Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
Reviews
I wished i could order this in a smaller amount of 50 gr. Can i get informed when it is available ? -------------------- A. It will not be sold in smaller amounts. The review rating is meant to be for the product, not the size in which it is sold :-(.. ...»
Diana
Excellent quality, very fine texture and disperses easily when used correctly. Arrived in just seven days to London, England and with a reasonable postage fee. Very pleased... ...»
D N Bay
I bought this product before and I am here to buy it again! A high quality product for really good price... .. Thanks!.. ...»
Raisa
As all products from bulkactives, this is a really great and high-quality DYI ingredient. Along with John's friendly, reliable and very efficient service, it makes a purchase from bulkactives a very pleasant experience... ...»
Sandra
I mixed it with some other water actives like Glucosamine, Niacinamide, Glutathione etc into the Pre Liposome Microemulsion and the serum was very smooth and moisturizing. As it claims, it penetrates into the skin very well. I will mix it with oil soluble actives in my next batch. .. ...»
RRR
Awesome Product and thanks for such a nice Product description .. ...»
Stephen
Excellent product! Easy to use. Add to your cream or oil, mix, and that's it! After applying cream with peptides, my skin was really smooth and nourishing. Very happy that BulkActives offers such high quality product for really good price... ...»
Nativa
Great product! I've added this emulsion to different DYI combinations to include serums and creams with wonderful results. It's a light, smooth product that mixes easily into my formulations. As earlier reviewer mentioned, I especially like the emulsion when mixed with the incredible multi-lamellar IV cream. Also, can't beat the price for such a quality product... ...»
Annabelle
Hi, Ordered this about 5 weeks ago, so I been waiting to DIY and try the product before I left a review. I mixed Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 Liposome Emulsion, 3/4 tsp, with 3tsps distilled water and 3/4 tsp of rose hip oil. It makes a beautiful light weight serum that I apply at night. You can feel tightening within a few minutes. The tightening subsides in half hour or so and then I apply a moisturiser. Another excellent buy from Bulk Actives. .. ...»
Jan Greenwood
I've been using glucosamine in combination with niacinamide as an addition to my moisturizer to combat dark spots on face and hands. Used twice daily, it does seem to keep them from darkening. Of course, you still need to be religious about using a sunscreen every time you are in the sun. .. ...»
Lorraine
Secure Payments
Orders Securely Processed Through PayPal
PayPal
 Visa  Mastercard  Discover  American Express
 

SSL Certificate

As Featured On EzineArticles

Google+

 

 

 

Important Stuff

 All customers PLEASE read:

 the FAQ and Delivery Info pages!

Canadian Customers:

Any long delivery delays are caused by The Canada Border Services Agency.
I now ONLY offer EMS as a shipping option to Canada. 
This appears to have resolved most of the delays caused by The Canada Border Services Agency.

Please write your correct address:

We take NO responsibility for delivery issues caused by customers entering the wrong address in the checkout page

Delivery

BulkActives is a part-time business. Orders are processed and mailed on Saturdays. (TimeZone Order Deadline Chart)

What we sell

We sell  COSMETIC RAW MATERIALS, which are meant to be used at an appropriate percentage in a cosmetic formulation of your devising. Please do not order our products unless you know how to formulate creams and lotions with it!  

Forgotten your password? Not receiving lost password emails? Can't create an account?

NO PROBLEM!  Just email me, and I will sort it all out.

Not receiving order status email updates?

Please check your JUNK mail folder for our emails, and mark them as NOT SPAM.

Failing to do so will result in NOT receiving ANY transaction / order status email updates.

Recipe % calculator

Download our SIMPLE RECIPE CALCULATOR (MS Excel)

Sample Recipes

Download sample recipes RAR file

Newsletter
* E-mail Address:
* Name:
Recent Articles

Antioxidants for sun damage protection (photoprotection)

How the skin naturally protects itself and the advantages of topical antioxidants for photoprotection The...

Read article


Ascorbyl Glucoside in Skin Care (AA2G, stable Vitamin C)

Ascorbyl Glucoside or AA2G is a derivative of vitamin C that has been biochemically modified to make...

Read article


Anhydrous C for skin care: L-ascorbic in silicone

Anhydrous C for skin care: absorption of L-ascorbic in a silicone base Anhydrous C is a skin care product...

Read article


Enhancing skin tone and reversing the effects of ageing

Enhancing skin tone and reversing the effects of ageing It is only in recent times that researchers...

Read article


How to boost collagen production in skin

What is Collagen? Collagen is a major structural protein in the skin. It plays a key role in providing...

Read article


Alcohol as Solvent in DIY Skin Care Products

Alcohol is a generic name for organic chemical compounds usually obtained through fermentation. Despite...

Read article


Hyperpigmentation,Melasma, and Skin Color Explained

The enzyme tyrosinase converts the amino acid tyrosine into melanin in the skin. Hyperpigmentation can...

Read article


Improve skin tone and reverse the effects of aging

Latest developments in agents that improve skin tone and reverse the effects of aging Beauty, they say,...

Read article


Made in China - Getting to the Heart of the Matter

After getting a couple of emails about products manufactured in China, I wanted to take the time to write...

Read article


Exfoliating: Mild Chemical Exfoliating in Skin Care

Exfoliating is a cosmetic procedure that involves the removal of dead skin cells that accumulate in the...

Read article


Multi Lamellar Creams and Emulsions

Multi Lamellar Emulsions (MLE) The protective properties of our skin are determined by its complex biological...

Read article


Oat Beta Glucan Skin Care

Oat Beta Glucan Skin Care - Anti Wrinkle Skin Care and Skin Texture Improvements Oat beta glucan has...

Read article


UV Skin Damage - Photodamage and Photoaging

UV skin damage: Photodamage, photoaging and other ways in which the skin changes due to exposure to UV...

Read article


Skin Lightening Process and Pigmentation Formation

Pigmentation formation and skin lightening process Melanin is mainly responsible for skin pigmentation,...

Read article


Resveratrol – nature’s most powerful and potent anti-aging agent yet

The process of aging is one that man has battled with for a long time. A lot of research has been done...

Read article


Rosehip Oil and Vitamin A in Skin Care

Rosehip oil is widely recognized for the effects of the natural topical trans-retinoic acid (vitamin...

Read article


Silymarin Skin Health – Antioxidant & Anti-inflammatory

Silymarin Skin Health – Antioxidant, Anti-inflammatory, Skin Cancer Preventative In the world of skin...

Read article


Exfoliating Skin with Salicylic Acid

Salicylic acid - a beta hydroxy acid as anti-inflammatory, exfoliating, and anti acne active What is...

Read article


soy isoflavones skin benefits

Soy isoflavones skin benefits in anti aging skin care Research suggests that estrogen deficiencies...

Read article


Sunscreens With Vitamin A are Potentially Harmful for Skin

Sunscreens With Vitamin A are Potentially Harmful for Skin The impact of vitamin A on skin health has...

Read article


Antioxidants for sun damage protection (photoprotection)

How the skin naturally protects itself and the advantages of topical antioxidants for photoprotection The...

Read article

Ascorbyl Glucoside in Skin Care (AA2G, stable Vitamin C)

Ascorbyl Glucoside or AA2G is a derivative of vitamin C that has been biochemically modified to make...

Read article

Anhydrous C for skin care: L-ascorbic in silicone

Anhydrous C for skin care: absorption of L-ascorbic in a silicone base Anhydrous C is a skin care product...

Read article

Enhancing skin tone and reversing the effects of ageing

Enhancing skin tone and reversing the effects of ageing It is only in recent times that researchers...

Read article

How to boost collagen production in skin

What is Collagen? Collagen is a major structural protein in the skin. It plays a key role in providing...

Read article

Alcohol as Solvent in DIY Skin Care Products

Alcohol is a generic name for organic chemical compounds usually obtained through fermentation. Despite...

Read article

Hyperpigmentation,Melasma, and Skin Color Explained

The enzyme tyrosinase converts the amino acid tyrosine into melanin in the skin. Hyperpigmentation can...

Read article

Improve skin tone and reverse the effects of aging

Latest developments in agents that improve skin tone and reverse the effects of aging Beauty, they say,...

Read article

Made in China - Getting to the Heart of the Matter

After getting a couple of emails about products manufactured in China, I wanted to take the time to write...

Read article

Exfoliating: Mild Chemical Exfoliating in Skin Care

Exfoliating is a cosmetic procedure that involves the removal of dead skin cells that accumulate in the...

Read article

Multi Lamellar Creams and Emulsions

Multi Lamellar Emulsions (MLE) The protective properties of our skin are determined by its complex biological...

Read article

Oat Beta Glucan Skin Care

Oat Beta Glucan Skin Care - Anti Wrinkle Skin Care and Skin Texture Improvements Oat beta glucan has...

Read article

UV Skin Damage - Photodamage and Photoaging

UV skin damage: Photodamage, photoaging and other ways in which the skin changes due to exposure to UV...

Read article

Skin Lightening Process and Pigmentation Formation

Pigmentation formation and skin lightening process Melanin is mainly responsible for skin pigmentation,...

Read article

Resveratrol – nature’s most powerful and potent anti-aging agent yet

The process of aging is one that man has battled with for a long time. A lot of research has been done...

Read article

Rosehip Oil and Vitamin A in Skin Care

Rosehip oil is widely recognized for the effects of the natural topical trans-retinoic acid (vitamin...

Read article

Silymarin Skin Health – Antioxidant & Anti-inflammatory

Silymarin Skin Health – Antioxidant, Anti-inflammatory, Skin Cancer Preventative In the world of skin...

Read article

Exfoliating Skin with Salicylic Acid

Salicylic acid - a beta hydroxy acid as anti-inflammatory, exfoliating, and anti acne active What is...

Read article

soy isoflavones skin benefits

Soy isoflavones skin benefits in anti aging skin care Research suggests that estrogen deficiencies...

Read article

Sunscreens With Vitamin A are Potentially Harmful for Skin

Sunscreens With Vitamin A are Potentially Harmful for Skin The impact of vitamin A on skin health has...

Read article

Glucosamine (N-Acetyl Glucosamine)

N-acetyl glucosamine is a compound with a wealth of uses for improving skin condition. It is a known precursor to hyaluronic acid, a major component of skin structure. Hyaluronic acid is essential for hydration and n-acetyl glucosamine has been shown to increase moisture. N-acetyl glucosamine helps heal wounds, increase collagen, and reduce acne. It reduces hyperpigmentation, especially when combined with niacinamide, a member of the vitamin B3 family. It has anti-oxidant and anti-inflammatory properties which allow it to help heal and prevent sun damage. Overall, this compound can help prevent premature aging and reduce signs of aging, such as wrinkles, especially when combined with niacinamide.

Key benefits of Glucosamine in skin care:

  • Stimulate HA production [2] [3] [4] [5] [6] [7] [8] [9] 10]
  • Moisturizing and hydration [2] [5] [9] [11]
  • Treat hyperpigmentation [2] [4] [9]
  • Wound healing support [2] [11]
  • Stimulate collagen production [11]
  • Scar care [2]
  • Anti-acne [2] [6]
  • Anti-inflammatory [2] [3]
  • Anti-oxidant [2] [7]
  • Sun damage repair [1] [7]
  • Sun damage protection [7]
  • Increase skin elasticity [5] [11]
  • Reduce fine lines and wrinkles [2] [10]
  • Matrix metalloproteinases [MMP] inhibitors [7]
Product Code: BulkActives
Reward Points: 3
Assay: 99.5%
CAS#: 10036-64-3
Net weight: 30g /1.06oz
Availability: In Stock
Price: $6.70
Reward Points: 335


    - OR -   Add to Wish List
Add to Compare
Did you find this somewhere else for less? Let us know and we'll match it! (conditions apply)
×
* Name:
* Email:
Telephone:
* Competitor link
* Competitor price
Message

About N-acetyl Glucosamine in DIY Skin Care

N-acetyl glucosamine is an amino sugar present in all human tissues [7]. It is a stable form of glucosamine that penetrates skin easily [4]. It is a good cosmetic, as high concentrations of n-acetyl glucosamine do not cause irritation [9]. N-acetyl glucosamine is a precursor to hyaluronic acid, also known as hyaluronan [2]. Hyaluronic acid is a large component of connective tissue and has roles in both skin structure and hydration. The molecule is known to hold water in the skin, increasing moisture [11]. Hyaluronic acid is present in the epidermis and stratum corneum, two different layers of the skin [9]. Cosmetic formulations including n-acetyl glucosamine have many advantages.
 
Topical n-acetyl glucosamine decreases flakiness, increases skin hydration, and has exfoliating properties [9]. It has been studied as an alternative to alpha hydroxy acids, compounds commonly found in commercial anti-aging treatments that can irritate skin and increase UV damage. An increase in skin elasticity, thickness, and plumping was seen after 8% n-acetyl glucosamine application [5].
 
One of n-acetyl glucosamine’s most studied topical uses is for reducing hyperpigmentation [4]. In a clinical study 2% NAG applied topically significantly reduced hyperpigmentation. This is because n-acetyl glucosamine inhibits tyrosinase activation. Tyrosinase is an enzyme involved in melanin synthesis [4]. Hyperpigmentated age spots are localized accumulations of melanin. Thus, by keeping tyrosinase from becoming activated, the amount of melanin produced is less, which decreases the appearance of age spots. When combined with 4% niacinamide, a member of the vitamin B3 family, the pigmentation reducing effect was greater [4, 9]. This shows n-acetyl glucosamine and niacinamide should ideally be used together to produce better results.
 
An in vitro [outside the body] study shows there is an age-related decrease in glucosamine incorporation into hyaluronic acid. This contributes to wrinkle formation [2]. Studies show that applying n-acetyl glucosamine topically increases hyaluronic acid amounts in the skin [2]. This effect is greater when combined with niacinamide, which is a cofactor in hyaluronic acid synthesis [10]. A clinical study using topical 2% n-acetyl glucosamine showed a reduced appearance of wrinkles [2]. Women using a 2% n-acetyl glucosamine and 4% niacinamide cream showed a larger improvement in fine lines and wrinkles, especially under the eyes [10]. Glucosamine compounds are also known to have anti-inflammatory characteristics [3]. Inflammation can accelerate skin aging, so anti-inflammatory products are useful for preventing this change.
 
Topical n-acetyl glucosamine also reduces acne [2, 6]. In a clinical study, 8% n-acetyl glucosamine was less drying and irritating than benzoyl peroxide, commonly applied to treat acne [6]. It also helped eliminate acne and was able to reduce acne faster than benzoyl peroxide [6].
 
N-acetyl glucosamine increases activity of antioxidant enzymes, thus reducing the amount of harmful free radicals produced after UV exposure. Hyaluronic acid is also known to scavenge free radicals [2]. N-acetyl glucosamine also inhibits matrix metalloproteinases [MMP] that degrade collagen after UV damage [7]. It increases the viability of skin cells exposed to UV radiation. It has also shown to be useful for the prevention of photoaging [premature skin aging due to excessive sun exposure]. Also, hyaluronic acid levels decrease after UV radiation exposure and in sunburned skin [1]. Thus, replenishing hyaluronic acid through application of n-acetyl glucosamine may help heal sun damage.
 
N-acetyl glucosamine also increases collagen production by fibroblasts [collagen producing cells] [11]. Collagen is important for the structural support of skin. It aids in wound healing and improving elasticity. This study shows the fibroblasts were able to regenerate faster after injury in the presence of n-acetyl glucosamine [11]. Additionally, maintaining an abundance of hyaluronic acid in wounds during the healing process produces better results with less scar formation [2].

WARNING

Seafood allergy?

ALL commercially produced Glucosamine, including ours, is manufactured from the shells of crabs and shrimps.

Assay: 99.5%
CAS#: 10036-64-3
Chemical Name: N-acetyl-.alpha.-D-glucosamine
INCI: acetyl glucosamine
Source: ALL commercially produced Glucosamine, including ours, is manufactured from the shells of crabs and shrimps.
Appearance: white powder
Solubility: water
Suggested percentage: 4% Glucosamine with 2% Niacinamide.    No other data available - up to customer's discretion. (One DIYer is succesfully using 10% NAG in water with Propylene Glycol.)

Storage: Store in cool and dry place. Keep away from direct strong light and heat.
Country of origin: China

[1]   M. Averbeck, C.A. Gebhardt, S. Voigt, S. Beilharz, U. Anderegg, C.C. Termeer, J.P. Sleeman, and J.C. Simon, “Differential Regulation of Hyaluronan Metabolism in the Epidermal and Dermal Compartments of Human Skin by UVB Irradiation,” Journal of Investigative Dermatology, vol. 127, pp. 687–697, 2007.
[2]  D.L. Bissett, “Glucosamine: an ingredient with skin and other benefits,” Journal of Cosmetic Dermatology, vol. 5, pp. 309–315, 2006.
[3]  D.L. Bissett, T. Farmer, S. McPhail, T. Reichling, J.P. Tiesman, K.D. Juhlin, G.J. Hurley, and M.K. Robinson, “Genomic expression changes induced by topical N-acetyl glucosamine in skin equivalent cultures in vitro,”
[4]  D.L. Bissett, L.R. Robinson, P.S. Raleigh, K. Miyamoto, T. Hakozaki, J. Li, and G.R. Kelm, “Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine,” Journal of Cosmetic Dermatology, vol. 6, pp. 20–26, 2007.
[5]  B.A. Green, B.L. Edison, R.H. Wildnauer, and R.H. Hwu, “Derivatives of Sugar Compounds Provide Anti-Aging Effects,” Amer Acad of Dermatol Poster Exhibit: Washington, DC, February 2004.
[6]  B.A. Green, R.H. Wildnauer, and B.L. Edison, “Topical N-Acetyl Glucosamine Provides Fast Acne-Reducing Benefits and Mildness Demonstrating Its Potential Utility in Enhancing Conventional Rx or OTC Acne Treatments,” Amer Acad of Dermatol Poster Exhibit, Washington, DC: February 2007.
[7]  Y.P. Hwang, H.G. Kim, E.H. Han, J.H. Choi, B.H. Park, K.H. Jung, Y.C. Shin, and H.G. Jeong, “N- Acetylglucosamine suppress collagenases activation in ultraviolet B-irradiated human dermal  fibroblasts: Involvement of calcium ions and mitogen-activated protein kinases,” Journal of Dermatological Science, vol. 63, pp. 93–103, 2011.
[8]  A.B. Kimball, J.R. Kaczvinsky, J. Li, L.R. Robinson, P.J. Matts, C.A. Berge, K. Miyamoto, and D.L. Bissett, “Reduction in the appearance of facial hyperpigmentation after use of moisturizers  with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial,” British Journal of Dermatology, vol. 162, pp 435–441, 2010.
[9]  T. Mammone, D. Gan, C. Fthenakis, and K. Marenus, “The effect of N-acetyl-glucosamine on stratum corneum desquamation and water content in human skin,” J. Cosmet. Sci., vol. 60, pp. 423–428, July 2009.
[10]   R. Osborne, L. A. Mullins, and L. R. Robinson, “Topical N-Acetyl Glucosamine and Niacinamide Increase Hyaluronan,” The Procter & Gamble Company, Cincinnati, Ohio USA.
[11]  A. Połubinska, J. Cwalinski, E. Baum, and A. Brezborowicz, “N-Acetylglucosamine modulates function of the skin fibroblasts,” International Journal of Cosmetic Science, vol. 35, pp. 472– 476, 2013.
 

Write a review

Your Name:


Your Review: Note: HTML is not translated!

Rating: Bad           Good

Enter the code in the box below:



(c) BulkActives 2005-2017