Supplier of: skin actives, cosmetic ingredients, cosmeceuticals, active ingredients, and skin care ingredients, for DIY skin care and cosmetics, and homemade skin care products.
This is the best product I have ever used on my skin and I tried a LOT of expansive brands. It helps with redness and overall skin tone. Please do not ever stop making this stuff... ...»
I' m not sure about this: "11% solution gives 1% EGCG content in final product." What is the weight of final product? .. ...»
Vesna Hanich
I am 69 and I have used this product for two years almost every day at a high dose, adding it to my antioxidant day cream, with excellent results. For me it has a very high quality and effectiveness: reduction of wrinkles, hydrated skin, unified color without blemishes ... A product of 10, the same score that I give to John for the quality of the products he sells, his excellent description / use and the bibliographic contribution.En .. ...»
María Jesus
Really loving this product. I make the best Centella toner and most concentrated ever. 2 g of centella extract dissolved in 10g of alcohol(you have to stir a lot) plus 88 grams of water and you get a very concentrated toner. Creams, toners, ampoules... all have only 0,1% of triterpenes, this toner i make have 1,4%. I am loving it, will see the results. .. ...»
Just recently ordered this and LOVE! Green Tea EGCG truly is one of the most fantastic skincare actives out there. Very difficult to find good quality product (90%) and even harder to actually solubilize it! Love that it comes in pre-dissolved solution. I enjoy adding it at 1% (so 11% sol) to my serum formulations containing Niacinamide 5% + NAG 3%. Excellent for oily acne prone skin. *Only gripe... because the Pre-Dissolved Solution is SO heavy in propanediol (10 parts Propanediol for 1 part E.. ...»
excellence product, very good and made my skin soft and smooth just like baby's skin. Thank you john.. ...»
I wished i could order this in a smaller amount of 50 gr. Can i get informed when it is available ? -------------------- A. It will not be sold in smaller amounts. The review rating is meant to be for the product, not the size in which it is sold :-(.. ...»
Excellent quality, very fine texture and disperses easily when used correctly. Arrived in just seven days to London, England and with a reasonable postage fee. Very pleased... ...»
D N Bay
The best, most potent and most stable form of Vitamin C. Makes quite a difference to the appearance of mature, photo-damaged skin - don't expect results over night but with consistent use your skin will look more even and radiant!.. ...»
This ingredient has done more for my skin than anything else I've ever used. I put it into a spray facial toner and use it morning and night. I noticed the effects immediately, they were that dramatic. I will use this forever, no question... ...»
Secure Payments
Orders Securely Processed Through PayPal
 Visa  Mastercard  Discover  American Express

SSL Certificate

As Featured On EzineArticles





Important Stuff

 All customers PLEASE read:

 the FAQ and Delivery Info pages!

Canadian Customers:

Any long delivery delays are caused by The Canada Border Services Agency.
I now ONLY offer EMS as a shipping option to Canada. 
This appears to have resolved most of the delays caused by The Canada Border Services Agency.

Please write your correct address:

We take NO responsibility for delivery issues caused by customers entering the wrong address in the checkout page


BulkActives is a part-time business. Orders are processed and mailed on Saturdays. (TimeZone Order Deadline Chart)

What we sell

We sell  COSMETIC RAW MATERIALS, which are meant to be used at an appropriate percentage in a cosmetic formulation of your devising. Please do not order our products unless you know how to formulate creams and lotions with it!  

Forgotten your password? Not receiving lost password emails? Can't create an account?

NO PROBLEM!  Just email me, and I will sort it all out.

Not receiving order status email updates?

Please check your JUNK mail folder for our emails, and mark them as NOT SPAM.

Failing to do so will result in NOT receiving ANY transaction / order status email updates.

Recipe % calculator


Sample Recipes

Download sample recipes RAR file



Please READ this before placing an order, and select the CORRECT shipping option for your country at checkout!

Due to Wuhan Pneumonia Virus (aka Covid-19) border restrictions and a reduction or cancellation of flights by airlines, we CAN ONLY ship to the counries listed below!

We have also been advised to expect delivery delays at your end, and yes, that INCLUDES USA customers!!!

UK customers, we are finally ABLE to ship to the UK.

We CAN ship to:

Registered Airmail and EMS:
NORTH AMERICA: USA (NOT including Hawaii and Guam), UK
ASIA: China, Japan, Korea, Vietnam,Thailand, Malaysia, Singapore, Hong Kong, Macau, Philippines
EUROPE: France, Netherlands, Germany, Poland, Denmark, Norway, Finland

EMS only ! (Do NOT select Registered Airmail at checkout)
EUROPE: Belgium, Switzerland, Sweden, Czech, Italy
OCEANIA: New Zealand, Australia

Registered Airmail only!
Cambodia, Spain, Austria, Slovakia, Bahrain, Turkey, Saudi Arabia, United Arab Emirates, Lithuania

IMPORTANT: If your country is NOT in the above lists, then we CANNOT ship to you at the moment.
If your country does not accept Registered Airmail, then do NOT select it from the shipping options at checkout!


Buy Carnosine (L-Carnosine) For Skin Care

Carnosine is a compound from two amino acids, produced naturally in the human brain and muscles. Most likely, it performs a protective function – carnosine neutralizes metal ions and is a powerful antioxidant. It is used in skin care to combat oxidative damage to DNA and proteins, such as that caused by UV exposure. Furthermore, carnosine can protect proteins, primarily collagen, from glycation. These qualities make it a promising molecule in the fight against ageing, as carnosine not only protects cellular components, but can improve the visual appearance, reduce roughness and fine lines. It also maintains the barrier function of the skin, both by simple hydration and complex effects in wound healing. Carnosine applications are of special importance to diabetes patients, as it helps alleviate several complications of this disease, among them xerosis, rapid AGE production, and impaired wound healing.

Key benefits Carnosine in skin care:

  • Glycation inhibitor and repair [1] [9]
  • Sun damage protection [3] [4]
  • Sun damage repair [3] [4]
  • Wound healing support [11] [12]
  • Moisturizing & hydration [13] [14]
  • Antioxidant [4] [5] [6]
  • Restore barrier function [8]
Carnosine (L-Carnosine) skin care active ingredients
Product Code: BulkActives
Assay: 99.8
CAS#: 305-84-0
Net weight: 15g / 0.53oz
Availability: In Stock
Price: $18.70

    - OR -   Add to Wish List
Add to Compare

Carnosine (L-Carnosine)

About Carnosine in DIY Skin Care

Carnosine is a molecule composed of two amino acids, β-alanine and histidine. It is naturally abundant in brain and muscle tissues, but, although it was discovered in the year 1900, its function in the body is still unclear [1]. It might regulate the pH of muscle cells, neutralize metal ions or act as an antioxidant, and it gained a lot of interest recently as some studies show it might be used in treating cancer, Alzheimer’s disease and even cell ageing [2].

Carnosine has been shown to protect human skin cells against UV radiation. Together with some other forms of radiation, UV causes mutations in DNA and protein damage that often lead to cancer. To combat this, use of DNA-protecting molecules in skin cosmetics was proposed [3]. Carnosine falls among these molecules due to its antioxidant properties. In a study on human skin cells, carnosine was shown to reduce the oxidative damage caused by the UV on both DNA and proteins [4]. It is also able to activate synthesis of other naturally produced antioxidants, such as glutathione peroxidase [5]. Carnosine and related molecules have even stronger antioxidative capability than vitamin E [6]. However, it is advisable to apply these two antioxidants together, not only for synergistic protective effects – vitamin E improves the delivery of carnosine, resulting in higher levels of this molecule in target tissue [7].

In the recent years, commercial sunscreen products started to include carnosine, and the benefits of it have been proven in studies of UV-irradiated skin. Compared to traditional sunscreens, carnosine-containing creams successfully prevented UV damage and resulted in a significantly better state of both DNA and protein (less oxidative damage) after the irradiation [3]. In a trial on volunteers with sensitive skin, carnosine showed a protective effect on skin barrier function (reduced water loss and perceived dryness after 28 days of usage). Biochemical experiments suggest that the cream achieved this by improving the skin and neural cell response to UV radiation [8].

Carnosine is also able to reduce the effects of glycation. This process occurs naturally during ageing and produces damaged forms of proteins, called advanced glycation end products (AGEs). Collagen is among the proteins most affected by this, and its glycation may be responsible for loss of elasticity or other negative consequences of skin ageing. Carnosine is a competitive target for glycation, thus protecting valuable proteins from it [9], [10]. Results from volunteer studies indicate that carnosine improves skin visual parameters, maintains firmness, reduces roughness, fine lines and oily appearance [7].

Another major application of carnosine in skin care is wound healing. A preparation with carnosine was shown to promote collagen synthesis, cell proliferation and migration, which result in faster wound closure [11]. Just like glycation protection, this benefit of carnosine is even more important for diabetes patients, as wound healing is impaired under this disease. Skin applications of carnosine have successfully activated healing in diabetic mice wounds [12]. Xerosis, another skin-affecting complication of diabetes, is also alleviated by applying a cream with carnosine, as this molecule has a hydrating effect [13]. This cream also increases skin thickness, blood circulation and quality of life in xerosis patients [14].
Assay: 99.8%
CAS#: 305-84-0
INCI: L Carnosine
Appearance: white powder
Solubility: water
Suggested percentage: 1% to 5%

Storage: Cool, dry place. Do not freeze. Keep away from light and moisture!
Country of origin: China
[1]          A. A. Boldyrev, S. C. Gallant, and G. T. Sukhich, “Carnosine, the protective, anti-aging peptide,” Biosci. Rep., vol. 19, no. 6, pp. 581–587, Dec. 1999.
[2]          C. Renner, N. Zemitzsch, B. Fuchs, K. D. Geiger, M. Hermes, J. Hengstler, R. Gebhardt, J. Meixensberger, and F. Gaunitz, “Carnosine retards tumor growth in vivo in an NIH3T3-HER2/neu mouse model,” Mol. Cancer, vol. 9, p. 2, 2010.
[3]          E. Emanuele, J. M. Spencer, and M. Braun, “An experimental double-blind irradiation study of a novel topical product (TPF 50) compared to other topical products with DNA repair enzymes, antioxidants, and growth factors with sunscreens: implications for preventing skin aging and cancer,” J. Drugs Dermatol. JDD, vol. 13, no. 3, pp. 309–314, Mar. 2014.
[4]          E. Emanuele, M. Bertona, F. Sanchis-Gomar, H. Pareja-Galeano, and A. Lucia, “Protective effect of trehalose-loaded liposomes against UVB-induced photodamage in human keratinocytes,” Biomed. Rep., vol. 2, no. 5, pp. 755–759, Sep. 2014.
[5]          M. Y. Kim, E. J. Kim, Y.-N. Kim, C. Choi, and B.-H. Lee, “Effects of α-lipoic acid and L-carnosine supplementation on antioxidant activities and lipid profiles in rats,” Nutr. Res. Pract., vol. 5, no. 5, pp. 421–428, Oct. 2011.
[6]          M. A. Babizhayev, “Biological activities of the natural imidazole-containing peptidomimetics n-acetylcarnosine, carcinine and L-carnosine in ophthalmic and skin care products,” Life Sci., vol. 78, no. 20, pp. 2343–2357, Apr. 2006.
[7]          M. A. Babizhayev, A. I. Deyev, E. L. Savel’yeva, V. Z. Lankin, and Y. E. Yegorov, “Skin beautification with oral non-hydrolized versions of carnosine and carcinine: Effective therapeutic management and cosmetic skincare solutions against oxidative glycation and free-radical production as a causal mechanism of diabetic complications and skin aging,” J. Dermatol. Treat., vol. 23, no. 5, pp. 345–384, Oct. 2012.
[8]          G. de C. Dieamant, M. D. C. Velazquez Pereda, S. Eberlin, C. Nogueira, R. M. Werka, and M. L. de S. Queiroz, “Neuroimmunomodulatory compound for sensitive skin care: in vitro and clinical assessment,” J. Cosmet. Dermatol., vol. 7, no. 2, pp. 112–119, Jun. 2008.
[9]          V. P. Reddy, M. R. Garrett, G. Perry, and M. A. Smith, “Carnosine: a versatile antioxidant and antiglycating agent,” Sci. Aging Knowl. Environ. SAGE KE, vol. 2005, no. 18, p. pe12, May 2005.
[10]        C. Rona, F. Vailati, and E. Berardesca, “The cosmetic treatment of wrinkles,” J. Cosmet. Dermatol., vol. 3, no. 1, pp. 26–34, Jan. 2004.
[11]        Q. Wessels, E. Pretorius, C. M. Smith, and H. Nel, “The potential of a niacinamide dominated cosmeceutical formulation on fibroblast activity and wound healing in vitro,” Int. Wound J., vol. 11, no. 2, pp. 152–158, Apr. 2014.
[12]        I. Ansurudeen, V. G. Sunkari, J. Grünler, V. Peters, C. P. Schmitt, S.-B. Catrina, K. Brismar, and E. A. Forsberg, “Carnosine enhances diabetic wound healing in the db/db mouse model of type 2 diabetes,” Amino Acids, vol. 43, no. 1, pp. 127–134, Jul. 2012.
[13]        A. Federici, G. Federici, and M. Milani, “An urea, arginine and carnosine based cream (Ureadin Rx Db ISDIN) shows greater efficacy in the treatment of severe xerosis of the feet in Type 2 diabetic patients in comparison with glycerol-based emollient cream. A randomized, assessor-blinded, controlled trial,” BMC Dermatol., vol. 12, p. 16, 2012.
[14]        G. Ciammaichella, G. Belcaro, M. Dugall, M. Hosoi, R. Luzzi, E. Ippolito, and M. R. Cesarone, “Product evaluation of Ureadin Rx Db (ISDIN) for prevention and treatment of mild-to-moderate xerosis of the foot in diabetic patients. Prevention of skin lesions due to microangiopathy,” Panminerva Med., vol. 54, no. 1 Suppl 4, pp. 35–42, Dec. 2012.

Write a review

Your Name:

Your Review: Note: HTML is not translated!

Rating: Bad           Good

Enter the code in the box below:

(c) BulkActives 2005-2023