Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
Reviews
This is the best product I have ever used on my skin and I tried a LOT of expansive brands. It helps with redness and overall skin tone. Please do not ever stop making this stuff... ...»
Helena
I' m not sure about this: "11% solution gives 1% EGCG content in final product." What is the weight of final product? .. ...»
Vesna Hanich
It is true, this product does leave the skin silky smooth! I can highly recommend using it in your masks... ...»
Mati Fuller
Just recently ordered this and LOVE! Green Tea EGCG truly is one of the most fantastic skincare actives out there. Very difficult to find good quality product (90%) and even harder to actually solubilize it! Love that it comes in pre-dissolved solution. I enjoy adding it at 1% (so 11% sol) to my serum formulations containing Niacinamide 5% + NAG 3%. Excellent for oily acne prone skin. *Only gripe... because the Pre-Dissolved Solution is SO heavy in propanediol (10 parts Propanediol for 1 part E.. ...»
Victor
The Pre-dissolved solution is excellent. Ferulic Acid is an amazing skincare ingredient (potent antioxidant, protects other sensitive antioxidants from light degradation, UV protection) but is absolutely ineffective if it isn't solubilized correctly. Makes adding to any Serum Base or w/o emulsion easy. Love using it (at 6%; so active 0.5%) with the Resveratrol Fluid (10%; active 1%) and Green Tea Extr for potent nighttime brightening treatment... ...»
James
The best, most potent and most stable form of Vitamin C. Makes quite a difference to the appearance of mature, photo-damaged skin - don't expect results over night but with consistent use your skin will look more even and radiant!.. ...»
Judy
This ingredient has done more for my skin than anything else I've ever used. I put it into a spray facial toner and use it morning and night. I noticed the effects immediately, they were that dramatic. I will use this forever, no question... ...»
Marie
Love the fine powder ascorbic acid. I use it in a recipe for skin care along with hyaluronic acid. I'm 65 years old and absolutely no one believes it 'cause I've been doing this for years... ...»
Kathy
Purchased this some time ago from BulkActives and here to buy some more! Great stuff!!!!.. ...»
Kathy
I've been using Bulkactives green tea EGCG for four years. No complaints, it blends nicely my DIY anti-aging cream. I can feel a bit of toning and definitely notice the anti-inflammatory effects on my skin. Two observations that keep the rating 4 stars instead of 5: (1) A package of green tea contains significantly less weight/volume than the package of grape seed extract that I order from bulkactives. The two are combined in equal amounts in the anti-aging cream, so I find myself running o.. ...»
Theresa Andrews
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Near The End

BulkActives has been in business since 2005, we might have disappeared from google search results, 

but we're still hanging on, just, mainly thanks to the support of some loyal customers.

However, like many, COVID hit us hard, and we're having a lot of trouble recovering.

Right now, we have not restocked many powders, however, are looking at continuing with selling only our flagship products:

seakelp and pre-dissolved powders, and some of the essentials.

lightening and brightening

Lightening and brightening in skin care

Skin and skin color

Skin is the largest organ of the human body performing several vital functions such as physical and chemical protection [1], sensation, thermoregulation, excretion and storage. Skin structures protect not only the outer body but also the internal organs. The skin major layers are epidermis – the external layer mainly composed out of keratinocytes that produce keratin and melanocytes that produce melanin – the skin pigment, dermis – mainly composed of collagen and elastin acting as connective tissue and the skin supporting tissue called hypodermis – a fat cells and blood vessel base. Epidermis, the outermost skin layer, plays the most important role in the barrier function, acting against physical and chemical aggressions [2] [3].

The actual skin color of human skin which may vary from dark brown to light pink is influenced by several substances, but the single most important substance is the pigment melanin. Melanin is produced by melanocytes located in the epidermis and has the fundamental role in pigmenting keratinocytes, being the main determinant of the skin color [4]. There is a proved direct proportionality causal correlation between skin pigmentation and the geographic distribution of UV radiation meaning that in the areas where the sun exposure is stronger and prolonged the indigenous population has darker pigmented skin. This enforces the importance of melanin and implicitly skin color in UVR protection [5].


Melanin pigment production

Melanin pigment production is called melanogenesis. It takes place in the melanocytes by a cytoplasm organelle called melanosome [6]. Melanin production has four phases directly correlated with the four stages of development of melanosomes that starts with an spherical non-pigmented shape and evolve into full concentration of melanin that is distributed along microtubes and further on via melanocytes’s dendridic structures to keratinocytes that will pigment accordingly.  An interesting fact is that both fair and dark skin contains an approximately equal number of melanocytes, thus a similar theoretical capacity of producing melanin. What differs is the size of melanosomes and the degree of pigmentation as well as the production rate (all higher in darker skin). Skin pigmentation and implicitly skin colors and tones are a result of a mixture of the two types of melanin eumelanin – more frequent in darker skin and pheomelanin – more frequent in the lighter skin [7].  

Skin pigmentation

As any living mechanism, skin pigmentation is also a process that sometimes presents anomalies that can be temporal or permanent. Changes in the normal melanin production with either local or generalized manifestations are generally called skin pigmenting disorders. There are several classifications of skin pigmentation disorders, based on various criteria. The most common classification is based on the hypo (lowered) or hyper (increased) pigmentation of the diseased skin as presented in table 1 – an enumeration of the most common skin pigmentation disorders [8].

Hyperpigmentation

Hypopigmentation

  • Postinflammatory hyperpigmentation (post: acne, psoriasis, atopic and contact dermatitis, lichen planus, trauma, drugs)

  • Melasma

  • Solar lentigines

  • Ephelides (freckles)

  • Café-au-lait macules

  • Nevi

  • Melanoma and precursors

  • Vitiligo

  • Pytiriasis alba

  • Tinea versicolor

  • Postinflammatory hypopigmentation

  • Albinism (congenital)

  • Piebaldism (congenital)

  • Tuberous sclerosis (congenital)

  • Hypomelanosis of Ito (congenital)

Table 1 – most common skin pigmentation disorders [8]

While not much can be done topically when it comes to congenital skin pigmenting disorders no matter if they are primary or secondary to the disease in the past years considerable progress has been made in the local treatment of pigmentary disorders, especially in hyperpigmentation.

Topical solutions for skin pigmentation

Causes for skin pigmentation imbalance are multiple and heterogeneous, from postinflammatory, UVR exposure, pregnancy to aging thus topical treatment is based on several mechanisms that counteract against the multiple array of factors. The substances that have proved efficiency in treating pigmentary disorders are generically called lightening and brightening agents. Based on their active principles the topical solutions against acquired hyper and hypo pigmenting can be categorized in 4 major groups, as presented in table 2 [7] [9] [10]

Group

Agents

Tyrosinase inhibitors
Inhibit tyrosinase secretion of the melanocytes thus decreasing the rate of melatonin production.

  • Flavonoids
  • Licorice Extract
  • Gamma oryzanol
  • Pomegranate
     

 

Melanosome transfer inhibitors
Interfere with the mature melanocites transfer to the keratinocytes thus lowering the pigment transfer rate.
 

  • Niacinamide
  • Soy

Antioxidants               
Reinstate epidermal antioxidants balances thus regulating melanin production (especially in UVR and aged related hyperpigmentation)

  • L ascorbic acid (vitamin C)
  • Vitamin C derivatives
  • Vitamin E
  • Green tea
  • Pycogenlol (Pinebark)
  • Silymarin
  • Alpha Lipoic Acid

Epidermal turnover accelerants and desquamators
Clinically show activity in inhibiting and/or regulating melatonin production

  • Alpha and Beta Hydroxy Acids
  • Linoleic acid
  • Pyruvic acid

Table 2 – classification of the most common skin lightening and brightening agents [7]

With very few to none side effects even in high quantities natural occurring agents are preferred for topical treatment of pigmentation disorders.

In the tyrosine inhibitors group flavonoids for example are naturally occurring in various plants and fruits, the more red-orange-yellow spectrum colored, the higher the flavonoid concentration. Flavonoids may have hypopigmenting capabilities by directly inhibiting tyrosinase activity at distal portions of the melanogenic pathway.Flavonoids inhibit enzymes due to their abilities to chelate copper at the active site and may also have ROS scavenging properties  For example, hesperidin – a plant flavonoid – is proved to have anti-melanin and anti-yellowing effects [11] [12]. Another flavonoid, quercetin is also effective against age-related hyperpigmentation [13]. Isoflavones, important flavonoid components are renowned for their multiple benefic properties can be found in several extracts such as pomegranate, white willow, grapes seed, soy and many others.  Licorice extract (Dipotassium glycyrrhizinate) is also known to be effective in inhibiting the tyrosine mechanism [7]. ferulic acid and Gamma oryzanol were shown to have dual inhibitory activities for cellular melanogenesis by inhibiting tyrosinase enzyme activity and reducing MITF and target genes in the PKA-dependent pathway [31]. Ellagic acid,  is a natural polyphenol that is widely found in fruits and vegetables including berries, green tea and pomegranate with strong antioxidative properties and tyrosinase inhibition. The extract of the rinds of pomegranate contains 40% ellagic acid and showed inhibitory activity against mushroom tyrosinase in vitro. The mechanism of action of ellagic acid may due to chelating copper at the active site of tyrosinase to reduce its activity and inhibition of proliferation of melanocytes and melanin synthesis. In addition, the antioxidative and ROS-scavenging activities of EA may contribute to its skin-whitening effect.

Niacinamide (Vitamin B3) is the champion in the melanosome transfer ingibitors cayegory, several studies showing its effect on reducing hyperpigmentation[15]. In clinical studies, topical 4% niacinamide inhibits pigmentation [15] [16]. A greater effect was seen when combined with 2% n-acetyl glucosamine, a hyaluronic acid precursor [14] [16].

In the Antioxidants category the absolute star is Vitamin C (ascorbic acid) since it and its derivative actives have been used for ages, long before science proved their efficiency. Both in vitro and in vivo trials proved that ascorbic acid plays an important role especially in sun exposure induced hyperpigmentation [17][18][19]. Vitamin E is also an effective antioxidant and sun damage repair agent and implicitly in UVR related pigmentation. Other antioxidants such as silymarin [20], ferulic acid [21], grape seeds extracts [22], green tea extracts [23], pine bark extracts [24], pomegranate extracts [25] [26] act as effective anti-pigmenting agents.

In the Epidermal turnover accelerants and desquamator category one the most remarkable agents are lactic acid an alpha hydroxy acids, which were proven as an efficient anti-pigmenting agent in several studies in which topical application decreased hyperpigmentation or the appearance of age spots [27] [28].  At low concentrations AHAs promotes exfoliation by decreasing corneocyte cohesion and stimulating new growth in the basal layer, while at higher concentrations AHAs promote epidermolysis and dispersed basal layer melanin.The accelerated desquamation of the stratum corneum by AHAs is complemented by a direct inhibition of tyrosinase. Resveratrol is another lightening and brightening agent efficient in topical ointments [29][30][31].

Fatty acids such as Linoleic acid reduce the activity of tyrosinase in melanocytes and selectively target tyrosinase by altering the tyrosinase protein content in hyperactive melanocytes. Linoleic acid also influences skin pigmentation by stimulating epidermal turnover and increased desquamation of melanin pigment from the epidermis.

Skin care actives involved in skin lightening and brightening processes:

  • hesperidin [11] [12]
  • quercetin [13]
  • licorice extract [7]
  • niacinamide (Vitamin B3) [14] [15] [16]
  • ascorbic acid (Vitamin C and its delivatives) [17] [18] [19]
  • silymarin [20]
  • Gamma oryzanol [31]
  • ferulic acid [21]
  • grape seeds extract [22]
  • green tea extract [23]
  • pine bark extract [24]
  • pomegranate extracts [25] [26]
  • lactic acid [27] [28]
  • resveratrol [29] [30] [31]
References:
[1]  E. Proksch, J.M. Brandner, J.M. Jensen, "The skin: an indispensable barrier" Experimental  Dermatology, 17 (12): pp:1063–1072, 2008
[2]  K.C. Madison, “Barrier function of the skin: “la raison d’etre of the epidermis””, Journal of Investigative  Dermatology, 121 (2), pp: 231–241, 2003
[3]  P. F. Millington,R. Wilkinson, “Skin”,  Cambridge University Press, pp:1-18, 1983
[4]  N.G. Jablonski, “Skin: a Natural History”, Berkeley: University of California Press, 2006
[5]  A.R. Webb,"Who, what, where, and when: influences on cutaneous vitamin D synthesis", Progress in Biophysics and Molecular Biology 92 (1): 17–25, 2006
[6]  N. Agar, A.R. Young, "Melanogenesis: a photoprotective response to DNA damage?", Mutation research, 571,pp: 121–132, 2003
[7]  L. Bauman, “Cosmetic Dermatology – Principles and Pactice”, second edition, ISBN: 978-0-07-164128-9
[8]  S. PLENSDORF, J. MARTINEZ, “Common pigmentation disorders”, American Family Physician, 79, pp 109-116, 2009
[9]  E. Dupont, H.Gomez, C.Leveille,E. Loing, D.Bilodeau, “A whiter shade of pale”, Personal Care Magazine, pp: 25-30, January 2011
[10]  C.Burgess,Cosmetic Dermatology, ISBN 3-540-23064-5 Springer Berlin Heidelberg New York, 2005
[11]   W. Zhu and J. Gao, “The Use of Botanical Extracts as Topical Skin-Lightening Agents for the Improvement of Skin Pigmentation Disorders,” J. Investig. Dermatol. Symp. Proc., 13, pp: 20–24, 2008
[12]  Y.-B. Huang, K.-F. Lee, C.-T. Huang, Y.-H. Tsai, and P.-C. Wu, “The effect of component of cream for topical delivery of hesperetin,” Chem. Pharm. Bull. (Tokyo), 58, pp: 611–614, 2010
[13]  N. Chondrogianni, S. Kapeta, I. Chinou, K. Vassilatou, I. Papassideri, and E. S. Gonos, “Anti-ageing and rejuvenating effects of quercetin,” Exp. Gerontol., 45, pp: 763–771, Oct. 2010
[14]  D.L. Bissett, L.R. Robinson, P.S. Raleigh, K. Miyamoto, T. Hakozaki, J. Li, and G.R. Kelm, “Reduction  in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine,” Journal of Cosmetic Dermatology, 6, pp. 20–26, 2007
[15]  B. Kimball, J.R. Kaczvinsky, J. Li, L.R. Robinson, P.J. Matts, C.A. Berge, K. Miyamoto, and D.L. Bissett, “Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double- blind, vehicle-controlled trial,” British Journal of Dermatology, 162, pp:435–441, 2010
[16]  J. Navarrete-Solis, J.P. Castanedo-Cazares, B. Torres-Alvarez, C. Oros-Ovalle, C. Fuentes-Ahumada, F.J. Gonzalez, J.D. Martınez-Ramırez, and B. Moncada, “A Double-Blind, Randomized Clinical Trial of   Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma”, Dermatology Research and Practice, pp:1-5, 2011.
[17]  H. Ando, H. Kondoh, M. Ichihashi, and V. J. Hearing, “Approaches to identify inhibitors of melanin biosynthesis via the quality control of tyrosinase,” J. Invest. Dermatol., 127, pp: 751–761, 2007.
[18]  S. Kim, S. Y. Oh, and S. H. Lee, “Comparative Study of Glycolic Acid Peeling vs. Vitamin C-iontophoresis in Melasma,” Korean J. Dermatol., 39, pp: 1356–1363, 2001
[19]  S.-W. Hwang, D.-J. Oh, D. Lee, J.-W. Kim, and S.-W. Park, “Clinical efficacy of 25% L-ascorbic acid (C’ensil) in the treatment of melasma,” J. Cutan. Med. Surg., 13, pp: 74–81, 2009
[20]  Tagreed Altaei, “The treatment of melasma by silymarin cream”, BMC Dermatology 201, pp 12-18, 2012
[21]  M. Ichihashi, Y. Funasaka, A. Ohashi, A. Chacraborty, N. U. Ahmed, M. Ueda, and T. Osawa, “The inhibitory effect of DL-alpha-tocopheryl ferulate in lecithin on melanogenesis,” Anticancer Res., 19, pp: 3769–3774, 1999
[22]  A. Sharif, N. Akhtar, M. S. Khan, A. Menaa, B. Menaa, B. A. Khan, and F. Menaa, “Formulation and evaluation on human skin of a water-in-oil emulsion containing Muscat hamburg black grape seed extract,” Int. J. Cosmet. Sci., 2014
[23]  Y.-C. Kim, S.-Y. Choi, and E.-Y. Park, “Anti-melanogenic effect of black, green, and white tea extracts in immortalized melanocytes,” J. Vet. Sci., 2015
[24]  Y. Kimura, M. Sumiyoshi, “French maritime pine bark (Pinus maritima Lam.) extract (Flavangenol) prevents chronic UVB radiation-induced skin damage and carcinogenesis in melanin-possessing hairless mice”, Photochem. Photobiol., 86, pp: 955–963, 2010
[25]  B. Ertam, I. Mutlu, I. Unal, S. Alper, B. Kivçak, and O. Ozer, “Efficiency of ellagic acid and arbutin in melasma: a randomized, prospective, open-label study,” J. Dermatol., 35, pp: 570–574, 2008
[26]  A. Dahl, M. Yatskayer, S. Raab, and C. Oresajo, “Tolerance and efficacy of a product containing ellagic and salicylic acids in reducing hyperpigmentation and dark spots in comparison with 4% hydroquinone,” J. Drugs Dermatol. JDD, 12, pp: 52–58, 2013
[27]   M.J. Stiller, J. Bartolone, R. Stern, “Topical 8% glycolic acid and 8% l-lactic acid creams for the treatment of photodamaged skin: A double-blind vehicle-controlled clinical trial”, Archives of Dermatology, 132, pp: 631-636,1996
[28]  C.M. Ditre, T.D. Griffin, G.F. Murphy, H. Sueki, B. Telegan, W.C. Johnson, “Effects of α-hydroxy acids on photoaged skin: Apilot clinical, histologic, and ultrastructural study”, Journal of the American Academy of Dermatology,34, pp:187-195, 1996
[29]  R. A. Newton, A. L. Cook, D. W. Roberts, J. H. Leonard, and R. A. Sturm, “Post-transcriptional regulation of melanin biosynthetic enzymes by cAMP and resveratrol in human melanocytes,” J. Invest. Dermatol, 127, pp: 2216–2227, 2007
[30]  T. H. Lee, J. O. Seo, S.-H. Baek, and S. Y. Kim, “Inhibitory Effects of Resveratrol on Melanin Synthesis in Ultraviolet B-Induced Pigmentation in Guinea Pig Skin,” Biomol. Ther, 22, pp: 35–40, 2014
[31]  J. H. Ryu, J. K. Seok, S. M. An, J. H. Baek, J. S. Koh, and Y. C. Boo, “A study of the human skin-whitening effects of resveratryl triacetate,” Arch. Dermatol. Res, 307, pp: 239–247, 2015
[32]  H. Jun, J. H. Lee, B.-R. Cho, W.-D. Seo, H.-W. Kang, D.-W. Kim, K.-J. Cho, and S.-J. Lee, “Dual inhibition of γ-oryzanol on cellular melanogenesis: inhibition of tyrosinase activity and reduction of melanogenic gene expression by a protein kinase A-dependent mechanism,” J. Nat. Prod., vol. 75, no. 10, pp. 1706–1711, Oct. 2012.
 
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Ascorbic Acid -L  (ultra fine powder)

L-ascorbic acid (vitamin C) is an essential nutrient which has many cosmetic benefits. It is a remarkable antioxidant and can scavenge reactive oxygen species and other free radicals, protecting the skin from oxidative stress. It can stimulate collagen synthesis by promoting cross-linking and stabilizing collagen molecules, upregulating collagen genes, increasing the transcription of the tissue inhibitor of matrix metalloproteinase 1, and inducing fibroblast proliferation. It reduces pigmentation by suppressing tyrosinase, which is important for melanin production. It is an anti-inflammatory agent and can be used to treat inflammatory skin disease such as erythema. Together, L-ascorbic acid provides powerful anti-aging properties and has been shown to reduce wrinkles, improve elasticity, and protect against sun damage. Stability and absorption of L-ascorbic acid is a concern. While the anhydrous L-ascorbic acid might be the most stable form, adding vitamin E not only helps stabilizing L-ascorbic acid, but the two have synergistic effects on anti-aging.  Used in: philosopy's turbo booster c powder and SkinCeuticals.

Key benefts of L-ascorbic acid in skin care:

  • Anti-inflammatory [31]
  • Antioxidant [4] [5] [6] [7] [8]
  • Increase skin elasticity [26]
  • Lightening and brightening [4] [22] [28] [29] [30]
  • Matrix metalloproteinases (MMP) inhibitors [19]
  • Moisturizing and hydration [21]
  • Reduce fine lines and wrinkles [7] [21] [22] [25] [26]
  • Ttimulate collagen production [5] [13] [14] [15] [16] [17] [18] [19] [20] [21] [22] [23] [24]
  • Sun damage protection [9] [11]
  • Sun damage repair [6] [22] [26]
  • Teat hyperpigmentation [4] [9] [22] [25] [28] [29] [30]
  • Wrinkle relaxers [22]
$7.10
Based on 4 reviews.
Ascorbyl Glucoside (Ascorbic Acid 2- Glucoside)
Ascorbyl glucoside (AA-2G) is a vitamin derivative, produced biologically by the reaction between glucose and vitamin C. This addition confers greater stability, compared to relatively unstable pure ascorbic acid, thus allowing for wide usage in pharmacy and cosmetics. AA-2G retains the antioxidant properties of the unmodified vitamin, therefore it is used to prevent radiation damage, cell senescence and skin darkening. It also promotes collagen synthesis, as well as cell proliferation – these mechanisms help improve the appearance of the skin and reduce wrinkles. Furthermore, since AA-2G does not release ascorbic acid instantly, all the listed positive effects are sustained longer and the possibility of adverse effects is reduced, compared to using pure ascorbic acid. All these qualities make AA-2G the most attractive vitamin C derivative for cosmetic use.

Key benefits of Ascorbyl glucoside (AA-2G)  in skin care:

  • Antioxidant [10] [16]
  • Lightening and brightening [14]
  • Treat hyperpigmentation [14]
  • Sun damage repair [10] [16]
  • Sun dammage protection [7] [9]
  • Stimulate collagen production [3] [13]
  • Reduce fine lines and wrinkles [12]
$21.30
Ascorbyl Tetraisopalmitate

Ascorbyl tetraisopalmitate (Tetrahexyldecyl Ascorbate) is a molecule derived from vitamin C and isopalmitic acid. Pure vitamin C has several drawbacks for cosmeceutical use, most important of which is the low stability. Chemically modified vitamin molecules are more stable, and pure vitamin is released from the derivatives inside the body. Therefore, the effects of Ascorbyl Tetraisopalmitate are similar to those of vitamin C, most importantly it is able to act as an antioxidant. Ascorbyl tetraisopalmitate reduces the production of oxidizing agents, which contribute to cell damage after exposure to UV or chemical hazards. This effect is even stronger in the modified molecule than in pure vitamin C. Additionally, Ascorbyl Tetraisopalmitate protects against DNA damage and skin darkening caused by UV exposure. Finally, skin visual appearance is also improved by Ascorbyl tetraisopalmitate, as it promotes collagen synthesis and acts as a hydrating agent in reducing skin roughness.

Key benefits of Ascorbyl tetraisopalmitate in skin care:

  • Sun damage protection [1] [2] [7]
  • Sun damage repair [2]
  • Antioxidant [1] [6]
  • Moisturizing and hydration [5]
  • Stimulate collagen production [2]
  • Lightening & brightening [1]
  • treat hyperpigmentation [1]
$86.90
Based on 3 reviews.
CoQ10 (CoEnzyme Q10)

Coenzyme Q10 is a molecule naturally involved in energy metabolism in all human cells. Among its many benefits, the antioxidant properties are the most researched. This molecule can prevent oxidation damage to water-insoluble molecules, DNA mutations, collagen synthesis decrease, pigmentation, inflammation and other adverse effects associated with UV exposure and ageing. In combination with vitamin E or other antioxidants, an exceedingly strong antioxidative effect can be achieved. Furthermore, coenzyme Q10 has a unique capability to protect against infrared A radiation, which is also found in sunlight. The promotion of collagen synthesis makes this coenzyme useful in treating ageing-associated skin changes, such as wrinkle appearance. Finally, its anti-inflammatory effect is beneficial not only for UV-damaged skin, but also for wound healing support.

NOTE: To assist you with solubility issues, we now also sell CoQ10 (Coenzyme Q10) as a liquid standardized pre-dissolved solution. Just add the liquid to your cream and mix well.

Key benefits of Coenzyme Q10 in skin care:

  • Sun damage protection [5] [7] [9]
  • Antioxidant [1] [3] [4] [5] [6] [7] [8]
  • Increase cellular energy production [15]
  • Stimulate collagen production [5] [8] [10] [13]
  • Lightening & brightening [10]
  • Sun damage repair [5] [7] [8]
  • Reduce fine lines & wrinkles [5] [11]
  • Wound healing support [13]
  • Anti-inflammatory [6] [10] [12] [13]
$17.20
Ethyl Ascorbic Acid

Ethyl ascorbic acid is a molecule produced by modifying ascorbic acid, commonly known as vitamin C. This modification is done to increase the molecule’s stability and enhance its transport through skin, as pure vitamin C is easily degraded. In the body, the modifying group is removed and vitamin C is restored in its natural form. Thus, ethylascorbic acid retains the benefits of vitamin C, such as antioxidant activity. Furthermore, it is even more potent in reducing skin darkening after UV exposure. It even has some additional effects, not observed in pure ascorbic acid, such as promoting nerve cell growth or reducing chemotherapy damage. Finally, the slower release also ensures that no toxic effects are observed when using this vitamin C derivative.

Key benefits of Ethyl ascorbic acid in skin care:

  • Stimulate collagen production [5] [6]
  • Lightening & brightening [5] [7] [9] [9]
  • Treat hyperpigmentation [5] [7] [8] [9]
  • Sun damage protection [8] [9]
$17.50
Based on 1 reviews.
Ferulic acid (Natural)
Ferulic acid is a plant compound with numerous known health benefits. It is absorbed efficiently through skin, where it is effective as a strong antioxidant. Most often it is used in combination with vitamins C and E – this way, the individual benefits of each ingredient are strengthened, resulting in very effective UV protection. This combination even prevents DNA damage and cancer formation. The antioxidant protection is stable, remains safe from rubbing and sweating, and even resistant to natural chemical degradation, giving the product a long shelf-life. Ferulic acid alone is also beneficial, as it can restore collagen synthesis after UV exposure and thus reduce the symptoms of skin ageing. These properties make it a desirable component in sunscreens and antioxidant formulations.

NOTE: To assist you with solubility issues, we now sell Ferulic acid in three liquids: pre-dissolved solution, lipsome microemulsion, and ethosome microemulsion. Just add the liquid to your cream and mix well.
  • 6% pre-dissolved solution gives 0.5% Ferulic Acid content in final product.
  • 31% pre-dissolved solution gives 3% Ferulic Acid content in final product.
  • 51% pre-dissolved solution gives 5% Ferulic Acid content in final product.
Ferulic acid is commonly used in the Skinceuticals C+E Ferulic serum.  C E Ferulic is a revolutionary antioxidant combination that delivers advanced protection against photoaging by neutralizing free radicals, boosting collagen synthesis, and providing unmatched antioxidant protection. More protection means more youthful looking skin and better defense against environmental aging.

Key benefits of Ferulic acid in skin care:

  • Sun damage protection [4] [5]] [6] [7] [8] [9] [10]
  • Sun damage repair [9] [10] [13] [14]
  • Antioxidant [1] [3] [7] [8] [9]
  • Stimulate collagen production [13] [14]
  • Lightening & brightening [15]
  • Anti-androgenetic alopecia [3]
  • Stabilizes l ascorbic acid [5]
$8.35
Based on 2 reviews.
Glucosamine (N-Acetyl Glucosamine)

N-acetyl glucosamine is a compound with a wealth of uses for improving skin condition. It is a known precursor to hyaluronic acid, a major component of skin structure. Hyaluronic acid is essential for hydration and n-acetyl glucosamine has been shown to increase moisture. N-acetyl glucosamine helps heal wounds, increase collagen, and reduce acne. It reduces hyperpigmentation, especially when combined with niacinamide, a member of the vitamin B3 family. It has anti-oxidant and anti-inflammatory properties which allow it to help heal and prevent sun damage. Overall, this compound can help prevent premature aging and reduce signs of aging, such as wrinkles, especially when combined with niacinamide.

Key benefits of Glucosamine in skin care:

  • Stimulate HA production [2] [3] [4] [5] [6] [7] [8] [9] 10]
  • Moisturizing and hydration [2] [5] [9] [11]
  • Treat hyperpigmentation [2] [4] [9]
  • Wound healing support [2] [11]
  • Stimulate collagen production [11]
  • Scar care [2]
  • Anti-acne [2] [6]
  • Anti-inflammatory [2] [3]
  • Anti-oxidant [2] [7]
  • Sun damage repair [1] [7]
  • Sun damage protection [7]
  • Increase skin elasticity [5] [11]
  • Reduce fine lines and wrinkles [2] [10]
  • Matrix metalloproteinases [MMP] inhibitors [7]
$8.20
Based on 1 reviews.
Green Tea (90% EGCG)
Green tea has numerous benefits in almost all aspects of skin care. The main active ingredient, EGCG, is a potent antioxidant, and protects skin from UV damage. This results in reduced wrinkling, increased collagen content, smoother skin, thicker and more elastic epidermis and other visual benefits. Green tea also helps to moisturize the skin and improves the long-term barrier capabilities. Among the numerous clinical benefits are antibacterial and antifungal effects, which make green tea useful in wound care. Most important health effect is the prevention of melanoma and other types of skin cancer, resulting partly from the EGCG capability to neutralize free radicals and activate DNA repair. Since the extract also reduces inflammation and sebum secretion, it is an effective treatment against acne. Finally, green tea has also been proven to reduce hair loss and follicle death. Active ingredient in Teamine™ and ReVive™ lines.

NOTE: To assist you with solubility issues, we now also sell Green Tea EGCG in a standardized, pre-dissolved solution. Just add the liquid to your cream and mix well.
  • 11% solution gives 1% EGCG content in final product.
  • 33% solution gives 3% EGCG content in final product.
  • 54% solution gives 5% EGCG content in final product.

Key benefits of Green Tea EGCG in skin care:

  • Sun damage protection [1] [2] [3] [4] [5]
  • Sun damage repair [1] [2] [3]
  • Antioxidant [1] [2] [3] [7]
  • Capillary health [19]
  • Moisturizing & hydration [8] [9] [11]
  • Reduce fine lines and wrinkles [10] [11]
  • Wound healing support [17] [18]
  • Oil/sebum control [12]
  • Lightening & brightening [6]
  • Restore barrier function [8] [9]
  • Anti-inflammatory [1]
  • Anti-acne [12] [13]
  • Anti-bacterial [13] [14] [16]
$17.05
Based on 5 reviews.
Hesperidin methyl chalcone
Hesperidin is a a plant flavonoid, found naturally in citrus fruits. It has numerous biological benefits, but it is poorly absorbed and transported in the body, hence a modified version, hesperidin methyl chalcone (HMC), is used in cosmetics. The best known effect of HMC is reduction of capillary permeability. This can be used to reduce dark circles and bags under the eyes or even treat varicose veins. It is also known to reduce melanin synthesis, thus lightening the skin, and it also protects skin from UV-caused damage and cell ageing. Furthermore, HMC restores the barrier function of the skin, improving hydration, regulating pH and promoting skin cell proliferation. Finally, it has an anti-inflammatory effect, and can even be used to reduce various types of pain caused by inflammation.

NOTE: To assist you with solubility issues, we now also sell Hesperidin methyl chalcone as a liquid standardized pre-dissolved solution. Just add the liquid to your cream and mix well.
  • 11% solution gives 1% Hesperidin content in final product.
  • 31% solution gives 3% Hesperidin content in final product.
  • 51% solution gives 5% Hesperidin content in final product.

Key benefits of Hesperidin methyl chalcone in skin care:

  • Sun damage protection [8] [11]
  • Capillary health [4] [5] [12]
  • Lightening & brightening [7] [8]
  • Reduce dark circles under the eyes [6]
  • Restore barrier function [1] [9] [10]
  • Anti-inflammatory [2] [5]
$12.60
Lemon Peel Bioferment
Our lemon peel bioferment uses fermentation as a method to extract valuable chemicals from the peel, releasing them to be used by our skin.  Lemon peel bioferment  is an antioxidant, inhibitor of melanin synthesis, and bactericide. Tyrosinase inhibition is similar to that obtained with hydroquinone. Lemon peel extract has anti-tyrosinase activity as high as hydroquinone.

Key benefits of Lemon Bioferment in skin care: 

  • antioxidant
  • skin lightening and brightening
  • inhibitor of melanin synthesis
  • inhibits tyrosinase
  • increased luminosity
  • bactericide
  • non sensitizing
  • not cytotoxic
$23.89
Niacinamide (Vitamin B3)
Niacinamide, also known as nicotinamide, is a water soluble form of vitamin B3. Vitamin B3 is essential for maintaining skin health. Niacinamide increases production of important skin structural components such as collagen, ceramide, and keratin. This helps increase moisture and strengthen skin. Niacinamide is known to decrease hyperpigmentation, effectively lightening and brightening skin, especially when used together with n-acetyl glucosamine, a hyaluronic acid precursor. It reduces wrinkles and again, this effect is better with n-acetyl glucosamine. Niacinamide also effectively helps reduce acne and heal wounds. It has anti-oxidant and anti-inflammatory properties. Overall, niacinamide is a compound with many different uses that can increase overall skin health.

Key benefits of Niacinamide in skin care:

  • Treat hyperpigmentation [3] [7] [8]
  • Lightening and brightening [3] [7] [8]
  • Reduce fine lines and wrinkles [9]
  • Anti-inflammatory [5] [6] [8]
  • Anti-oxidant [10] [13]
  • Anti-acne [1] [5] [11]
  • Moisturizing and hydration [2] [5] [12]
  • Restore barrier function [2] [5] [12]
  • Wound healing support [5] [6]
  • Increase skin elasticity [5] [9]
  • Oil/sebum control [2]
  • Pore refinement [2]
  • Sun damage repair [13]
  • Sun damage protection [10]
  • Stimulate collagen production [5]
  • Stimulate HA production [9]
$6.60
Pumpkin Enzyme Peel (Pumpkin Bioferment)
Our Pumpkin Bioferment  is a natural, gentle enzyme "peel" that you can use straight from the bottle or add to any lotion or cream. Pumpkin (Cucurbita pepo) proteases hydrolyze the proteins, exfoliating dead skin cells and impurities while delivering vitamins and nutrients to the skin. The Pumpkin Enzyme Peel leaves the skin cleansed and silky smooth. Pumpkin proteases and nutrients are released from fresh pumpkin cells by the action of the same organism that transforms milk into yoghurt.

Key benefits of Pumpkin Enzyme Peel (Pumkin Bioferment) in skin care: 

  • natural gentle and safe enzyme peel
  • enzymatically excite cell turnover
  • unblock pores and dissolve oils
  • remove blackheads
  • improve skin texture and tone due to exfoliation properties
  • treat hyperpigmentation.
$23.30
Based on 1 reviews.
Resveratrol (Trans-resveratrol 98%)
Resveratrol is a compound found in grapes and many other plants. It is currently investigated in many skincare applications. Resveratrol protects cells from oxidative stress – it is an antioxidant itself, and activates the synthesis of other such compounds. It also regulates inflammatory responses and even aids the distribution of cosmetical sunscreens, thus helping to prevent UV damage to the skin. Similarities in structure allow resveratrol to replace estrogen in post-menopausal women, helping to reduce collagen loss and reduce skin ageing symptoms. Additionally, it counters photoageing by inhibiting melanin synthesis, resulting in lighter skin and less pigmented spots. Even acne can be alleviated by applying resveratrol, as it has antibacterial properties and controls sebaceous cell growth. Finally, it is a promising agent in melanoma prevention, able to delay the emergence and reduce the size of skin tumors.

NOTE: To assist you with solubility issues, we now also sell Resveratrol in a standardized  pre-dissolved solution. Just add the liquid to your cream and mix well.

Key benefits of Resveratrol in skin care:

  • Anti-acne [15]–[17]
  • Anti-bacterial [16]
  • Antioxidant [1]–[4]
  • Anti-inflammatory [1], [4], [8], [9]
  • Sun damage protection [1], [6]–[8], [11]
  • Increase skin elasticity [14]
  • Lightening & brightening [10]–[13]
  • Natural phytoestrogens [1], [8], [9]
$7.10
Sodium Ascorbyl Phosphate (SAP)
Vitamin C, or ascorbic acid, is one of nature’s most powerful antioxidants.As the natural aging process and environmental hazards increase the amount of free radicals in the skin, ascorbic acid and its derivatives can effectively neutralize these damaging agents and prevent further damage.Ascorbic acid has been shown to increase the synthesis of collagen in the skin to reduce the appearance of wrinkles and to block the melanin synthesis pathway, reducing age spots and lightening skin.Unfortunately, ascorbic acid is not stable in aqueous solutions and is quickly degraded.The hydrophilic ascorbic acid derivative sodium ascorbyl phosphate is significantly more shelf-stable in solutions and, as it is converted to ascorbic acid in skin, retains all of the skin-benefitting aspects of vitamin C.Therefore sodium ascorbyl phosphate is the ideal choice for anti-aging emulsion creams.

Key benefits of Sodium Ascorbyl Phosphate in skin care:

  • Anti-acne [7]  [8]
  • Antioxidant [3] [4] [6] [9] [10]
  • Increase skin elasticity [1] [4]
  • Reduce fine lines and wrinkles [1] [4]
  • Stimulate collagen production [1] [4]
  • Sun damage protection [9] [10]
  • Sun damage repair [9] [10]
  • Lightening and brightening [12]
  • Treat hyperpigmentation [12]
$13.30
Yeast Beta Glucan

Glucan is a polymer, produced from glucose molecules in fungi, seaweed and other organisms. Many types of this polymer exist, but yeast beta-glucan has the optimal structure and size for biological activity. It has significant effects in wound healing – glucan is already used to treat burn patients, as it promotes regeneration of the skin, reduces pain and improves scar appearance. Furthermore, it is able to activate the immune system to fight against infections, making it additionally useful in open wound care. Additionally, it helps the skin to maintain its barrier function after damage by chemicals, such as detergents. The antioxidant properties of this polymer help protect the skin cells against UV or other sources of oxidative damage. Skin ageing symptoms, such as darkening, sunburn and collagen degradation, can also be reduced by applying this compound.


Key benefits of Yeast Beta Glucan in skin care:

  • Sun damage protection [1], [5], [11]
  • Sun damage repair [1], [5], [11]
  • Wound healing support [1], [4]–[8]
  • Anti-bacterial [9], [10]
  • Scar care [8]
  • Lightening & brightening [1]
  • Antioxidant [1], [5], [11]
  • Restore barrier function [5]
$13.70
Magnesium Ascorbyl Phosphate (MAP)
Magnesium Ascorbyl  Phosphate (MAP) is a water soluble magnesium salt of  ascorbic acid. It is very stable, has great bioavailability and a neutral PH. On the skin, MAP has beneficial effects – similar to vitamin C: antioxidant, anti-inflammatory, boosts skin elasticity, lightening, hydrating, and wound healing, photo-protective. MAP is also easy to use and incorporate in DIY formulation both in aqueous and oil in water emulsions.


Key benefits of Magnesium Ascorbyl Phosphate (MAP) in skin care:

  • Antioxidant [3-15]
  • Increase skin elasticity [5] [11]
  • Stimulate collagen production [5] [11]
  • Sun damage protection [9] [10] [11]
  • Sun damage repair [9] [10] [11]
  • Lightening and brightening [12] [13] [14][15]
  • Treat hyperpigmentation [12] [13] [14][15]
$10.60
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