Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
This is the best product I have ever used on my skin and I tried a LOT of expansive brands. It helps with redness and overall skin tone. Please do not ever stop making this stuff... ...»
I' m not sure about this: "11% solution gives 1% EGCG content in final product." What is the weight of final product? .. ...»
Vesna Hanich
I am 69 and I have used this product for two years almost every day at a high dose, adding it to my antioxidant day cream, with excellent results. For me it has a very high quality and effectiveness: reduction of wrinkles, hydrated skin, unified color without blemishes ... A product of 10, the same score that I give to John for the quality of the products he sells, his excellent description / use and the bibliographic contribution.En .. ...»
María Jesus
Tried this on my week-old rash from flea bites. Got an almost instant relief and rash healed in 2 days. Tried it on my daughter who has eczema for a very long time. The rashes calmed down after a few days and her skin is now healing well. Really great product. Just put in order for another jar.... ...»
This is great stuff. I add it to my liquid face soap and it does an excellent job in preventing acne and gently exfoliating the skin... ...»
Really loving this product. I make the best Centella toner and most concentrated ever. 2 g of centella extract dissolved in 10g of alcohol(you have to stir a lot) plus 88 grams of water and you get a very concentrated toner. Creams, toners, ampoules... all have only 0,1% of triterpenes, this toner i make have 1,4%. I am loving it, will see the results. .. ...»
Just recently ordered this and LOVE! Green Tea EGCG truly is one of the most fantastic skincare actives out there. Very difficult to find good quality product (90%) and even harder to actually solubilize it! Love that it comes in pre-dissolved solution. I enjoy adding it at 1% (so 11% sol) to my serum formulations containing Niacinamide 5% + NAG 3%. Excellent for oily acne prone skin. *Only gripe... because the Pre-Dissolved Solution is SO heavy in propanediol (10 parts Propanediol for 1 part E.. ...»
Wonderful base cream! Only multi-lamellar structured cream I've found on the market. Cream itself is lightweight (no oil) yet very conditioning/hydrating. Easily accepts water-soluble active ingredients as well as oil-soluble ones. I've even pushed the additional ingred % up to 20 (meaning 80% this cream, 20% added) without any separation issues. Ideal base cream for delivering actives. Personal favorite recipe calls for 5% straight Grapeseed Oil with 5% SebumREG oil active + Panthenol 1% + E Ac.. ...»
excellence product, very good and made my skin soft and smooth just like baby's skin. Thank you john.. ...»
The Pre-dissolved solution is excellent. Ferulic Acid is an amazing skincare ingredient (potent antioxidant, protects other sensitive antioxidants from light degradation, UV protection) but is absolutely ineffective if it isn't solubilized correctly. Makes adding to any Serum Base or w/o emulsion easy. Love using it (at 6%; so active 0.5%) with the Resveratrol Fluid (10%; active 1%) and Green Tea Extr for potent nighttime brightening treatment... ...»
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Buy Yeast Beta Glucan (Beta 1-3 Glucan) For Skin Care

Glucan is a polymer, produced from glucose molecules in fungi, seaweed and other organisms. Many types of this polymer exist, but yeast beta-glucan has the optimal structure and size for biological activity. It has significant effects in wound healing – glucan is already used to treat burn patients, as it promotes regeneration of the skin, reduces pain and improves scar appearance. Furthermore, it is able to activate the immune system to fight against infections, making it additionally useful in open wound care. Additionally, it helps the skin to maintain its barrier function after damage by chemicals, such as detergents. The antioxidant properties of this polymer help protect the skin cells against UV or other sources of oxidative damage. Skin ageing symptoms, such as darkening, sunburn and collagen degradation, can also be reduced by applying this compound.

Key benefits of Yeast Beta Glucan in skin care:

  • Sun damage protection [1], [5], [11]
  • Sun damage repair [1], [5], [11]
  • Wound healing support [1], [4]–[8]
  • Anti-bacterial [9], [10]
  • Scar care [8]
  • Lightening & brightening [1]
  • Antioxidant [1], [5], [11]
  • Restore barrier function [5]
Yeast Beta Glucan (Beta 1-3 Glucan) skin care active ingredients
Product Code: BulkActives
Assay: 70%
CAS#: 9012-72-0
Net weight: 30g /1.06oz
Availability: In Stock
Price: $13.70

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Yeast Beta Glucan (Beta 1-3 Glucan)

About Beta Glucan Yeast ( Beta 1-3 Glucan) in DIY Skin Care

Beta-glucan is a natural polymer with a fiber-like structure, produced by joining together a large number of glucose molecules. It is  said to have “tremendous health-promoting applications” [1]. This polymer can be obtained from many sources, among them cereals, seaweeds and fungi, but the molecules produced in each organism slightly differ [2]. However, it is known that glucans of large mass and triple helix structure are the most biologically active, and this type of glucan is produced in yeast [3]. In addition, the structure of this glucan is also specially adapted, producing a heavy, but water-soluble polymer that strongly activates the biological response [2]. The areas where beta-glucan is used are activating the immune system, fighting bacteria and other infectious agents, reducing tumor growth and others. It even has an inhibitory effect on adipocytes, the fat-storing cells [4]. In recent years, skincare researchers have been developing new uses for this component as well.

Beta-glucan is very useful in wound care. It stimulates regeneration of the epithelium, improves collagen deposition, and helps attract the cells of immune system to the wound site [1]. In skin cell experiments, addition of yeast beta-glucan resulted in faster repair of the damage site and regrowth of the outer layer of skin [4], [5]. It was shown to effectively enhance wound closure in diabetic animals – this condition causes impaired wound healing, so addition of supporting agents is particularly required [6]. Beta-glucan applications are also useful in treating burn wounds, since the polymer is able to protect the tissue from oxidative damage [7]. Combined with a collagen matrix, beta-glucan is already used to treat human wounds in clinical care, resulting in less pain, improved healing, and better scar appearance [8]. Since the immune response is enhanced by fungal glucan, it supports the natural defenses against bacteria and other infections [9]. This is also useful in wound care, for example, glucan may be used in combination with antibiotics to prevent wound infections by Staphylococcus [10].

The antioxidant properties of beta-glucan are also utilised in anti-ageing and sunscreen applications. This polymer can reduce the oxidative damage from various sources, including chemicals and UV. Glucan from yeast is the most studied in this respect, with many experiments confirming its effectivenes, and even the ability to restore the functions of other antioxidants [1]. For example, applying 0.2 % glucan-containing emulsion for only 5 days was enough to completely protect certain skin molecules from the effects of UV irradiation [5]. A similar beta-glucan from another species of fungus was found to reduce various aspects of UV damage. Namely, in irradiated mouse the polymer decreased the amounts of inflammatory signals and collagen-degrading enzymes, protected the keratinocytes (skin cells) from cell death, and restored normal levels of natural antioxidants [11].

Treatment of skin with beta-glucan can also improve its barrier function. Volunteer skin, pre-treated with glucan-containing cream (0.04 to 0.4 % concentrations) for 2 weeks, showed significant resistance to damage from a detergent, measured by a reduced water loss [5]. This is also useful in treating aged skin symptoms. In addition, this polymer also improves aged skin appearance by other mechanisms: fungal glucan can increase collagen content, cell proliferation, reduce sunburn, and prevent melanin formation and thus darkening of the skin [1].

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Yeast Beta Glucan in skin careYeast Beta Glucan in skin care 

Assay: 80%
Latin name: Saccharomyces cerevisiae
Appearance: beige powder
Solubility:water (pre-dissolve in small amount of water first, then add to cream or serum)
Suggested percentage: No data available - up to customer's discretion.

Storage: Cool, dry place. Do not freeze. Keep away from light and moisture!
Country of origin: China
[1]          B. Du, Z. Bian, and B. Xu, “Skin Health Promotion Effects of Natural Beta-Glucan Derived from Cereals and Microorganisms: A Review,” Phytother. Res., vol. 28, no. 2, pp. 159–166, Feb. 2014.
[2]          D. B. Zeković, S. Kwiatkowski, M. M. Vrvić, D. Jakovljević, and C. A. Moran, “Natural and Modified (1→3)-β-D-Glucans in Health Promotion and Disease Alleviation,” Crit. Rev. Biotechnol., vol. 25, no. 4, pp. 205–230, Jan. 2005.
[3]          D. J. Manners, A. J. Masson, and J. C. Patterson, “The structure of a β-(1→3)-d-glucan from yeast cell walls,” Biochem. J., vol. 135, no. 1, pp. 19–30, Sep. 1973.
[4]          Vetvicka, V. and Vetvickova, J., “β(1-3)-D-glucan affects adipogenesis, wound healing and inflammation,” Orient. Pharm. Exp. Med., vol. 11, no. 3, pp. 169–175, Sep. 2011.
[5]          F. Zulli, F. Suter, H. Biltz, and H. P. Nissen, “Improving skin function with CM-glucan, a biological response modifier from yeast,” Int. J. Cosmet. Sci., vol. 20, no. 2, pp. 79–86, Apr. 1998.
[6]          M. Berdal, H. I. Appelbom, J. H. Eikrem, Å. Lund, S. Zykova, L.-T. Busund, R. Seljelid, and T. Jenssen, “Aminated β-1,3-d-glucan improves wound healing in diabetic db/db mice,” Wound Repair Regen., vol. 15, no. 6, pp. 825–832, Nov. 2007.
[7]          H. Z. Toklu, G. Sener, N. Jahovic, B. Uslu, S. Arbak, and B. C. Yeğen, “beta-glucan protects against burn-induced oxidative organ damage in rats,” Int. Immunopharmacol., vol. 6, no. 2, pp. 156–169, Feb. 2006.
[8]          S. J. Delatte, J. Evans, A. Hebra, W. Adamson, H. B. Othersen, and E. P. Tagge, “Effectiveness of beta-glucan collagen for treatment of partial-thickness burns in children,” J. Pediatr. Surg., vol. 36, no. 1, pp. 113–118, Jan. 2001.
[9]          G. D. Brown and S. Gordon, “Fungal β-Glucans and Mammalian Immunity,” Immunity, vol. 19, no. 3, pp. 311–315, Sep. 2003.
[10]        A. B. Kaiser and D. S. Kernodle, “Synergism between poly-(1-6)-beta-D-glucopyranosyl-(1-3)-beta-D-glucopyranose glucan and cefazolin in prophylaxis of staphylococcal wound infection in a guinea pig model,” Antimicrob. Agents Chemother., vol. 42, no. 9, pp. 2449–2451, Sep. 1998.
[11]        K. H. Kim, S. J. Park, Y. J. Lee, J. E. Lee, C. H. Song, S. H. Choi, S. K. Ku, and S. J. Kang, “Inhibition of UVB-induced skin damage by exopolymers from Aureobasidium pullulans SM-2001 in hairless mice,” Basic Clin. Pharmacol. Toxicol., vol. 116, no. 2, pp. 73–86, Feb. 2015.

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