Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
Tried this on my week-old rash from flea bites. Got an almost instant relief and rash healed in 2 days. Tried it on my daughter who has eczema for a very long time. The rashes calmed down after a few days and her skin is now healing well. Really great product. Just put in order for another jar.... ...»
Wonderful base cream! Only multi-lamellar structured cream I've found on the market. Cream itself is lightweight (no oil) yet very conditioning/hydrating. Easily accepts water-soluble active ingredients as well as oil-soluble ones. I've even pushed the additional ingred % up to 20 (meaning 80% this cream, 20% added) without any separation issues. Ideal base cream for delivering actives. Personal favorite recipe calls for 5% straight Grapeseed Oil with 5% SebumREG oil active + Panthenol 1% + E Ac.. ...»
I have a blind faith of this Pre Liposome Microemulsion, especially it is made in Japan & of Squalane & Lecithin which I am fond of. I mixed it with Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 peptides liposome emulsion & some other water actives like Glucosamine, Niacinamide, Glutathione etc and the serum was very smooth and moisturizing. As it claims, it penetrates into the skin very well. I will mix it with oil soluble actives in my next batch. .. ...»
This is an excellent additive for increased absorption into the skin. I personally incorporate it with the ceramide lamellar crystal emulsion and multi lamellar base cream V2. The final product delivers a soothing, calming, super moisturizing liquid that penetrates the skin and helps the healing of severe skin issues such as mine (ichthyosis, keratosis). I highly recommend this formulation for those who are not getting any relief from other products and prescription topicals. My skin is finally .. ...»
I' m not sure about this: "11% solution gives 1% EGCG content in final product." What is the weight of final product? .. ...»
Vesna Hanich
It is true, this product does leave the skin silky smooth! I can highly recommend using it in your masks... ...»
Mati Fuller
I am 69 and I have used this product for two years almost every day at a high dose, adding it to my antioxidant day cream, with excellent results. For me it has a very high quality and effectiveness: reduction of wrinkles, hydrated skin, unified color without blemishes ... A product of 10, the same score that I give to John for the quality of the products he sells, his excellent description / use and the bibliographic contribution.En .. ...»
María Jesus
Tried this on my week-old rash from flea bites. Got an almost instant relief and rash healed in 2 days. Tried it on my daughter who has eczema for a very long time. The rashes calmed down after a few days and her skin is now healing well. Really great product. Just put in order for another jar.... ...»
This is great stuff. I add it to my liquid face soap and it does an excellent job in preventing acne and gently exfoliating the skin... ...»
Really loving this product. I make the best Centella toner and most concentrated ever. 2 g of centella extract dissolved in 10g of alcohol(you have to stir a lot) plus 88 grams of water and you get a very concentrated toner. Creams, toners, ampoules... all have only 0,1% of triterpenes, this toner i make have 1,4%. I am loving it, will see the results. .. ...»
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Buy Dimethyl Isosorbide (Arlasolve DMI) For Skin Care

Dimethyl isosorbide [DMI] is a solvent made from starch. It increases the solubility of many different active ingredients and increases their penetration into the skin. This reduces the amount of an active ingredient needed to have an effect, which is particularly good for reducing the irritation of harsher actives. Increasing skin penetration also increases the activity of a formulation, in several cases. Dimethyl isosorbide improves the overall properties of formulations, including skin feel and consistency. It can be used in many different types of products and is compatible with many compounds, including non-ionic surfactants.

Key benefits of Dimethyl Isosorbide (Arlasolve DMI) in skin care

  • Enhanced penetration of actives to the epidermis, enabling targeted delivery [1] [2] [5] [6] [7] [8] [9]
  • A lower level of skin irritation with a reduction in the required concentration level of aggressive actives [4] [8]
  • Improved formulation shelf stability [8]
  • Miscibility with most organic solvents and non-ionic surfactants.[8]
  • Incorporation within many product forms, including clear gels [4]
  • A long history of safe usage.
  • Ability to transport water soluble actives into skin, without recrystallization of the active [4] [8]
Dimethyl Isosorbide (Arlasolve DMI) skin care active ingredients
Product Code: BulkActives
Reward Points: 15
CAS#: 5306-85-4
Net weight: 50g / 1.76oz
Availability: In Stock
Price: $41.00
Reward Points: 1540

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Dimethyl Isosorbide (Arlasolve DMI)

Dimethyl isosorbide [DMI] is a compound produced from isosorbide, which comes from starch. It is a solvent, meaning it can be used to dissolve substances. It has been dubbed a “sustainable solvent,” as its source [starch] is widely available [3]. Dimethyl isosorbide is classified as a hydrotrope. Hydrotopes are small molecules that are able to increase the solubility of formulations [3]. The ability of dimethyl isosorbide to enhance solubility is superior to propylene glycol and ethyl alcohol, two commonly used solvents [7]. It is non-ionic [has no charge] and hydrophilic [water-loving]. This allows it to form a complex with water [9]. Also, dimethyl isosorbide has a low toxicity, so it does not cause irritation [7]. Dimethyl isosorbide has a low viscosity, meaning it is not very thick [9]. This contributes to its pleasant skin feel. Addition of dimethyl isosorbide is helpful for keeping formulations from being too thick and hard to pour. It can prevent “gelling” and cloudiness of formulations. It also increases the shelf stability of a product [8]. Overall, addition of dimethyl isosorbide can improve the properties of a product.

salicylic acid, an anti-acne treatment, to penetrate deep into the skin and have an effect quicker [1]. It helps target delivery of this active to problem areas in the skin. Dimethyl isosorbide acts as a carrier through the skin to deliver active ingredients into the skin layer where a problem exists [7]. Additionally, it increases the penetration of anti-oxidants. One study shows that without dimethyl isosorbide, an anti-oxidant showed no activity. With the addition of dimethyl isosorbide, it was able to penetrate the skin and protect against UV damage [6]. Dimethyl isosorbide also increases the activity of ferulic acid [2] and L-ascorbic acid [4, 8]. By adding dimethyl isosorbide, the delivery of a hydrophilic active into the skin increased 50% [8].

Dimethyl isosorbide can also make formulations less irritating. It can be combined with benzoyl peroxide, a common anti-acne medication that can result in skin irritation. Dimethyl isosorbide reduces the irritation potential of benzoyl peroxide and prevents its crystallization when applied to the skin [4]. Also, adding dimethyl isosorbide to a formulation can change the amount of active needed. By increasing solubility, it can allow for a greater amount of hard-to-dissolve actives, increasing the effectiveness of the product. It can also reduce the amount of active ingredient needed, as it allows more of the active to penetrate the skin and have an effect [8]. This is particularly useful for actives that are known to irritate the skin when used in high concentrations.

The compatibility of dimethyl isosorbide with many compounds makes it suited for different types of formulations. It can be used along with other penetration enhancers [9] or combined with oils [3]. Additionally, it can be mixed with surfactants, including nonionic surfactants [8]. It can be used in a wide variety of products, such as eye-zone treatments, makeup remover, scalp treatments, skin serums, and anti-acne treatments [8]. It can be used in deodorant gel sticks to provide better skin feel [4]. It can also be added to anti-wrinkle formulas [4]. Dimethyl isosorbide is an excellent addition to self-tanning formulas. It increases the solubility of dihydroxyacetone, a main ingredient of self-tanning products, which leads to a more uniform and intense tan that lasts longer [3].

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Arlasolve DMI Dimethyl Isosorbide skin care

Arlasolve DMI Dimethyl Isosorbide skin care
CAS#.: 5306-85-4
INCI: Dimethyl Isosorbide
Suggested Usage: 1 - 10%
Appearance: Clear oily liquid
Solubility: Dimethyl Isosorbide is soluble in a variety of ingredients including water, cottonseed oil, isopropanol, isopropyl myristate, propylene glycol, polysorbate 20, and polysorbate 80. It is insoluble in hydrogenated castor oil, lanolin, mineral oils or silicone oil (dimethicone).

Storage: Keep bottle upright. Must be stored in fridge. No do not freeze.

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