such success over the course of twenty-two weeks.  Lactic acid is a known exfoliant which can slough off dull skin to leave a brighter complexion.  It can also increase the synthesis of lipids and ceramides, thereby fortifying the skin barrier function and reducing water loss.  Further, lactic acid is correlated to increased hyaluronic acid and collagen synthesis, resulting in skin that is more hydrated, softer and firmer, and with fewer fine lines and wrinkles.  Topical application of lactic acid also can reduce the synthesis of melanin and decrease the appearance of hyperpigmentation or age spots.  Incorporation of lactic acid in skin care products can lighten and brighten skin while improving dermal health and reducing the appearance of photoaging.

Key benefits of Lactic acid in skin care:

  • Capillary health [10], [12]
  • Increase skin elasticity [1] [2] [8] [9]
  • Lightening & brightening [1] [2] [4]  [9]  [11]
  • Moisturizing and hydration [6] [7]
  • Reduce fine lines and wrinkles [1] [2] [8] [9]
  • Restoring barrier function [5] [6] [7]
  • Stimulate collagen production [9]
  • Stimulate HA production [8] [9]
  • Sun damage repair [1] [2] [8] [9]
  • Treat hyperpigmentation [2] [9]
$5.10
Lemon Peel Bioferment
Our lemon peel bioferment uses fermentation as a method to extract valuable chemicals from the peel, releasing them to be used by our skin.  Lemon peel bioferment  is an antioxidant, inhibitor of melanin synthesis, and bactericide. Tyrosinase inhibition is similar to that obtained with hydroquinone. Lemon peel extract has anti-tyrosinase activity as high as hydroquinone.

Key benefits of Lemon Bioferment in skin care: 

  • antioxidant
  • skin lightening and brightening
  • inhibitor of melanin synthesis
  • inhibits tyrosinase
  • increased luminosity
  • bactericide
  • non sensitizing
  • not cytotoxic
$21.00
Niacinamide (Vitamin B3)
Niacinamide, also known as nicotinamide, is a water soluble form of vitamin B3. Vitamin B3 is essential for maintaining skin health. Niacinamide increases production of important skin structural components such as collagen, ceramide, and keratin. This helps increase moisture and strengthen skin. Niacinamide is known to decrease hyperpigmentation, effectively lightening and brightening skin, especially when used together with n-acetyl glucosamine, a hyaluronic acid precursor. It reduces wrinkles and again, this effect is better with n-acetyl glucosamine. Niacinamide also effectively helps reduce acne and heal wounds. It has anti-oxidant and anti-inflammatory properties. Overall, niacinamide is a compound with many different uses that can increase overall skin health.

Key benefits of Niacinamide in skin care:

  • Treat hyperpigmentation [3] [7] [8]
  • Lightening and brightening [3] [7] [8]
  • Reduce fine lines and wrinkles [9]
  • Anti-inflammatory [5] [6] [8]
  • Anti-oxidant [10] [13]
  • Anti-acne [1] [5] [11]
  • Moisturizing and hydration [2] [5] [12]
  • Restore barrier function [2] [5] [12]
  • Wound healing support [5] [6]
  • Increase skin elasticity [5] [9]
  • Oil/sebum control [2]
  • Pore refinement [2]
  • Sun damage repair [13]
  • Sun damage protection [10]
  • Stimulate collagen production [5]
  • Stimulate HA production [9]
$5.10
Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 Liposome Emulsion
The Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 peptides liposome emulsion contains the peptides pal-ghk and pal-gqp acting in synergy to repair the cutaneous damages of age. By activating the skin’s natural production of collagen, elastin and hyaluronic acid, the peptides work to reduce wrinkles and other signs of aging. Collagen, made up of long strands of amino acids, is really the main building block of skin, giving the skin its smooth, and youthful appearance. As we age, collagen is lost, and this gives way to aged, wrinkled looking skin. When the long strands of amino acids in collagen are broken down they create small chains commonly referred to as peptides. The presence of these peptides signal to the skin that it has lost collagen and the production of more is necessary. The peptides Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 work to mimic the appearance of this broken down collagen, causing your skin to react by producing more collagen, as well as elastin (responsible for the skin’s elasticity, and  hyaluronic acid (which plumps up the skin and gives it that healthy, full look).

Key benefits of the peptides Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 liposome emulsion in skin care:

  • reduce fine lines and wrinkles
  • stimulate HA production
  • glycation inhibitor and repair
  • increase skin elasticity
  • moisturizing and hydration
  • stimulate collagen production
  • sun damage repair

BulkActives Peptide Liposome Emulsion

  • Palmitoyl oligopeptide (PAL GHK) 260ppm  
  • Palmitoyl tetrapeptide-7 ppm (PAL GQPR) 140ppm
  • Twice the strength of Matrixyl 3000
$19.95
Based on 8 reviews.
Pine Bark (95% Proanthocyanidins)
Pine bark extract is a mixture of organic molecules with various health and cosmetical benefits. The proanthocyanidins found in this mixture have strong antioxidant properties. They are also known to reduce inflammation and redness (erythema) resulting from it. Combined, these effects make pine bark extract a potent defense against UV radiation, and it can even prevent various types of skin cancer. Furthermore, toxic effects of metal ions can be alleviated by applying this extract. In postmenopausal women, this extract has been proven to reduce wrinkles and improve skin hydration. Additionally, the molecules found in pine bark maintain good blood vessel health – the extract can alleviate hypertension and help capillaries recover after injuries, making it useful in wound care.

NOTE: To assist you with solubility issues, we now also sell Pine Bark Proanthocyanidins as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.
  • 11% solution gives 1% Proanthocyanidins content in final product.
  • 32% solution gives 3% Proanthocyanidins content in final product.
  • 53% solution gives 5% Proanthocyanidins content in final product.

Key benefits of Pine bark Proanthocyanidins in skin care:
  • Sun damage protection [3], [6], [11]
  • Antioxidant [1], [2]
  • Increase skin elasticity [9]
  • Moisturizing and hydration [9]
  • Lightening & brightening [11]
  • Wound healing support [12], [13]
  • Capillary health [11]
  • Anti-inflammatory [3]–[5]
  • Water soluble!
$6.10
Pomegranate (40% Ellagic)
Pomegranates have been used in medicine since ancient times. The extract of this plant contains many compounds acting synergistically to produce strong antioxidant and anti-inflammatory effects. It also helps maintain collagen levels, both by promoting its synthesis and inhibiting collagen-degrading enzymes. Due to these properties, pomegranate extract has a range of benefits in UV protection – it can be used both to prevent and to reduce sunlight damage (photoageing) after exposure. Furthermore, it is an effective skin whitening agent, used to treat melasma and other hyperpigmentation problems. Finally, faster wound healing is observed when using this extract. Combined with antibacterial, antifungal, anti-inflammatory properties and the ability to increase collagen synthesis, this makes pomegranate extract beneficial in many aspects of wound care.

NOTE: To assist you with solubility issues, we now also sell Pomegranate Extract as a standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 25% solution gives 1% Ellagic Acid content in final product.
  • 75% solution gives 3% Ellagic Acid content in final product.
  • 13% solution gives 1% Polyphenols content in final product.
  • 39% solution gives 3% Polyphenols content in final product.
  • 65% solution gives 5% Polyphenols content in final product.

 Key benefits of Pomegranate extract in skin care:

  • Sun damage protection [4], [7], [8]
  • Sun damage repair [7]–[9]
  • Antioxidant [1]–[4]
  • Glycation inhibitor and repair [3]
  • Anti-bacterial [2], [16]
  • Lightening and brightening [6], [10]–[12]
  • Matrix metalloproteinase (MMP) inhibitors [8], [9]
  • Stimulate collagen production [9]
  • Treat hyperpigmentation [10]–[12]
  • Wound healing support [13]–[16]
  • Anti-inflammatory [6], [8], [15]
$6.30
Pomegranate Seed Oil
Seed oil extracted from the pomegranate fruit contains high amounts of fatty acids, particularly punicic acid. Pomegranate seed oil is the only seed oil with punicic acid, making this a unique extract. Punicic seed is known to have anti-oxidant and anti-inflammatory effects. Present in smaller amounts in this seed oil are estrogen-like compounds which have potential to alleviate menopausal symptoms. Studies with pomegranate seed oil show it acts as a powerful antioxidant by decreasing reactive oxygen species that harm the body. It also protects against sun damage, and can repair sun-related damage to the skin by increasing skin thickness and barrier cell replication. This effect also aids in wound healing and can reduce skin thinning with age.  

Key benefits of Pomegranate Seed Oil in skin care:

  • anti-oxidant [1][3][5][6][7][8][9][10][12]
  • anti-inflammatory [3][7][8][10)
  • sun damage repair [1][6][2]
  • sun damage protection [1][9]
  • wound healing support [2]
  • restore barrier function [2][11]
  • natural phyto estrogens [7]
  • moisturizing and hydration
BulkActives' oils are cold pressed, without the use of solvents or chemicals.

 
$17.80
Quercetin
Quercetin is a molecule belonging to a class of complex organic compounds called flavonoids. Quercetin is produced by many plants, notably onions. The most important effect of this molecule is neutralizing free radicals. Quercetin can achieve this directly, due to its antioxidative properties, or by binding iron ions, which play a strong part in the accumulation of free radicals. Therefore, quercetin is an important component in UV-protective cosmeceuticals. It can also reduce the inflammation, darkening and synthesis of collagen-degrading enzymes, caused by UV exposure. Furthermore, quercetin has benefits for wound care, as it improves both healing of new wounds and subsequent scar formation. It even has a positive effect on the lifespan of cells, slowing down processes of cell ageing.

NOTE: To assist you with solubility issues, we now also sell Quercetin as two liquids: standardized pre-dissolved solution and standardized ethosome microemulsion. Just add the liquid to your cream and mix well.
  • 11% solution gives 1% Quercetin content in final product.
  • 31% solution gives 3% Quercetin content in final product.
  • 51% solution gives 5% Quercetin content in final product.

Key benefits of Quercetin in skin care:

  • Sun damage protection [3], [5]–[7]
  • Sun damage repair [3], [5]
  • Lightening & brightening [8]
  • Treat hyperpigmentation [8]
  • Anti-inflammatory [6], [7]
  • Antioxidant [1]–[4], [14]
  • Scar care [11]–[13]
  • Wound healing support [9], [10]
$12.90
Resveratrol (Trans-resveratrol 98%)
Resveratrol is a compound found in grapes and many other plants. It is currently investigated in many skincare applications. Resveratrol protects cells from oxidative stress – it is an antioxidant itself, and activates the synthesis of other such compounds. It also regulates inflammatory responses and even aids the distribution of cosmetical sunscreens, thus helping to prevent UV damage to the skin. Similarities in structure allow resveratrol to replace estrogen in post-menopausal women, helping to reduce collagen loss and reduce skin ageing symptoms. Additionally, it counters photoageing by inhibiting melanin synthesis, resulting in lighter skin and less pigmented spots. Even acne can be alleviated by applying resveratrol, as it has antibacterial properties and controls sebaceous cell growth. Finally, it is a promising agent in melanoma prevention, able to delay the emergence and reduce the size of skin tumors.

NOTE: To assist you with solubility issues, we now also sell Resveratrol in a standardized  pre-dissolved solution. Just add the liquid to your cream and mix well.

Key benefits of Resveratrol in skin care:

  • Anti-acne [15]–[17]
  • Anti-bacterial [16]
  • Antioxidant [1]–[4]
  • Anti-inflammatory [1], [4], [8], [9]
  • Sun damage protection [1], [6]–[8], [11]
  • Increase skin elasticity [14]
  • Lightening & brightening [10]–[13]
  • Natural phytoestrogens [1], [8], [9]
$7.10
Rosehip Oil Organic
Oil extracted from the fruit of rose plants [known as rosehips] contains compounds with many therapeutic uses. Rosehip oil is high in fatty acids, including linoleic, oleic, and alpha-linolenic acids. Fatty acids are known to moisturize and restore skin barrier function. The oil also contains trans-retinoic acid, a precursor of vitamin A, which is known to help restore skin tissue. The oil is widely known to reduce the appearance of scars by reducing their profile, decreasing hyperpigmentation, and increasing skin elasticity. It can also reduce the effects of premature aging and sun damage. Rosehip oil has been shown to have anti-inflammatory properties.

Key benefits of Rosehip oil in skin care:

  • Anti-inflammatory [1, 2, 6, 10, 11]
  • Scar care [3, 4, 5, 9, 14]
  • Restore barrier function [3, 4]
  • Sun damage repair [4, 5]
  • Treat hyperpigmentation [5, 9]
  • Reduce fine lines and wrinkles [5]
  • Wrinkle relaxer [5]
  • Increase skin elasticity [5]
  • stimulate collagen production [10][14]
  • Moisturizing and hydration [4]
BulkActives' oils are cold pressed, without the use of solvents or chemicals.


 
$24.60
Safflower Seed Oil
Safflower is a plant mainly grown for the oil in its seeds. This oil contains the highest amount [70%] of linoleic oil of any plant oil. Linoleic acid is known to benefit the skin in many ways. It moisturizes and hydrates the skin, correcting fatty acid deficiencies that cause dry, itchy skin. Due to the high amount of linoleic acid, safflower oil can be used to heal wounds, burns, and acne. Safflower oil also contains oleic acid [15%]. Oleic and linoleic acids combined can be used to reduce the appearance of scars and increase collagen production.

Key benefits of Safflower seed oil:

  • Moisturizing and hydration [1, 3, 5, 8, 9]
  • restore barrier function [1, 3, 5, 8, 9]
  • Wound healing support [1, 2, 5]
  • Sun damage prevention [10]
  • Sun damage repair [8]
  • Anti-acne [8]
  • Anti-inflammatory [4]
  • Stimulate collagen production [6]
  • Scar care [2]
BulkActives' oils are cold pressed, without the use of solvents or chemicals.

 
$8.80
Salicylic Acid (Beta Hydroxy Acid)

Salicylic acid is a hydroxyl acid compound originally derived from willow tree bark. It has many useful effects on skin, the most prominent being its use as an anti-acne treatment. It penetrates deep into pores, removing trapped oil that can cause blemishes. Salicylic acid is a keratolytic compound, meaning it exfoliates the skin and sloughs off dead skin cells, leaving smooth skin. This makes it useful for treating scaly skin, as well as calluses and warts. It also has anti-inflammatory and anti-bacterial properties. Salicylic acid has been shown to influence photodamage by reducing hyperpigmentation and providing protection against UV exposure.

NOTE: To assist you with solubility issues, we now also sell Salicylic Acid (Beta Hydroxy Acid) as a pre-dissolved solution. Just add the liquid to your cream and mix well.

  • 6.7% solution gives 1% Salicylic acid content in final product.
  • 13.3% solution gives 2% Salicylic acid content in final product.
  • 20% solution gives 3% Salicylic acid content in final product.
  • 26.7% solution gives 4% Salicylic acid content in final product.
  • 33.3% solution gives 5% Salicylic acid content in final product.
     

Key benefits of Salicylic acid in skin care:

  • Anti-acne [2] [4] [6] [9] [10]
  • Anti blackheads [2] [4]
  • Anti-inflammatory [1] [3] [4] [5]
  • Exfoliator [2] [6] [10]
  • Oil/sebum control [2] [4]
  • Pore refinement [2] [4]
  • Increase skin cell turnover [2] [5] [6] [10]
  • Treat hyperpigmentation [2] [7]
  • Reduce fine lines and wrinkles [2] [7]
  • Anti-bacterial [8] [10]
  • Sun damage protection [8]
  • Sun damage repair [7] [8]
$4.10
Based on 1 reviews.
Sclerotium Gum
Sclerotium gum is an active ingredient obtained through fermentation from hardened fungal masses of various types of fungi. The most common source is a parasitic fungus named Sclerotium rolfsii.  Due to its efficiency as a thickening agent, emulsifier and stabilizer, sclerotium gum is used in numerous applications in the industrial, food and pharmaceutical fields. Recent research showed that sclerotium gum is a compound perfectly suitable for topical delivery of pharmaceuticals and natural active ingredients. Besides providing the right viscosity and stability of the topical preparation, the gum also has multiple benefits for the skin. Sclerotium gum is high in polysaccharides, especially beta glucans, namely scleroglucan, and has multiple benefits for the skin: it protects the lipid barrier, prevents water loss, increases moisturization, protects and repair damaged skin, enhances the local immune response and increases collagen production and deposits.

Key benefits of Sclerotium Gum in skin care:

  • moisturizing and hydration [9][12][13]
  • anti-inflammatory [6] [10]
  • wound healing support [6] [10]
  • sun damage protection [10]
  • sun damage repair [10]
  • stimulate collagen production[11]
  • Anti-bacterial [11]
  • Antioxidant [10]
  • Restore barrier function [9][12][13]
 
  • Emulsion stabilizer
  • Improves flow of emulsions
  • Wide pH tolerance :: 5 to 12
  • Offers a nice feel to products
  • Viscosity not affected by high heat
  • Stable in extreme physical and chemical conditions
  • Creates smooth flowing gels / serums
  • Improves natural moisture levels in skin and hair
  • Gels the water phase for enhanced viscosity without stiffness
  • Outstanding suspending ability
  • Alternative to carbopol and Gelmaker Ultra
  • Moisturizer
$11.00
Silymarin
Silymarin is a flavonolignans complex that can be only found in the seeds of Milk thistle (Silybum marianum), a member of the Compositae family native to the Mediterranean, now widespread all over the world. It consists of a mixture of three bioflavonoids found in the fruit, seeds, and leaves of the milk thistle plant: silibinin, silidianin, and silicristin and a flavonoid – taxifolin. Silymarin has strong antioxidant properties (fold times vitamin E) several studies proving its free radical and ROS scavenging effects thus suitable especially for the prevention and treatment in several forms of epithelial cancer. Another area of application for the antioxidant properties of silymarin is topical skin care with results in UV protection, UV effects attenuation, Rosacea, Melasma, acne and other skin pigmentation conditions. The potent anti-inflammatory mechanisms of silymarin are used for wound management, with benefits especially for the patients with healing impairing diseases. Silymarin has very low toxicity and it is well tolerated thus appropriate for human consumption and use.

NOTE: To assist you with solubility issues, we now also sell Silymarin as two liquids: standardized pre-dissolved solution and standardized ethosome microemulsion. Just add the liquid to your cream and mix well.
  • 13% solution gives 1% Silymarin content in final product.
  • 38% solution gives 3% Silymarin content in final product.
  • 63% solution gives 5% Silymarin content in final product.
  • 34% solution gives 1%Silybin content in final product.
  • 67% solution gives 2% Silybin content in final product.

 
Key benefits of Silymarin in skin care:

  • Antioxidant [4] [5] [6] [7] [8]
  • Sun damage protection [10] [11]
  • Sun damage repair [12] [13]
  • Anti-acne [10] [15]  [17]
  • Anti-inflammatory [19] [20]
  • Lightening and brightening [16]
  • Treat hyperpigmentation [16]
  • Reduce Rosacea [10] [15]
$6.80
Sodium Ascorbyl Phosphate (SAP)
Vitamin C, or ascorbic acid, is one of nature’s most powerful antioxidants.As the natural aging process and environmental hazards increase the amount of free radicals in the skin, ascorbic acid and its derivatives can effectively neutralize these damaging agents and prevent further damage.Ascorbic acid has been shown to increase the synthesis of collagen in the skin to reduce the appearance of wrinkles and to block the melanin synthesis pathway, reducing age spots and lightening skin.Unfortunately, ascorbic acid is not stable in aqueous solutions and is quickly degraded.The hydrophilic ascorbic acid derivative sodium ascorbyl phosphate is significantly more shelf-stable in solutions and, as it is converted to ascorbic acid in skin, retains all of the skin-benefitting aspects of vitamin C.Therefore sodium ascorbyl phosphate is the ideal choice for anti-aging emulsion creams.

Key benefits of Sodium Ascorbyl Phosphate in skin care:

  • Anti-acne [7]  [8]
  • Antioxidant [3] [4] [6] [9] [10]
  • Increase skin elasticity [1] [4]
  • Reduce fine lines and wrinkles [1] [4]
  • Stimulate collagen production [1] [4]
  • Sun damage protection [9] [10]
  • Sun damage repair [9] [10]
  • Lightening and brightening [12]
  • Treat hyperpigmentation [12]
$10.30
Soy Isoflavones
Soy isoflavones are comparatively new in regards to cosmetic use, however, studies show they have multiple skin-benefitting properties.Isoflavones are structurally similar to estrogens and can activate estrogen signaling pathways, including collagen synthesis, to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and increase tissue hydration.Additionally isoflavones are powerful antioxidants that can halt and reverse the appearance of aging due to free radicals caused by sunlight and other environmental hazards.As such, soy isoflavones are useful in reducing redness of the skin and decreasing the appearance of dark spots.These properties make soy isoflavones ideal for use in anti-aging, moisturizing, and skin protecting creams.

Key benefits of Soy isoflavones on skin care:

  • Anti-inflammatory [6, 11, 12]
  • Antioxidant [3, 6]
  • Increase skin elasticity [1, 4, 5, 15]
  • Matrix metalloproteinase [MMP] inhibitors [9]
  • Moisturizing and hydration [5, 15]
  • Natural phytoestrogens [3, 15]
  • Reduce fine lines and wrinkles [1, 4, 5, 15]
  • Stimulate collagen production [1, 4, 5, 15]
  • Sun damage protection [3, 6, 11, 12, 14]
  • Sun damage repair [3, 6, 11, 12, 14]
  • Treat hyperpigmentation [3]
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